tag:blogger.com,1999:blog-82317463149482127332024-02-01T21:45:17.195-08:00 Florida Cat NewsEU VISITORS BE ADVISED THAT GOOGLE USES COOKIES
TO COLLECT DATA LIKE YOUR LOCATION tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.comBlogger18125tag:blogger.com,1999:blog-8231746314948212733.post-6495421232141870012018-07-20T10:14:00.005-07:002021-12-11T18:57:49.684-08:00<div align="center" class="MsoNormal" style="text-align: center;"><span style="font-family: arial;"><b><span style="background-color: white;">AUGUST 2021 </span><span style="background-color: white; color: red; font-size: large;">- DUE TO COVID-19 LIMITING SPAY/NEUTER SURGERIES, ALLEY CAT ALLIES AND THE ALLIANCE FOR CONTRACEPTION IN CATS AND DOGS NOW ENDORSE THE SHORT TERM USE OF MA TO PREVENT PREGNANCIES IN CATS- SEE THEIR WEBSITES FOR MORE INFORMATION </span></b></span></div><div align="center" class="MsoNormal" style="text-align: center;"><span style="font-family: arial; font-size: x-large;"><b style="background-color: white;"><br /></b></span></div><div align="center" class="MsoNormal" style="text-align: center;">
<span style="font-family: arial; font-size: x-large;"><b style="background-color: white;">Edible Birth Control for Cats</b></span><br />
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<i><span style="font-family: arial; font-size: large;"><b>It works, is low risk, *<span style="background-color: yellow;">LOW COST</span>, </b></span></i><br />
<i><span style="font-family: arial;"><b><span style="font-size: large;">and can save millions of cats' lives</span>. </b></span></i><br />
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<i><span style="font-family: arial;">This blog is my opinion based on years of personal experience and dozens of hours of research. I am not a veterinarian. Megestrol Acetate is available by prescription only in the United States but can sometimes be purchased on EBAY under the name "Nonovulin" and through an online retailer named Venivet. Do thorough research and give careful consideration before making your own decision about obtaining or using Megestrol Acetate.</span></i></div>
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<i><span style="font-size: medium;"><b>It works -</b></span></i></span></div><div align="center" class="MsoNormal" style="text-align: center;"><span style="font-family: arial;"><b><i><br /></i></b>
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<span style="font-family: arial;">I have used both Feralstat and Nonovulin with success for over 10 years. A colleague writes about his positive experience on Birthcontrolforcats.com. Fairchild Feral Friends has used it for over a decade to stabilize colonies while T/N/R is being done. A Topix forum <i>(please see archived posts) </i>has caretakers from all over the country discussing their success. And it has been available without a prescription in pharmacies in Europe for more than 20 years. </span></div>
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<span style="font-family: arial; font-size: medium;"><b><i>It's low risk -</i></b></span></div><div style="text-align: center;"><span style="font-family: arial;"><b><i><br /></i></b></span></div>
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<span style="font-family: arial;"><span>The following French study took place after a consumer voiced concerns about side effects of megestrol acetate products for cat birth control. Even though the manufacturer's recommended dosage is much higher than the dose U.S. feral cat caretakers use, risk of side effects was determined to be .074 per 100K pills sold. An English translation as well as the original French study is available through the birthcontrolforcats.com website at </span><a href="http://www.birthcontrolforcats.com/cnpv.pdf">http://www.birthcontrolforcats.com/cnpv.pdf</a></span></div>
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<span>My own research (see archive) showed very little research in the U.S., and all at much higher doses. A European study was more extensive and showed very low risk of adverse reaction. </span><br />
<span><br /></span><span>Along with my feral colony, I have used Nonovulin successfully on two indoor cats for which surgery was high risk, with no negative side effects. </span></span></div><div align="left" class="MsoNormal"><span style="font-family: arial;"><br />
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<span style="font-family: arial; font-size: medium;"><b><i>It's low co</i></b><b><i>st</i></b></span></div><div style="text-align: center;"><span style="font-family: arial;"><b style="color: #402000;"><i><br /></i></b></span></div>
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<span style="background-color: white; font-family: arial;"><span>July of 2020 I paid $16 for 30 ten mg Nonovulin pills through an EBAY vendor.</span><span> My colony is currently 7 cats and my weekly birth control cost is 27 cents.</span></span></div><div style="text-align: left;"><span style="background-color: white; font-family: arial;"><span><br /></span></span></div><div style="text-align: left;"><span style="background-color: white; font-family: arial;"><span>Nonovulin is a megestrol acetate product available in pharmacies in Europe without a prescription. In the U.S. megestrol acetate is prescription only through veterinarians. </span></span></div><div style="text-align: left;"><span style="background-color: white; font-family: arial;"><span><br /></span></span></div><div style="text-align: left;"><span style="font-family: arial;"><br /></span></div><div style="text-align: left;"><span style="font-family: arial;"> <span style="font-size: medium;"> <b> My Colony</b></span><br />
<span face="arial, helvetica, sans-serif"><span style="background-color: white;"><br /></span></span><span face="arial, helvetica, sans-serif"><span style="background-color: white;">When I began feeding and dosing in September of 2019 there were 17 cats. There are now 7. There have been no births. I've used the chart below to determine dosage. I cut the 10 mg pills with a pill cutter and dissolve the dosage in a little water in a clear container so that I can see that the particles are well dissolved before adding them to one 22 oz can of wet cat food. </span></span></span></div><div style="text-align: left;"><span style="font-family: arial;"><span face="arial, helvetica, sans-serif"><span style="background-color: white;"><br /></span></span></span></div><div style="text-align: left;"><span style="font-family: arial;"><span face="arial, helvetica, sans-serif"><span style="background-color: white;">Please note that the </span><span><span style="background-color: #fcff01;">dosage is PER COLONY NOT PER CAT. </span><span style="background-color: white;"> </span></span></span></span></div><div style="text-align: left;"><span style="font-family: arial;"><br /></span></div><div style="text-align: left;"><span style="font-family: arial;"><br />
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<span style="font-family: arial;"><b><span style="background-color: white;">Dosage </span><u style="background-color: #f4cccc;">PER COLONY</u><span style="background-color: white;"> using Nonovulin 10 mg tablets</span></b></span></div>
<span style="font-family: arial;"><span style="background-color: yellow;"><span face="arial, helvetica, sans-serif"><br /></span></span><span face="arial, helvetica, sans-serif"><span style="background-color: white; color: #222222;"> </span><b><span style="background-color: white; color: #222222;"> Total # of Cats Dosage (dry)</span><span style="background-color: #ead1dc; color: #222222;"> <u>per colony </u></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> </span></b><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> < 5 cats 2.5 mg <b>ONCE a week</b></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 5-7 cats 5 mg <b>ONCE a week</b></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 8-11 cats 7.5 mg <b>ONCE a week</b></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 12-15 cats 5 mg <b>TWICE A WEEK</b></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 16-19 cats 7.5 mg<b> TWICE A WEE</b>K</span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 20-23 cats 8 mg <b>TWICE A WEEK</b></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 24-27 cats 10 mg <b>TWICE A WEEK </b></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 28-31 cats 11 mg <b>TWICE A WEEK</b></span><br style="background-color: white; color: #222222;" /><span style="background-color: white; color: #222222;"> 32-35 cats 12.5 mg <b>TWICE A WEEK</b></span><span style="background-color: yellow; color: white;"><span style="background-color: white;">c </span></span></span><br />
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<span style="background-color: yellow;"><span face="arial, helvetica, sans-serif"><span style="color: white;"><span style="background-color: white;"> 2.8 ml TWICE A WEEK 14 mg TWICE A WEEK</span></span></span></span><span style="background-color: yellow;"><span face="arial, helvetica, sans-serif"><br /></span></span>
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<span>This information was previously published on my site floridacatnews.com. </span><br />
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-77886218317730002402018-07-20T09:05:00.000-07:002018-07-20T14:14:52.966-07:00FDA Veterinary Adverse Event Voluntary Reporting MA<div class="separator" style="clear: both; text-align: center;">
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<span style="font-size: large;"><b>From the FDA site, veterinary adverse event volunteer reporting for Megestrol Acetate , 1987 - April 2012</b></span></div>
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<b><span style="font-size: small;"><a href="http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm055369.htm#How_to_Use_These_Reports">http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm055369.htm#How_to_Use_These_Reports</a></span></b></div>
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(options are alphabetical and broken in to 4 groups - scroll through to find medication you're looking for.) </div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-3857789312281350452018-07-20T08:24:00.000-07:002018-07-20T14:14:30.735-07:00Megestrol acetate PubMed research - summary<div class="MsoNormal">
<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Five studies/cases involved high blood sugar/ glucose intolerance and diabetes. One death was reported, but the cat was 18 and had a previous history of diabetes and corticosteroid treatment. Three studies/cases reported that the diabetes reversed after the MA was discontinued, sometimes with insulin therapy and sometimes without. One of the two remaining studies was a survey of insured pet owners in the UK (total number surveyed not given) and reported that the incidence of diabetes among cats in the survey was 1 in 230, but “significantly higher” among cats which had received MA. At less than one half of one percent “significantly higher” could still be a very low number. The last study doesn’t mention if the blood sugar issue resolved after the study.</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Mammary swelling and growths were also discussed. One cat, only 1.5 years old, had 121 days of treatment for a skin condition with not just MA, but a host of other drugs. After the MA treatment the cat experienced mammary swelling and although that resolved, when the skin condition returned, the owner elected to euthanize the cat. In another study, nine cats had enlarged mammary glands. Four were spayed and the swelling went away, and in the other five the lesions were excised and did not return during the follow up period. Finally, the tissue of 17 cats treated with MA and with mammary growths was analyzed. Fourteen were benign, three were cancerous. </span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Two studies involved “adrenocortical function” and even with a medical dictionary much of it was over my head. The first studied 20 cats, 16 of which received MA and 4 of which served as controls, concluded that “the effects of megestrol acetate on glucose tolerance were overshadowed by the unforeseen intolerance caused by chemical restraint with acepromazine maleate and ketamine hydrochloride.” The second study had 7 cats which received MA and 7 cats which received Prednisolone for 16 days and were observed for 30. It stated that on day 8 both groups had suppressed cortisol levels, on day 15 the MA group had more marked changes, and by day 30, 6 of 7 cats receiving prednisolone had recovered their adrenal reserves, but only 3 of 7 receiving MA had. Other side effects were “occasionally noted in both groups”. </span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Three studies/cases either studied or reported changes in the uterus of cats receiving MA. In 1974 in Oslo, 244 cats were given 2.5mg of MA for 30 weeks by their owners to study its use as a birth control. There were no pregnancies but one cat who received the MA for three years developed Pyometra. Another study dosed spayed kittens for 12 weeks then observed them for another 12 weeks. It doesn’t give the number, but some had uterine horns increase in length and diameter, folds in the endometrium, and one kitten developed pyometra. The third case was of an intact 12 year old Siamese cat that had been on MA for 10 years intermittently as a birth control, and had developed a benign growth in the uterus.</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Increased appetite, personality changes, and depression were reported in 21 cats given MA for skin issues.</span></b></div>
tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-24322658904610900792018-07-20T08:22:00.000-07:002018-07-20T14:14:09.652-07:00Megestrol acetate research PubMed - text<div align="center" class="MsoNormal" style="text-align: center;">
<b><span style="color: blue; font-size: 18pt;">Studies found on PubMed by searching “Megestrol Acetate Cats”</span></b></div>
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<b>Study title is in <span style="color: blue;">blue</span></b></div>
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<b>Copied studies in to a single Word document</b></div>
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<b>May contain spelling / punctuation / other errors</b></div>
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<b>Where full text was available, it was copied</b></div>
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<b><span style="font-size: 16pt;">1) <a href="http://www.ncbi.nlm.nih.gov/pubmed/22015158" style="color: blue; text-decoration: underline; text-underline: single;">Effects of the GnRH analogue deslorelin implants on reproduction in female domestic cats.</a></span></b></div>
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Toydemir TS, Kılıçarslan MR, Olgaç V.</div>
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Theriogenology. 2012 Feb;77(3):662-74. Epub 2011 Oct 19.</div>
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PMID:22015158 </div>
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[PubMed - in process] </div>
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Abstract</div>
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The aim of the present study was to investigate the safety and efficacy of deslorelin, a GnRH agonist, implants in suppressing estrus behavior and matings in a controlled ambient environment in feline queens in the presence of a tomcat. Local and utero-ovarian side effects of deslorelin implants were also investigated. The queens were housed in groups and assigned to one of three treatments: group 1 received 9.5 mg deslorelin implants (N = 14), group 2 received 5 mg megestrol acetate tablets and 9.5 mg deslorelin implants (N = 7), and group 3 were given placebo implants (N = 7). All implants were placed subcutaneously cranial to the interscapular region under xylazine hydrochloride sedation. Ovarian activity was monitored by fecal estradiol (E(2)) analyses. The animals were observed daily and checked individually at three-day intervals for behavioral signs of estrus. After 18.5 mo of trial, queens were ovariohysterectomized, and ovaries and uteri were weighed and evaluated histologically. E(2) levels were significantly lower in group 1 and 2 than in group 3 with an average of 128.48 ± 19.97 ng/g, 90.44 ± 7.16 ng/g and 283.26 ± 39.21 ng/g, respectively, excepting the first week of treatment. After inserting implants an initial estrus-like increase in fecal E(2) concentrations occurred in all treated queens except one female in group 2. Ovarian and uterine weights were significantly different among the groups (P < 0.01), and were lowest in groups 1 and 2. Primordial and primary follicle numbers were significantly higher in groups 1 and 2 than in group 3 (P < 0.001). Endometrial gland, antral follicle, and corpus luteum (CL) numbers were highest in group 3 (P < 0.01, 0.001, and 0.001, respectively) compared with groups 1 and 2. Deslorelin implants successfully suppressed estrus behavior and E(2) secretion in queens for 18.5 mo of the study period. Further investigations are needed to demonstrate the effects of GnRH agonists on ovarian interstitial tissue.</div>
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Copyright © 2012 Elsevier Inc. All rights reserved.</div>
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<b><span style="font-size: 16pt;">2)<a href="http://www.ncbi.nlm.nih.gov/pubmed/18827849" style="color: blue; text-decoration: underline; text-underline: single;">A rare case of uterine adenomyosis in a Siamese cat.</a></span></b></div>
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Bulman-Fleming J.</div>
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Can Vet J. 2008 Jul;49(7):709-12.</div>
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PMID: 18827849</div>
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[PubMed - indexed for MEDLINE] <span style="display: none; font-size: 8pt;">Top of Form</span></div>
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Can Vet J. 2008 July; 49(7): 709–712. </div>
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PMCID: PMC2430406</div>
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<a href="http://www.ncbi.nlm.nih.gov/pmc/about/copyright.html" style="color: blue; text-decoration: underline; text-underline: single;">Copyright</a> and/or publishing rights held by the Canadian Veterinary Medical Association</div>
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Julie Bulman-Fleming</div>
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<span style="color: #3e3e3e;">Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4</span></div>
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<span style="color: #3e3e3e;">Address all correspondence and reprint requests to Dr. Bulman-Fleming.</span></div>
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<span style="color: #3e3e3e;">Dr. Bulman-Fleming’s current address is Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, Ontario N1G 2W1.</span></div>
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<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#__abstractid967967#__abstractid967967" style="color: blue; text-decoration: underline; text-underline: single;">Abstract</a></div>
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<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#__trans-abstractid968928#__trans-abstractid968928" style="color: blue; text-decoration: underline; text-underline: single;">Résumé</a></div>
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<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#__ref-listid1331876#__ref-listid1331876" style="color: blue; text-decoration: underline; text-underline: single;">References</a></div>
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A 12-year-old, intact female, Siamese cat was presented to the referring veterinarian with a 2-day history of persistent vomiting, inappetence, and abdominal distention. The cat had been seen 2 wk prior for routine vaccinations and was showing estrus behavior at that time. Over the past 10 y, she had been vaccinated yearly and had been treated intermittently with megestrol acetate to suppress estrus. The referring veterinarian performed a complete blood (cell) count (CBC) and serum biochemical profile; results from both test panels showed no significant abnormalities. An in-clinic urinalysis was performed and the urine specific gravity was concentrated beyond the upper limit of the refractometer, and there was 3+ proteinuria. The tentative diagnosis was pyometra; the cat was hospitalized overnight and received lactated Ringer’s solution, IV. The case was then referred to the Small Animal Clinic at the Western College of Veterinary Medicine Teaching Hospital.</div>
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On physical examination, a firm, painful mass was detected within the caudoventral part of the abdomen. The cat was afebrile and tachycardic (240 beats/min; normal 160 to 220 beats/min). A superficial mobile mass was present along the ventral aspect of the trachea towards the thoracic inlet. The remaining physical examination revealed no other abnormalities.</div>
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Blood samples were submitted for a CBC (Abbott Cell-Dyn 3500R; Abbott Laboratories, St. Laurent, Quebec) and a resting thyroxine hormone level (Immulite; Inter-medico, Markham, Ontario). Results from the CBC were unremarkable, and from her resting T4, they were within the reference interval (45 nmol/L; reference interval, 13 to 50 nmol/L). Radiographs of the abdomen revealed convoluted, fluid-filled tubular structures extending from the pelvis to mid-abdomen; they were interpreted as a distended uterus (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/figure/f1-cvj49pg709/" style="color: blue; text-decoration: underline; text-underline: single;">Figure 1</a>). Feline uteri are not usually visible on plain radiographs (<a href="http://www.ncbi.nlm.nih.gov/pubmed/15935839" style="color: blue; text-decoration: underline; text-underline: single;">1</a>). Ultrasonographs of the abdominal cavity further defined the structures as an enlarged uterus, with the left horn measuring approximately 1.5 cm in diameter and the right horn and body measuring approximately 1.0 cm in diameter. The normal uterine outer diameter in a cat varies from 0.39 to 0.70 cm, depending on the stage of the estrus cycle (<a href="http://www.ncbi.nlm.nih.gov/pubmed/15935839" style="color: blue; text-decoration: underline; text-underline: single;">1</a>). The uterine width is largest in the luteal phase, but it enlarges further with uterine lesions or previous progestin treatment (<a href="http://www.ncbi.nlm.nih.gov/pubmed/15935839" style="color: blue; text-decoration: underline; text-underline: single;">1</a>). The uterine walls appeared thin, but the lumen was filled with heterogeneous material that did not appear to be fluid. Ultrasonographs also showed 2 cysts (0.9 cm and 0.18 cm) on the left ovary. No other abdominal abnormalities were detected. Urine was collected by cystocentesis and submitted for a complete urinalysis, the results of which were unremarkable. Ultrasonographs showed that the mass in the ventral part of the neck was cystic. Further testing was declined by the owner, and the cyst has since resolved spontaneously.</div>
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<span style="color: blue;"><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/figure/f1-cvj49pg709/" style="color: blue; text-decoration: underline; text-underline: single;" target="figure"><span style="text-decoration: none;"><shapetype coordsize="21600,21600" filled="f" id="_x0000_t75" o:preferrelative="t" o:spt="75" path=" m@4@5 l@4@11@9@11@9@5 xe" stroked="f"><stroke joinstyle="miter"></stroke><formulas><f eqn="if lineDrawn pixelLineWidth 0 "></f><f eqn="sum @0 1 0 "></f><f eqn="sum 0 0 @1 "></f><f eqn="prod @2 1 2 "></f><f eqn="prod @3 21600 pixelWidth "></f><f eqn="prod @3 21600 pixelHeight "></f><f eqn="sum @0 0 1 "></f><f eqn="prod @6 1 2 "></f><f eqn="prod @7 21600 pixelWidth "></f><f eqn="sum @8 21600 0 "></f><f eqn="prod @7 21600 pixelHeight "></f><f eqn="sum @10 21600 0 "></f></formulas><path gradientshapeok="t" o:connecttype="rect" o:extrusionok="f"></path><lock aspectratio="t" v:ext="edit"></lock></shapetype><shape alt="Figure 1" coordsize="21600,21600" id="_x0000_s1036" o:button="t" style="height: 117pt; width: 75pt;" type="#_x0000_t75"><imagedata o:href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/bin/cvj49pg709f1.gif" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image001.gif"></imagedata></shape></span></a></span></div>
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<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/figure/f1-cvj49pg709/" style="color: blue; text-decoration: underline; text-underline: single;"><b><span style="color: #004080; text-decoration: none;">Figure 1</span></b></a> </div>
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<span style="color: #5e5e5e;">Ventrodorsal radiograph showing diffusely enlarged and distended uterine horns (arrows).</span></div>
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The cat became markedly depressed throughout the day, so an exploratory laparotomy was scheduled for later that evening. The cat was premedicated with hydromorphone (Hydromorphone hydrocholoride injection USP 2 mg/mL (generic); Sabex, Boucherville, Quebec), 0.1 mg/kg bodyweight (BW), IM, and anesthesia was induced with propofol (Diprivan; Novopharm, Toronto, Ontario), 6 mg/kg BW, IV, and maintained on 1.0 L/min oxygen and 1.5% isoflourane (Isoflo; Abbott Laboratories, St. Laurent, Quebec).</div>
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A ventral midline incision was made through the abdominal wall, whereupon enlarged, firm, nodular uterine horns were immediately visible. The entire length of both uterine horns was affected, as was the uterine body. The left ovary had 2 cystic structures, as detected on ultrasonographs. A routine ovariohysterectomy was performed, though ligatures were placed prior to clamping the uterine body, since the tissue was friable. The uterine vessels were ligated separately from the uterine body, which was then singly ligated at the cervix where, grossly, the tissue was normal. Urine was collected via cystocentesis for bacteriological culture. The uterine stump was wrapped in omentum, the peritoneal cavity was lavaged, and the abdominal wall was closed routinely. Cefazolin (Novopharm, Toronto, Ontario), 22 mg/kg BW, IV, was given prior to the surgery and, thereafter, every 90 min throughout the procedure. The uterine horns and body were opened, examined grossly, fixed in formalin, and submitted for light microscopic examination.</div>
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Postoperatively, the cat received cefazolin (Novopharm), 22 mg/kg BW, IV, q12h, hydromorphone (Sabex), 0.05 mg/kg BW, IM, q4h, and meloxicam (Metacam; Boerhringer-Ingelheim, Laval, Quebec), 0.1 mg/kg BW, SC, q24h. She became dysphoric after receiving hydromorphone, so the analgesic was changed to buprenorphine (Buprenex; Reckitt and Colman Pharmaceuticals, Richmond, Virginia, USA), 0.01 mg/kg BW, SC, q6h. The buprenorphine treatment was continued at 0.01 mg/kg BW, SC, q8h for 2 d, and meloxicam (Boerhringer-Ingeheim) was given, 0.1 mg/kg BW, PO, q12h for 5 d, after surgery. The antibiotic was changed the following day to amoxicillin-clavulanic acid (Clavamox; Pfizer Animal Health, Kirkland, Quebec), 62.5 mg, PO, q12h for 10 d, and the cat was discharged 4 d postoperatively. No further health concerns were reported in the 6 mo following discharge.</div>
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Histopathologic examination of the uterus revealed diffuse adenomyosis of both horns and the body of the uterus. There was endometrial and myometrial hyperplasia, which obliterated the uterine lumen. The walls were at least twice the normal thickness. In areas where the lumen was not obliterated, it was filled with white, adherent material. Endometrial tissue was found within the myometrium, forming glandular structures (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/figure/f2-cvj49pg709/" style="color: blue; text-decoration: underline; text-underline: single;">Figure 2</a>). The abnormal endometrial tissue appeared to be functional, and no evidence of malignancy was found. Histopathologic examination of the ovaries showed numerous follicles at various stages of development, numerous corpora lutea, and several cystic structures.</div>
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<span style="color: blue;"><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/figure/f2-cvj49pg709/" style="color: blue; text-decoration: underline; text-underline: single;" target="figure"><span style="text-decoration: none;"><shape alt="Figure 2" coordsize="21600,21600" id="_x0000_s1035" o:button="t" style="height: 60pt; width: 75pt;" type="#_x0000_t75"><imagedata o:href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/bin/cvj49pg709f2.gif" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image002.gif"></imagedata></shape></span></a></span></div>
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<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/figure/f2-cvj49pg709/" style="color: blue; text-decoration: underline; text-underline: single;"><b><span style="color: #004080; text-decoration: none;">Figure 2</span></b></a> </div>
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Photomicrograph of a uterine horn section showing endometrial proliferation and invasion of the myometrium characteristic of uterine adenomyosis (arrows). Hematoxylin and eosin. Bar = 1000 μm.</div>
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Adenomyosis is defined as a benign condition where endometrial glands and stroma occur in a disorganized fashion deep within the myometrium (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>,<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b3-cvj49pg709#b3-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">3</a>). There is also characteristic myometrial hyperplasia surrounding the adenomatous tissue. Diffuse disease is known as uterine adenomyosis, while isolated foci are termed uterine adenomyomata (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). Uterine adenomyosis is a rare disorder of domestic animals, though it does occur with variable frequency in humans (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>,<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b4-cvj49pg709#b4-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">4</a>). Uterine adenomyosis is thought to occur due to endometrial invagination and invasion of the underlying muscular layers, though it may also occur outside the uterus through aberrant development of the Mullerian ducts (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). The pathogenesis is not well understood, though increased estrogen, abnormal musculature, and increased luminal pressure have been implicated (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>,<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b4-cvj49pg709#b4-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">4</a>,<a href="http://www.ncbi.nlm.nih.gov/pubmed/11485920" style="color: blue; text-decoration: underline; text-underline: single;">5</a>). The immune responses in adenomatous uteri are also abnormal (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b4-cvj49pg709#b4-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">4</a>,<a href="http://www.ncbi.nlm.nih.gov/pubmed/11485920" style="color: blue; text-decoration: underline; text-underline: single;">5</a>). Adenomyosis may co-occur with leiomyomata, polyps, and adenocarcinoma (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). Endometriosis shares several characteristics with adenomyosis, but in endometriosis, aberrant endometrium is found only outside the uterus and endometriosis occurs only in menstruating species (primates).</div>
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In women, the most common clinical signs of uterine adenomyosis are dysmenorrhea and menorrhagia, followed by abdominal and pelvic pain and reproductive difficulties (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). Approximately 35% of women are asymptomatic (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). The rare published veterinary cases have been without clinical signs (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>), making this cat unusual in that she was presented for vomiting, inappetence, and abdominal pain. In human cases, as in this feline case, definitive diagnosis prior to surgical removal of the uterus is difficult. An enlarged uterus may be noted on ultrasonographs or radiographs, but magnetic resonance imaging is the preferred diagnostic test in women (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b7-cvj49pg709#b7-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">7</a>). Light microscopy is required to confirm the diagnosis. Hysterectomy or ovariohysterectomy is often the definitive treatment.</div>
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The hormonal profile in women with adenomyosis is atypical. Endometrial glands in adenomyosis express more lutenizing hormone, estrogen, and progesterone receptors than in the normal uterus (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). Adenomyotic glands have also been found to secrete excess estrogen and to have higher than normal estrogen sulphatase and aromatase levels, 2 enzymes that increase conversion of androgens to estrogen and also increase estrogen binding (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). These findings, coupled with the success of anti-estrogenic drugs as treatment, support the theory of excess estrogen being a causal factor. The excess estrogen levels in affected women may arise from excess circulating progestins, which elevate aromatase activity, estrogen receptor concentration, and epidermal growth factors (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b2-cvj49pg709#b2-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">2</a>,<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>). Initially, progestins oppose estrogenic effects, hence duration of treatment may be important with respect to disease (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b8-cvj49pg709#b8-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">8</a>). The prevalence of adenomyosis is unexpectedly high in women receiving chemotherapy with the selective estrogen receptor modulator tamoxifen, which has estrogenic effects (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b4-cvj49pg709#b4-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">4</a>,<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b7-cvj49pg709#b7-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">7</a>). Since this cat received megestrol acetate frequently throughout her life, the exogenous progestins are suspected to have increased her risk for disease. Increased progesterone from corpora lutea, which were numerous in the ovaries of this cat, could also have increased estrogen levels over time through the same mechanisms as exogenous progestins, and thus have contributed to the adenomyosis (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>). It is difficult to determine whether the uterine lesions contributed to abnormal ovarian activity or vice versa.</div>
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Adenomyosis is correlated with uterine hyperplasia in women and zoo felids (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b4-cvj49pg709#b4-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">4</a>,<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>). Endometrial hyperplasia is a reported sequela to progestin therapy in domestic animals; pyometra and other reproductive problems are also potential risks (<a href="http://www.ncbi.nlm.nih.gov/pubmed/15935839" style="color: blue; text-decoration: underline; text-underline: single;">1</a>). Munson et al (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>) found that zoo felids treated with melegestrol acetate were at a 3.6 times higher risk of endometrial hyperplasia and associated reproductive disease than were untreated cats. Progestin treatment significantly increased uterine coiling, curving, and glandular proliferation beyond the changes that normally occur throughout the estrus cycle (<a href="http://www.ncbi.nlm.nih.gov/pubmed/15935839" style="color: blue; text-decoration: underline; text-underline: single;">1</a>). Synthetic progestins are commonly used for estrus suppression and estrus cycle control in both domestic and zoological animals, the most common being megestrol acetate, melegestrol acetate, and medroxyprogesterone acetate (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b9-cvj49pg709#b9-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">9</a>). These compounds block gonadotropin releasing hormone (GnRH) production or release. Common side effects in domestic cats and dogs include endometrial hyperplasia, mammary development, and insulin resistance (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>,<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b9-cvj49pg709#b9-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">9</a>). Munson et al (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>) also found progestin therapy was associated with hydrometra, mucometra, and endometrial mineralization. Cats appear particularly sensitive to adrenocortical suppression and routine doses can cause hypoadrenocorticism (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>,<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b8-cvj49pg709#b8-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">8</a>,<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b9-cvj49pg709#b9-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">9</a>). In this cat, there was no evidence of altered steroid profile or insulin resistance, as indicated by normal electrolyte and glucose parameters. The dose and duration of the megestrol acetate treatment previously prescribed for this cat was unknown. Megestrol acetate is not labeled for use in cats, and treatment regimes are variable. Suggested protocols range from 2.5 to 5.0 mg/cat, PO, q24 h for 3 d, if administration is started during estrus, to 2.5 to 5.0 mg/cat, PO, q24 h for 8 to 10 wk, if it is started in diestrus (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b8-cvj49pg709#b8-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">8</a>). Treatment with 2.5 mg, PO, once weekly for up to 18 mo is suggested for suppression of estrus if it is started in anestrus (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b8-cvj49pg709#b8-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">8</a>). Varied protocols also exist for its use in treating many feline dermatological problems.</div>
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Medical treatment of adenomyosis in women has met with variable success. Oral contraceptives, progestins, antiprogestins, anti-estrogen antibodies, GnRH analogues, and danazol-impregnated intrauterine devices have all been used, with anti-estrogen antibodies, antiprogestins, such as gestrinone or indomethacin, and danazol having the highest success (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b7-cvj49pg709#b7-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">7</a>). Danazol is a weak androgenic compound that is suspected to act via inhibition of sex steroid production and is a mainstay in endometriosis therapy (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b8-cvj49pg709#b8-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">8</a>). Severe cases require partial to complete hysterectomy. In veterinary medicine, where reproductive conservation is often less critical, ovariohysterectomy is the most commonly recommended treatment (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>).</div>
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Both adenomyosis and the prescribed treatments can adversely affect the ability to conceive. This is of concern in rare zoo felids receiving long-term progestin treatment to suppress estrus, as many of these animals will be bred in the future and are genetically valuable. Munson et al (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>) caution against the use of exogenous progestins in potential breeding animals; they recommend early breeding or alternating breeding with progestin therapy to maintain reproductive health.</div>
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Uterine adenomyosis has been described rarely in the veterinary literature (<a href="http://www.ncbi.nlm.nih.gov/pubmed/15943119" style="color: blue; text-decoration: underline; text-underline: single;">10</a>). Uterine disease is much less common in the cat than in the dog (<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;">6</a>). Pack (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430406/#b3-cvj49pg709#b3-cvj49pg709" style="color: blue; text-decoration: underline; text-underline: single;">3</a>) described a feline case of uterine adenomyosis, with emphasis on the histological appearance and diagnosis of the disease. As in this case, evaluation found a grossly enlarged uterus, endometrial invasion of the myometrium, and purulent debris. Interestingly, the ovaries of both cats had multiple follicles, corpora lutea, and cysts. Tamada et al (<a href="http://www.ncbi.nlm.nih.gov/pubmed/15943119" style="color: blue; text-decoration: underline; text-underline: single;">10</a>) described a case where adenomyosis and cystic pyometra co-occurred in a Shiba Inu bitch, and a case of adenomyosis diagnosed following uterine torsion has also been described where the dogs showed clinical signs (<a href="http://www.ncbi.nlm.nih.gov/pubmed/11518423" style="color: blue; text-decoration: underline; text-underline: single;">11</a>). In both these cases, the clinical signs were assumed to be due to the co-occurring lesions, not adenomyosis. In this respect, this case is unusual in that adenomyosis alone caused clinical signs severe enough to warrant exploration and ovariohysterectomy.</div>
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Adenomyosis is an important differential diagnosis for uterine disease in both domestic and zoo animals. Uterine adenomyosis may be misdiagnosed clinically, and suggestive lesions merit full light microscopic examination. The potential link of exogenous hormone therapy and adenomyosis deserves further investigation in both veterinary and human medicine.</div>
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Acknowledgments</div>
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The author thanks Dr. Peter Gilbert for his assistance in attending to this case, and Dr. Trent Bollinger, Dr. Beverly Kidney, and Dr. Bruce Grahn for their assistance formulating the manuscript. CVJ</div>
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Footnotes</div>
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Dr. Bulman-Fleming will receive 50 free reprints of her article, courtesy of The Canadian Veterinary Journal.</div>
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2. Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update: Eur Soc Hum Reprod Embryol. 1998;4:312–322.</div>
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3. Pack FD. Feline uterine adenomyosis: A case report. Feline Pract. 1980;10:45–47.</div>
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4. Bergholt T, Eriksen L, Jacobsen M, Hertz JB. Prevalence and risk factors of adenomyosis at hysterectomy. Hum Reprod Update: Eur Soc Hum Reprod Embryol. 2001;16:2418–2421.</div>
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5. Parrott E, Butterworth M, Green A, White INH, Greaves P. Adenomyosis — A result of disordered stromal differentiation. Am J Pathol. 2001;159:623–630. [<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850567/" style="color: blue; text-decoration: underline; text-underline: single;">PMC free article</a>] [<a href="http://www.ncbi.nlm.nih.gov/pubmed/11485920" style="color: blue; text-decoration: underline; text-underline: single;" target="pmc_ext">PubMed</a>]</div>
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6. Munson L, Gardner IA, Mason RJ, Chassy LM, Seal US. Endometrial hyperplasia and mineralization in zoo felids treated with melegestrol acetate contraceptives. Vet Pathol. 2002;39:419–427. [<a href="http://www.ncbi.nlm.nih.gov/pubmed/12126144" style="color: blue; text-decoration: underline; text-underline: single;" target="pmc_ext">PubMed</a>]</div>
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7. Wood C. Surgical and medical treatment of adenomyosis. Hum Reprod Update: Eur Soc Hum Reprod Embryol. 1998;4:323–336.</div>
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8. Plumb DC. Plumb’s Veterinary Drug Handbook. 5. Stockholm, Wisconsin: Blackwell Publ; 2005. </div>
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9. Romagnoli S. Clinical use of hormones in the control of reproduction in bitches and queens. World Small Anim Vet Cong Proc 2002. [Last accessed 17/01/07]; Veterinary Information Network [database on the Internet]; Davis: c1991–2007 (Updated 2007)</div>
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10. Tamada H, Kawate N, Inaba T, et al. Adenomyosis with severe inflammation in the uterine cervix in a dog. Can Vet J. 2005;46:333–334. [<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1082876/" style="color: blue; text-decoration: underline; text-underline: single;">PMC free article</a>] [<a href="http://www.ncbi.nlm.nih.gov/pubmed/15943119" style="color: blue; text-decoration: underline; text-underline: single;" target="pmc_ext">PubMed</a>]</div>
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11. Stocklin-Gautschi NM, Guscetti F, Reichler IM, Geissbuhler U, Brown SA, Arnold S. Identification of focal adenomyosis as a uterine lesion in 2 dogs. J Small Anim Pract. 1001;42:413–416. [<a href="http://www.ncbi.nlm.nih.gov/pubmed/11518423" style="color: blue; text-decoration: underline; text-underline: single;" target="pmc_ext">PubMed</a>]</div>
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Articles from The Canadian Veterinary Journal are provided here courtesy of <br />
Canadian Veterinary Medical Association </div>
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<b><span style="font-size: 16pt;">3)<a href="http://www.ncbi.nlm.nih.gov/pubmed/17392005" style="color: blue; text-decoration: underline; text-underline: single;">Feline diabetes mellitus in the UK: the prevalence within an insured cat population and a questionnaire-based putative risk factor analysis.</a></span></b></div>
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McCann TM, Simpson KE, Shaw DJ, Butt JA, Gunn-Moore DA.</div>
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J Feline Med Surg. 2007 Aug;9(4):289-99. Epub 2007 Mar 27.</div>
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PMID: 17392005 [PubMed - indexed for MEDLINE] </div>
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<a href="http://www.ncbi.nlm.nih.gov/pubmed/17392005##" style="color: blue; text-decoration: underline; text-underline: single;" title="Journal of feline medicine and surgery.">J Feline Med Surg.</a> 2007 Aug;9(4):289-99. Epub 2007 Mar 27.</div>
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Division of Veterinary Clinical Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh Hospital for Small Animals, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK.</div>
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Prevalence and risk factors for the development of diabetes mellitus (DM) in cats in the United Kingdom have not previously been reported. The prevalence of DM was evaluated in a large insured population and was found to be 1 in 230 cats. In this insured cat population Burmese cats were 3.7 times more likely to develop DM than non-pedigree cats. A convenience-sampling questionnaire-based study was used in order to identify putative risk factors for the development of DM. The univariate risk factor analysis identified being male, neutered, inactive, weighing >or=5 kg and having a history of corticosteroid treatment as significant risk factors for the development of DM in these cats. In addition, male cats treated with megestrol acetate had a significantly increased risk of developing DM compared to females. In contrast, there was no difference in DM occurrence between male and female Burmese cats. A multivariate classification tree-based model on the questionnaire data looking for interactions between risk factors, identified gender as the most important overall risk factor for the development of DM with low physical activity being the next most important risk factor for female cats and breed the next most important for male cats.</div>
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PMID:</div>
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17392005</div>
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<b><span style="font-size: 16pt;">4)<a href="http://www.ncbi.nlm.nih.gov/pubmed/16626799" style="color: blue; text-decoration: underline; text-underline: single;">Contraception in felids.</a></span></b></div>
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Munson L.</div>
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Theriogenology. 2006 Jul 1;66(1):126-34. Epub 2006 Apr 19. Review.</div>
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16626799</div>
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<a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Munson%20L%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Munson L</a>.</div>
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Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, 1 Shields Ave., Davis, CA 95616, USA. lmunson@ucdavis.edu</div>
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Contraceptives are used for reversible reproductive control in genetically valuable wild felids, as permanent reproductive control in generic wild felids, and as an economically practicable means to control feral cats. The progestin contraceptives, megestrol acetate, melengesterol acetate, medroxyprogesterone acetate, and levonorgestrol (administered orally, in implants, or as depot injections), are effective in preventing pregnancy. However, long-term use is associated with endometrial hyperplasia, endometrial cancer, and mammary cancer. Gonadotropin releasing hormone analogs or luteinizing hormone vaccines that achieve contraception by suppressing ovarian or testicular function, do not have the adverse health effects of progestins. However, reliable reversibility has not been demonstrated, and male secondary sex characteristics may be suppressed. Bisdiamines also inhibit spermatogenesis and lower circulating testosterone concentrations in treated male cats. Porcine zona pellucida vaccines are ineffective contraceptives in felids and may cause serious health problems when combined with some adjuvants. Because of the limited availability of non-progestin contraceptives and side effects associated with some agents, widespread application of contraception to felids has been curtailed. More non-steroidal methods of contraception should be tested in the future to provide alternatives for controlling reproduction in felids. Furthermore, all empirical information on contraceptive safety and efficacy should be assembled in a database to provide the knowledge needed by veterinarians and managers to determine benefits/risks of currently available contraceptives in felids, both domestic and wild.</div>
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PMID: 16626799</div>
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<b><span style="font-size: 16pt;">5)<a href="http://www.ncbi.nlm.nih.gov/pubmed/12677692" style="color: blue; text-decoration: underline; text-underline: single;">Mammary fibroadenomatous hyperplasia in a young cat attributed to treatment with megestrol acetate.</a></span></b></div>
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MacDougall LD.</div>
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Can Vet J. 2003 Mar;44(3):227-9.</div>
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PMID:12677692</div>
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Can Vet J. 2003 March; 44(3): 227–229. <span style="color: #333333;">PMCID: PMC340082</span></div>
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© <a href="http://www.ncbi.nlm.nih.gov/pmc/about/copyright.html" style="color: blue; text-decoration: underline; text-underline: single;">Copyright</a> and/or publishing rights held by the Canadian Veterinary Medical Association</div>
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Lori D. MacDougall</div>
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Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.</div>
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<shape alt="Small right arrow pointing to:" coordsize="21600,21600" id="_x0000_s1034" style="height: 6pt; width: 3pt;" type="#_x0000_t75"><imagedata o:href="http://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/rt-arrow.gif" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image003.gif"></imagedata></shape>This article has been <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/citedby/" style="color: blue; text-decoration: underline; text-underline: single;">cited by</a> other articles in PMC.</div>
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A male, neutered cat was presented for lethargy, reluctance to walk, and mammary enlargement after recent treatment with megestrol acetate. Mammary fibroadenomatous hyperplasia was diagnosed on the basis of history, clinical signs, and histopathological findings. Pathogenesis, clinical signs, and treatment options for mammary fibroadenomatous hyperplasia attributed to megestrol acetate treatment are discussed.</div>
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A 1.5-year-old, neutered male, domestic shorthair was presented to the Strathmore Veterinary Clinic, Strathmore, Alberta for a pruritic, hemorrhagic dermatopathy of the chin region. A tentative diagnosis of a superficial pyoderma was made and the cat was discharged with the following therapies: topical cleansing; oral orbifloxacin (Orbax; Schering-Plough, Pointe Claire, Quebec), 2.2 mg/kg bodyweight (BW), q24h for 14 d; and oral prednisone (generic), 1 mg/kg BW, q24h for 4 d.</div>
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The cat was presented to the clinic again, approximately 1 mo later. The lesion on the chin remained pruritic, and 2 additional similar lesions were on the ventral aspect of the neck and mandible. At this time, the owners declined to have the skin biopsied. Eosinophil-granuloma complex was suspected and methylprednisolone acetate (Depo-Medrol; Upjohn, Mississauga, Ontario), 4 mg/kg BW, SC, was administered. A hypoallergenic food trial was commenced.</div>
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The cat was presented to the clinic again, 38 d after initial presentation, with continuing pruritus. The therapeutic regime was modified at this time to include oral megestrol acetate (Ovaban; Schering-Plough), 1 mg/kg BW, q24h for 5 d, and then 0.5 mg/kg BW, PO twice weekly for 21 d. This prescription was refilled 33 d after initiation of the oral megestrol acetate treatment, so that the cat received 1 mg/kg BW, PO, q24h for 2 d, followed by 0.5 mg/kg BW, PO, q24h for 16 d.</div>
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A recheck appointment was scheduled for 7 d after the prescription had been completed, that is, 58 d after initiation of megestrol acetate treatment. The cat, at this time, demonstrated acute mammary enlargement and reluctance to walk. Findings on physical examination were unremarkable, except for the chin and mammary glands. All 6 mammary glands were asymmetrically enlarged, with diameters ranging from 1.5 cm to 5 cm. The most severely affected gland was the right inguinal, which was hyperemic, warm, and edematous near the teat. Thoracic radiographs, taken to screen for possible pulmonary metastases, were within normal limits. A complete blood cell (CBC) count and chemistry panel were performed on a blood analysis machine, (IDEXX VetLab; IDEXX Laboratories, Westbrook, Maine USA), and the results were within normal limits. A urinalysis was not performed.</div>
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Differential diagnoses included mammary adenocarcinoma or carcinoma, mammary adenoma, or mammary sarcoma. Due to the recent history of progestin administration and the involvement of more than 1 gland, mammary hyperplasia was the most likely diagnosis.</div>
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A simple mastectomy of the right inguinal mammary gland and an excisional biopsy of the right inguinal lymph node were performed under general anesthesia. These tissues were submitted to the Western College of Veterinary Medicine for histological examination. The final histological diagnosis of the right inguinal gland was mammary fibroadenomatous hyperplasia (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/figure/f1-20/" style="color: blue; text-decoration: underline; text-underline: single;">Figure 1</a>). The right inguinal gland also had neutrophilic infiltrates beneath the ulcerated area, suggesting a superficial mastitis. The right inguinal lymph node had no histological lesions.</div>
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<span class="MsoHyperlink"><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/figure/f1-20/" style="color: blue; text-decoration: underline; text-underline: single;" target="figure"><shape alt="figure 20FF1" coordsize="21600,21600" id="_x0000_s1033" o:button="t" style="height: 48pt; width: 75pt;" type="#_x0000_t75"><imagedata o:href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/bin/20FF1.gif" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image004.gif"></imagedata></shape></a></span></div>
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Figure. 1. Mammary fibroadenomatour hyperplasia in a 1 and 1.5 year old male neutered cat after treatment with standard dosages of megestrol acetate (progesterone analogue). (A) Mammary adenomatous hyperplasia of lobular ducts. (B) Fibrous hyperplasia<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/figure/f1-20/" style="color: blue; text-decoration: underline; text-underline: single;"> (more ...)</a></div>
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Recheck examinations were performed 10 d and 15 d after surgery, that is, 68 d and 73 d after initiation of megestrol acetate treatment. Abdominal and thoracic mammary glands had regressed slightly, but the left inguinal mammary gland had enlarged slightly.</div>
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The cat was presented to the clinic 7 d later for inappetance (80 d after initiation of megestrol acetate treatment). On physical examination, the cat was mildly febrile (temperature 39.9°C; normal 38.5°C to 39.5°C) and estimated to be 5% dyhydrated. A small, ulcerated skin lesion, similar to previous lesions, was noted on the ventral chin. The left inguinal mammary gland was ulcerated, swollen, warm, painful, and asymmetrically enlarged to 4 cm in diameter. A CBC count showed a mild leukocytosis (18.9 × 109/L; normal, 6.0 to 16.9 × 109/L) and mild neutrophilia (15.5 × 109/L; normal, 2.8 to 10.5 × 109/L). A presumptive diagnosis of superficial mastitis (complicating the underlying mammary hyperplasia) was made. The cat received trimethoprim-sulfadiazine (Tribrissen; Schering Plough), 35 mg/kg BW, SC, q24h for 3 d, meloxicam (Metacam Injectable; Boehringer Ingelheim Vetmedica, Burlington, Ontario), 0.02 mg/kg BW, SC, q24h, and lactated Ringer's solution, 60 to 120 mL, SC, q24 h for the next 3 d. During this time, the cat's temperature returned to normal (38.5°C). The therapeutic plan was to return the cat to the owners once the cat was eating sufficiently on his own, to continue antibiotic treatment for 10 d, and to biopsy the skin lesions after the antibiotic course had been completed.</div>
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The owners did not wish to pursue further diagnostic tests. When the cat's skin lesions returned, they elected for euthanasia. A necropsy was not performed.</div>
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Feline mammary fibroadenomatous hyperplasia, also known as feline mammary hypertrophy or fibroepithelial hyperplasia, is a nonneoplastic, progesterone-induced condition (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r1-20#r1-20" style="color: blue; text-decoration: underline; text-underline: single;">1</a>). Typical signalments include young cycling cats, pregnant or pseudopregnant female cats, or older neutered male or female cats given exogenous progestins (<a href="http://www.ncbi.nlm.nih.gov/pubmed/2711568" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). Cats present with mammary enlargement, involving one or more glands. The enlargement is due to rapid proliferation of mammary duct epithelium and stroma. Hyperplastic mammary tissue may undergo spontaneous regression; may require ovariohysterectomy, if secondary, to elevated estrogen levels; or may regress once progesterone levels decline. Mammary hyperplasia must be distinguished by microscopic examination from mammary neoplasia, as the latter has a poor prognosis. Mammary neoplasms in the cat often grow rapidly, are firm and ulcerated, and metastasize early to local lymph nodes and lungs (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r3-20#r3-20" style="color: blue; text-decoration: underline; text-underline: single;">3</a>).</div>
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Megestrol acetate is a progestagen. In veterinary medicine, it has been used to treat pseudopregnancy in dogs; to suppress or delay estrus in cats and dogs; to treat behavior-related conditions in cats; to treat feline eosinophilic and proliferative keratopathies; and, less commonly, as an appetite stimulant (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r4-20#r4-20" style="color: blue; text-decoration: underline; text-underline: single;">4</a>,<a href="http://www.ncbi.nlm.nih.gov/pubmed/11316295" style="color: blue; text-decoration: underline; text-underline: single;">5</a>). However, it has not been approved for use in the cat. Side effects noted in cats are as follows: iatrogenic adrenocortical suppression, transient diabetes mellitus, hepatotoxicity, cystic endometrial hyperplasia, and mammary hypertrophy or neoplasia (<a href="http://www.ncbi.nlm.nih.gov/pubmed/7198885" style="color: blue; text-decoration: underline; text-underline: single;">6</a>). There is evidence that megestrol acetate has a glucocorticoid-like activity. Its use may result in suppression of the adrenocortical axis for 2 to 4 wk after treatment, 5 mg/kg BW/cat, q24h, 14d, and in hyperinsulinemia (<a href="http://www.ncbi.nlm.nih.gov/pubmed/8191007" style="color: blue; text-decoration: underline; text-underline: single;">7</a>). Therefore, discontinuing megestrol acetate therapy abruptly is not recommended (<a href="http://www.ncbi.nlm.nih.gov/pubmed/8191007" style="color: blue; text-decoration: underline; text-underline: single;">7</a>).</div>
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Fibroadenomatous mammary hyperplasia is a relatively uncommon sequela to the administration of megestrol acetate (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r8-20#r8-20" style="color: blue; text-decoration: underline; text-underline: single;">8</a>). This therapy was found to be clearly associated with mammary fibroepithelial hyperplasia in predominantly older (average age 8.1 y) neutered male or female cats (<a href="http://www.ncbi.nlm.nih.gov/pubmed/2711568" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). In the case reported here, the affected cat was 1.5 y old; however, the youngest cat reported in another study was 11 mo old (<a href="http://www.ncbi.nlm.nih.gov/pubmed/11316295" style="color: blue; text-decoration: underline; text-underline: single;">5</a>). Secondary mastitis, ulceration, or both may be observed with this condition, as was confirmed in this case on histopathologic examination.</div>
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Maximal mammary development seems to require a synergism between pituitary hormones and ovarian steroids (<a href="http://www.ncbi.nlm.nih.gov/pubmed/2711568" style="color: blue; text-decoration: underline; text-underline: single;">2</a>). Mammary duct epithelium and stromal proliferation (benign) is thought to be progesterone dependent (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r8-20#r8-20" style="color: blue; text-decoration: underline; text-underline: single;">8</a>). Steroid receptors within mammary tissue recognize progesterone and estrogen, and through these receptors hormonal action is medicated.</div>
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Immunohistochemistry techniques have been used to identify and distinguish estrogen and progesterone hormone receptors. In cases that were studies, progesterone receptors were identified in tissues of all cases of mammary hypertrophy, while estrogen receptors were recognized in only 50% of tissues (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r1-20#r1-20" style="color: blue; text-decoration: underline; text-underline: single;">1</a>). It is hypothesized that “the interaction of progesterone and synthetic progestins with progesterone receptors stimulates the local production of growth hormone, which would act on a potential autocrine/paracrine stimulatory loop to induce proliferation of mammary epithelial and stromal cells” (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r1-20#r1-20" style="color: blue; text-decoration: underline; text-underline: single;">1</a>).</div>
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In this case, one could speculate that the exogenous methylprednisolone acetate given 3 d before initiation of megestrol acetate may have allowed synergistic action between glucocorticoids and progestins, encouraging maximal mammary development. Further studies showing the interaction between these 2 hormones may be indicated.</div>
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Typically, the treatment for mammary hyperplasia in cats was ovariohysterectomy (if intact), mastectomy, or cessation of progestin therapy and allowing time for mammary regression. More recently, a progesterone-antagonist has been used successfully to treat hyperplasia in intact or neutered cats by eliminating the source of progestin (<a href="http://www.ncbi.nlm.nih.gov/pubmed/11316295" style="color: blue; text-decoration: underline; text-underline: single;">5</a>). Seven cats affected with mammary hyperplasia were treated with aglepristone (Alizine; Aventis, Strasbourg, France), 10 mg/kg BW, SC, q24h for 4 to 5 d. Five days after the initial treatment, reduction in the size of the mammary glands, as well as change in consistency of affected glands (from rigid to soft), was observed. Corresponding biopsies taken 7 d after the first treatment showed collapse of the glandular duct lumens and reduction in the number of epithelial cells. It was reported to take 3 to 4 wk for complete involution of the glands. One of the 7 cats studied had recurrence of mammary hyperplasia 13 d after initial reduction in mammary gland size (16 d after initial treatment with aglepristone). No side effects were observed in any of the 7 cats treated with aglepristone.</div>
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In this case, progesterone blood levels were not measured, and tests for progesterone receptors on fixed mammary tissue were not performed. Therefore, the diagnosis of mammary hyperplasia due to megestrol acetate therapy is presumptive. However, the “apparent influence of a progestagen, whether present as exogenous therapy in the male or female or as endogenous steroid of ovarian origin, has been demonstrated directly and indirectly in cats with mammary hypertrophy” (<a href="http://www.ncbi.nlm.nih.gov/pubmed/7198885" style="color: blue; text-decoration: underline; text-underline: single;">6</a>). Aglepristone may have been a viable treatment option for this cat (if commercially available) to reduce the size of all affected mammary glands.</div>
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It should be noted that the dose of megestrol acetate used was within the standard dosing regimen (never greater than 0.5 to 1 mg/kg BW, q24h) (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r10-20#r10-20" style="color: blue; text-decoration: underline; text-underline: single;">10</a>). However, the dose or duration of therapy with exogenous progestins cannot be used as a predictor for mammary hyperplasia (<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC340082/#r8-20#r8-20" style="color: blue; text-decoration: underline; text-underline: single;">8</a>). Veterinarians should be aware of the potential, yet uncommon, side effects discussed above. CVJ</div>
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Footnotes</div>
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Acknowledgments </div>
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The author thanks Drs. P. Dowling, K. Mealey, M. Johnson, B. Fransson, and E. O'Toole for their advice. CVJ</div>
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Dr. MacDougall's current address is Western Veterinary Specialist Centre, 1635–17th Avenue Southwest, Calgary, Alberta T2T 0E5.</div>
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Address all correspondence to Dr. MacDougall.</div>
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Reprints will not be available from the author.</div>
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References</div>
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10. Plumb DC. Veterinary Drug Handbook, 3rd ed. White Bear Lake: Pharma Vet Publ, 1999:398–401.</div>
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<a href="http://www.ncbi.nlm.nih.gov/pubmed/8191007##" style="color: blue; text-decoration: underline; text-underline: single;" title="Research in veterinary science.">Res Vet Sci.</a> 1994 Mar;56(2):175-8.</div>
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<b><span style="color: blue; font-size: 16pt;">6)Effects of proligestone and megestrol on plasma adrenocorticotrophic hormone, insulin and insulin-like growth factor-1 concentrations in cats.</span></b></div>
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<a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Church%20DB%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Church DB</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Watson%20AD%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Watson AD</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Emslie%20DR%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Emslie DR</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Middleton%20DJ%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Middleton DJ</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Tan%20K%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Tan K</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Wong%20D%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Wong D</a>.</div>
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Source</div>
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Department of Veterinary Clinical Sciences, University of Sydney, New South Wales, Australia.</div>
<div class="MsoNormal">
Abstract</div>
<div class="MsoNormal">
This paper reports changes in adrenocorticotrophic hormone (ACTH), insulin and insulin-like growth factor-1 (IGF-1) concentrations in cats from a previously published study. The cats were given oral megestrol acetate (MA, 5 mg once daily for 14 days), subcutaneous proligestone (PRG, 100 mg on two occasions one week apart) or subcutaneous saline (1 ml as for PRG). In the cats given saline (n = 6), basal ACTH, insulin and IGF-1 did not change significantly throughout the following seven weeks. The cats given MA (n = 7) developed significant suppression of plasma ACTH concentrations and hyperinsulinaemia during treatment and for two to four weeks after MA dosage ceased. In the cats given PRG (n = 7), plasma ACTH concentrations were not significantly altered although three cats had markedly suppressed values for some time after PRG treatment had ceased. Serum insulin concentrations were not significantly altered in the PRG-treated cats. The results suggest PRG may be a preferable alternative to MA in some situations.</div>
<div class="MsoNormal">
PMID:</div>
<div class="MsoNormal">
8191007</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">7)<a href="http://www.ncbi.nlm.nih.gov/pubmed/8407484" style="color: blue; text-decoration: underline; text-underline: single;">Effectiveness of buspirone on urine spraying and inappropriate urination in cats.</a></span></b></div>
<div class="MsoNormal">
Hart BL, Eckstein RA, Powell KL, Dodman NH.</div>
<div class="MsoNormal">
J Am Vet Med Assoc. 1993 Jul 15;203(2):254-8.</div>
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PMID:</div>
<div class="MsoNormal">
8407484</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Source</div>
<div class="MsoNormal">
Department of Physiological Sciences, University of California, Davis 95616.</div>
<div class="MsoNormal">
Abstract</div>
<div class="MsoNormal">
The most frequent type of behavior problem in cats for which veterinary consultation is sought is problem urination. Urine spraying and urine marking have been treated by use of long-acting progestins and diazepam, a benzodiazepine antianxiety drug. Effectiveness of the nonbenzodiazepine antianxiety drug, buspirone, in suppressing urine spraying and marking in 47 male and 15 female cats was evaluated. The effect of the drug in correcting inappropriate urination in 9 cats also was evaluated. Buspirone resulted in a favorable response (> 75% reduction) in 55% of cats treated for urine spraying or marking. There was no sex difference in effectiveness of the treatment, but cats from single-cat households responded favorably significantly (P < 0.001) less frequently than those from multiple-cat households. The 55% response rate was within the range of treatment effectiveness that has been reported for diazepam, and was greater than that reported for progestin. In contrast to diazepam, with which over 90% of treated cats resumed spraying or marking when the drug was gradually discontinued, only half of the cats treated with buspirone resumed spraying when the drug was discontinued after 2 months of treatment (P < 0.001). This difference between diazepam and buspirone in resumption of urine spraying was attributed to diazepam's induction of physiologic and behavioral dependency, not found with buspirone. Cats that resumed spraying were placed on long-term treatment ranging from 6 to 18 months. Buspirone also did not cause the adverse effects of sedation and ataxia, which commonly are seen with diazepam treatment. In cats treated for inappropriate urination, 56% returned to normal litter box usage.(ABSTRACT TRUNCATED AT 250 WORDS)</div>
<div class="MsoNormal">
PMID:</div>
<div class="MsoNormal">
8407484</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
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<br /></div>
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<br /></div>
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<b><span style="font-size: 16pt;">8)<a href="http://www.ncbi.nlm.nih.gov/pubmed/8229923" style="color: blue; text-decoration: underline; text-underline: single;">Regulation of progesterone during pregnancy in the cat: studies on the roles of corpora lutea, placenta and prolactin secretion.</a></span></b></div>
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Verstegen JP, Onclin K, Silva LD, Wouters-Ballman P, Delahaut P, Ectors F.</div>
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J Reprod Fertil Suppl. 1993;47:165-73.</div>
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PMID:</div>
<div class="MsoNormal">
8229923</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Abstract</div>
<div class="MsoNormal">
The regulation of progesterone secretion and release by the corpus luteum and/or by the placenta in cats during pregnancy has been poorly studied and the relative roles of the corpus luteum and the placenta in the release of progesterone into the plasma is not well defined. It is generally assumed that after 40-45 days of pregnancy, circulating progesterone is mainly produced by the placenta and that after 45-50 days the corpus luteum is no longer necessary to maintain pregnancy, even if remnants of corpora lutea are detected in the ovaries during the following interoestrous period. In this study, the relative roles of the placenta and ovary in progesterone production after 30 days of pregnancy have been analysed in an attempt to define the role of progesterone in pregnant cats. Different experiments involved (1) analysis of the effects of an ovariectomy performed at 30 days of pregnancy, and of megestrol acetate supplementation on plasma progesterone during the second half of pregnancy, (2) analysis of the effects of an ovariectomy performed at 45 days on plasma progesterone production and on pregnancy and (3) analysis of the effects of an antiprolactin agent (cabergoline) at days 30 and 40 of pregnancy on progesterone secretion and pregnancy. These results were all compared with the normal plasma progesterone profiles during (a) pseudopregnancy and (b) pregnancy.(ABSTRACT TRUNCATED AT 250 WORDS)</div>
<div class="MsoNormal">
PMID:</div>
<div class="MsoNormal">
8229923</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">9)<a href="http://www.ncbi.nlm.nih.gov/pubmed/1533207" style="color: blue; text-decoration: underline; text-underline: single;">Comparison of diazepam with progestin for effectiveness in suppression of urine spraying behavior in cats.</a></span></b></div>
<div class="MsoNormal">
Cooper L, Hart BL.</div>
<div class="MsoNormal">
J Am Vet Med Assoc. 1992 Mar 15;200(6):797-801.</div>
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<br /></div>
<div class="MsoNormal">
Department of Physiological Sciences, School of Veterinary Medicine, University of California, Davis 95616.</div>
<div class="MsoNormal">
Abstract</div>
<div class="MsoNormal">
The most common treatment for urine spraying and marking in cats has been administration of long-acting progestins. Treatment with diazepam has recently been gaining favor, particularly because of reported adverse effects of progestins. Results of a clinical trial involving 20 cats indicated that diazepam was effective in eliminating or markedly reducing spraying in 11 (55%) of them. However, most cats required continuous treatment, or at least intermittent treatment, when spraying recurred. The physiologic and behavioral dependency of cats on diazepam, which presumably develops over the course of administration, may contribute to the tendency for spraying to recur once diazepam treatment is discontinued. Using data from previously published findings on progestin administration, plus additional cases, it was documented that a significantly (P less than 0.05) higher percentage of males than females responded favorably. Although the number of cases was not sufficient for a statistical comparison of diazepam vs progestin treatment with regard to male vs female, possible gender difference in the effectiveness of diazepam was not indicated.</div>
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<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">10) <a href="http://www.ncbi.nlm.nih.gov/pubmed/2045343" style="color: blue; text-decoration: underline; text-underline: single;">Current and proposed methods for contraception and termination of pregnancy in dogs and cats.</a></span></b></div>
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Concannon PW, Meyers-Wallen VN.</div>
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Department of Physiology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.</div>
<div class="MsoNormal">
J Am Vet Med Assoc. 1991 Apr 1;198(7):1214-25. </div>
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<br /></div>
<div class="MsoNormal">
No abstract available. </div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">11)<a href="http://www.ncbi.nlm.nih.gov/pubmed/2063167" style="color: blue; text-decoration: underline; text-underline: single;">[Chronic eosinophilic keratitis in the cat].</a></span></b></div>
<div class="MsoNormal">
Spiess BM, Leber A, von Beust BR, Hauser B.</div>
<div class="MsoNormal">
Schweiz Arch Tierheilkd. 1991;133(3):113-8. German. </div>
<div class="MsoNormal">
PMID:</div>
<div class="MsoNormal">
2063167</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
[Article in German]</div>
<div class="MsoNormal">
<a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Spiess%20BM%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Spiess BM</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Leber%20A%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Leber A</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22von%20Beust%20BR%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">von Beust BR</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Hauser%20B%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Hauser B</a>.</div>
<div class="MsoNormal">
Source</div>
<div class="MsoNormal">
Veterinär-Chirurgische Klinik, Universität Zürich.</div>
<div class="MsoNormal">
Abstract</div>
<div class="MsoNormal">
A special form of keratitis in the cat is described on the basis of 8 clinical cases. The disease has been known in the United States and the United Kingdom for some time, however, it has, to our knowledge, never been described in Switzerland. This keratitis is characterized by chronicity and infiltration of the cornea by mast cells and eosinophils. It is usually an unilateral and painless condition. We describe the clinical features and diagnostic examinations of the disease. Cytology of a corneal scraping is usually diagnostic. As in the cases described in the literature the cats were successfully treated with oral megestrol acetate. The aetiology of the disease is unknown.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">12)<a href="http://www.ncbi.nlm.nih.gov/pubmed/2300703" style="color: blue; text-decoration: underline; text-underline: single;">Effect of megestrol acetate on the endometrium of the prepubertally ovariectomised kitten.</a></span></b></div>
<div class="MsoNormal">
Bellenger CR, Chen JC.</div>
<div class="MsoNormal">
Res Vet Sci. 1990 Jan;48(1):112-8.</div>
<div class="MsoNormal">
PMID:</div>
<div class="MsoNormal">
2300703</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Bellenger%20CR%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Bellenger CR</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Chen%20JC%22%5BAuthor%5D" style="color: blue; text-decoration: underline; text-underline: single;">Chen JC</a>.</div>
<div class="MsoNormal">
Source</div>
<div class="MsoNormal">
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales, Australia.</div>
<div class="MsoNormal">
Abstract</div>
<div class="MsoNormal">
Five prepubertally ovariectomised kittens served as controls. Ten prepubertally ovariectomised kittens were given megestrol acetate (MA) orally at the rate of either 5 or 15 mg twice weekly for 12 to 13 weeks. The uterine horns of treated cats increased in length and diameter. The endometrium became deeply folded with marked hypertrophy of glandular epithelium and production of glycogen by the glandular cells. One cat developed pyometra. Once weekly administration of 2.5 mg MA for a further 12 weeks maintained the hypertrophic changes. The proliferated endometrium regressed considerably but not completely after 12 weeks without MA administration. In two other kittens 2.5 mg MA once weekly for six weeks was sufficient to induce similar changes. MA is a very potent progestational agent in cats, even if they have been ovariectomised prepubertally.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">13) <a href="http://www.ncbi.nlm.nih.gov/pubmed/2556766" style="color: blue; text-decoration: underline; text-underline: single;">Comparative effects of proligestone and megestrol acetate on basal plasma glucose concentrations and cortisol responses to exogenous adrenocorticotrophic hormone in cats.</a></span></b></div>
<div class="MsoNormal">
Watson AD, Church DB, Emslie DR, Middleton DJ.</div>
<div class="MsoNormal">
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales, Australia.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Res Vet Sci. 1989 Nov;47(3):374-6.</div>
<div class="MsoNormal">
PMID:</div>
<div class="MsoNormal">
2556766</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Cats were given megestrol acetate (MA, 5 mg once daily for 14 days), subcutaneous proligestone (PRG, 100 mg on two occasions one week apart) or subcutaneous saline (1 ml as for PRG). In cats given saline (n = 6) basal cortical concentrations, cortisol concentrations after adrenocorticotrophic hormone (ACTH) administration and fasting blood glucose concentrations did not change significantly during the following seven weeks. Cats given MA (n = 7) developed suppression of basal and ACTH-stimulated cortisol concentrations and fasting hyperglycaemia during treatment. Effects on cortisol persisted for two weeks after MA dosage ceased. In cats given PRG (n = 7), basal cortisol concentrations were reduced overall, but only three cats had persistently suppressed post-ACTH cortisol concentrations. Adrenal suppression continued for 14 weeks in one of these and for at least 22 weeks in two cats. Fasting blood glucose concentrations were unchanged in PRG-treated cats.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="color: blue; font-size: 16pt;">14)Retrospective Study</span></b></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;"><a href="http://www.ncbi.nlm.nih.gov/pubmed/2711568" style="color: blue; text-decoration: underline; text-underline: single;"><span style="text-decoration: none;">Morphologic changes in the mammary gland of megestrol acetate-treated and untreated cats: a retrospective study.</span></a></span></b></div>
<div class="MsoNormal">
Hayden DW, Barnes DM, Johnson KH.</div>
<div class="MsoNormal">
Vet Pathol. 1989 Mar;26(2):104-13.</div>
<div class="MsoNormal">
PMID: 2711568</div>
<div class="MsoNormal">
<span style="color: blue; font-size: 11pt;">http://vet.sagepub.com/content/26/2/104</span></div>
<div class="MsoNormal">
<span style="color: black; font-size: 11pt;">The online version of this article can be found at:</span></div>
<div class="MsoNormal">
<span style="color: black; font-size: 11pt;">DOI: 10.1177/030098588902600202</span></div>
<div class="MsoNormal">
Vet Pathol. 1989 Mar;26(2):104-13.</div>
<div class="MsoNormal">
PMID: 2711568</div>
<div class="MsoNormal">
<span style="color: blue; font-size: 11pt;">http://vet.sagepub.com/content/26/2/104</span></div>
<div class="MsoNormal">
<span style="color: black; font-size: 11pt;">The online version of this article can be found at:</span></div>
<div class="MsoNormal">
<span style="color: black; font-size: 11pt;">DOI: 10.1177/030098588902600202</span></div>
<div class="MsoNormal">
D. W. HAYDEND, . M. BARNESA, ND K. H. JOHNSON</div>
<div class="MsoNormal">
Department of Veterinary Pathobiology and Department of Veterinary Diagnostic Investigation,</div>
<div class="MsoNormal">
College of Veterinary Medicine, University of Minnesota, St. Paul, MN</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Abstract. Abnormal mammary gland growth is a side effect of progestin therapy in some cats. In this</div>
<div class="MsoNormal">
retrospective study, the nature and significance of morphologic changes in the mammary gland of 17 megestrol</div>
<div class="MsoNormal">
acetate (MA)-treated cats were compared to mammary lesions in 97 untreated cats. Fourteen out of 17 MAtreated</div>
<div class="MsoNormal">
cats had non-neoplastic mammary lesions including fibroepithelial hyperplasia (nine cats), lobular hyperplasia</div>
<div class="MsoNormal">
(three cats), and duct ectasia (two cats); whereas three MA-treated cats had mammary neoplasms</div>
<div class="MsoNormal">
including one adenoma and two carcinomas. Although MA has been causally linked to mammary cancer in</div>
<div class="MsoNormal">
cats, only mammary fibroepithelial hyperplasia was clearly associated with MA therapy in this study. Fibroepithelial</div>
<div class="MsoNormal">
hyperplasia occurred in older (average age 8.1 years) neutered male and female cats in the MA-treated</div>
<div class="MsoNormal">
group and in younger (average age 2.1 years) female cats in the untreated group. Morphologically, both intraductal</div>
<div class="MsoNormal">
and solid fibroepithelial growth patterns were seen. Intraductal fibroepithelial hyperplasia was further subdivided</div>
<div class="MsoNormal">
into papillary and circumferential types. An apparent greater association between MA therapy and the intraductal</div>
<div class="MsoNormal">
types of fibroepithelial hyperplasia was noted. Furthermore, it appears likely that mammary lobular hyperplasia</div>
<div class="MsoNormal">
also is linked to MA therapy. Possible mammatrophic effects of MA and other growth-promoting agents in the</div>
<div class="MsoNormal">
cat are discussed.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Megestrol acetate (MA), a 17 alpha-acetoxy-6 methylsynthetic analog of progesterone, was originally developed</div>
<div class="MsoNormal">
as an oral steroid contraceptive agent for use n women.7 This potent anti-ovulatory compound has</div>
<div class="MsoNormal">
progestational activity 25 times greater than that of progesterone.21A although approved for use in dogs to</div>
<div class="MsoNormal">
postpone estrus and alleviate false pregnancy, MA also is given to cats for a multiplicity of clinical problems</div>
<div class="MsoNormal">
including reproductive control, behavioral modification, and certain dermatologic conditions. l 7 The current</div>
<div class="MsoNormal">
popularity of progestins as therapeutic agents for cats increases the possibility of encountering undesirable</div>
<div class="MsoNormal">
side effects of these drugs. Some of the more potentially serious side effects attributed specifically to</div>
<div class="MsoNormal">
MA in the cat are: adrenal cortical suppression, glucose intolerance and overt diabetes mellitus, pyometra, and abnormal mammary growth.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Changes in mammary gland architecture previously reported with MA therapy generally fall into the categories</div>
<div class="MsoNormal">
of either mammary hypertrophy (fibroepithelial hyperplasia), or mammary carcinoma . Mammary hypertrophy is a non-neoplastic, progesterone- responsive condition characterized by rapid proliferation of mammary stroma and duct epithelium in one or more glands. Detailed clinicopathologic information about this condition can be found elsewhere. In comparison, relatively few references to mammary neoplasms or other types of mammary lesions have been documented in cats given synthetic progestins. As part of an ongoing effort to define the role of hormones in the pathogenesis of feline mammary neoplasia, we explored the spectrum of histopathologic lesions encountered in the mammary gland of 17</div>
<div class="MsoNormal">
MA-treated cats. Morphologic effects seen included fibroepithelial hyperplasia, lobular hyperplasia, duct</div>
<div class="MsoNormal">
ectasia, and mammary neoplasia. The nature and significance of these findings are discussed and compared</div>
<div class="MsoNormal">
with similar types of mammary lesions in untreated cats.</div>
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<br /></div>
<div class="MsoNormal">
Materials and Methods</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Case materials compiled for this study included formalinfixed cat mammary tissues submitted to the Veterinary</div>
<div class="MsoNormal">
Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota (from 1980 to 1986) as well as mastectomy specimens obtained at veterinary hospitals in Minneapolis and St. Paul. Criteria used for selection of the 17</div>
<div class="MsoNormal">
cats included in this study were the diagnosis of mammary lesions concomitant with a history of megestrol acetate (MA)</div>
<div class="MsoNormal">
therapy. Data on breed, age, sex, drug dosage, site of mammary lesion, evolution of lesion in relationship to drug administration, and gross appearance of the lesion were obtained from submission forms and from veterinary hospital case 104 Downloaded from vet.sagepub.com by guest on March 8, 2012 Megestrol Acetate and Mammary Morphology in Cats 105 records. In some instances, veterinarians were queried about the use of MA in cats since this information was not always provided with the history. Mammary lesions were divided into diagnostic categories based on their gross and microscopic appearance. Histologic typing of cat mammary lesions was done on 6-pm-thick hematoxylin and eosin-stained sections, following the World Health Organization publication on classification of animal mammary tumors.14</div>
<div class="MsoNormal">
Data for untreated cats were obtained by reviewing the records of 1 ,O 19 feline cases submitted to the Diagnostic</div>
<div class="MsoNormal">
Laboratory from 1984 to 1986. Ninety-seven untreated cats with mammary lesions similar to those first identified in the</div>
<div class="MsoNormal">
MA-treated group were studied and tabulated for comparison with MA-treated cats. </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Results</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
A summary of the clinicopathologic data for 17 cats with a concomitant history of abnormal mammary</div>
<div class="MsoNormal">
development and megestrol acetate (MA) therapy is given (Table 1). Fourteen of the 17 MA-treated cats</div>
<div class="MsoNormal">
had non-neoplastic alterations of mammary growth including fibroepithelial hyperplasia (nine cats), lobular</div>
<div class="MsoNormal">
hyperplasia (three cats), and duct ectasia (two cats). Three of the 17 MA-treated cats had mammary neoplasms</div>
<div class="MsoNormal">
including one adenoma and two carcinomas. Fibroepithelial hyperplasia</div>
<div class="MsoNormal">
Mammary fibroepithelial hyperplasia was subdivided into two relatively distinct morphologic types, represented</div>
<div class="MsoNormal">
by intraductal and solid growth patterns. Each pattern was about equally distributed among the nine</div>
<div class="MsoNormal">
MA-treated cats in this group. Cats with the solid growth pattern were on the average 1.3 years younger (7.5</div>
<div class="MsoNormal">
versus 8.8 years) than cats with the intraductal growth pattern. A predilection for breed or sex was not apparent</div>
<div class="MsoNormal">
for cats with either growth pattern, but six out of nine cats in this group were neutered. Seven of the</div>
<div class="MsoNormal">
nine cats with fibroepithelial hyperplasia had only one enlarged mammary gland, with the lesions most commonly</div>
<div class="MsoNormal">
(seven out of eight) confined to the two posterior pairs of glands. Although the daily dosage of MA prescribed</div>
<div class="MsoNormal">
for each cat was fairly standard (2.5-5 mg), the temporal relationship between drug dose and diagnosis</div>
<div class="MsoNormal">
was variable. Macroscopically, the intraductal type of fibroepithelial hyperplasia (four cats) projected from</div>
<div class="MsoNormal">
the wall of a fluid-filled space as a polypoid or domeshaped mass, or assumed a more annular growth about</div>
<div class="MsoNormal">
a central cavity. Abundant clear fluid with a viscous appearance usually denoted this type of lesion. Conversely,</div>
<div class="MsoNormal">
the solid type of fibroepithelial hyperplasia (five cats) was characterized by soft, friable, or firm,</div>
<div class="MsoNormal">
smooth-surfaced tissue with scant fluid. Microscopically, there was considerable overlap in</div>
<div class="MsoNormal">
the composition of the intraductal and solid types of fibroepithelial hyperplasia since both types of growth</div>
<div class="MsoNormal">
featured proliferation of mammary stromal fibroblasts and ductular epithelium. In the former instance growth</div>
<div class="MsoNormal">
of new tissue took place within the lumen of a large dilated duct, while in the latter case arborescent tubules</div>
<div class="MsoNormal">
developed within sheets of stromal cells. The intraductal form was further subdivided histologically into</div>
<div class="MsoNormal">
papillary (Fig. 1) and circumferential growth patterns (Fig. 2). The papillary pattern presented as bulbous or</div>
<div class="MsoNormal">
finger-like structures that projected intraluminally from segments of the duct wall, while the circumferential</div>
<div class="MsoNormal">
pattern was more compact and encircled the duct lumen. Differences between the papillary and circumferential</div>
<div class="MsoNormal">
intraductal growth patterns varied mainly in the extent of lesion development. Both of these growths</div>
<div class="MsoNormal">
patterns were seen in one cat (D85-14539) with multiple intraductal mammary lesions. The circumferential</div>
<div class="MsoNormal">
intraductular lesion from this cat consisted of numerous branching tubules lined by regular or dysplastic</div>
<div class="MsoNormal">
epithelium with multifocal areas of squamous metaplasia (Fig. 3). The solid type of fibroepithelial hyperplasia</div>
<div class="MsoNormal">
(Fig. 4) was similar to that previously described.' </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Lobular hyperplasia</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Lobular hyperplasia occurred in three MA-treated cats. Two were neutered (one male and one female),</div>
<div class="MsoNormal">
and one was an intact female. The first cat, a 7-yearold neutered female (FMT-78), had been given MA</div>
<div class="MsoNormal">
for about 5 weeks. Swollen mammary glands were noted about 1 month after the last treatment, and at the</div>
<div class="MsoNormal">
time of surgery some enlarged glands had already regressed. Milky fluid oozed from the cut surface of the</div>
<div class="MsoNormal">
mastectomy specimen from this cat. The second cat, a 3-year-old neutered male (FMT- 109), had been given</div>
<div class="MsoNormal">
MA for about 13 weeks. Mammary masses composed of firm lobulated tissue were found 2.5 months after</div>
<div class="MsoNormal">
the last treatment. The third cat, a 7.5-year-old female (D85- 13329), developed abnormally firm mammary</div>
<div class="MsoNormal">
tissue 6 months after MA therapy. Microscopically, expanded mammary lobules in various stages of secretory</div>
<div class="MsoNormal">
activity were found in all three cats (Fig. 5). In the male cat, a minor part of some interlobular ducts</div>
<div class="MsoNormal">
were lined by vacuolated secretory-type epithelial cells, whereas elongated basophilic secretory cells with</div>
<div class="MsoNormal">
prominent apical blebs were seen in some alveoli (Fig. 6); these changes were not observed in either female</div>
<div class="MsoNormal">
cat with lobular hyperplasia nor were they seen in prelactational mammary tissue from two normal pregnant</div>
<div class="MsoNormal">
cats studied for comparison. </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Mammary duct ectasia</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Mammary duct ectasia was found in two neutered female cats 7.5 and 9 years old, </div>
<div class="MsoNormal">
respectively. One of these cats (D84- 18686), with cystic lesions in both mammary chains,</div>
<div class="MsoNormal">
had been on MA for 5.5 years, while the other cat (D86-1761), with only one mammary lesion,</div>
<div class="MsoNormal">
had not been given MA for the last 1.5 years.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Downloaded from vet.sagepub.com by guest on March 8, 2012 106 Hayden, Barnes, and Johnson</div>
<div class="MsoNormal">
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<div class="MsoNormal">
<shape coordsize="21600,21600" id="_x0000_s1029" style="height: 431.25pt; width: 263.25pt;" type="#_x0000_t75"><imagedata o:title="F88C48DD" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image011.jpg"></imagedata></shape></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
These lesions were fluid-filled and fluctuant with some palpable nodular or thickened areas. Microscopically,</div>
<div class="MsoNormal">
the dilated ducts varied in thickness and proliferative activity. Epithelial cells were cuboidal to flattened and</div>
<div class="MsoNormal">
one to two cells thick with fronds or buds of hyperplastic epithelium reaching into the lumen at irregular</div>
<div class="MsoNormal">
intervals. Segments of some duct walls consisted of hyperplastic fibroepithelial tissue. Periductal fibrosis</div>
<div class="MsoNormal">
and small foci of lymphocytes and plasma cells also were seen.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Mammary neoplasms</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Three mammary gland neoplasms, one tubular adenoma and two carcinomas (one papillary and one</div>
<div class="MsoNormal">
tubulopapillary), were diagnosed in this study. The tubular adenoma was removed from a 5-year-old neutered</div>
<div class="MsoNormal">
female cat (D84-7386) that had been given MA for 4.5 months. It was well circumscribed and located</div>
<div class="MsoNormal">
near the base of a nipple within a zone of moderately well-developed mammary lobules. Histologically, the</div>
<div class="MsoNormal">
adenoma was characterized by numerous cross-sectional profiles of uniformly sized tubules lined by a</div>
<div class="MsoNormal">
single layer of epithelial cells and an attenuated layer of myoepithelial cells (Fig. 7). There was relatively little</div>
<div class="MsoNormal">
stroma between tubules, although there were patches of quiescent fibrous tissue with no distinct lobulation.</div>
<div class="MsoNormal">
Both cats with mammary gland cancer were neutered adults. An 1 1.5-year-old female (D85-15644) had been</div>
<div class="MsoNormal">
on MA for over 5 years. Most lesions in this cat were cystic, although some were nodular. Microscopically,</div>
<div class="MsoNormal">
a uniform population of neoplastic epithelial cells lined mammary gland ducts with expanded lumina and papillae.</div>
<div class="MsoNormal">
For the adult male cat (D84-6954) information about the dosage of MA was sketchy. Grossly, one</div>
<div class="MsoNormal">
abdominal mammary gland had been converted into firm, white tissue. Microscopically, the tumor was separated</div>
<div class="MsoNormal">
into lobules with a predominately tubular or papillary growth pattern (Fig. 8).</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Mammary lesions in MA-treated versus untreated cats </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Review of 1,019 routine feline diagnostic cases revealed 97 untreated cats with mammary </div>
<div class="MsoNormal">
lesions analgous to those identified in the MA-treated group. A comparison of the types and incidence of mammary</div>
<div class="MsoNormal">
lesions in MA-treated and untreated cats is given (Table 2). Fibroepithelial hyperplasia in MA-treated cats</div>
<div class="MsoNormal">
and carcinoma in untreated cats were clearly the predominant mammary lesions for each group. Also, the</div>
<div class="MsoNormal">
MA-treated group had a greater incidence (18% versus 3%) of mammary lobular hyperplasia. Both groups had</div>
<div class="MsoNormal">
the same proportion of cats with mammary duct ectasia.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Discussion</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Synthetic progestins are derivatives of 1 7a-hydroxyprogesterone</div>
<div class="MsoNormal">
or 19-nortetosterone.Derivatives of 1 7a-hydroxyprogesterone, like megestrol acetate (MA)</div>
<div class="MsoNormal">
and medroxyprogesterone acetate (MPA), are known to elicit a host of possible adverse side</div>
<div class="MsoNormal">
effects in the dog and cat including growth disorders of the mammary gland.3</div>
<div class="MsoNormal">
Although both MA and MPA are effective orally, the repositol form of MPA has the most </div>
<div class="MsoNormal">
prolonged effect and thus the least safety margin. Most information about the adverse effects</div>
<div class="MsoNormal">
of progestins in the cat has been gleaned from clinical data rather than from experimental</div>
<div class="MsoNormal">
studies. In this retrospective study, non-neoplastic lesions (fibroepithelial hyperplasia,</div>
<div class="MsoNormal">
lobular hyperplasia, and duct ectasia) and neoplastic lesions (tubular adenoma and </div>
<div class="MsoNormal">
mammary carcinoma) concomitant with MA therapy were found in 17 cats (Table 1).</div>
<div class="MsoNormal">
A comparison of mammary lesions in MA-treated cats with the incidence of </div>
<div class="MsoNormal">
mammary lesions in untreated cats is given (Table 2). On the basis of this</div>
<div class="MsoNormal">
comparison, only mammary fibroepithelial hyperplasia appears clearly associated</div>
<div class="MsoNormal">
with MA therapy in this study. Fibroepithelial hyperplasia that occurred spontaneously</div>
<div class="MsoNormal">
was seen in young female cats (average age 2.l years), while this condition in</div>
<div class="MsoNormal">
MA-treated cats occurred predominately in older neutered male and female</div>
<div class="MsoNormal">
cats (average age 8.1 years). These observations are entirely consistent with </div>
<div class="MsoNormal">
previous data which link natural and synthetic progestins to the pathogenesis of</div>
<div class="MsoNormal">
feline mammary fibroepithelial hyperplasia.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Two major sub-types of fibroepithelial hyperplasia were identified; an intraductal</div>
<div class="MsoNormal">
form and a solid form. Each sub-type was about equally distributed among</div>
<div class="MsoNormal">
the nine MA-treated cats with this condition. The intraductal form was similar</div>
<div class="MsoNormal">
to a condition previously described as either papillary cystic hypertrophy20 or </div>
<div class="MsoNormal">
intraductal papillary fibroepithelial hyperplasia.8 In this report, </div>
<div class="MsoNormal">
intraductal fibroepithelial hyperplasia was further characterized by papillary </div>
<div class="MsoNormal">
and circumferential growth patterns. The former pattern presented as discrete</div>
<div class="MsoNormal">
growths emanating from segments of duct walls, while the latter pattern was </div>
<div class="MsoNormal">
more compact and annular. We believe the papillary and circumferential growth</div>
<div class="MsoNormal">
patterns represent similar pathologic processes that differ only in the degree of </div>
<div class="MsoNormal">
intraductular proliferation. In one cat (D85-14539), however, atypical epithelium and</div>
<div class="MsoNormal">
focal squamous cell metaplasia were noted in the circumferential growth pattern.</div>
<div class="MsoNormal">
In our experience, squamous metaplasia is an unusual finding in fibroepithelial</div>
<div class="MsoNormal">
hyperplasia, while dysplastic epithelial changes may occasionally be seen. </div>
<div class="MsoNormal">
The solid form of fibroepithelial hyperplasia was similar to that previously described</div>
<div class="MsoNormal">
by us and others.'J5J6 Both intraductal and solid forms of fibroepithelial</div>
<div class="MsoNormal">
hyperplasia evolve around the mammary duct system, but each form interfaces</div>
<div class="MsoNormal">
with the ducts in a different manner; small cysts may be found even in the solid</div>
<div class="MsoNormal">
form of this condition.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Table 2 comparison of the incidence of mammary lesions in </div>
<div class="MsoNormal">
megestrol acetate-treated cats and untreated cats. </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<shape coordsize="21600,21600" id="_x0000_s1028" style="height: 129.75pt; width: 321pt;" type="#_x0000_t75"><imagedata cropbottom="45897f" o:title="4A3CEBF3" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image013.jpg"></imagedata></shape></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
It is noteworthy that M A therapy was associated with intraductal lesions in four of</div>
<div class="MsoNormal">
nine cats with fibroepithelial hyperplasia in the present study as well as in five of six cats </div>
<div class="MsoNormal">
with intraductal lesions in other studies, whereas only one of the 11 untreated cats</div>
<div class="MsoNormal">
with fibroepithelial hyperplasia in the present study had an intraductal lesion. This observation</div>
<div class="MsoNormal">
suggests that therapy with MA, or perhaps other synthetic progestins,</div>
<div class="MsoNormal">
should be considered, especially when intraductal forms of fibroepithelial hyperplasia</div>
<div class="MsoNormal">
are encountered in cats. The role of MA in the genesis of lobular hyperplasia</div>
<div class="MsoNormal">
is unresolved. However, when the time between drug administration and appearance</div>
<div class="MsoNormal">
of lobular hyperplasia was considered, a cause and effect relationship seemed</div>
<div class="MsoNormal">
possible. This notion is further supported by the fact that lobular hyperplasia</div>
<div class="MsoNormal">
occurred in 18% of MA-treated cats versus 3% of untreated cats.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Lobular hyperplasia was characterized by accentuated development of</div>
<div class="MsoNormal">
mammary lobules with some secretory activity. Elongated secretory epithelial cells</div>
<div class="MsoNormal">
with prominent apical blebs were seen in a MA-treated male cat but not</div>
<div class="MsoNormal">
in either MA-treated female cat; nor were these cells found in three untreated cats</div>
<div class="MsoNormal">
with lobular hyperplasia or in prelactational mammary tissue from two normal</div>
<div class="MsoNormal">
pregnant cats evaluated for comparison. Presumably, these elongated epithelial</div>
<div class="MsoNormal">
cells represent a more advanced stage of secretory activity in the MA-treated</div>
<div class="MsoNormal">
male cat since cells with similar morphology are found in fully developed lactating</div>
<div class="MsoNormal">
adenomas in young women. Such lesions in the cat and humans likely represent</div>
<div class="MsoNormal">
a proliferation of normal mammary lobules or ductules, either as a more diffuse</div>
<div class="MsoNormal">
form of hyperplasia or as a neoplastic process. Although progestins (MA and MPA)</div>
<div class="MsoNormal">
have been implicated in mammary cancer in the cat, results of the present</div>
<div class="MsoNormal">
study neither proved nor disproved this association. Prolonged treatment</div>
<div class="MsoNormal">
with progestins in the dog, however, resulted in development of dysplastic</div>
<div class="MsoNormal">
mammary nodules and malignant This underscores the potential risk associated with progestin</div>
<div class="MsoNormal">
therapy, especially when used on a long-term basis. Also, the unusual occurrence</div>
<div class="MsoNormal">
of mammary cancer in an MA-treated, neutered male cat in this study</div>
<div class="MsoNormal">
lends further support for the judicious use of progestins in cats.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Review of the clinicopathologic data (Table 1) revealed</div>
<div class="MsoNormal">
that 13 of the 17 MA-treated cats in this study were neutered males or females.</div>
<div class="MsoNormal">
Presumably, this ratio reflects the large number of neutered animals in the</div>
<div class="MsoNormal">
general cat population. It was not possible from this study to determine</div>
<div class="MsoNormal">
whether neutered cats have more progesterone-responsive clinical problems</div>
<div class="MsoNormal">
than nonneutered cats. Although the daily dose of MA was fairly standard, </div>
<div class="MsoNormal">
the schedule and length of time the drug was given with respect to detection</div>
<div class="MsoNormal">
of lesions was quite variable. Even the type of histologic lesion did not</div>
<div class="MsoNormal">
necessarily correlate well with the dose of MA or duration of therapy.</div>
<div class="MsoNormal">
This indicates that one cannot accurately predict how an individual cat will respond to</div>
<div class="MsoNormal">
MA therapy. However, it should be noted that MA given for as little as</div>
<div class="MsoNormal">
5 weeks was sufficient to induce lobular hyperplasia in one cat (FMT-78).</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Little is known about the specifics of hormonal regulation</div>
<div class="MsoNormal">
of normal mammary growth in the cat. Hormones previously implicated </div>
<div class="MsoNormal">
in mammary growth in general are estrogen, progesterone, growth hormone,</div>
<div class="MsoNormal">
placental lactogen, adrenal corticoids, and possibly thyroid hormone. Synergism</div>
<div class="MsoNormal">
between pituitary hormones and ovarian steroids is essential to achieve maximal</div>
<div class="MsoNormal">
mammary development. Also, hormones may act on mammary growth </div>
<div class="MsoNormal">
indirectly via polypeptide growth factors (e.g., somatomedins). The relative role</div>
<div class="MsoNormal">
that each hormone or hormone combination plays in coordinating mammary growth</div>
<div class="MsoNormal">
varies with the species. For example, estrogen alone has no effect on mammary</div>
<div class="MsoNormal">
tissue in the dog, yet it evokes development of ductal tissue in the cat</div>
<div class="MsoNormal">
and ductular as well as lobulo-alveolar tissue in the goat. There is evidence that</div>
<div class="MsoNormal">
progesterone alone will induce extensive ductal-alveolar proliferation</div>
<div class="MsoNormal">
in neutered dogs. A similar mammogenic response has been demonstrated </div>
<div class="MsoNormal">
in sexually intact beagle dogs given synthetic progestins. How progesterone acts </div>
<div class="MsoNormal">
to effect growth of the mammary gland still is unclear, but recent studies would</div>
<div class="MsoNormal">
indicate several possibilities. Mammary tissue has receptors with high affinity</div>
<div class="MsoNormal">
for progesterone and receptors with low affinity for progesterone which also bind</div>
<div class="MsoNormal">
glucocorticoids. Some investigators believe that progesterone bound to the high</div>
<div class="MsoNormal">
affinity receptor is directly responsible for stimulating mammary gland growth.</div>
<div class="MsoNormal">
Such receptors have been demonstrated in mammary tissue in the cat,</div>
<div class="MsoNormal">
dog, and others. In addition, progesterone may act indirectly by stimulating</div>
<div class="MsoNormal">
release of certain pituitary hormones that effect growth of mammary tissue. </div>
<div class="MsoNormal">
Elevated levels of growth hormone, but not prolactin, have been reported in beagle</div>
<div class="MsoNormal">
dogs with proliferative mammary lesions, established after long-term exposure </div>
<div class="MsoNormal">
to synthetic progestins. The latter mechanism does not appear valid for the</div>
<div class="MsoNormal">
cat since long-term administration of MA to cats failed to induce overproduction</div>
<div class="MsoNormal">
of pituitary growth hormone. Thus we can hypothesize that MA exerts its mammatrophic</div>
<div class="MsoNormal">
effect in the cat by binding directly to progesterone- specific receptors,</div>
<div class="MsoNormal">
by stimulating release of pituitary hormones other than growth hormone (e.g.,</div>
<div class="MsoNormal">
prolactin), or by stimulating synthesis of certain polypeptide growth factors</div>
<div class="MsoNormal">
(e.g., insulin-like growth factor and epidermal growth factor).</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
In conclusion, this retrospective study revealed a spectrum of mammary gland</div>
<div class="MsoNormal">
lesions in MA-treated cats, but only fibroepithelial hyperplasia was clearly</div>
<div class="MsoNormal">
associated with MA therapy. Although several neoplasms were found in this study,</div>
<div class="MsoNormal">
there was no clear cut evidence that MA therapy is causally linked to</div>
<div class="MsoNormal">
mammary neoplasia. Future studies are needed to more fully explore </div>
<div class="MsoNormal">
the pathobiologic relationships between MA and other growth-promoting agents</div>
<div class="MsoNormal">
in progestin associated changes in the mammary gland of cats.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">References</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Allen HL: Feline mammary hypertrophy. Vet Pathol</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Carroll EJ: Lactation. In: Veterinary Endocrinology and</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Reproduction, ed. McDonald LE, 3rd ed., pp. 503-528.</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Lea and Febiger, Philadelphia, 1980</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Chastain CB, Ganjam VK: Clinical Endocrinology of</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Companion Animals, pp. 543-544. Lea and Febiger,</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Philadelphia, 1986</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Chastain CB, Graham CL, Nichols CE: Adrenocortical</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">suppression in cats given megestrol acetate. Am J Vet</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Res 42:2029-2035, 1981</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Chatterton RT: Mammary gland: development and secretion.</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Obstet Gynecol Annu 7:303-324, 1978</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">10:501-508, 1973</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">6 Concannon PW, Spraker TR, Casey HW, Hansel W:</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Gross and histopathologic effects of medroxyprogesterone</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">acetate and progesterone on the mammary glands of</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">adult beagle bitches. Fertil Steril 36373-387, 198 1</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">7 David A, Edwards K, Fellowes KP, Plummer JM: Antiovulatory</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">and other biological properties of megestrol</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">acetate, 17a-acetoxy-6 methyl pregna 4 : 6-diene-3 : 20-</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">dione (BDH 1298). J Reprod Fertil5331-346, 1963</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">8 Dorn AS, Legendre AM, McGavin MD: Mammary</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">hyperplasia in a male cat receiving progesterone. J Am</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Vet Med Assoc 182:621-622, 1983</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">9 Forsyth IA: The endocrinology of lactation. In: Biochemistry</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">of Lactation, ed. Mepham TB, pp. 309-349.</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Elsevier, Amsterdam, 1983</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">10 Frank DW, Kirton KT, Murchison TE, Quinlan WJ,</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Coleman ME, Gilbertson TJ, Feenstra ES, Kimball F A</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Mammary tumors and serum hormones in the bitch</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">treated with medroxyprogesterone acetate or progesterone</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">for four years. Fertil Steril31:340-346, 1979</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">1 1 Fulkerson W J: Hormonal Control of Lactation, Annual</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Research Reviews, ed. Horrobin DF, vol. 1, pp. 4-2 1.</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Eden Press, Montreal, Canada, 1979</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">12 Giles RC, Kwapien RP, Geil RG, Casey HW: Mammary</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">nodules in beagle dogs administered investigational</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">oral contraceptive steroids. J Natl Cancer Inst 60: 135 1-</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">1364, 1978</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">13 Graf KJ, Etreby M F The role of the anterior pituitary</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">from progestogen induced proliferative mammary gland</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">changes in the beagle. Acta Endocrinol 85(Suppl 2 12):</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">49, 1977</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">14 Hampe JF, Misdorp W: IX. Tumors and dysplasias of</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">the mammary gland. In: International Histological Classification</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">of Tumors of Domestic Animals, ed. Beveridge</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">WIB and Sobin LH. Bull WHO 5O:lll-133, 1974</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">15 Hayden D W, Johnson KH: Feline mammary hypertrophy-</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">fibroadenoma complex. In: Current Veterinary</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Therapy IX, ed. Kirk RW, pp. 477480. WB Saunders,</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Philadelphia, 1986</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">16 Hayden DW, Johnston SD, Gang DT, Johnson KH,</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Barnes DM: Feline mammary hypertrophy/fibroadenoma</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">complex: clinical and hormonal aspects. Am J Vet</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Res 421699-1703, 1981</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">17 Henik RA, Olson PN, Rosychuk RAW: Progestogen</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">therapy in cats. Compend Cont Ed Pract Vet 7: 132-14 1,</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">1985</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">18 Hernandez FJ, Fernandez BB, Chertack M, Gage PA:</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Feline mammary carcinoma and progestogens. Feline</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Pract 5(5):4548, 1975</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">19 Hertel BF, Zaloudek C, Kempson RL: Breast adenomas.</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Cancer 312891-2905, 1976</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">20 Hinton M, Gaskell C J: Non-neoplastic mammary hypertrophy</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">in the cat associated either with pregnancy or</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">with oral progestagen therapy. Vet Rec 100:277-280,</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">1977</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">21 Janne 0, Kontula K, Vihko R, Feil PD, Bardin CW:</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Progesterone receptor and regulation of progestin action</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">in mammalian tissues. Med Biol 56:225-248, 1978</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">22 Johnston SD, Hayden DW, Gang DT, Handschin B,</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Johnson KH: Progesterone receptors in feline mammary</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">adenocarcinomas. Am J Vet Res 45379-382, 1984</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Downloaded from vet.sagepub.com by guest on March 8, 2012</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Megestrol Acetate and Mammary Morphology in Cats 113</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">23 Kunkle GA: Progestagens in dermatology. In: Current</span></div>
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<span style="font-size: 8pt;">Veterinary Therapy IX, ed. Kirk RW, pp. 601-605. WB</span></div>
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<span style="font-size: 8pt;">Saunders, Philadelphia, 1986</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">24 Kwapien RP, Giles RC, Geil RG, Casey HW: Basaloid</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">adenomas of the mammary gland in beagle dogs administered</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">investigational contraceptive steroids. J Natl Cancer</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Inst 59:933-939, 1977</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">25 Kwapien RP, Giles RC, Geil RG, Casey HW: Malignant</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">mammary tumors in beagle dogs dosed with investigational</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">oral contraceptive steroids. J Natl Cancer</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Inst 65:137-144, 1980</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">26 Nimmo-Wilke JS: Progesterone therapy for cats. Can</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Vet J 20:164, 1979</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">27 Oen EO: The oral administration of megestrol acetate</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">to postpone oestrus in cats. Nord Vet Med 29:287-29 1,</span></div>
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<span style="font-size: 8pt;">1977</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">28 Peterson ME: Effects of megestrol acetate on glucose</span></div>
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<span style="font-size: 8pt;">tolerance and growth hormone secretion in the cat. Res</span></div>
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<span style="font-size: 8pt;">Vet Sci 42:354-357, 1987</span></div>
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<span style="font-size: 8pt;">29 Pierrepoint CG, Thomas SE, Eaton C L Studies with</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">mammary tumors of the bitch. In: Progress in Cancer</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Research and Therapy, ed. Bresciani F, King RJB, Lippman</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">ME, Namer M, and Raynaud JP, vol. 3 1, pp. 349-</span></div>
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<span style="font-size: 8pt;">355. Raven Press, New York, 1984</span></div>
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<span style="font-size: 8pt;">30 Pukay BP: A hyperglycemia-glucosuna syndrome in cats</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">following megestrol acetate therapy. Can Vet J 20: 1 17,</span></div>
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<span style="font-size: 8pt;">1979</span></div>
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<span style="font-size: 8pt;">3 1 Raynaud JP, Cotard M, Andre F, Mialot JP, Rolland</span></div>
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<span style="font-size: 8pt;">PH, Martin PM: Spontaneous canine mammary tumors:</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">a model for human endocrine therapy? J Steroid</span></div>
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<span style="font-size: 8pt;">Biochem 1520 1-207, 198 1</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">32 Seiler RJ, Kelly WR, Menrath VH, Barber0 RD: Total</span></div>
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<span style="font-size: 8pt;">fibroadenomatous change of the mammary glands of two</span></div>
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<span style="font-size: 8pt;">spayed cats. Feline Pract 9(2):25-29, 1979</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">33 Tomlinson MJ, Barteaux L, Ferns LE, Angelopoulos E:</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Feline mammary carcinoma: a retrospective evaluation</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">of 17 cases. Can Vet J 25435439, 1984</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">34 Trentin JJ, DeVita J, Gardner WU: Effects of moderate</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">doses of estrogen and progesterone on mammary growth</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">and hair growth in dogs. Anat Rec 113:163-177, 1952</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">35 Tucker HA: Endocrine and neural control of the mammary</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">gland. In: Lactation, ed. Larson BL, pp. 39-79.</span></div>
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<span style="font-size: 8pt;">Iowa State University Press, Ames, IA, 1985</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">Request reprints from Dr. D. W. Hayden, Department of Veterinary Pathobiology, College of Veterinary Medicine, University</span></div>
<div class="MsoNormal">
<span style="font-size: 8pt;">of Minnesota, St. Paul, MN 55108 (USA).</span></div>
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<span style="color: black; font-size: 8pt;">Downloaded from </span><span style="color: blue; font-size: 8pt;">vet.sagepub.com </span><span style="color: black; font-size: 8pt;">by guest on March 8, 2012</span></div>
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<br /></div>
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<b><span style="font-size: 16pt;">15)<a href="http://www.ncbi.nlm.nih.gov/pubmed/2647696" style="color: blue; text-decoration: underline; text-underline: single;">Use of megestrol acetate in cats.</a></span></b></div>
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Romatowski J.</div>
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J Am Vet Med Assoc. 1989 Mar 1;194(5):700-2. Review.. </div>
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PMID:</div>
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2647696</div>
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[PubMed - indexed for MEDLINE] </div>
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<br /></div>
<div class="MsoNormal">
No abstract available</div>
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<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">16)<a href="http://www.ncbi.nlm.nih.gov/pubmed/3399866" style="color: blue; text-decoration: underline; text-underline: single;">[What is your diagnosis? Which treatment do you suggest? An unusual case of an aggravated secondary reaction of megestrol acetate therapy].</a></span></b></div>
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Kubinetz M.</div>
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Schweiz Arch Tierheilkd. 1988 May;130(5):275-6. German</div>
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<br /></div>
<div class="MsoNormal">
. No abstract available. </div>
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<br /></div>
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<b><span style="font-size: 16pt;">17)<a href="http://www.ncbi.nlm.nih.gov/pubmed/3039622" style="color: blue; text-decoration: underline; text-underline: single;"><span style="text-decoration: none;">Effects of megestrol acetate on glucose tolerance and growth hormone secretion in the cat.</span></a></span></b></div>
<div class="MsoNormal">
Peterson ME.</div>
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Res Vet Sci. 1987 May;42(3):354-7.</div>
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PMID:</div>
<div class="MsoNormal">
3039622</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Abstract</div>
<div class="MsoNormal">
Long-term administration of relatively high therapeutic dosages of megestrol acetate to cats produced a progressive deterioration in glucose tolerance, with a significant (P less than 0.05) increase in mean fasting plasma glucose concentrations and decrease in mean plasma glucose clearance rates after six and 12 months of treatment. There appeared to be no relationship, however, between the development of glucose intolerance and circulating growth hormone (GH) concentrations in the cats of this study, since no significant rise in plasma GH concentrations was detected during the 12 month period of megestrol acetate treatment. Administration of megestrol acetate also produced a progressive decrease in both resting plasma cortisol concentrations and cortisol concentrations after ACTH stimulation. Three months after discontinuation of megestrol acetate, the elevated fasting plasma glucose concentrations, decreased glucose clearance rates and subnormal plasma cortisol concentrations all returned to normal pretreatment values, indicating resolution of glucose intolerance and hypoadrenocorticism. The results of this study demonstrate that administration of megestrol acetate to cats can produce a state of moderate to severe glucose intolerance, which is usually reversible after cessation of treatment. Although the exact mechanism of the glucose intolerance and overt diabetes mellitus induced by progestagen treatment of cats remains unclear, it is likely that these alterations in glucose metabolism result primarily from the glucocorticoid activity intrinsic to megestrol acetate.</div>
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PMID:</div>
<div class="MsoNormal">
3039622</div>
<div class="MsoNormal">
[PubMed - indexed for MEDLINE] </div>
<div class="MsoNormal">
<br /></div>
<div class="title">
<br /></div>
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<b><span style="color: blue; font-size: 16pt;">18)Suppression of cortisol responses to exogenous adrenocorticotrophic </span></b></div>
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<b><span style="color: blue; font-size: 16pt;">hormone, and the occurrence of side effects attributable to glucocorticoid excess, in cats during therapy with megestrol acetate and prednisolone</span><span style="font-size: 16pt;">.</span></b></div>
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Middleton DJ, Watson AD, Howe CJ, Caterson ID.</div>
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Can J Vet Res. 1987 Jan;51(1):60-5.</div>
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<br /></div>
<form>
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<span style="color: #212121; display: none; font-size: 11.5pt;"><input name="p$a" type="hidden" /> <input name="p$l" type="hidden" value="PPMCLayout" /> <input name="p$st" type="hidden" value="pmc" /> <input name="SessionId" type="hidden" value="396B5177F58CCDC1_0087SID" /> <input name="Snapshot" type="hidden" value="/projects/PMC/PPMC@1.130" /> </span></div>
<br />
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</div>
<div class="MsoNormal">
Suppression of Cortisol Responses to Exogenous Adrenocorticotrophic Hormone, and the Occurrence of</div>
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Side Effects Attributable to Glucorticoid Excess, in Cats during Therapy with Megestrol Acetate and Prednisolone</div>
<div class="MsoNormal">
Deborah J. Middleton, A. David J. Watson, Christopher J. Howe and Ian D. Caterson*</div>
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ABSTRACT</div>
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The major purpose of this investigation was to determine the effect of prednisolone and megestrol acetate in</div>
<div class="MsoNormal">
cats on the adrenal cortisol response to exogenous adrenocorticotrophic hormone during drug administration</div>
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at dose rates employed for management of some inflammatory feline dermatoses. Prednisolone (at least</div>
<div class="MsoNormal">
2 mg/kg/day) and megestrol acetate (5 mg/cat/day) were each administered orally to seven cats from days 1</div>
<div class="MsoNormal">
to 16. Three additional cats received no therapy. Basal and stimulated cortisol concentrations, food and water</div>
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intake, hematology, blood biochemistry, urinalyses, and hepatic and cutaneous histology were studied in all</div>
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cats before, during, and two weeks following the end of treatment. Cats given prednisolone or megestrol acetate</div>
<div class="MsoNormal">
had significant suppression of stimulated cortisol levels on day 8. This change was more marked on day</div>
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15, when the suppression in cats given megestrol acetate was also significantly more severe than in those receiving</div>
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prednisolone. Recovery of adrenal reserve was considered present on day 30 in six of seven cats given prednisolone,</div>
<div class="MsoNormal">
but in only three of seven receiving megestrol acetate. Eosinopenia, glycosuria and hepatocyte swelling</div>
<div class="MsoNormal">
from glycogen deposition were occasionally recorded in treated cats of both groups, providing additional</div>
<div class="MsoNormal">
circumstantial evidence for glucocorticoid activity of megestrol acetate in cats. It is advised that abrupt withdrawal</div>
<div class="MsoNormal">
of prednisolone or megestrol acetate therapy be avoided in this species to reduce the chance of precipitating</div>
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clinical signs of hypoadrenocorticism, even after treatment for as little as one week.</div>
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Key words: Cat diseases, progestational hormones, synthetic, glucocorticoids, megestrol acetate, prednisolone.</div>
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<br /></div>
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<br /></div>
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*Department of Veterinary Pathology (Middleton) and Department of Veterinary Clinical Studies (Watson), The University of Sydney, 2006, Australia and Department of Endocrinology, Royal Prince Alfred Hospital, Camperdown, 2050, Australia (Howe, Caterson). Present address of Dr. Middleton:</div>
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Department of Pathology, Royal Veterinary College, Royal College Street, London NW1 OTU, England.</div>
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Reprints are not available.</div>
<div class="MsoNormal">
This work was supported by the Hugh Hughes Bequest, the Departments of Veterinary Pathology and Veterinary Clinical Studies, The University of Sydney and the Department of Endocrinology, Royal Prince Alfred Hospital.</div>
<div class="MsoNormal">
Submitted January 29, 1986.</div>
<div class="MsoNormal">
60 Can J Vet Res 1987; 51: 60-65</div>
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<br /></div>
<div class="MsoNormal">
INTRODUCTION</div>
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<br /></div>
<div class="MsoNormal">
The potency of glucocorticoids, as measured by their ability to deposit hepatic glycogen, and their other</div>
<div class="MsoNormal">
properties, including anti-inflammatory activity and suppression of synthesis and secretion of adrenocorticotrophic</div>
<div class="MsoNormal">
hormone (ACTH), tend to parallel one another (1,2). However, cortisol responses to ACTH remained</div>
<div class="MsoNormal">
normal in six cats receiving various oral prednisolone regimes for four weeks (3), including two animals given</div>
<div class="MsoNormal">
doses approximating that recommended for anti-inflammatory activity in cats 4). Veterinary clinicians generally suspect</div>
<div class="MsoNormal">
that the progestin, megestrol acetate, also exhibits glucocorticoid activity in cats, although its mode of</div>
<div class="MsoNormal">
therapeutic action in dermatological conditions such as miliary dermatitis and the eosinophilic granuloma complex</div>
<div class="MsoNormal">
is not precisely known (5,6). Previous work (7) has documented low basal cortisol levels and hypo-responsiveness</div>
<div class="MsoNormal">
to ACTH in three chemically restrained cats one week following completion of two weeks therapy with</div>
<div class="MsoNormal">
megestrol acetate. However, basal and stimulated cortisol concentrations before and during the treatment period,</div>
<div class="MsoNormal">
in both untreated and treated cats, were sufficiently high to suggest interference by chemically induced or</div>
<div class="MsoNormal">
environmental stress. It is therefore possible that these data do not precisely reflect the influence of megestrol acetate on feline cortisol concentrations during therapy. Prednisolone (or prednisone) treatment in dogs, in addition to reducing</div>
<div class="MsoNormal">
the adrenal reserve (8,9), is regularly associated with other changes attributable to glucocorticoid excess, such</div>
<div class="MsoNormal">
as eosinopenia and lymphocytopenia, abnormal hepatic morphology, and increased serum alkaline phosphatase</div>
<div class="MsoNormal">
(ALP), alanine aminotransferase (ALT), and -y-glutamyltranspeptidase (-y-GPT) concentrations (8,10-12).</div>
<div class="MsoNormal">
Development of similar abnormalities has not been studied in cats given prednisolone or megestrol acetate.</div>
<div class="MsoNormal">
The purpose of this study was to reassess effects of prednisolone and megestrol acetate, administered at</div>
<div class="MsoNormal">
dose rates employed clinically for control of inflammatory skin diseases, on basal and ACTH stimulated cortisol</div>
<div class="MsoNormal">
concentrations in cats, and to document the occurrence or otherwise of more overt signs of glucocorticoid</div>
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excess. </div>
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<br /></div>
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MATERIALS AND METHODS</div>
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<br /></div>
<div class="MsoNormal">
Seventeen adult domestic cats (males and females) weighing between 2.6 and 4.6 kg were obtained from The</div>
<div class="MsoNormal">
University of Sydney Animal House. Each cat was clinically normal, immunized against feline panleukopenia</div>
<div class="MsoNormal">
virus infection, treated for nematode and cestode endoparasites, and was well socialized towards people. Cats</div>
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were housed individually in cages measuring 1 m x I m x 2 m and containing exercise platforms. They were</div>
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given water and a nutritionally complete dry cat food (Go-Cat, Carnation Co, Blacktown, N.S.W., Australia) ad</div>
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lib, and acclimatized for at least one month before use. The experiment was conducted in late spring to early summer</div>
<div class="MsoNormal">
with augmentation of natural illumination by fluorescent light during daylight hours. Food (g/ kg of bodyweight) and water (mL/ kg of bodyweight) intake of each cat were measured daily for eight days before treatment commenced, and for the</div>
<div class="MsoNormal">
subsequent month. Bodyweight was recorded weekly. At 6:00 p.m. on days I to 16, seven cats (including two entire males and one desexed male) were given 5 mg megestrol acetate orally (Ovarid, Glaxo, North Ryde, N.S.W., Australia).</div>
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Similarly, seven cats (including two entire males and one desexed male) received prednisolone (Deltacortef,</div>
<div class="MsoNormal">
Upjohn, Rydalmere, N.S.W., Australia; Panafcortelone " ", Protea, Glebe, N.S.W., Australia) at a dose of</div>
<div class="MsoNormal">
2 mg/ kg. The dose of prednisolone was raised to 4 mg/ kg in two cats for the second week. Three animals (including</div>
<div class="MsoNormal">
one entire and one desexed male) were not given megestrol acetate or prednisolone in order to monitor</div>
<div class="MsoNormal">
the effects of sampling procedures on the variables under assessment. Blood samples were collected from</div>
<div class="MsoNormal">
the jugular vein of each cat for hematological and biochemical analyses two days before the start of treatment</div>
<div class="MsoNormal">
(day 1) and on days 4, 7, 14 and 29. Anti-coagulated (EDTA) blood was used for determination of packed cell</div>
<div class="MsoNormal">
volume (PCV), total plasma protein concentration (TPP), and leukocyte count and differentiation by routine</div>
<div class="MsoNormal">
methods. Heparinized plasma was assayed for ALT, ALP and aspartate aminotransferase (AST) activities, and</div>
<div class="MsoNormal">
serum for -y-GTP activity using commercially available reagents (Calbiochem- Behring, La Jolla, California;</div>
<div class="MsoNormal">
Smith Kline Instruments, Sunnyvale, California). Serum protein electrophoresis was also done and plasma</div>
<div class="MsoNormal">
Icteric Index determined (13). Adrenocorticotrophic hormone response tests were performed after a 14</div>
<div class="MsoNormal">
to 16 hour fast and completed between 8:00 a.m. and 10:30 a.m. on days 0, 8, 15 and 30. Venous blood samples were</div>
<div class="MsoNormal">
collected for cortisol estimations immediately before, and one hour after, intramuscular injection of 2.2 units/</div>
<div class="MsoNormal">
kg corticotropin gelatin injection (ACTHAR gel, Armour Pharmaceuticals, Eastbourne, England). Plasma</div>
<div class="MsoNormal">
was stored at -20°C and cortisol assays were performed within one week. Cortisol was estimated by a solid-phase</div>
<div class="MsoNormal">
radioimmunoassay kit marketed for clinical use in humans (Gammacoat Cortisol, Clinical Assays, Cambridge,</div>
<div class="MsoNormal">
Massachusetts). Validation of the cortisol radioimmunoassay for use in cats was done using methods similar to</div>
<div class="MsoNormal">
those previously described (14). Major cross-reacting steroids with this assay included prednisolone (87.5%), 11-</div>
<div class="MsoNormal">
deoxycortisol (6.3%) cortisone (4.5%), prednisone (3.9%), corticosterone (2.5%), and deoxycorticosterone</div>
<div class="MsoNormal">
(2.1 %). Cross-reaction of megestrol acetate was less than 0.01%. Sensitivity was calculated as 15.5 nmol/ L on 40</div>
<div class="MsoNormal">
cortisol assays; for statistical analysis undetectable levels were assigned the value of 16 nmol/ L. Intra-assay variation</div>
<div class="MsoNormal">
was 8.3% for the low, and 3.1% for the high, control; while the inter-assay variation was 8.6% for both controls.</div>
<div class="MsoNormal">
Standards employed contained cortisol in the following concentrations; 0, 55, 138, 276, 690, and 1655 nmol/L.</div>
<div class="MsoNormal">
After each ACTH response test, general anesthesia was induced with thiopentone and maintained with halothane, nitrous oxide and oxygen. The urinary bladder was catheterized and urine collected for routine urinalysis.</div>
<div class="MsoNormal">
Using aseptic technique a liver biopsy was collected via a small laparotomy and a skin biopsy was taken</div>
<div class="MsoNormal">
from the lumbar area using a 6 mm punch; wound closures were routine. The skin biopsy and a portion of the</div>
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61 liver tissues were placed in 10% neutral buffered formalin. Six-micron sections from formalin-fixed paraffin embedded</div>
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biopsy tissues were stained with hematoxylin and eosin for light microscopic examination. The remainder</div>
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of the liver tissue was cut into 1 mm cubes, fixed in 2.5% glutaraldehyde in sodium cacodylate buffer and</div>
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processed for electron microscopy. Statistical methods were employed in evaluation of the following: food</div>
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and water intake, lymphocyte and eosinophil counts, and cortisol concentrations. These methods comprised</div>
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analyses of variance and, when indicated, unpaired t-tests. Statistical significance was taken at the 5% level.</div>
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<br /></div>
<div class="MsoNormal">
RESULTS</div>
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<br /></div>
<div class="MsoNormal">
GENERAL COMMENTS</div>
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<br /></div>
<div class="MsoNormal">
All cats remained clinically well during the experiment. Results from the two cats whose prednisolone dose</div>
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was increased in the second week did not exhibit differences from other cats in the group so the data were</div>
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combined.</div>
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<br /></div>
<div class="MsoNormal">
PLASMA CORTISOL LEVELS</div>
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Basal and ACTH-stimulated plasma cortisol concentrations before, during, and after treatment are presented</div>
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in Fig. 1.</div>
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For statistical analysis resting cortisol levels were studied unchanged while ACTH-stimulated cortisol data</div>
<div class="MsoNormal">
were log-transformed to achieve homogeneity of variance. There were no significant differences between the</div>
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three groups of cats for pretreatment resting or stimulated cortisol levels. With regard to resting levels throughout</div>
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the experiment, a significant difference between cats was noted and was statistically attributable to the</div>
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treatment group, with animals given megestrol acetate having, overall, significantly lower basal cortisol levels</div>
<div class="MsoNormal">
than untreated cats. Within individual cats, there was a significant difference in resting cortisol concentration related</div>
<div class="MsoNormal">
to the stage of the experiment as there was a decrease overall in basal levels as the experiment progressed.</div>
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For ACTH-stimulated cortisol concentrations, a significant difference between cats was detected in relation</div>
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to treatment group, and within cats in relation to the stage of the experiment, reflecting suppression of the cortisol</div>
<div class="MsoNormal">
response to ACTH after both one and two weeks of prednisolone and megestrol acetate therapy. The degree of</div>
<div class="MsoNormal">
adrenal suppression induced by prednisolone and megestrol acetate after one week of dosage was similar for</div>
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the two drugs, but after two weeks the abnormality in megestrol acetate treated animals was significantly more</div>
<div class="MsoNormal">
severe. Individual animal data suggested return of adrenal reserve was present two weeks after drug administration</div>
<div class="MsoNormal">
ceased in six of seven cats given prednisolone, but in only three of seven given megestrol acetate. Additional</div>
<div class="MsoNormal">
ACTH stimulation tests were performed in cats in which recovery was considered incomplete, and normal</div>
<div class="MsoNormal">
responses were documented after a further one or two weeks.</div>
<div class="MsoNormal">
250</div>
<div class="MsoNormal">
200 -</div>
<div class="MsoNormal">
E 150</div>
<div class="MsoNormal">
c</div>
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0L-,- 100</div>
<div class="MsoNormal">
o</div>
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50</div>
<div class="MsoNormal">
50-</div>
<div class="MsoNormal">
T</div>
<div class="MsoNormal">
T</div>
<div class="MsoNormal">
II</div>
<div class="MsoNormal">
T</div>
<div class="MsoNormal">
II</div>
<div class="MsoNormal">
p</div>
<div class="MsoNormal">
II.</div>
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0123</div>
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O 1 2 3 4</div>
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Weeks</div>
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U n=3</div>
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It was determined statistically that drug treatments had been randomized between the three groups of cats with</div>
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regard to food and water consumption. There were no significant differences for food intake between groups</div>
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during or after treatment. However, cats given megestrol acetate drank slightly, but significantly, more than</div>
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the other two groups during treatment. Cats given prednisolone drank slightly, but significantly, less than the</div>
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untreated and megestrol acetate-treated cats in the post treatment period.</div>
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<br /></div>
<div class="MsoNormal">
HEMATOLOGY</div>
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<br /></div>
<div class="MsoNormal">
Packed cell volume and TPP measurements remained within laboratory normal ranges. No significant differences</div>
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were detected in lymphocyte numbers for untreated cats over time, or between untreated and treated cats</div>
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at any stage of the experiment. One cat given prednisolone was lymphocytopenic (<0.600 x 109 cells/ L) on day 14.</div>
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Untreated cats had significantly different eosinophil counts from each other, but within this group eosinophil</div>
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numbers did not change significantly T</div>
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-I</div>
<div class="MsoNormal">
I</div>
<div class="MsoNormal">
T</div>
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-II</div>
<div class="MsoNormal">
0</div>
<div class="MsoNormal">
T</div>
<div class="MsoNormal">
l 0 -r I~~~~~~~~~</div>
<div class="MsoNormal">
O 1 2 3 4v</div>
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Weeks</div>
<div class="MsoNormal">
MA n=7</div>
<div class="MsoNormal">
j Pre-ACTH</div>
<div class="MsoNormal">
T Post- ACTH</div>
<div class="MsoNormal">
T</div>
<div class="MsoNormal">
II</div>
<div class="MsoNormal">
T I o</div>
<div class="MsoNormal">
I</div>
<div class="MsoNormal">
I</div>
<div class="MsoNormal">
T II</div>
<div class="MsoNormal">
11 I</div>
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I</div>
<div class="MsoNormal">
0134</div>
<div class="MsoNormal">
O 1 2 3 4v</div>
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Weeks</div>
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P n=7</div>
<div class="MsoNormal">
T</div>
<div class="MsoNormal">
II</div>
<div class="MsoNormal">
during the experiment. There was no significant difference in pretreatment eosinophil counts between the three</div>
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groups of cats. Treated cats had significantly lower eosinophil counts than the untreated group on day 4 and also</div>
<div class="MsoNormal">
day 29, although the latter difference was less marked. There was no significant difference in the degree of</div>
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62</div>
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Fig. 1. Median basal and ACTH-stimulated plasma cortisol concentrations (range indicated by</div>
<div class="MsoNormal">
vertical bars) before (O weeks), during (1 and 2 weeks), and after (4 week’s) treatment with megestrol</div>
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acetate (MA), prednisolone (P), or no drug (U).</div>
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FOOD AND WATER INTAKE</div>
<div class="MsoNormal">
response for the two drugs. In addition, four cats given prednisolone were eosinopenic on day 14 (<0.040 x</div>
<div class="MsoNormal">
109 cells/L), and on days 7 and 14 single cats in the megestrol acetate group had eosinopenia (Table I).</div>
<div class="MsoNormal">
BLOOD CHEMISTRY </div>
<div class="MsoNormal">
Occasional (five of 340 estimations),u p to threefold, elevations were recorded in enzyme concentrations.</div>
<div class="MsoNormal">
These occurred irrespective of the treatment group or stage of the experiment. No abnormalities developed</div>
<div class="MsoNormal">
in serum protein electrophoresis or Icteric Index.</div>
<div class="MsoNormal">
URINALYSES</div>
<div class="MsoNormal">
Results of analysis were normal in all cats before treatment and remained so in untreated animals. Of cats given</div>
<div class="MsoNormal">
prednisolone, one desexed female had pyuria, bacteriuria and glycosuria (2%) on day 15, and a desexed male</div>
<div class="MsoNormal">
had glycosuria (trace) on day 8 and day 15 (I%). Glycosuria (0.25% and 0.5%) was present on day 8 in two entire</div>
<div class="MsoNormal">
males given megestrol acetate.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
HEPATIC AND CUTANEOUS HISTOLOGY</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Tissue from all liver biopsies appeared normal before therapy; and remained so in the untreated group.</div>
<div class="MsoNormal">
Diffuse hepatocyte swelling, as judged by sinusoidal compression, and pallor were present on day 8 in two cats given</div>
<div class="MsoNormal">
megestrol acetate (Fig. 2) and in one cat given prednisolone. The distended hepatocyte cytoplasm appeared to</div>
<div class="MsoNormal">
contain a fine reticulum enclosing multiple vacuole-like areas. Two of the three cats with histological liver</div>
<div class="MsoNormal">
lesions were among those developing glycosuria All skin biopsies were histologically normal. In particular, hyperkeratosis,</div>
<div class="MsoNormal">
epidermal and pilosebaceous atrophy, and calcinosis cutis were not detected. Due to an error in processing, resinembedded liver specimens were not suitable for electron microscopic demonstration of glycogen within</div>
<div class="MsoNormal">
hepatocytes. However, hepatocytes appearing abnormal on light microscopy were shown, ultrastructurally,</div>
<div class="MsoNormal">
to have an expanded cytoplasm with reorientation of intracytoplasmic organelles, notably mitochondria, to the</div>
<div class="MsoNormal">
periphery of the cell.</div>
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<br /></div>
<div class="MsoNormal">
<shape coordsize="21600,21600" id="_x0000_s1027" style="height: 259.5pt; width: 175.5pt;" type="#_x0000_t75"><imagedata cropbottom="4351f" cropleft="22711f" cropright="23938f" croptop="21755f" o:title="" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image015.png"></imagedata></shape></div>
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<br /></div>
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<br /></div>
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<br /></div>
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<br /></div>
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<shape coordsize="21600,21600" id="_x0000_s1026" style="height: 323.25pt; width: 164.25pt;" type="#_x0000_t75"><imagedata cropleft="23324f" cropright="24552f" croptop="16534f" o:title="" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image017.png"></imagedata></shape></div>
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<br /></div>
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<br /></div>
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<br /></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
DISCUSSION</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
Basal cortisol concentrations recorded in all cats before treatment, and in untreated cats throughout the experimental</div>
<div class="MsoNormal">
period, were towards the lower end of baseline values reported for cats by other workers (3,15-17), and, even allowing for different assay methods, were consistent with the blood specimens having been obtained from unstressed cats. Suppression of cortisol responses to ACTH after one and two weeks of megestrol acetate therapy is probably thus an accurate reflection of the influence of this drug on the feline adrenal cortex, and is in contrast to a previous report (7). The</div>
<div class="MsoNormal">
comparative severity of megestrol acetate-induced adrenal suppression relative to that found after prednisolone</div>
<div class="MsoNormal">
in the present study may be due to prednisolone having a shorter half-life, rather than being a reflection of relative</div>
<div class="MsoNormal">
potency. Considering the degree of cross-reaction of prednisolone in the cortisol assay, the low basal levels of</div>
<div class="MsoNormal">
measured cortisol suggested circulating levels of prednisolone in the cats were negligible about 12 hours after</div>
<div class="MsoNormal">
dosage, whereas it is well recognized that megestrol acetate administration may be adequate just once or twice</div>
<div class="MsoNormal">
weekly for remission of medical conditions in cats. This implies a longer biological half-life for megestrol acetate</div>
<div class="MsoNormal">
in cats. Similarly, the more rapid recovery of adrenal responsiveness to ACTH in cats given prednisolone</div>
<div class="MsoNormal">
compared with those given megestrol acetate is consistent with pharmacological concentrations remaining in</div>
<div class="MsoNormal">
the circulation for different times. We have no explanation for the failure of others (3) to document adrenal insufficiency</div>
<div class="MsoNormal">
in cats given prednisolone, except that the higher of their dose rates (5 mg per cat) was slightly lower than 2 mg/ kg. It has also been shown that a normal cortisol response to exogenous ACTH does not exclude the possibility of secondary adrenal insufficiency (18). It may be assumed that prednisolone-induced adrenal cortical suppression in cats is mediated by feedback inhibition of ACTH storage and secretion, but this explanation may not be complete for megestrol</div>
<div class="MsoNormal">
acetate as it has been suggested that medroxyprogesterone acetate in rats 63 exerts a direct toxic effect on the</div>
<div class="MsoNormal">
adrenal cortex as well (19). Measurement of plasma ACTH levels in cats given megestrol acetate would define</div>
<div class="MsoNormal">
the site of drug activity more precisely. Light microscopic changes in the livers of a few cats receiving prednisolone</div>
<div class="MsoNormal">
or megestrol acetate were generally similar to those occurring in glucocorticoid treated dogs (8,11,12,24,25),</div>
<div class="MsoNormal">
and unlike lesions sometimes associated with general anesthesia (26). The appearance of distended hepatocytes</div>
<div class="MsoNormal">
with cytoplasm containing a fine reticulum enclosing large vacuoles is said to be typical of glycogen overload</div>
<div class="MsoNormal">
(24), and redistribution of mitochondria to the cellular periphery has also been observed in cortisone treated rats</div>
<div class="MsoNormal">
(27). It is likely that the duration of treatment, with prednisolone at least, in the present study was too short to</div>
<div class="MsoNormal">
elicit cutaneous atrophy as skin changes consistent with glucocorticoid excess, such as hyperkeratosis, epidermal</div>
<div class="MsoNormal">
atrophy, and alopecia, are recognized in cats with naturally-occurring hyperadrenocorticism (15,28,29), and</div>
<div class="MsoNormal">
prolonged therapy with methylprednisolone (3). Prolonged treatment with methylprednisolone acetate produced a twofold</div>
<div class="MsoNormal">
increase in food intake in two cats (3), and megestrol acetate is frequently employed as an appetite stimulant for</div>
<div class="MsoNormal">
feline patients. However, short term dosage with either prednisolone or megestrol acetate here did not significantly</div>
<div class="MsoNormal">
increase the food intake of normal cats. While it is possible that a modification of ingestive behaviour was reflected by megestrol acetate treated cats drinking more than those given prednisolone, we are not convinced the difference was clinically important. Prednisolone and megestrol acetate appear to reduce circulating numbers of eosinophils in the cat. However, as eosinopenia did not always occur, isolated eosinophil counts may not be useful to assess the presence of pharmacological levels of glucocorticoids in clinical cases. No evidence was found for an influence of either drug on lymphocyte numbers, but it is recognized that the lympholytic action in particular of glucocorticoids varies between species (20). As the number of untreated cats was smaller than either treatment group, interpretation of the findings of glycosuria and changes in hepatic morphology, which were not subjected to analysis, must be cautious. However, glycosuria identified in four treated cats is unlikely to be attributable to an influence of exogenous ACTH on gluconeogenesis, as mediated by stimulated blood cortisol levels, because glycosuria was not found in any pretreatment,</div>
<div class="MsoNormal">
post-ACTH urine specimens, or in any urine specimens from untreated cats. In addition, on the occasions when lycosuria was observed, the post-ACTH cortisol concentrations were abnormally low. Short term therapies with megestrol acetate and prednisolone have been shown to induce impaired elimination of an intravenous glucose load in cats, and fasting hyperglycemia as well in some cats (21). Although urine glucose determinations are not a precise measure of glucose intolerance, glycosuria is not a normal finding in unfed cats. It is probable that glycosuria recorded in a few cats of this study reflected hyperglycemia, and similar effects of glucocorticoids and progestins on carbohydrate metabolism as occur in other species (1,22,23). Glucocorticoid "support" in the form of the prednisolone given to one group of treated cats presumably accounted for their clinical well-being, despite evidence for loss of the adrenals' ability to respond to ACTH</div>
<div class="MsoNormal">
stimulation. This would suggest a similar role for megestrol acetate in the other treated group, where adrenal suppression was even more severe. It must be supposed that signs of adrenal insufficiency did not develop after withdrawal of treatment because return of some adrenal reserve was prompt. However, on present understanding, we advise gradual rather than abrupt withdrawal of prednisolone and megestrol acetate treatment, even after therapies as short as one</div>
<div class="MsoNormal">
week. The occurrence of glycosuria, hepatic glycogen deposition, and a reduction in circulating eosinophil numbers in some cats after short term treatment with prednisolone and megestrol acetate is in agreement with these drugs exerting glucocorticoid activity at dose rates employed for therapy of inflammatory dermatoses. Absence of reduction in lymphocyte counts or enzymological changes is consistent with a feline response to glucocorticoids more similar to people</div>
<div class="MsoNormal">
than to dogs.</div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
REFERENCES</div>
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<br /></div>
<div class="MsoNormal">
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<span style="font-size: 8pt;">Gilman AG, Goodman LS, Gilman A, eds. The pharmacological basis of therapeutics. 6th ed. MacMillan Publishing Co, 1980: 1466-1496.</span></div>
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<span style="font-size: 8pt;">2. LIDDLE GW. The adrenals. In: Williams RH, ed. Textbook of endocrinology. 6th ed. Philadelphia: WB Saunders, 1981: 249-292. </span></div>
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<span style="font-size: 8pt;">3. SCOTT DW, MANNING TO, REIMERS TJ. latrogenic Cushing's syndrome in the cat. Feline Practice 1982; 12: 30-36 </span></div>
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<span style="font-size: 8pt;">4. MULLER GH, KIRK RW, SCOTT DW. Small animal dermatology. 3rd ed. Philadelphia: WB Saunders, 1983. </span></div>
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<span style="font-size: 8pt;">5. HALLIWELL RE. Steroid therapy in skin disease. In: Kirk RW, ed. Current veterinary therapy VI. Philadelphia: WB Saunders, 1977: 541-547.</span></div>
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<span style="font-size: 8pt;">6. SCOTT DW. Feline dermatology 1900- 1978: A monograph. J Am Anim Hosp Assoc 1980; 16: 331-459.</span></div>
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<span style="font-size: 8pt;">8. CHASTAIN CB, GRAHAM CL. Adrenocortical suppression in dogs on daily and alternate-day prednisone administration. Am J Vet Res 1979; 40: 936-941.</span></div>
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<span style="font-size: 8pt;">9. KEMPPAINEN RF, THOMPSON FN, LORENZ MD. Use of a low dose synthetic ACTH challenge test in normal and prednisone- treated dogs. Res Vet Sci 1983; 35: 240-242.</span></div>
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<span style="font-size: 8pt;">10. JASPER DE, JAIN NC. The influence of adrenocorticotrophic hormone and prednisolone upon marrow and circulating leukocytes in the dog. Am J Vet Res 1965; 26: 844-850</span></div>
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<span style="font-size: 8pt;">11. DILLON AR, SPANO JS, POWERS RD. Prednisolone induced hematologic, biochemical, and histologic changes in the dog. J Am Anim Hosp Assoc 1980; 16: 831-837.</span></div>
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<span style="font-size: 8pt;">12. BADYLAK SF, VAN VLEET JF. Sequential morphologic and clinicopathologic alterations in dogs with experimentally induced glucocorticoid hepatopathy. Am J Vet Res 1981; 42: 1310-1318</span></div>
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<span style="font-size: 8pt;">13. LEPHERD EE. Technical procedures - haematology. Post Graduate Committee Course Notes, The University of Sydney, 1972: 326.</span></div>
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<span style="font-size: 8pt;">14. REIMERS TJ, COWAN RG, DAVIDSON HP, COLBY ED. Validation for radioimmunoassay for triiodothyronine, thyroxine, and hydrocortisone (cortisol) in canine, feline, and equine sera. Am J Vet Res 1981; 42: 2016-2021.</span></div>
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<span style="font-size: 8pt;">15. FOX JG, BEATTY JO. A case report of complicated diabetes mellitus in a cat. J Am Anim Hosp Assoc 1975; 11: 129-134. 64</span></div>
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<span style="font-size: 8pt;">16. JOHNSTON SD, MATHER EC. Feline plasma cortisol (hydrocortisone) measured by radioimmunoassay. Am J Vet Res 1979; 40: 190-192.</span></div>
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<span style="font-size: 8pt;">17. SCOTT DW, KIRK RW, BENTINCKSMITH J. Some effects of short-term methylprednisolone therapy in normal cats. Cornell Vet 1979; 69: 104-115.</span></div>
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<span style="font-size: 8pt;">18. CUNNINGHAM SK, MOORE A. Mc- KENNA TJ. Normal cortisol response to corticotropin in patients with secondary adrenal failure. Arch Intern Med 1983; 143: 2276-2279.</span></div>
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<span style="font-size: 8pt;">19. HOLUB DA, KATZ FH, JAILER JW. Inhibition by 6-methyl- 17-acetoxyprogesterone of ACTH synthesis and release in the rat. Endocrinology 1961; 38: 173-177.</span></div>
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<span style="font-size: 8pt;">20. BAXTER JD. Glucocorticoid hormone action. Pharmacol Ther 1976; 2: 605-659.</span></div>
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<span style="font-size: 8pt;">21. MIDDLETON DJ, WATSON ADJ. Glucose intolerance in cats given short-term therapies of prednisolone and megestrol acetate. Am J Vet Res 1985; 46: 2623-2625.</span></div>
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<span style="font-size: 8pt;">22. ALTSZULER N, MORRISON A, GOTTLIEB B, BJERKNES C, RATHGEB 1, STEELE R. Alteration by fasting of the effects of methyl-prednisolone on carbohydrate</span></div>
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<span style="font-size: 8pt;">metabolism in the normal dog. Metabolism 1974; 23: 369-374.</span></div>
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<span style="font-size: 8pt;">23. WEIKEL JH Jr. NELSON LW, RENO FE. A four-year evaluation of the chronic toxicity of megestrol acetate in dogs. Toxicol Appl Pharmacol 1975; 33: 414-426.</span></div>
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<span style="font-size: 8pt;">24. FIELDER FG, HOFF EJ, THOMAS GB, TOLKSDORF S, PERLMAN PL CRONIN MTI. A study of the subacute toxicity of prednisolone, methylprednisolone,</span></div>
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<span style="font-size: 8pt;">and triamcinolone in dogs. Toxicol Appi Pharmacol 1959; 1: 305-314.</span></div>
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<span style="font-size: 8pt;">25. ROGERS WA, RUEBNER BH. A retrospective study of probable glucocorticoidinduced hepatopathy in dogs. J Am Vet Med Assoc 1977; 170: 603-606.</span></div>
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<span style="font-size: 8pt;">26. CHRISTOFFERSEN P, POULSEN H,SKEIE E. Focal cell necroses accompanied by infiltration of granulocytes arising during operation. Acta Hepatosplenol 1970; 17:240-245.</span></div>
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<span style="font-size: 8pt;">27. WIENER J, LOUD AV, KIMBERG DV, SPIRO D. A quantitative description of cortisone-induced alterations in the ultrastructure of rat liver parenchymal cells.</span></div>
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<span style="font-size: 8pt;">J Cell Biol 1968; 37: 47-61.</span></div>
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<span style="font-size: 8pt;">28. SWIFT GA, BROWN RH. Surgical treatment of Cushing's syndrome in the cat. Vet Rec 1976; 99: 374-375.</span></div>
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<span style="font-size: 8pt;">29. MEIJER JC, LUBBERINK AAME, GRUYS E. Cushing's syndrome due to adrenocortical adenoma in a cat. Tijdschr Diergeneeskd 1978; 103: 1048-1051. 65</span></div>
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<b><span style="font-size: 16pt;">19) <a href="http://www.ncbi.nlm.nih.gov/pubmed/4083603" style="color: blue; text-decoration: underline; text-underline: single;"><span style="text-decoration: none;">Glucose intolerance in cats given short-term therapies of prednisolone and megestrol acetate.</span></a></span></b></div>
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Middleton DJ, Watson AD.</div>
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Am J Vet Res. 1985 Dec;46(12):2623-5.</div>
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PMID:</div>
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4083603</div>
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[PubMed - indexed for MEDLINE] </div>
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Abstract</div>
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Six cats were each given prednisolone (2 mg/kg of body weight/day) and megestrol acetate (5 mg/cat/day) on separate occasions for 8 days. The drugs induced similar increases in fasting blood glucose concentrations and decreases in glucose excretion rates in the cats. Usually, each cat developed reduced tolerance of an IV glucose load; concomitant fasting hyperglycemia occurred in 3 cats after prednisolone therapy, and in 1 of these 3 cats after megestrol acetate</div>
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<b><span style="font-size: 16pt;">20)<a href="http://www.ncbi.nlm.nih.gov/pubmed/6511591" style="color: blue; text-decoration: underline; text-underline: single;"><span style="text-decoration: none;">Diabetes mellitus and abdominal adenocarcinoma in a jaguar receiving megestrol acetate.</span></a></span></b></div>
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Kollias GV Jr, Calderwood-Mays MB, Short BG.</div>
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J Am Vet Med Assoc. 1984 Dec 1;185(11):1383-6. No abstract available. </div>
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PMID:</div>
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6511591</div>
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[PubMed - indexed for MEDLINE] </div>
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<b><span style="color: blue; font-size: 16pt;">21) Feline miliary eczema: megestrol acetate does not suppress immune responses.</span></b></div>
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Browning MJ, Herbert WJ, White RG.</div>
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Res Vet Sci. 1983 Sep;35(2):245-6.</div>
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PMID: 415771 [PubMed - indexed for MEDLINE] </div>
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Abstract</div>
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Megestrol acetate was found to have no influence on immunological skin and corneal reactivity nor on antibody responses in guinea pigs. Its curative effect in feline miliary eczema is probably not, therefore, the result of interference with the immune response.</div>
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<b><span style="font-size: 16pt;">22) <a href="http://www.ncbi.nlm.nih.gov/pubmed/6298164" style="color: blue; text-decoration: underline; text-underline: single;"><span style="text-decoration: none;">Insulin therapy in cats with diabetes mellitus.</span></a></span></b></div>
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Moise NS, Reimers TJ.</div>
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J Am Vet Med Assoc. 1983 Jan 15;182(2):158-64.</div>
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PMID:</div>
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6298164</div>
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[PubMed - indexed for MEDLINE] </div>
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<h3>
<span style="font-family: "arial"; font-size: 12pt;">Abstract</span></h3>
<span style="font-family: "arial";">Thirteen <span class="highlight">cats</span> with diabetes mellitus were evaluated. Clinical signs included polydipsia, polyuria, polyphagia, lethargy, and weight loss. Results of physical examination included obesity, hepatomegaly, mild seborrhea sicca, muscle wasting, and dehydration. One cat walked plantigrade and was suspected of having a diabetic neuropathy. Persistent hyperglycemia, glucosuria, high liver enzyme activities, hypercholesterolemia, hyperproteinemia, and low electrolyte concentrations were the common laboratory findings. In 3 <span class="highlight">cats</span> diabetes mellitus developed after <span class="highlight">megestrol acetate</span> therapy; 2 of these <span class="highlight">cats</span> required only temporary insulin treatment. In a 3rd cat, which had no history of receiving diabetogenic drug therapy, remission of diabetes mellitus also was observed. Serum insulin and plasma glucose concentrations were determined in 6 <span class="highlight">cats</span> after administration of an intermediate-acting insulin (isophane insulin) and in 3 <span class="highlight">cats</span> after administration of a long-acting insulin (protamine zinc insulin). The insulin concentration peaked 2 to 6 hours after the injection of intermediate-acting insulin and 6 to 12 hours after the injection of long-acting insulin. The lowest glucose concentration was recorded 4 to 8 hours after injection of intermediate-acting insulin, and 6 to 12 hours after injection of long-acting insulin. It was concluded that, although insulin therapy must be adjusted to the individual, the diabetic cat usually requires twice-daily administration of isophane insulin; however, the protamine zinc insulin can be given once daily for satisfactory control.</span><br />
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PMID: 6298164 [PubMed - indexed for MEDLINE] </div>
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<b><span style="font-size: 16pt;">23)<a href="http://www.ncbi.nlm.nih.gov/pubmed/7337916" style="color: blue; text-decoration: underline; text-underline: single;"><span style="text-decoration: none;">The use of megestrol acetate in some feline dermatological problems.</span></a></span></b></div>
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Gosselin Y, Chalifoux A, Papageorges M.</div>
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Can Vet J. 1981 Dec;22(12):382-4.</div>
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PMID: 7337916 [PubMed - indexed for MEDLINE] </div>
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Y. GOSSELIN, A. CHALIFOUX AND M. PAPAGEORGES</div>
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Department of Medicine, School of Veterinary Medicine, University of</div>
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Montreal, P.O. Box 5000, St. Hyacinthe, Qu6bec, Canada J2S 7C6</div>
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SUMMARY</div>
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Twenty-one cats were treated with megestrol acetate because they were showing clinical signs associated with</div>
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one of the following problems: eosinophilic ulcer, eosinophilic plaque, neurodermatitis, endocrine alopecia</div>
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and miliary dermatitis. The dosage schedule was 5 mg orally per day per cat for seven days, then 5 mg every</div>
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three days for 21 days. In all cats, we noted a good improvement of the lesions as soon as treatment was started. In 25% of the patients, one treatment schedule was sufficient to control the skin disease for at least 18 months. In the remaining</div>
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75%, two treatment schedules and/ or a maintenance dosage had to be established. Side effects encountered were</div>
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increased appetite, personality changes and depression.</div>
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I NTRODUCTION</div>
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Megestrol acetate is an oral progestational agent with generally antigonadotrophic properties and without any estrogenic, androgenic and anabolic effects (11,14,25). The drug was introduced to suppress or delay estrus (5,6,8,9), and to arrest pseudopregnancy in the bitch (9). It has also been used in the queen (9,13,21,23). A literature search revealed that</div>
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megestrol acetate is being used for feline dermatological problems (1,3,7, 14,16,20,26,27,28,29). It has been used to control eosinophilic granuloma (1,7,16,20,27,28), feline neurodermatitis (7), miliary dermatits (3,7,14) and feline endocrine alopecia (7). This article is a clinical study of a megestrol acetate regimen used to control the signs of feline ermatological</div>
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problems. </div>
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MATERIALS AND METHODS</div>
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In this study, 21 cats were treated with megestrol acetate' to control or suppress the clinical signs of dermatological diseases cited above. Nine cats were purebreds (Siamese, Himalayan, Persian), male and female were equally represented and their age varied between seven months and 11 years, with an average of 3.5 years. The disease processes, already present from two weeks to 3.5 years (average 1.75 years), had been medicated with different drugs without success before therapy was first started with megestrol acetate. The therapeutic regimen used was as follows: 5 mg per day given orally for the first seven days, then the dosage was reduced to 5 mg every three days for 21 days. At the end of treatment, the cats were reexamined and medication was then adjusted according to the response (lesions still present or absent) and physical state of the patients (treatment was discontinued when side effects were severe). In some</div>
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cases, a dosage of 5 mg every three days was maintained until the lesions regressed. In other cats, the dosage was increased or decreased to find the amount of drug needed to maintain the animal in an asymptomatic state. Whenever the animal was presented again after the initial treatment because of a relapse, then the initial therapeutic regimen was resumed.</div>
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RESULTS</div>
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Eosinophilic Ulcer (Rodent Ulcer) Two cats were treated for well demarcated lesions of upper lip, characteristic of this skin disease. In one cat, the lesions disappeared completely after the first treatment, while it took two treatments, one month part, to eliminate the lesions from the second cat. No relapse of the lip lesions has occurred 18 months after treatment. It</div>
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is important to note that the second cat had to be put on a maintenance dosage of 5 mg weekly or biweekly to control the clinical signs of eosinophilic plaque. This latter condition worsened when medication was discontinued, while the lip ulcer never reappeared </div>
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(Table I).</div>
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'<shape coordsize="21600,21600" id="_x0000_s1025" style="height: 269.25pt; width: 364.5pt;" type="#_x0000_t75"> <imagedata cropbottom=".1875" cropright="21135f" croptop=".1875" o:title="" src="Megestrol%20Acetate%20Studies%20on%20PubMed_files/image019.png"></imagedata></shape></div>
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Eosinophilic Plaque In six cats a diagnosis of eosinophilic plaque was established after finding circular, raised, Erythematous and exudative lesions associated with alopecia and pruritus. The distribution pattern varied from one subject to the other, but most lesions were found on the abdominal wall. All cats responded well to megestrol acetate,</div>
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but one cat did not develop any more skin lesions after the initial treatment was stopped. In the remaining five</div>
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cats, the prescription had to be repeated two to seven months after the first visit and four cats are presently on</div>
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a maintenance dosage of 5 mg once or twice a week (Table I).</div>
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Feline Neurodermatitis</div>
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Seven cats were examined and showed skin lesions that could be associated with this disease; of these four were purebreds. Single, erythematous lesions with complete or partial alopecia were associated with pruritus and excessive licking. In all cats a good response was noticed with the megestrol acetate regimen. In two cats, no relapse was noted six to 18 months after treatment. In the five other animals a maintenance dosage of 5 mg once or twice a week had to be established (Table I).</div>
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Feline Endocrine Alopecia </div>
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Two cats with symmetrical and bilateral lesions of partial to complete m = male (c) = castrated or spayed</div>
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alopecia of the abdominal and inner thigh area were treated with megestrol acetate. No noticeable inflammation of the skin was seen and the owners did not report excessive pruritus. The two cats showed a marked improvement while on medication, but the skin lesions reappeared two to four weeks after therapy was discontinued. These cats had to be put on a maintenance dosage of 5 mg once or twice weekly (Table I).</div>
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Miliary Dermatitis In three of four cats with clinical signs of this skin disease, i.e. partial alopecia, erythema, hemorrhagic</div>
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crusts, and small papules associated with pruritus; lesions reappeared one or two months after discontinuing the drug. In these cats a maintenance dosage of 5 mg had to be established to control the skin lesions. In one cat, relapse occurred 18 months after the initial treatment (Table I). In two of those cases, before a megestrol acetate treatment was started, a flea control therapy program had been established without any good results.</div>
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D I S C U S S IO N</div>
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Many types of therapy have been advocated to control these skin diseases in the cat. For eosinophilic ulcer and/ or plaque, some authors recommend: surgical excision (26) or cryosurgery (10,15,17,18,30) when dealing with single lesions. Others suggest the use of: radiation therapy (4,24,26), levamisole or thiabendazole (12,19), lincomycin (10), glucocorticoids (10,24,26) and progestational compounds , like megestrol acetate (26,27,28,29) and medroxyprogesterone acetate (26). Progestational compounds seem to be the drugs of choice for the treatment</div>
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of miliary dermatitis (2,3,14,22,26). Many therapeutic regimens have been used for the treatment of feline neurodermatitis. Glucocorticoids, tranquilizers, vitamin-mineral supplements, radiation therapy, foul tasting ointments and Elizabethan collars have been used (27). Phenobarbital and diazepam have also been advocated and are effective in certain cases</div>
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(27). Progestational drugs, like megestrol acetate, given in large doses seem to control the skin lesions associated with this condition (26). Combined androgen-estrogen injections or progestational drugs have been used for the treatment of feline endocrine alopecia (26). Initially a dosage of 2.5 mg per day per cat was randomly chosen. However, it became clear that this therapeutic regimen was insufficient and the initial dosage was doubled to 5 mg. A literature review had shown a wide range in the dose and dosage schedules used by various authors (14,16,20,22, 26). A good improvement of the lesions was noted in all cats, after the initial treatment. In 25% of the patients one treatment regimen was sufficient to control the skin disease for at least 18 months. In the remaining 75%, two treatment regimens and/or a maintenance</div>
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dosage had to be established. Some of the side effects reported with the use of megestrol acetate are: increased appetite, personality changes, pyometra, mammary hyperplasia, transient diabetes mellitus, poor reproductive performance in the male, local alopecia and/ or cutaneous atrophy (I 1,14,21,26). The most frequently seen side effects in our study were: increased appetite, personality changes and depression. In one case, iatrogenic transient diabetes mellitus was diagnosed. Finally, it must be emphasized that megestrol acetate is not licensed for use in the cat in Canada.</div>
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REFERENCES</div>
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1. ALLEN, L.S. Eosinophilic granuloma treatment (megestrol). Feline Practice 7: 4344. 1977.</div>
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2. ASPINAL, K.W. and J.M. EVANS. The use of megestrol acetate in the treatment of military eczema in the cat. Vet. Rec. 88: 374. 1971.</div>
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3. ASPINAL, K.W. and W.T. TURNER. Feline military dermatitis. J. small Anim. Pract. 13: 709-710. 1972.</div>
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4. BIERY, D.N. Radiation therapy in dermatology. In Current Veterinary Therapy VI. Small Animal Practice. pp. 527-528. Philadelphia: W.B. Saunders. 1977.</div>
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5. BURKE, T.J. and H.A. REYNOLDS. Megestrol acetate for estrus postponement in the bitch. J. Am. vet. med. Ass. 167: 285-287.1975.</div>
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6. CHAINEY, D., A.M. McCONBREY and J.M. EVANS. The excretion of megestrol acetate by beagle bitches. Vet. Rec. 86: 287-288.1970.</div>
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7. CHESNEY, c.i. The response to progestagen treatment of some diseases of cats. J. small Anim. Pract. 17: 3544. 1976.</div>
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8. cox, J.E. Progestogens in bitches: a review. J. small Anim. Pract. 11: 759-778. 1970.</div>
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9. GERBER, H.A. and F.G. SULMAN. The effects of methyloestrenalone on oestrus, pseudopregnancy, vagrancy, satyriasis and squirt-Nord VetMed. 29: 287-291. 1977 1092. 1964.</div>
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10. GRIFFITHS, B.C.R. Eosinophilic granuloma (rodent ulcer) in the cat. Vet. Rec. 100: 159. 1977.</div>
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11. HART, B.L. Behavioral effects of long-acting progestins. Feline Practice 4: 8-11. 1974.</div>
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12. HESS, P.W. and E.G. MacEWEN. Feline eosinophilic granuloma. In Current Veterinary Therapy VI. Small Animal Practice. pp. 534-537. Philadelphia: W.B. Saunders. 1977.</div>
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13. HOUDESHELL, J.W. and P.N. HENNESSEY. Megestrol acetate for the control of estrus in the cat. Vet. Med. small Anim. Clin. 72: 1013-1017. 1977.</div>
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14. HOUDESHELL, J.E., P.W. HENNESSEY and H.B. BIGBEE. Treatment of feline miliary dermatitis with megestrol acetate. Vet. Med. Small Anim. Clin. 72: 573-575. 1977.</div>
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15. KRAHWINKEL, JR., D.J., D.L. MERKLEY and D.R. HOWARD. Cryosurgical treatment of cancerous and non-cancerous diseases of dogs, horses and cats. J. Am. vet. med. Ass. 169: 201-207. 1976.</div>
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16. KRISTENSEN, s. and A. FLAGSTAD. Behandling of eosinofilt granulom type II has kat med megestrol acetat. Dansk Veterinaertidsskrift 63: 665-669. 1979.</div>
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17. LANE, J.G. Practical cryosurgery: an introduction for small animal clinicians. J. small Anim. Pract. 15: 715-725. 1974.</div>
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18. LANE, J.G. and T.J. GRUFFYDD-JONES. Eosinophilic granulomas in cats. Vet. Rec. 100: 251. 1977.</div>
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19. MacEWEN, E.G. General concepts of immunotherapy of tumors. J. Am. anim. hosp. Ass. 12: 363-373. 1976.</div>
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20. McDOUGAL, B.J. Eosinophilic granuloma complex in the cat. Feline Practice 7: 27-30. 1977.</div>
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21. OEN, E.O. The oral administration of megestrol acetate to postpone oestrus in cats. Nord VetMed. 29: 287-291. 1977.</div>
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22. Panel report. Skin disease in cats. Mod. vet. Pract. 61: 715-716. 1980. </div>
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23. REMFRY, J. Control of feral cat populations by longterm administration of megestrol acetate. Vet. Rec. 103: 403-404. 1978.</div>
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24. SCOTT, D.W. Observations on the eosinophilic granuloma complex in cats. J. Am. anim. hosp. Ass. 11: 261-70.1975.</div>
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25. SCOTT, D.W. Miliary eczema in the cat: a review. Am. anim. hosp. Ass. Proc. 43: 145-152. 1976.</div>
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26. SCOTT, D.W. Feline dermatology 1900-1978:a monography. J. Am. anim. hosp. Ass. 16:303-459. 1980.</div>
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27. SUNDELL, J. Eosinophilic granuloma treatment. Feline Practice 5: 4. 1975.</div>
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28. SUNDELL, j. Eosinophilic granuloma treatment (in the cat). Feline practice. 6: 25.1976.</div>
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29. TURNER, T. Eosinophilic granuloma in cats. Vet. Rec. 100: 327. 1977.</div>
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30. WILLENSE, A. and A.A.M.E. LUBBERINK. Cryosurgery of eosinophilic ulcers in cats.Tijdschr. Diergeneesk. 103: 1052-1056.1978.</div>
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<b><span style="font-size: 16pt;">24)<a href="http://www.ncbi.nlm.nih.gov/pubmed/6280517" style="color: blue; text-decoration: underline; text-underline: single;"><span style="text-decoration: none;">Adrenocortical suppression in cats given megestrol acetate.</span></a></span></b></div>
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Chastain CB, Graham CL, Nichols CE.</div>
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Am J Vet Res. 1981 Dec;42(12):2029-35.</div>
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PMID:</div>
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6280517</div>
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[PubMed - indexed for MEDLINE] </div>
<h3>
<span style="font-family: "arial"; font-size: 12pt;">Abstract</span></h3>
<span class="highlight"><span style="font-family: "arial";">Megestrol acetate</span></span><span style="font-family: "arial";"> was given orally to 8 <span class="highlight">cats</span> at a dose of 2.5 mg every other day for 2 weeks and to 8 <span class="highlight">cats</span> at a dose of 5.0 mg every day for 2 weeks. Four <span class="highlight">cats</span> were designated nontreated controls. Pre-ACTH-stimulated plasma concentrations of cortisol (hydrocortisone) and ACTH-stimulated cortisol and tolerance to large-dose glucose infusion (IV) were determined on each of the 20 <span class="highlight">cats</span> given <span class="highlight">megestrol acetate</span>. <span class="highlight">Cats</span> were restrained with acepromazine maleate and ketamine hydrochloride during blood sample collection and large-dose glucose infusion. Adrenocortical function and tolerance to large-dose glucose infusion were reevaluated for 4 weeks--after 1st and 2nd weeks of <span class="highlight">megestrol acetate</span> treatment of the treated groups, and after 1st and 2nd weeks when treatment was stopped (i.e., experiment weeks 3 and 4). Each week a cat from the control group and 2 <span class="highlight">cats</span> from the 2 treated groups were selected to determine the changes occurring during the experiment for that week; after collection of plasma samples, each week's 5 selected <span class="highlight">cats</span> were euthanatized and necropsied. Significant impairment of adrenocortical function and alteration of adrenocortical morphology occurred with both treated groups. The most severe adrenocortical alterations occurred in the <span class="highlight">cats</span> 1 week after <span class="highlight">megestrol acetate</span> was no longer given (i.e., experiment week 3). <span class="highlight">Megestrol acetate</span>-induced adrenocortical suppression contributed to the death of 1 cat. It was concluded that if stress occurs to <span class="highlight">cats</span> on treatment or soon after treatment with <span class="highlight">megestrol acetate</span>, glucocorticoids should be supplemented. The effects of <span class="highlight">megestrol acetate</span> on glucose tolerance were overshadowed by the unforeseen intolerance caused by chemical restraint with acepromazine maleate and ketamine hydrochloride.</span><br />
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PMID: 6280517 [PubMed - indexed for MEDLINE] </div>
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<b><u><span style="color: blue; font-size: 16pt;">25) [The use of megestrol acetate to stop urine spraying in castrated male cats (author's transl)].</span></u></b></div>
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Chalifoux A, Gosselin Y.</div>
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Can Vet J. 1981 Jul;22(7):211-2. French. </div>
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PMID: 7340918 [PubMed - indexed for MEDLINE] </div>
<h3>
<span style="color: windowtext; font-family: "arial";">Abstract</span></h3>
<span style="font-family: "arial";">The use of <span class="highlight">megestrol acetate</span> to stop urine spraying in castrated male <span class="highlight">cats</span> Four castrated male <span class="highlight">cats</span> were treated with <span class="highlight">megestrol acetate</span> because they were showing signs of urine spraying. The dosage used was 5 mg a day for seven days followed by 5 mg every three days for 21 days. The treatment did not exceed one month. Treatment was successful in three of the four animals with this therapeutic regime. A relapse was noticed one year after the initial treatment in two of these <span class="highlight">cats</span>. Treatment was resumed in one case, while in the other case spontaneous regression of urine spraying occurred. No relapse have been reported after six months. Other methods of treatment used to suppress this undesirable behavior are also discussed. ( full text available, in French.)</span><br />
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<b><span style="color: blue; font-size: 16pt;">26)<u><a href="http://www.ncbi.nlm.nih.gov/pubmed/7440346" style="color: blue; text-decoration: underline; text-underline: single;">Objectionable urine spraying and urine marking in cats: evaluation of progestin treatment in gonadectomized males and females.</a></u></span></b></div>
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<u>Hart BL.</u></div>
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J Am Vet Med Assoc. 1980 Sep 15;177(6):529-33.</div>
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PMID: 7440346 [PubMed - indexed for MEDLINE] </div>
<h3>
<span style="font-family: "arial"; font-size: 12pt;">Abstract</span></h3>
<span style="font-family: "arial";">The increasing use of long-acting progestins to treat objectionable urine spraying and urine marking in gonadectomized <span class="highlight">cats</span> prompted a survey of the comparative effectiveness of the injectable medroxyprogesterone <span class="highlight">acetate</span> (MPA) and the orally administered <span class="highlight">megestrol acetate</span> (MA). Both drugs were successful, overall, in about 1/3 of the patients. However, the proportion with favorable response was higher for males (48%) than for females (13%) and was higher for <span class="highlight">cats</span> from single-cat homes (50%) than for <span class="highlight">cats</span> from multi-cat homes (18%). Because of the reportedly higher frequency of depression and increased appetite following MA treatment, when compared with MPA treatment, it is recommended that MPA be used initially for routine treatment of these behavioral problems. The survey revealed that if MPA proves ineffective, subsequent treatment with MA can be expected to yield favorable results in some of these patients.</span><br />
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<b><span style="color: blue; font-size: 16pt;">27) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/427709" style="color: blue; text-decoration: underline; text-underline: single;">A hyperglycemia-glucosuria syndrome in cats following megestrol acetate therapy.</a></u></span></b></div>
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Pukay BP. </div>
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Can Vet J. 1979 Apr;20(4):117. No abstract available. </div>
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PMID: 427709 [PubMed - indexed for MEDLINE] </div>
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A Hyperglycemia-Glucosuria Syndrome in Cats Following Megestrol Acetate Therapy</div>
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DEAR SIR:</div>
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Recently, megestrol acetate has been associated with the appearance of clinical signs of transitory diabetes mellitus in the cat (2,5). We would like to expand on Dr. Hutclison's letter (Can. vet. J. 19: 324. 1978) and describe in greater detail the three cases in which hyperglycemia and glucosuria appeared after megestrol acetate therapy for various skin conditions was instituted. </div>
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Case I - An 18 year old male, neutered, domestic long-haired cat with miliary dermatitis was treated with an alternate day dosage of 5 mg megestrol acetate.' There was a history of prolonged corticosteroid therapy as well as diabetes mellitus which had regressed spontaneously one year previously. After two weeks of treatment, polydipsia and polyuria was reported and urine reacted positively to a test for glucosuria.2 A blood test for hyperglycemia was also positive.3 The cat died within three days, in spite of insulin and supportive therapy.</div>
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Case 2 - A ten year old, male, neutered, domestic short-haired cat with miliary dermatitis was treated initially with 30 mg methlylprednisolone acetate4 intramuscularly. Two months later he was treated with 5 mg megestrol acetate on alternate days. Polydipsia, polyuria, polyphagia and weight loss appeared within ten days. The cat was stabilized on insulin and megestrol acetate therapy was continued. Within a month, signs of hypoglycemia appeared and therapy was stopped. The cat has remained normal since. </div>
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Case 3 - A three year old, male, neutered cat was treated for an eosinophilic granuloma with an intralesional injection of 20 mg methylprednisolone acetate. When healing failed to occur, surgical excision was performed. When the granuloma recurred, the cat was placed on 2.5 mg prednisone5 daily and 100 mg chloramphenicol ' daily. One week later, surgical</div>
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excision was again attempted and, when this failed, the cat was then treated with 5 mg megestrol acetate on alternate day dosage. The lesion was also injected with 0.4 cc triamcinolone. The treatment was repeated again two weeks later and the megestrol acetate continued. The cat was admitted again after two weeks for polyuria, polydipsia and an elevated temperature of 40.30C. The cat was stabilized with insulin and megestrol acetate therapy was discontinued. The insulin dose was gradually reduced over ten days and the cat is doing well. Whether or not megestrol acetate can precipitate</div>
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signs of transitory diabetes mellitus remains unproven. In all these cases blood and urine tests were positive for glucose. Unfortunately, no glucose tolerance tests were done. Megestrol acetate is contraindicated in cats with diabetes (I ) and side effects of the drug include polydipsia, polyuria, weight increase, thickened hair coat, personality changes and endometritus (1,3,4). We have successfully used megestrol acetate in the treatment of selected dermatological cases in</div>
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cats, particularly those with miliary dermatitis, eosinoplilic lick granulomas, including rodent ulcers, and hormonal alopecias. It has also been used with some success in behavioural (territorial) urine marking in neutered and unneutered cats. If megestrol acetate therapy is to be used, we would suggest that the owner be made aware of the possible side effects and, if polydipsia and/or polyuria occur, a routine urinalysis, including a test for glucosuria, should be performed. If</div>
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positive, therapy should be discontinued or the dosage levels reduced.</div>
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Yours truly,</div>
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B.P. PUKAY, B.A., D.V.M.</div>
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1814 Bank Street Ottawa, Ontario K! V 7 Y6</div>
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References</div>
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1. HALLIWELL, R.E. Steroidal therapy in skin disease. In Current Veterinary Therapy VI. W.E. Kirk, Editor.</div>
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pp. 541-547. Toronto: W.B. Saunders. 1977.</div>
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2. HUTCHISON, J.A. Progestogen therapy for certain skin diseases of cats. Can. vet. J. 19: 324. 1978.</div>
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3. OEN, E.O. Megestrol acetate for estrus suppression in cats. Nord. Vet. Med. 29: 287-291. 1977.</div>
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4. SCOTT. D.W. Miliary eczema in the cat: a review. Proc. Am. anim. hosp. Ass. 43: 145-152. 1976.</div>
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5. WERNER, R. Letter to the editor. Feline Pract. 8: 4. 1978.</div>
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<b><span style="font-size: 16pt;">28) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/726206" style="color: blue; text-decoration: underline; text-underline: single;">Control of feral cat populations by long-term administration of megestrol acetate.</a></u></span></b></div>
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Remfry J.</div>
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Vet Rec. 1978 Oct 28;103(18):403-4. No abstract available. </div>
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PMID: 726206 [PubMed - indexed for MEDLINE] </div>
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<b><span style="font-size: 16pt;">29)<u><a href="http://www.ncbi.nlm.nih.gov/pubmed/636220" style="color: blue; text-decoration: underline; text-underline: single;">Megestrol acetate and appetite gain.</a></u></span></b></div>
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Cooper JH.</div>
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Vet Rec. 1978 Jan 14;102(2):45. No abstract available. </div>
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PMID: 636220 [PubMed - indexed for MEDLINE] </div>
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<b><span style="font-size: 16pt;">30) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/595306" style="color: blue; text-decoration: underline; text-underline: single;">Megestrol acetate and appetite gain.</a></u></span></b></div>
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Donald SG.</div>
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Vet Rec. 1977 Dec 3;101(23):472. No abstract available. </div>
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PMID: 595306 [PubMed - indexed for MEDLINE] </div>
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<b><span style="font-size: 16pt;">31)<u><a href="http://www.ncbi.nlm.nih.gov/pubmed/896408" style="color: blue; text-decoration: underline; text-underline: single;">The oral administration of megestrol acetate to postpone oestrus in cats.</a></u></span></b></div>
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Oen EO.</div>
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Nord Vet Med. 1977 Jun;29(6):287-91.</div>
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PMID: 896408 [PubMed - indexed for MEDLINE] </div>
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<h3>
<span style="font-family: "arial"; font-size: 12pt;">Abstract</span></h3>
<span style="font-family: "arial";">During 1974, <span class="highlight">megestrol acetate</span> tablets were distributed to 397 cat owners in the Oslo district for use as an oestrus suppressing agent in <span class="highlight">cats</span>. A weekly dose of 2.5 mg <span class="highlight">megestrol acetate</span> was given for at least 30 weeks. Treatment was carried out according to plan in 244 <span class="highlight">cats</span>. Results are shown in Table I. The course of birth was abnormal in two <span class="highlight">cats</span> which were pregnant before the trial began. Pregnancy was not registered in any of the remainder. Heat was observed during the period of treatment in 21 of the 244 <span class="highlight">cats</span> treated according to plan without pregnancy being registered. As regards side effects of the preparation, increased appetite, weight increase and changes of temperament were the most pronounced. One cat developed pyometra after three years of treatment with the preparation.</span><br />
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<span style="font-size: 14pt;">32) </span><b><span style="font-size: 16pt;"><a href="http://www.ncbi.nlm.nih.gov/pubmed/586070" style="color: blue; text-decoration: underline; text-underline: single;">Megestrol acetate for control of estrus in the cat.</a></span></b></div>
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Houdeshell JW, Hennessey PW.</div>
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Vet Med Small Anim Clin. 1977 Jun;72(6):1013-7. No abstract available. </div>
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PMID: 586070 [PubMed - indexed for MEDLINE] </div>
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NO ABSTRACT GIVEN</div>
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<b><span style="color: blue; font-size: 16pt;">33)<u>Non-neoplastic memmary hypertrophy in the cat associated either with pregnancy or with oral progestagen therapy.</u></span></b></div>
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Hinton M, Gaskell CJ.</div>
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Vet Rec. 1977 Apr 2;100(14):277-80.</div>
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PMID: 871052 [PubMed - indexed for MEDLINE] </div>
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<span style="font-family: "arial"; font-size: 12pt;">Abstract</span></h3>
<span style="font-family: "arial";">Nine cases of mammary glandular hypertrophy in the cat are described. Three cases occurred in pregnant queens aged between six and eight months and one in an aged non-pregnant queen. The other cases were in neutered animals which had been treated with <span class="highlight">megestrol acetate</span> for periods of between 14 months and five years. The pregnant queens were spayed and their mammae returned to normal; in the other <span class="highlight">cats</span> the affected mammary glands were removed surgically. No recurrence occurred in seven <span class="highlight">cats</span> in which adequate follow-up information was available. The importance of differentiating this benign lesion from mammary neoplasia is discussed.</span><br />
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<span style="font-family: "arial"; font-size: 12pt;">PIP: </span></h4>
<span style="font-family: "arial";">This report is based on data from 9 <span class="highlight">cats</span>: 4 were queens, of which 3 were pregnant, 5 were neutered <span class="highlight">cats</span>, 2 male and 3 female, which had been receiving <span class="highlight">megestrol acetate</span> (MA) for the treatment of miliary eczema for periods of 14 months to 5 years. In all <span class="highlight">cats</span> the condition was painless. There was gross enlargement of the mammary glands. In 2 cases the skin over the glands was ulcerated. Ovaro-hysterectomy was done on the 3 pregnant queens. The other 6 cases were diagnosed from biopsy specimens. The lesions were then excised. Following ovaro-hysterectomy, the lesions softened and gradually regressed. In the neutered <span class="highlight">cats</span> no recurrence occurred during the follow-up period. Histological studies showed only benign changes with fibroglandular hyperactivity. An excess of progesterone has been suggested as a cause. The MA therapy cannot be excluded as a cause in some cases. Differentiation of this condition from adenocarcinoma is important. The distinction may be made by histological study of biopsy specimens.</span><br />
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PMID: 871052 [PubMed - indexed for MEDLINE] </div>
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<b><span style="font-size: 16pt;">34)<u><a href="http://www.ncbi.nlm.nih.gov/pubmed/585519" style="color: blue; text-decoration: underline; text-underline: single;">Treatment of feline miliary dermatitis with megestrol acetate.</a></u></span></b></div>
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Houdeshell JW, Hennessey PW, Bigbee HB.</div>
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Vet Med Small Anim Clin. 1977 Apr;72(4):573-5. No abstract available. </div>
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PMID:</div>
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585519</div>
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[PubMed - indexed for MEDLINE] </div>
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<b><span style="font-size: 16pt;">35) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/64332" style="color: blue; text-decoration: underline; text-underline: single;">Contraceptive steroid toxicology in the Beagle dog and its relevance to human carcinogenicity.</a></u></span></b></div>
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Owen LN, Briggs MH.</div>
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Curr Med Res Opin. 1976;4(5):309-29.</div>
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PMID: 64332 [PubMed - indexed for MEDLINE] </div>
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Abstract</div>
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Problems associated with the use of the Beagle dog in chronic toxicological studies of contraceptive steroids are described. A short review is presented on the occurrence of spontaneous tumours in dogs and in bitches of various breeds. The current status of knowledge of canine reproductive hormones and endocrinology is outlined, together with effects of contraceptive steroids. The pathology and histological classification of spontaneous and induced mammary neoplasia in the dog is discussed and compared with breast cancer in women. A series of recommendations are included for future research in this field which it is hoped may resolve some of the outstanding issues and lead to a more suitable toxicological model for contraceptive steroids.</div>
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PIP: </div>
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Many scientists have criticized the mandatory use of dogs for studies of the chronic toxicity of synthetic steroidal contraceptive hormones. The estimated annual incidence rates for cancer of all sites in dogs is 381.2/100,000 dogs. The estimated relative risk (R) value for the occurrence of tumors in the Beagle breed is 0.9; for malignant tumors, the R value in the Beagle is 0.8. A review of the hormonal potency of various contraceptive steroids in the Beagles indicates that progestogenic compounds generally produce a much lower progestational activity in dogs than in women, and the predominant hormonal action of norethisterone in dogs is estrogenicity rather than progestogenicity. This weak activity for the canine species may account for some of the toxicological findings for norethisterone and related compounds in the Beagle. It is also possible that there are species differences in the relative affinities of estrogen and progesterone receptors for contraceptive steroids. Studies on long-term administration to female Beagle dogs suggest that the nodules found in the mammary gland are not histologically comparable to mammary tumors found in the human female although there is a superficial morphological resemblance to some forms of human mammary dysplasia. Several authors suggest that the results of testing progestational compounds in Beagles are unlikely to be indicative of a potential hazard to the human female. In testing megestrol acetate, it is suggested that the unique sensitivity of the canine females to megestrol acetate is exemplified by intense mammary development at dose levels 10 times the human oral contraceptive level. In contrast, daily dose levels of 500 mg/day in women as a palliative for endometrial cancer have been used with no serious side effects or mammary enlargement. Also the canine mammary gland produces certain pathological changes following administration of natural or synthetic progesterones in a way not readily seen in other species. Possible alternative models (cat, pig) for contraceptive steroid toxicological studies and recommendations for future research are discussed.</div>
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PMID: 64332 [PubMed - indexed for MEDLINE] </div>
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<b><span style="font-size: 16pt;">36) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/1146167" style="color: blue; text-decoration: underline; text-underline: single;">Letter: Oral progestagens in cats.</a></u></span></b></div>
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Findlay MA.</div>
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Vet Rec. 1975 May 3;96(18):413. No abstract available. </div>
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PMID: 1146167 [PubMed - indexed for MEDLINE] </div>
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No abstract given</div>
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<b><span style="font-size: 16pt;">37) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/51808" style="color: blue; text-decoration: underline; text-underline: single;">Reproductive and behavioral control in the male and female cat with progestins: long-term field observations in individual animals.</a></u></span></b></div>
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Jöchle W, Jöchle M.</div>
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Theriogenology. 1975 May;3(5):179-85. </div>
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No abstract available. </div>
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<b><span style="font-size: 16pt;">38) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/4130190" style="color: blue; text-decoration: underline; text-underline: single;">Physiologic, pathologic and therapeutic roles of progestins in domestic animals.</a></u></span></b></div>
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Stabenfeldt GH.</div>
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J Am Vet Med Assoc. 1974 Feb 1;164(3):311-7. Review. No abstract available. </div>
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PMID:</div>
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4130190</div>
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<b><span style="font-size: 16pt;">39) <u><a href="http://www.ncbi.nlm.nih.gov/pubmed/5102613" style="color: blue; text-decoration: underline; text-underline: single;">Use of megestrol acetate in the treatment of miliary eczema in the cat.</a></u></span></b></div>
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Turner WT.</div>
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Vet Rec. 1971 Mar 20;88(12):315-6. No abstract available. </div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-14226885780787698082018-07-20T08:17:00.000-07:002018-07-20T14:15:41.345-07:00Megestrol acetate research from PubMed - chart<div class="MsoNormal">
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<table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" id="table1" style="border-bottom: medium none; border-collapse: collapse; border-left: medium none; border-right: medium none; border-top: medium none; margin-left: -3.95pt;"><tbody>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Ref </span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">#</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;"># </span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">cats</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Age /sex</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">of cat</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Reason</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Prescribed</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">MA</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage & length of treatment w/ MA</span></b></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif;">Side effects</span></b></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">2</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">1 cat </span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">12 year old Intact female Siamese</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Birth control</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage not given – given intermittently over 10 years</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Benign growths in uterus</span></div>
</td></tr>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">3</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Number of cats not given</span></div>
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<br /></div>
<div class="MsoNormal">
<br /></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Survey of insured pet owners. </span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Diabetes occurred in 1 of 230 cats in survey – noted that male cats treated with MA had “significantly higher risk ” for diabetes. </span></div>
</td></tr>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">5</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">1 cat </span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">1.5 </span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">year old male</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Chin sores</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">See ‘Side Effects” column.</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="color: blue;"><span style="font-family: "arial" , "helvetica" , sans-serif;">MA info. in blue </span></span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Other meds in black</span></div>
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<span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Symptoms in green</span></span></div>
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<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Symptoms after MA treatment in bold green</span></span></b></div>
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<span style="background: #ffff99;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Time line in yellow</span></span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Prescribed topical cleansing; oral orbifloxacin 2.2 mg/kg bodyweight daily for 14 days and</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">oral prednisone (generic), 1 mg/kg BW daily for 4 days.</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;"><span style="background: #ffff99;">Day 30</span> <span style="color: teal;">- Same sore – two more</span></span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">methylprednisolone acetate 4 mg/kg BW, sub q administered. A hypoallergenic food trial was commenced.</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"><span style="background: #ffff99;">Day 38</span> <span style="color: #339966;">still had sores – returned to vet</span></span></div>
<div class="MsoNormal">
<span style="color: blue;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Prescribed megestrol acetate 1 mg/kg BW daily for 5 days, and then 0.5 mg/kg BW twice weekly for 21 days.</span></span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">prescription was refilled 33 days later, so that the cat received <span style="color: blue;">1 mg/kg BW for 2 days followed by 0.5 mg/kg BW, for 16 days</span></span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"><span style="background: #ffff99;">Day 96</span> –(58 days after<b> </b>MA prescribed<b>)<span style="color: #339966;"> returned</span></b></span></div>
<div class="MsoNormal">
<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">All 6 breasts swollen</span></span></b></div>
<div class="MsoNormal">
<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Mastectomy of right mammary gland and biopsy of right groin lymph node. Right gland showed benign fibrous tumor </span></span></b></div>
<div class="MsoNormal">
<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">and neutrophils (white blood cells indicating infection) suggesting breast infection. The right groin lymph node had no microscopic organ or tissue damage.</span></span></b></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Rechecked 10 d (<span style="background: #ffff99;">day 106</span>) and 15 d (<span style="background: #ffff99;">day 111</span>) after surgery, that is, 68 d and 73 d after initiation of MA treatment.</span></div>
<div class="MsoNormal">
<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Rest of mammary glands had regressed slightly, but the left groin mammary gland had enlarged slightly.</span></span></b></div>
<div class="MsoNormal">
<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Came in 7 d later (<span style="background: #ffff99;">day</span> <span style="background: #ffff99;">118</span>)for inappetence (80 d after initiation of megestrol acetate treatment).</span></span></b></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"><b><span style="color: #339966;">Temperature slightly above normal and 5% dehydrated. Another chin sore. Left groin mammary gland was ulcerated, swollen, warm, painful to touch, and asymmetrically enlarged to 4 cm in diameter. A CBC count showed a mild leukocytosis (increased white blood cells) and mild neutrophilia (increased white blood cells.) A presumptive diagnosis of superficial mastitis (breast infection) was made.</span></b><span style="color: #339966;"> </span>The cat received trimethoprim-sulfadiazine, 35 mg/kg BW, Sub q 1X daily for 3 days, and sub q meloxicam , 0.02 mg/kg BW, and lactated Ringer's solution, 60 to 120 mL, 1X daily for the next 3 days. <b><span style="color: #339966;">Temperature returned to normal. When the cat's skin lesions returned the owner did not wish to pursue further diagnostic tests and elected to euthanize the cat. A necropsy was not performed.</span></b></span></div>
<div class="MsoNormal">
<br /></div>
</td></tr>
</tbody></table>
<span style="font-family: "arial"; font-size: 12pt;"><br clear="all" style="page-break-before: always;" /><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></span><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span><br />
<div class="MsoNormal">
<br /></div>
<br />
<table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" id="table2" style="border-bottom: medium none; border-collapse: collapse; border-left: medium none; border-right: medium none; border-top: medium none; margin-left: -32pt;"><tbody>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">11</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">8 cats </span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Eye infection</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage not</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">None Reported – successfully treated infection</span></div>
</td></tr>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal" style="margin-left: -9.35pt; text-indent: -37.4pt;">
<span style="font-family: "arial" , "helvetica" , sans-serif;">1212</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">12</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">17 pre-pubescent spayed/neutered kittens </span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">in study</span></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">5 ---------> </span></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">5 -----------></span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
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<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"> </span><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Spayed/</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">neutered kittens</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Spayed/</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">neutered kittens</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Study</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">5</span><span style="font-family: "arial" , "helvetica" , sans-serif;"> mg 2X a week for 12 or 13 weeks then 2.5 mg 1X week for 12 weeks then no ma for 12 weeks</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">15 mg 2X a week for 12 or 13 weeks then 2.5 mg 1X week for 12 weeks then no ma for 12 weeks</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal" style="margin-right: -16.5pt;">
<br /></div>
<div class="MsoNormal" style="margin-right: -16.5pt;">
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<div class="MsoNormal" style="margin-right: -16.5pt;">
<br /></div>
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<br /></div>
<div class="MsoNormal" style="margin-right: -16.5pt;">
<br /></div>
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<br /></div>
<div class="MsoNormal" style="margin-right: -16.5pt;">
<br /></div>
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<br /></div>
<div class="MsoNormal" style="margin-right: -16.5pt;">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Uterine horns increased in length</span></div>
<div class="MsoNormal" style="margin-right: -16.5pt;">
<span style="font-family: "arial" , "helvetica" , sans-serif;">and diameter. Endometrium became deeply folded. Enlargement of glandular epithelium and production of glycogen by the glandular cells. One cat developed pyometra. During 12 weeks without ma proliferate</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">d endometrium regressed considerably </span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal" style="background: #ffff99;">
<span style="font-family: "arial" , "helvetica" , sans-serif;">1 case pyometra </span><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></div>
<div class="MsoNormal" style="margin-right: -16.5pt;">
<br /></div>
</td></tr>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<br /></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">5 -----------></span></div>
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<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">2 -----------></span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Spayed/</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Neutered</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">kittens</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">kittens</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<br /></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">No treatment – served as controls</span></div>
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<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">2.5 mg weekly for 6 weeks</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<br /></div>
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<br /></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">“Sufficient to induce similar changes” - - not clear if author was referring to changes during 24 weeks with ma or 12 weeks without.</span></div>
</td></tr>
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<span style="font-family: "arial"; font-size: 12pt;"><br clear="all" style="page-break-before: always;" /><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></span><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span><br />
<div class="MsoNormal">
<br /></div>
<br />
<table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" id="table3" style="border-bottom: medium none; border-collapse: collapse; border-left: medium none; border-right: medium none; border-top: medium none; margin-left: -32pt;"><tbody>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">14</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">17 cats treated with MA were compared to 97 cats not treated with MA</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">2.5 – 5 mg daily - treatment length varied</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Tissue analysis </span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">14 benign growths</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">3 cancerous growths</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Scientific discussion beyond my grasp</span></div>
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<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">17</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Number of cats not given</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Study</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">“high doses” for 12 months</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">“The results of this study demonstrate that administration of megestrol acetate to cats can produce a state of moderate to severe glucose intolerance, which is usually reversible after cessation of treatment. </span></div>
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<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">18</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">14 cats total </span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">7 received MA</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">7 received prednisone</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">3 received nothing</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Study of “adrenal cortisol response to exogenous adrenocortic-otrophic hormone” </span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">at doses equal to those used for skin conditions</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">7 received 5 mg MA daily for 16 days</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">7 received prednisolone 2mg/kg daily for 16 days</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">3 cats received no medications and served as controls</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Suppression cortisol levels day 8 both ma and prednisolone treated cats</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Day 15 more marked change in MA recipients vs. prednisolone recipients</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Day 30 </span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Recovery of adrenal reserve present in 6 of 7 cats given prednisolone, but in only 3 of 7 receiving MA. Decrease in Eosinophils (white blood cells), excess sugar in urine and liver cell swelling from glycogen deposition were occasionally recorded in treated cats of both groups. </span></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<br /></div>
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<span style="font-family: "arial"; font-size: 12pt;"><br clear="all" style="page-break-before: always;" /><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></span><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span><br />
<div class="MsoNormal">
<br /></div>
<br />
<table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" id="table4" style="border-bottom: medium none; border-collapse: collapse; border-left: medium none; border-right: medium none; border-top: medium none; margin-left: -32pt;"><tbody>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">19</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">6 cats </span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Study</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">5 mg daily for 8 days</span></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">On separate occasion </span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">given prednisolone @2 mg/kg of body weight/day for 8 days – time</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">The drugs induced similar increases in fasting blood glucose concentrations and decreases in glucose excretion rates in the cats. Usually, each cat developed reduced tolerance of an IV glucose load; concomitant fasting hyperglycemia occurred in 3 cats after prednisolone therapy, and in 1 of these 3 cats after megestrol acetate</span></div>
</td></tr>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">22</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">13 cats </span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Insulin therapy in cats with diabetes</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage and length of treatment not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">3 developed diabetes after MA therapy. 2 got insulin and the diabetes reversed, one received no drug treatment and the diabetes reversed. </span></div>
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<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">23</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">21 cats </span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Skin problems</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">5 mg per cat per day for 7 days then 5 mg every 3 days for 21 days</span></div>
<div class="MsoNormal">
<br /></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Side effects encountered were increased appetite, personality changes and depression.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">In all cats, a good improvement of the lesions was noted as soon as treatment was started. In 25% of the patients, one treatment schedule was sufficient to control the skin disease for at least 18 months. In the remaining 75%, two treatment schedules and/or a maintenance dosage had to be established</span></div>
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<span style="font-family: "arial"; font-size: 12pt;"><br clear="all" style="page-break-before: always;" /><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></span><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span><br />
<div class="MsoNormal">
<br /></div>
<br />
<table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" id="table5" style="border-bottom: medium none; border-collapse: collapse; border-left: medium none; border-right: medium none; border-top: medium none; margin-left: -32pt;"><tbody>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">24</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">20 cats total </span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">16 received MA</span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">4 received no medication and served as controls</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Study of adrenocortical suppression in cats given MA</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">8 <span class="highlight">cats</span> at a dose of 2.5 mg every other day for 2 weeks</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">8 <span class="highlight">cats</span> at 5.0 mg every day for 2 weeks</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">4 cats rec’d no No treatment for 2 weeks and served as controls </span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"><span class="highlight">Cats</span> were restrained with acepromazine maleate and ketamine hydrochloride during blood sample collection and large-dose glucose infusion</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Each week 1 control cat and 2 cats from each group was euthanized and analyzed.</span></div>
<div class="MsoNormal">
<br /></div>
<span style="font-family: "arial";"><span style="font-family: "arial" , "helvetica" , sans-serif;">Significant impairment of adrenocortical function and alteration of adrenocortical morphology occurred with both treated groups. The most severe adrenocortical alterations occurred in the <span class="highlight">cats</span> 1 week after <span class="highlight">megestrol acetate</span> was no longer given (i.e., experiment week 3). <span class="highlight">Megestrol acetate</span>-induced adrenocortical suppression contributed to the death of 1 cat. It was concluded that if stress occurs to <span class="highlight">cats</span> on treatment or soon after treatment with <span class="highlight">megestrol acetate</span>, glucocorticoids should be supplemented. The effects of <span class="highlight">megestrol acetate</span> on glucose tolerance were overshadowed by the unforeseen intolerance caused by chemical restraint with acepromazine maleate and ketamine hydrochloride.</span></span><br />
<div class="MsoNormal">
<br /></div>
</td></tr>
</tbody></table>
<span style="font-family: "arial"; font-size: 12pt;"><br clear="all" style="page-break-before: always;" /><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></span><span style="font-family: "arial" , "helvetica" , sans-serif;"> </span><br />
<div class="MsoNormal">
<br /></div>
<br />
<table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" id="table6" style="border-bottom: medium none; border-collapse: collapse; border-left: medium none; border-right: medium none; border-top: medium none; margin-left: -32pt;"><tbody>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">27</span></div>
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<br /></div>
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<br /></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">1 cat</span></div>
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<br /></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">1 cat</span></div>
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<br /></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<br /></div>
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<br /></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">1 cat</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">18 year old neutered male</span></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">10 year old neutered male</span></div>
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<br /></div>
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<br /></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">3 year old</span></div>
<div class="MsoNormal" style="margin-left: -130.95pt;">
<span style="font-family: "arial" , "helvetica" , sans-serif;">neutered male</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Skin problems</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Skin problems</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Skin problems</span></div>
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<br /></div>
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<br /></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">5 mg every other day for 2 weeks</span></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Initially treated with 30 mg methlylprednisolone acetate4 intramuscularly. Two months later he was treated with <span style="color: blue;">5 mg megestrol acetate on alternate days - period of time not given </span></span></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">See “Side Effects” column</span></div>
<div class="MsoNormal">
<span style="color: blue;"><span style="font-family: "arial" , "helvetica" , sans-serif;">MA in blue</span></span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Other med’s in black</span></div>
<div class="MsoNormal">
<span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Symptoms in green</span></span></div>
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<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">Symptoms post MA</span></span></b></div>
<div class="MsoNormal">
<b><span style="color: #339966;"><span style="font-family: "arial" , "helvetica" , sans-serif;">in bold green </span></span></b></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: windowtext 1pt solid; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Previous history of diabetes that had reversed one year prior –previous corticosteroid treatment. After MA developed high blood sugar –was treated but died</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Excessive thirst, excessive dilute urine, excessive appetite and weight loss appeared within ten days. The cat was stabilized on insulin and megestrol acetate therapy was continued. Within a month, signs of high blood sugar appeared and therapy was stopped. The cat has remained normal since. </span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Intralesional injection of 20 mg methlylprednisolone acetate. <span style="color: #339966;">When the lesion didn’t heal</span>, surgical excision was performed. When <span style="color: #339966;">the granuloma recurred</span>, the cat received 2.5 mg prednisone5 daily and 100 mg chloramphenicol ' daily. One week later, <span style="color: #339966;">surgical</span></span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"><span style="color: #339966;">excision was again attempted and when this failed</span>, the cat was treated with <span style="color: blue;">5 mg MA on alternate days</span>. The lesion was also injected with 0.4 cc triamcinolone. The treatment was repeated <span style="color: blue;">two weeks later and the MA continued. </span>The cat was admitted again after two weeks for <span style="color: #339966;">excessive urination, excessive thirst and an elevated temperature of 40.30C</span>. The cat was stabilized with insulin and megestrol acetate therapy was discontinued. The insulin dose was gradually reduced over ten days and the cat is doing well. </span></div>
</td></tr>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">31</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">244 cats</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Sex and age not given</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Birth control</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">2.5 mg weekly for 30 weeks</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">No pregnancies – 21 showed heat signs – </span></div>
<span style="font-family: "arial";"><span style="font-family: "arial" , "helvetica" , sans-serif;">Side effects were increased appetite, weight increase and changes of temperament were the most pronounced. One cat developed pyometra after three years of treatment with the preparation.</span></span><br />
<span style="font-family: "arial";"><span style="font-family: "arial" , "helvetica" , sans-serif;">Oslo 1974</span></span><br />
<div style="background: #ffff99;">
<span style="font-family: "arial";"><span style="font-family: "arial" , "helvetica" , sans-serif;">Pyometra 1 in 244 = .4%</span></span></div>
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</td></tr>
<tr><td style="border-bottom: windowtext 1pt solid; border-left: windowtext 1pt solid; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 52.15pt;" valign="top" width="70"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">33</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 74.8pt;" valign="top" width="100"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">9 cats</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 65.45pt;" valign="top" width="87"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">3 intact 6-8 month pregnant females </span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">1 intact “aged” pregnant female</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">2 neutered males age not given</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">3 spayed females age not given</span></div>
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</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 93.5pt;" valign="top" width="125"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Birth control?</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Birth Control?</span></div>
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<br /></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Skin problems</span></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;"> </span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Skin problems</span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 156.45pt;" valign="top" width="209"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage and treatment length not given</span></div>
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<br /></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"> Dosage and treatment length not given</span></div>
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<br /></div>
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<br /></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage not given – treatment for 14 months to 5 years</span></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Dosage not given – treatment for 14 months to 5 years </span></div>
</td><td style="border-bottom: windowtext 1pt solid; border-left: medium none; border-right: windowtext 1pt solid; border-top: medium none; padding-bottom: 0in; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0in; width: 305.65pt;" valign="top" width="408"><div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Enlarged mammary glands – cat was spayed – returned to normal</span></div>
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<br /></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "arial" , "helvetica" , sans-serif;"> Enlarged mammary glands – cat was spayed – returned to normal</span></div>
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<br /></div>
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<br /></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Enlarged mammary glands – lesions excised – no recurrence during follow up period</span></div>
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Enlarged mammary glands – lesions excised – no recurrence during follow up period</span></div>
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</tbody></table>
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<div class="MsoNormal" style="margin-left: -46.75pt; text-indent: 46.75pt;">
<br /></div>
tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-85246192214963424172018-07-19T19:24:00.000-07:002018-07-20T13:53:31.857-07:00French MA Report translated using Google <div class="MsoNormal">
<b><span style="color: blue; font-size: 11.0pt;">TRANSLATED
FROM FRENCH USING GOOGLE TRANSLATE.</span></b></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">NATIONAL
COMMISSION OF VETERINARY DRUG EXPERT REPORT OF DRUG</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">on the CNPV
NOTICE - 02 9/12/2003</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Assessment of
adverse effects in the short and medium term oral progestins</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">based
megestrol acetate used for the prevention and interruption of heat in dogs and
cats of 9 December 2003</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">I, Gerard
Keck, president of the National Committee of veterinary pharmacovigilance</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">certify that
the expert report on adverse short and medium term effects of progestin-only</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">oral-based
megestrol acetate used for the prevention and disruption of heat in dogs and
cats. and conclusions presented in this report were adopted at the meeting of
the National Committee of veterinary pharmacovigilance of 9 December 2003.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Ferns,
2February 2004 GERARDKECK</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">_____________</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">INTRODUCTION</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">The National
Commission of Veterinary Pharmacovigilance has received May 30, 2002 by AFSSA -ANMV
(National Agency for Veterinary Medicinal Products) a request for an opinion on
undesirable effects in short and long-term oral progestins based megestrol
acetate used for the prevention and'. Interruption of heat in carnivores This
request results from two complaints from cat owners and stating, after taking a
veterinarian based drug megestrol acetate in appearance:</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> a
complicated pyometra of Acute renal failure after a single dose</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> mammary
tumors after several doses.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">In both
cases, uterine infections and breast led to the death of the animal. These
complaints emphasize the lack of information on the risks involved taking this
drug both</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">on the
package leaflet and when buying from pharmacies (this product is distributed</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">exclusively
in pharmacies).</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">These
veterinary drugs basis of megestrol acetate for the carnivores may be</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">exempted from
the regulation of poisonous substances if: </span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> these
veterinary drugs are administered orally or subcutaneously presented</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">tablets,</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> the limit
dose of active ingredient per tablet (unit making) is 20 mg</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> the
maximum amount of substance is given to the public of 200 mg (Order of 3
December 1986 amending for pets Order of 20 July 1949 on the exemption from the</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">regulation of
substances poisonous for veterinary medicine.)</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">In the double
objective of assessing the risks associated with the administration of the
veterinary drugs and reconsider this particular provision to exempt, AFSSA calls
on the Commission to specify the frequency and risk characteristics of the use
of all medicinal products veterinary containing megestrol acetate used for the
prevention and disruption of heat.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">4</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Megestrol
acetate is a synthetic progestin steroid progesterone derivative used</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">only by oral.
Its contraceptive effect is due to inhibition at the hypothalamic level of</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">pulsatile
GnRH secretion and thus secondarily cyclical secretion of pituitary FSH and</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">LH, thus
inducing a prolonged anoestrus. This molecule, like other synthetic
progestogens, also a non-selective affinity for progesterone receptors present
in the target organs of sex steroid hormones such as the uterus and breasts: the
uterus, megestrol acetate can induce hyperplasia glandulokystique variable
intensity and udder it causes an increase in the local production of growth
factors GH (growth hormone) and IGF 1-5 (insulin like growth factors) leading to
breast enlargement. It also has a central action on the limbic system and
antagonizes the effect of insulin (11). Antiandrogen Its share (11) justifies
its use for hypersexualisme. This study focused on 11 veterinary drugs for which
reports periodic safety were provided by the licensees of marketing. A total of
98 declarations submitted during the period 1994-2002 were studied.70 of these
statements relate to reactions occurring in .cats after administration and 28
other ones occurring in dogs during this period a total of 131,937,960 tablets
were sold-.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">This report
is structured as follows:</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> -Study of
side effects reported in cats</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">- Study of
reported adverse reactions in dogs</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">-
Bibliographic data</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">- Conclusion
and proposals</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">5</span></div>
<div class="MsoNormal">
<b><span style="font-size: 16pt;">1. STUDY
OF SIDE EFFECTS REPORTED IN THE CAT</span></b></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">1.1. DRUGS
BASED MEGESTROL ACETATE FOR THE PREVENTION AND INTERRUPTION OF HEAT</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Eight
veterinary drugs, whose characteristics are reported in Table 1 are available</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">in veterinary
medicine for the treatment and the interruption of heat in the cat :</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 1</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Veterinary
Drugs based megestrol acetate for the treatment and the interruption</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">of heat in
the cat</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
species Brand name dosage/pill pills per pkg. ?</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shapetype id="_x0000_t75"
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height:183.75pt'>
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o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="245" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image002.gif" v:shapes="_x0000_s1025" width="535" /><!--[endif]--></span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">In cats, the
generally recommended for six of the seven drug regimens</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Veterinary
are 5 mg / animal every 15 days to prevent heat. For Pilucalm and</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Pill'kan5,
the regimen is different (Table 2).</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">For the
prevention of heat (Table 2), regimens differ from one medicine.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">to another
veterinary Some of these veterinary drugs Mégécat, Mégédine can also be</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">used to treat
miliary dermatitis. </span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 2</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">progestin
regimens based megestrol acetate available for feline species</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Preventing
heat, heat Interruption</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1026"
type="#_x0000_t75" style='width:6in;height:226.5pt'>
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o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="302" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image004.gif" v:shapes="_x0000_s1026" width="576" /><!--[endif]--></span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Felipil
- Prev - 5 mg daily for 15 days - Int – 5 mg per
day for 3-5 days</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Megecat
Prev 5 mg daily for 15 days Int -not given</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Megepil
Prev 5 mg daily for 15 days Int - not given</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
Minipil Prev 5 mg daily for 15 days Int –
not given</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Megedine
Prev not given Int 10 mg per day
for 8 days </span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Pill'ka 5
. Prev- 2.5 mg 3 times per week for 2 months Int-5 mg for 8 days</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Pilucalm
Prev - 5 mg/10 kg for 32 days Int-20 mg/10 kg / 8 days</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Side effects
(Table 3) differ veterinary drugs:</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 3</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1027"
type="#_x0000_t75" style='width:6in;height:474pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image005.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="632" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image006.gif" v:shapes="_x0000_s1027" width="576" /><!--[endif]--></span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 3
translation :</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Title :
Contraindications and side / adverse</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Column
Headings : Name Submitted side effects Adverse Contraindication</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Felipil
</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E -
treatment sometimes results in males and females decreased vagrancy and</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">sometimes
increased appetite. </span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C -
metritis, pregnancy, diabetes, association with Estrogen </span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Megecat
</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E -
Increased appetite, weight gain. </span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C -
Diabetes, pregnancy, infection, Reproductive tract pre-pubescent females.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Mégépil</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E -
tolerance pharmaceutical form Mégépil cat has been evaluated in a clinical
controlled study.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C - should
not be administered before the first estrus Do not administer to female pre
-pubescent</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Minipil</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E – No
(none ?)</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C - Do not
administer to diabetic females with uterine infection, immature,</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">pregnant or
under estrogenic impregnation treatment.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Megedine</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E -
Increased appetite, weight gain, hyperplasia glandulocystic.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C -
disorders of the reproductive tract and mammary tumors,diabetes,
pregnancy,females. prepubescent Do not use during pregnancy.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Use possible
in case of lactation.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Opochaleurs</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E -
treatment can cause by prolonged repetitive administration and a</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">change of
temperament, a development, breast increased</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C -
gestation appetite,Condition of the unit reproductive,female puberty, diabetes,
breast tumors</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Pilucalm</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E -
megestrol acetate causes in some cases an increase in appetite and weight gain.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">These effects
are transient and cease after shortly stopping treatment.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C - acetate
megestrol causes no pyometra or ovarian cyst. A bitch treated Pilucalm</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">20 may be
normally fertilized his next heat with a normal pregnancy and</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">a normal
range. Like all synthetic progestins, is against Pilucalm indicated in cases of</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
diabetes,uterine infection and pregnancy. Pilucalm 20 does will not be used if
the female</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">is under
estrogenic impregnation therapeutic</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Pill'kan 5</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">S/E
-treatment may lead to prolonged repetitive administration and a change of
temperament, a development, breast increased appetite</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A/C Do not
use if :</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> genital
disease,</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">�diabetes
</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">breast
tumors</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> in
pregnant females and females prepubescent</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">7</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">1.2. SUMMARY
OF SIDE EFFECTS - CHAT</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
1.2.1.reported cases</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Some MAHs
laboratories, as shown in Table 4, the information collected before the</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">formal
establishment of pharmacovigilance.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1028"
type="#_x0000_t75" style='width:6in;height:150pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image007.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="200" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image008.gif" v:shapes="_x0000_s1028" width="576" /><!--[endif]--></span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Period
covered by the periodic safety report</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Date on the
market</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Distributed
by ?</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Period</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Only cases
reported since 1994 were considered. All adverse events following the use of
these drugs to treat miliary dermatitis were excluded from this study. In
response to the report, the names of eight veterinary drugs will anonymysé:
Specialty-A,Specialty-B, Specialty-C,Specialty-D, Specialty-E,-Specialty-F,
Specialty-G,Specialty-H</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">(abbreviation
Sp on the graphs).</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Ultimately,
70 cases reported in cats (Figure 1), including 16 fatal cases were evaluated.
Such a statement can report adverse events to one or more animals, these to
total</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">statements
relate83 treated animals including 20 dead. For two veterinary drugs,</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Specialty
Specialty-C and Specialty -D, no cases have been reported.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Figure 1:
Annual distribution of cases by specialty</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1029"
type="#_x0000_t75" style='width:6in;height:201pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image009.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="268" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image010.gif" v:shapes="_x0000_s1029" width="576" /><!--[endif]--></span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Figure 1
Cases by brand name</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Left column -
Number of cases /Year</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Bottom Row –
year</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Color coded
by specialty (mfr name)</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1030"
type="#_x0000_t75" style='width:431.25pt;height:210pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image011.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="280" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image012.gif" v:shapes="_x0000_s1030" width="575" /><!--[endif]--></span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Figure 2 –
Number of cases by brand name</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">58 of these
cases involve adverse reactions in females, 9 cases involved</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">male animals
and 3, no information is given on the sex of animals.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">The number of
reported cases was the most important for the specialty-B (48 cases). For other
drugs,veterinary the number of cases is lower: Specialty E-8, A-7,G-4,H- 2</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">F-1, C-0,D-0</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">I</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1031"
type="#_x0000_t75" style='width:6in;height:192pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image013.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="256" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image014.gif" v:shapes="_x0000_s1031" width="576" /><!--[endif]--></span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Figure 3
Distribution of imputation for the reported adverse reactions following the
administration of megestrol acetate in cats</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">In 70% of
cases, the race of cats is unknown or unspecified. European breeds, Siamese,</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Persian and
chartreuse are respectively 22, 4, 3 and 1 of the owners identified.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">The case
description is often incomplete, and 55% of them (Figure 3), it was not possible
to establish a link (imputation O) between the observed response and veterinary
medicine based 'acetate megestrol-.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">For 4 cases
Specialty E 3 cases and 1 Specialty A case - there is no link between the
adverse effect and the drug symptomatology. for the rest of the synthesis, it
was considered that these four cases "N" should be removed to determine the
profile and calculation of incidence. The remainder of the study focused on 66
cases charged A, B and O.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">1.2.3.
Symptomatology</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">154 clinical
signs were mentioned to describe 66 cases reported. It should be noted that
several signs different clinical can be mentioned to describe each case. Figure
4 below and Table 5 show the relative proportion of these clinical signs.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1032"
type="#_x0000_t75" style='width:6in;height:298.5pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image015.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="398" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image016.gif" v:shapes="_x0000_s1032" width="576" /><!--[endif]--></span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Figure 4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Major
clinical signs mentioned to describe the side effects in cats</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">(% sign / 154
clinical signs used to describe cases)</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">24% Major
Functions</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">10% other ?</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">10% Nervous
and behavioral</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">4% weight</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">5% Mucosa and
skin</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">6% Sugar
metabolism</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">3% fetal
disorders</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">8% mammary
tumor</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">5% other
disorders of the mammary gland</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">3% genital
tract neoplasm</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">22% other
genital disorders</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Major
Functions included all the effects on liver damage, kidney and gastrointestinal</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
Miscellaneous: General disorders + ineffective in 24% of reported cases of
pyometra are diagnosed and represent approximately 42% (16/38) described in the
lesions of the genital tract. Moreover, in about 20% of cases, tumors of the
mammary gland are also notified. A single case of cancer of the mammary chain
was reported by the owner without the diagnosis has been confirmed by a
veterinarian. Pyometra and mammary tumors were associated only in two cases.</span></div>
<div class="MsoNormal">
<br /></div>
<span style="font-family: "arial"; font-size: 11pt;">
<br clear="all" style="page-break-before: always;" />
</span><br />
<div class="MsoNormal">
<span style="font-size: 11pt;">
</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1033"
type="#_x0000_t75" style='width:431.25pt;height:519.75pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image017.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="693" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image018.gif" v:shapes="_x0000_s1033" width="575" /><!--[endif]--></span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">10</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 5</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Clinical
signs mentioned in the case to describe the adverse reactions (case A-BO)</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">in cats</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Number of
times the sign is mentioned ************** clinical signs * Number of
times</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">reproductive
tract tumor 4</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">tumor of ovaries or uterus4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Other
diseases of the genital tract 34</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
Pyometra16</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
metritis, vaginal discharge uterine hypertrophy 18</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">tumor of
mammary gland 13</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">tumor of mammary gland 12</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">breast carcinoma 1</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Other
disorders of the gland mammary 8</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
hyperplasia mammary- 4</span></div>
<div class="MsoNormal" style="margin-left: .5in;">
<span style="font-size: 11pt;">Swelling of the mammary gland
abscess of the mammary gland mammary gland hypertrophy - 4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Reproductive
-4</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Fetal Death mummification 4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Efficiency -5</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Lack of efficacy- 5</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Hyperglycemia
carbohydrate10</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Effect on metabolism 8 </span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Hypoglycemia 2</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Effect on
skin and mucousa -7</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">congestion cyanosis Alopecia
Erythema Skin Dehydration 7</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Effect on
weight- 6</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;"> weight gain, weight loss 6</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Signs nervous
and behavioral -16</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Hyperesthesia aggressiveness
depression, apathy, lethargy,</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">ataxia, paresis 16</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">hyperthermia, hypothermia,
prolapse of the third eyelid -7</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Changing hematology: anemia,
lymphocytosis, thrombocytopenia- 4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">General
disorders - 36</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Kidney and bladder: renal failure,
renal tumor,hematuria, urinary incontinence 5</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Liver cirrhosis, jaundice, liver
tumor 5</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Lung dyspnea 3</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Abdomen Abdominal Pain
peritonitis, pancreatitis,7</span></div>
<div class="MsoNormal" style="text-indent: .5in;">
<span style="font-size: 11pt;">Digestive tract: anorexia,
polydipsia salivation, vomiting,constipation, diarrhea 16</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Total 154 154</span></div>
<ul style="margin-bottom: 0in; margin-top: 0in;" type="disc">
<li class="MsoNormal"><span style="font-size: 11.0pt;">=
Number of fatal cases not considered in this specification – 11</span></li>
<li class="MsoNormal"><span style="font-size: 11.0pt;"> </span></li>
</ul>
<div class="MsoNormal">
<span style="font-size: 11pt;">In 54% of
reported cases, no information on the time to onset of adverse events from</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">the beginning
of treatment is available. However, when we have the information, very large
variations are observed in the timing of onset of pyometra or mammary tumors 2
days after the start of treatment in 10 years for the occurrence of pyometra and
15 days to 6 years for the appearance of a breast tumor.</span></div>
<div class="MsoNormal">
<br /></div>
<span style="font-family: "arial"; font-size: 11pt;">
<br clear="all" style="page-break-before: always;" />
</span><br />
<div class="MsoNormal">
<span style="font-size: 11pt;">
1.2.4.incidence,</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Arbitrarily
the incidence was calculated by taking as a basis the dosage regimen of one</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">tablet every
15 days to prevent heat. Thus, it has been estimated that the average cat</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">was likely to
receive 24 tablets per year. Also were considered:</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> average
sales volume specialties over a year and specialty treated..</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"> the
average number of cases per year for a specialty year</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">the number
of animals likely to have been during one year</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1034"
type="#_x0000_t75" style='width:431.25pt;height:230.25pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image019.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="307" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image020.gif" v:shapes="_x0000_s1034" width="575" /><!--[endif]--></span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 6</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 6
summarizes all the sales and calculate the incidence veterinary medicinal-.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Specialities
</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Calculation
of incidence veterinary medicine (case A - B-O) 66 cases cat</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Brand</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Number pills
sold</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Number cases
reported per year</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Incidence per
100K pills</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Number of
animals treated </span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Incidence per
100K animals </span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<span style="font-family: "arial"; font-size: 11pt;">
<br clear="all" style="page-break-before: always;" />
</span><br />
<div class="MsoNormal">
<span style="font-size: 11pt;">
Figures 5 and 6 provide a graphical illustration of the impact they are
evaluated according to the number of animals treated or the number of tablets
sold</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1035"
type="#_x0000_t75" style='width:431.25pt;height:258pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image021.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="344" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image022.gif" v:shapes="_x0000_s1035" width="575" /><!--[endif]--></span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Figure 5:
Number of notifications reported sales figures (annual basis)</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Figure 6:
Number of notifications reported to the numbers of animals that have been
treated <!--[if gte vml 1]><v:shape id="_x0000_s1036"
type="#_x0000_t75" style='width:6in;height:299.25pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image023.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="399" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image024.gif" v:shapes="_x0000_s1036" width="576" /><!--[endif]--></span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Number of
animals treated (24 tablets per year)</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Annual
Incidence per 100K animals treated</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">13</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">For
veterinary drugs also used for the treatment of miliary dermatitis, it was not</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">possible to
estimate the proportion prescribed medications only under contraception. In</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">addition, for
mixed veterinary drugs (for cats and dogs), it was not possible</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">to estimate
the proportion of cats actually treated. It is noted that according to
veterinary drugs, the incidence varies between 0 reactions and 4.1379 per
100,000 treated animals and between 0 and 0.1724 reactions 100,000 tablets sold.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">In cats, the
overall average incidence of reactions to 0.0645 100,000 tablets sold and</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">1.55
reactions per 100 000 animals receiving treatment 24 tablets per year, however,
given the uncertainty calculations, these figures should be taken with caution.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">February</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<b><span style="color: blue; font-family: "arial"; font-size: 11.0pt;">
<br clear="all" style="page-break-before: always;" />
</span></b><br />
<div class="MsoNormal" style="background: #99CCFF;">
<b>
<span style="color: blue; font-size: 11.0pt;">14.STUDY OF SIDE EFFECTS REPORTED
IN DOGS (did not copy charts)</span></b></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2.1. DRUGS BASED MEGESTROL ACETATE
FOR THE</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">PREVENTION AND INTERRUPTION OF
HEAT</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">As for the cat, notices differ.
Tables 7 and 8 show the veterinary medicinal containing</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">productsmegestrol acetate
available for the canine species and treatment</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">recommendedregimens.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Table 7</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Veterinary Drugsbased megestrol
acetate available for the canine species</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Drugs</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Veterinary</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">content /</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">compressed package</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pilucalm 20 20 mg 16 tablets</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">10 mg 16 tablets Pilucalm</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pill'kan May 5 mg sugar8</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pill'kan20 20 8 sugarsmg</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Canipil10 mg 20tablets</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mg 10Minipil 5, 20 and 30</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">tablets</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mgMegedine 10 16 and 32 tablets</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Opochaleurs 10 mg 16 tablets or 8</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Table 8</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">regimens of veterinary medicinal
products containing megestrol acetate</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">in the canine species</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Drugs</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">VeterinaryPrevention heat
Interruption heat</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Minipil 5 mg/10 kg / d 32 d before
heat -</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pilucalm 20 5 mg/10 kg / day 32
days 20 mg/10 kg / day 8 days</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pilucalm 5 mg/10 kg / day 32 days
20 mg/10 kg / day 8 days (1)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pill'kan May 5 mg/10 kg / j 32
days 20mg/10 kg / day 3 days then ½ dose</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">for 7 days (2)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pill'kan May 20 mg/10 kg / day 32
days 20mg/10 kg / day 3 days then ½ dose</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">for 7 days</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Canipil 5 mg / 10 kg / day 1 month
20 mg/10 kg / day 8 days</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Opochaleurs 5 mg/10 kg / day 32
days</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Megedine - 20 mg/10 kg / day 8
days</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">(1) other regimens for Pilucalm:</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">- lactation pseudopregnancy: 20
mg/10 kg / day for 8 days and 20 mg/10 kg, 2 times per week for 2</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">weeks</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">- hypersexuality 20 mg/10 kg / day
for 7 days. If improved, continue at a dose of 10 mg/10 kg / day</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">for 14 days. If administered 40
mg/10 kg / day for 7 days and 10 mg/10 kg / day for 14 days. If</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">no improvement occurs, discontinue
treatment-.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">(2) other regimens for Pill'kan:</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Hypersexuality in males: 20 mg/10
kg / day for 8 days, and 10 mg/10 kg / day for 8 days.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Table 9 shows the cons-indications
and side / adverse effects brought on records</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">and / or on the label of
veterinary medicinal products for dogs.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">15</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Table 9</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Contraindications and side /
adverse</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">side effects filed Name / adverse
Contraindications and precautions</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Minipil No</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Do not administer to diabetic
females</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">with uterine infection, immature,
pregnant</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">or under estrogenic impregnation</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treatment.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">PILUCALM</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">megestrol acetate causes some</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">incases, increased appetite and</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">decisionweight. These effects are
transient and cease</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">shortly after discontinuation</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">of megestrol acetate does not
cause</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">pyometra or ovarian cyst. A bitch</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treated Pilucalm 20 may
befertilized</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">normallyhis next heat with</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">a normal pregnancy and a normal
range.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Like all synthetic progestogens,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pilucalm is against-indicated in
cases of</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">diabetes,uterine infection and
pregnancy.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pilucalm 20 will not be used if
the female is</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">under estrogenic
impregnationtherapeutic</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">PILL'KAN</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treatment may exceptionally cause</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">by prolonged and repeated
administration, a</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">change in temperament</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mammary development,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">increasedappetite</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">-.Affection of Reproductive</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">- Diabetes</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">- Female in gestation</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">- prepubescent females</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">-mammary tumors</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">CANIPIL Diabetes, pregnancy,
metritis</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Do not combine with estrogen
hormones</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">OPOCHALEURS</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Exceptionally, in case
ofadministration:</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">prolonged and repetitive</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">behavior modification,development,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">breast increased of appetite</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Diabetes, pregnancy,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">prepubescent females,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">reproductive condition of</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mammary tumors</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">MEGEDINE Increased appetite,
weight gain,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">hyperplasia glandulocystic.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">disorders of the reproductive
tract andtumors,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mammary diabetes, pregnancy,
female</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">immature. Do not use during
pregnancy-...</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Can be used in case of lactation</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">16</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2.2 SUMMARY OF SIDE EFFECTS - DOG</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2.2.1. Number of reported cases</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Some firms (Table 10) collected
the information before the formal establishment of</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">pharmacovigilance.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Table 10</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Period covered by the periodic
safety report</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Date of the</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">firm marketPeriod</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Minipil11/02/1983 CEVA SANTE
ANIMAL 1983 - 12/2002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">20 Pilucalm</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pilucalm 24/02/1988 / 28/11/1983
NOVARTIS 1998-2002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Canipil VETO CENTRE 22/07/1987
01/01/1996 - 31/12/2002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Pill'Kan May 18 / 10/1985 CLEMENT
- THEKAN 01/01/1999 - 31/12/2002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">21/05/1984 Pill'Kan 20 CLEMENT -
THEKAN 01/01/1999 - 31/12/2002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">11/02/1983 Opochaleurs CLEMENT -
01 THEKAN / 01/1999 - 31/12/2002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Megedine ARKOMEDIKA 02/07/1980
01/01/1998 - 31/12/2002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">For the remainder of this report
on behalf of the seven veterinary drugs will anonymysé specialties: Specialty I,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">J Specialty, Specialty-K-L
Specialty, Specialty-M, N-Specialty, Specialty-O (Sp Abbreviation on</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">graphs.)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">No adverse effects have been
reported in dogs for veterinary medicinal Specialty K,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">J Specialty, Specialty Specialty O
and M. For other veterinary drugs, a total of 28 cases have been</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">reported (Figure 7): 20 cases
Specialty I, 1 L Specialty cases, 7 cases Specialty N. Three of them were in</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">seriouscases resulting in death of
the animal being treated. 30 dogs were treated.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Figure 7</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Number of cases reported per year
in the dog</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">3</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">4</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">5</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">6</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">7</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Years</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Case</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">sp L</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">SpI</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">SpN</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">94 95 96 97 98 99 00 01 02</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">17</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2.2.2. Imputation</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">In this species, the description
of the cases is sometimes incomplete, which has established only in</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">29% of reported cases, probable or
possible relationship (imputation A or B) between the adverse event</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">and product administered ( Figure
8). However, it should be noted that in two cases reported for Specialty N</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">(7% of cases), it was clearly
established that the observed effect was not related to the drug administered.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Figure 8</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Distribution of imputation for
reported adverse events following administration</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">of megestrol acetate in dogs</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">4%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">25% 57%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">7%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">7%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">A</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">B</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">O</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">N</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Unassessable</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2.2.3.symptoms</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">The two casescharged "N" have been
removed to make the symptomatic profile, the study focused on the26</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">remainingcases (Figure 9). 57
clinical signs were noted (several clinical signs per case) to</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">describe the symptoms of these 26
cases as shown in Table 11.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Figure 9</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Main clinical signs mentioned to
describe the side effects in dogs</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">(% sign / number of clinical signs
used for the description of cases)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">14%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">12%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">19%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">37%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2% 16%</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">of the mammary gland disorders</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Disorders ofgenital</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">nervous signs and behavioral</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">efficiencyMissing:</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Hematology and Biochemistry</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Major Functions</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Major Functions includes all
effects for cardiac lesions, lung, liver, kidney and gastrointestinal</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">18</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">As shown in Table 11, only 4 cases
of pyometra were diagnosed following the use product</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">oftheI and one case of breast
hyperplasia. These pyometra occurred within 11 to 30</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">days after a few days of treatment
(5-8 when information is available). In addition, several</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">reports (27% of cases) relate to
complaints about the lack of efficacy (unwanted pregnancy,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">pseudopregnancy, persistent
unwanted heat or heat) of these veterinary drugs.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Table 11</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Clinical signs mentioned in the
case described adverse reactions (26 cases</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">AB-O)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Number of</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">times the</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">sign is</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mentioned</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">clinical signs * Number of</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">times</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Lack of efficacy Gestation
unwanted, pseudopregnancy April</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">7Persistence of heat, heat
unintended 3</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">4 Pyometra</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">disorders unit genital metritis 8
3</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1 ovarian cyst</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">disorders of thegland</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mammaryhyperplasia breast 1 1</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">nervous andsigns,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">9behavioral</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Aggression hyperarousal</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">weakness, apathy</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">sleepiness, tremors</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">agitation, depression</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Tournis</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">9</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Effect onparameters</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">haematological and</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">biochemical11</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">bleeding</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">réticulocytose</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">disorder bleeding</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Anemia</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">leukocytosis,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">elevated alanine transferase</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">High Cholesterol</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">11</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Abdomen: distension 1</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Liver: Jaundice 1</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Heart: heart failure, tachycardia
2</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Lungs: dyspnea, tachypnea 3</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Kidney-Bladder: polyuria,
hematuria, hemoglobinuria 5</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Major Functions 21</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">digestive tract: anorexia,
polyphagia, polydipsia,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">salivation 9</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">* = number of fatal cases (3) not
taken into account in this description</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">19</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">2.2.4. Incidence</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Although several regimens are
available and although the levels of active ingredient</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">different from a veterinarian to
another drug, it was estimated that for treatment, the number of</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">tablets can vary between 8 and 32
depending on the veterinary drug . Forveterinary drugs</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mixed(for cats and dogs), it was
not possible to estimate the proportion of dogs actually</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treatedABO.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Table 12</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Calculation of the impact (annual
average) Veterinary medicine</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">(26 cases - DOG)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Specialty nonbre of</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">tablets</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">sold per year</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">number</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Averageof</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">cases / year</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Incidence /</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">100000comprimés</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">sold</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Treatment</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">(*)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Number</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">animals</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treated</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Incidence /</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">100,000 Ax</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp I 2 153 707 2.2222 0.1032 16
134 607 1.6509</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp J 49 514 0.0000 0.0000 32 49
514 0.0000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp K 145 003 0.0000 0.0000 32 145
003 0.0000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp L 676 243 0.2000 0.0296 16 42
265 0.4732</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp M 199 580 0.0000 0.0000 16 12
474 0.0000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp N 613 771 0.6250 0.1018 16 38
361 1.6293</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">sp.Ø 114 824 0.0000 0.0000 8 14
353 0.0000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Total 3952641 3.0472 0.0335-436
5760.5362</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">*= average number of tablets per
treatment</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Figures 10 and 11 provide a
graphic illustration of the impact they are evaluated according</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">tothe number of animals treated or
the number of tablets sold.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Figure 10: Number of notifications
reported sales figures ( annual basis) in DOG</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1 000000 000000 000000 000000 000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0002</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">3</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">4</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">5</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.0000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.0200</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.0400</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.0600</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.0800</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.1000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.1200</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">nonbre tablets sold 2153 49 514
145 003 676 243 199 580 613 771 114 824 3 952</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Incidence/100 000cp sold 0.1032
0.0000 0.0000 0.0296 0.0000 0.1018 0.0000 0.0335</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp I Sp Sp J K L Sp Sp Sp M N
sp.ØTotal</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">20</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Figure 11</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">number of notifications (annual
average) compared to the number of animals which have been</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treated (as recommended by 8, 16
or 32 tablets, according to veterinarian medicine)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">50 000000000000000000000000000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">100</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">000150</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">200</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">250</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">300</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">350</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">400</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">450</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">500</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.0000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.2000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.4000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.6000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">0.8000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1.0000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1.2000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1.4000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1.6000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">1.8000</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">No. of animals treated 134 607 49
514 145 003 42 265 12 474 38 361 14 353 436 576</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">000 Incidence/100 Ax 1.6509 0.0000
0.0000 0.4732 0.0000 1 6293 0.0000 0.5362</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Sp I Sp Sp J K L Sp Sp Sp M N
Total sp.Ø</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">The average incidence of adverse
effects in dogs was estimated at 0,536 reactions per 100 000animals.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treated However, given the
uncertainties regarding the actual number of tablets ingested during</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">treatmentand the inability to
establish the proportion of dogs actually treated during treatment with</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">mixedspecialties (cat-dog), this
figure must be treated with caution-..</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">21</span></div>
<div class="MsoNormal">
<b><span style="font-size: 11.0pt;">3 LITERATURE DATA</span></b></div>
<div class="MsoNormal">
<b><span style="font-size: 11.0pt;">3.1. LITERATURE DATA AT
THE CAT</span></b></div>
<div class="MsoNormal">
<b><span style="font-size: 11pt;">3.1. 1.
Data on uterine</span></b></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Endometrial
hypertrophy due to megestrol acetate is proven in 10 cats previously
ovariectomized receiving 10 to 30 mg of megestrol acetate per week (1). Lesions,
except for a cat that declares a pyometra (lot 30 mg), partially regress after
cessation of treatment. They exist also in non-ovariectomized cats
(14)métropathies:.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">A study has
helped to identify the percentage of 1 case per 244 cats treated</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">for 3.5 years
use.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">(22) extended
all progestin (15) can cause pyometra and cystic hyperplasia and acetate</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Megestrol is
a relatively benign progestin. Other publications describe the effects on the
uterus in the cat (26)</span></div>
<div class="MsoNormal">
<b><span style="font-size: 11pt;">3.1. 2.
Data on breast</span></b></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">In the feline
species, megestrol acetate causes effects in the breast (17, 21) and of the</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Hypertrophy
breast. Authors (9 & 13) have established the link between non-neoplastic
changes dominated by fibroadénomatose frequency and distribution of megestrol
acetate. A survey very recent MANAGED (study in breeding and canine sports
group) led by Dr Martine Lennoz (unpublished results) showed that out of 53
cases of fibroadénomatose, 13 had received a treatment progestagen and that
these blooms can breast occur following impregnation hormonal with normal doses
of megestrol acetate. The appearance of mammary hyperplasia imposes a judgment
of progestagen. Regression of lesions is often incomplete (18) suspected:.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">The link
between megestrol acetate and breast cancer has not been proven (3) but</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">First
publication (10) reports that 3 out of 17 cancers of breast changes are due to</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">megestrol
acetate and a second (25) reported that 17 cases of breast carcinoma, 4 were</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">developed on
cats receiving progesterone.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">3.1. 3. Other
data</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">are the many
publications on adverse effects described in the cat following</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
administration of megestrol acetate as hypoadrenocorticism (5, 6, 17), diabetes
mellitus (17, 20),behavioral changes (aggression or depression, polyphagia) and
weight gain (17, 21).It should be noted that publication (8) highlights the good
tolerance to megestrol acetate.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">22.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<b>
<span style="color: blue; font-size: 11.0pt;">3.2 LITERATURE DATA IN DOGS (no
edit)</span></b></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">3.2.1. Data on the uterus</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">In the bitch, progesterone also
induces hyperplasia of the endometrium, pyometra (15) and</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">cystic hyperplasia (14). As in the
cat, the number métropathies is low. Of 389 dogs</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">receiving megestrol acetate during
proestrus (4), 0.8% said no and pyometra in</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">119 dogs treated for anoestrus.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">3.2.2. Data on breast</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">In the bitch, repeated over a long
period of progestin administration can lead to</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">breast hyperplasia, lactation and
the onset of breast benign nodules (7, 19, 23, 24.)</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">In their study about 389 dogs
receiving megestrol acetate during proestrus, Burke and</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">Reynolds (4) found that 5.9% of
bitches have breast enlargement and 1% a</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">lactation.When megestrol acetate
is distributed during anoestrus (119 dogs) the percentage</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">decrease (5% and 0.8%).</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">3.3. INFORMATION RIGHTS</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">The megestrol acetate for breast
cancer-link process is not documented in the study except for MEGACE specialty
produced by BRISTOL-MYERS SQUIBB is dosed at 160 mg of acetate megestrol and
prescribed during the palliative treatment of carcinoma of the breast
(antiestrogenic effect) in humans.This specialty is cons-indicated in pregnant
women and / or have a history of thromboembolism.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">A paragraph on pre-clinical safety
of the summary of product characteristics indicates an</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">increase in the incidence of
benign and malignant mammary tumors in dogs subjected</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">to megestrol acetate
administration for seven years. Similar studies in rats and monkeys</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">have not demonstrated this
phenomenon. The clinical relevance of these observations has not been
established.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">MEGACE for the study in the dog
seems to attest to a sensitive species (dog) of the tissue breast to megestrol
acetate.</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
</div>
<div class="MsoNormal" style="background: #99CCFF;">
</div>
<div class="MsoNormal">
<b><span style="font-size: 11pt;">
CONCLUSIONS AND PROPOSALS</span></b></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">It should be
noted that this study took into account cases that occurred before the
establishment of veterinary pharmacovigilance operational since 2001 in France,
to better define the nature of the adverse events following administration of
these veterinary drugs. Since 2001, 33 cases cats and dogs have been reported
including 32 charged A, B or O. As 37,758,167 tablets were sold during this
period, the incidence of 0.088 per 100 000 tablets.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">This study
included 98 reports of adverse reactions in cats and dogs. They were</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">notified in
1994 and recorded December 31, 2002 for a total of 131,937,960 tablets</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">sold, which
represents about 0,074 cases per 100,000 tablets sold. The incidence of
reactions following administration of the oral progestin products based
megestrol acetate seems so low.</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">23</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">In addition,
for six of these cases, it was concluded that the adverse event could not be
linked to progestin ingested.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Notified side
effects for 92 cases charged A, B or O (Table 13) are many and varied as</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">in cats than
in dogs.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Table 13</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1037"
type="#_x0000_t75" style='width:431.25pt;height:213pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image025.emz"
o:title=""/>
</v:shape><![endif]--><!--[if !vml]--><img border="0" height="284" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image026.gif" v:shapes="_x0000_s1037" width="575" /><!--[endif]--></span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Main clinical
signs</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Case (A, B,
O)</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
66 cases cat 26 cases dogs</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
Fatal 13 3</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Tumor of
genital 4 0</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Pyometra
16 4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Other
disorders of the reproductive system (metritis, uterine hypertrophy ...) </span>
</div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
18 4</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">tumor of the
mammary gland 13 0</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Other
disorders of the breast 8 1</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Effect on
sugar metabolism 10 0</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">nervous and
behavioral signs 16 9 </span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<b><span style="font-size: 11.0pt;">in cats are described:</span></b></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">- in
approximately 54% of reported cases of diseases of the genital tract with
particularly</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">métropathies</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">-in 20% of
cases, non-cancerous tumors of the mammary gland, in this case,</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">literature
data indicate firstly a breast hyperplasia megestrol acetate link</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">is
established and secondly that the most common injury (fibroadénomatose) may
occur at the beginning of treatment with megestrol acetate. All breast changes
require a</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">judgment of
non-recommended treatment in the instructions</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">-in 24% of
cases, nerve and behavioral symptoms (aggression, depression, paresis ...)</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">with or
without weight gain</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">-a few
effects.the metabolism of sugar are also identified</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">in dogs are described:</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">- 30% of reported cases of
diseases of the genital tract with particularly métropathies</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">-in less than 4% of cases, breast
hyperplasia;</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">- in 35% of cases, nerve and
behavioral symptoms (aggression, weakness, drowsiness,</span></div>
<div class="MsoNormal" style="background: #99CCFF;">
<span style="font-size: 11pt;">restlessness ..)</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">The diversity
of the wording of against-indications and side effects have been clearly
identified. Most of the entries highlight the potential for use during
pregnancy, uterine and breast disease, diabetes and association with estrogen.
No one is suggesting the possibility of amétropathie after taking megestrol.
Some entries even emphasize the absence of risk of pyometra. The possibility of
breast modification is discussed. These changes are considered benign or
reversible. The nature of this potentially tumor breast disease is never
considered .Sometimes it is proposed to limit to 18 months duration of treatment
to avoid adverse effects. Moreover, it is important to note that this study of
identify the use of veterinary medicinal products based megestrol acetate in
dermatology to treat feline "miliary dermatitis"(2, 16) can cause different side
effects than observed when using as progestin the fact the duration of
treatment. An implementation of a study pharmacovigilance on megestrol acetate
in the indication "miliary dermatitis" may be initiated-.at the end, as side
effects may occur after the first dose of oral progestin, the terms "short and
long-term "contained in the wording of the referral will not be included in the
publication of the notice that will be on the side effects of progestin-only
oral based Megestrol acetate used for the prevention and interruption of .heat
in dogs and cats</span></div>
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">- Given the
relatively low incidence of adverse events reported less than</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">0.1per
100,000, the relevance of raising the exemption seems unfounded</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">-A campaign
information with retail distributors, pharmacists and veterinarians,</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">to raise
awareness of the need to inform future users of the risks of adverse reactions
may occur following the use of oral progestins to prevent or stop the heat in
domestic carnivores, should be launched</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
-harmonization of labels and conditions should be considered and references</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">further to
the adverse effects likely to be observed, must included be on the outside
label and, where appropriate, the instructions. The following wording on the
side effects can be proposed: "After single or repeated administration,
affections of the genital tract (hypertrophy, pyometra and uterine tumors) as
well as conditions of the udder (hypertrophy and mammary tumors) were noted,
cases of diabetes and behavioral changes (polyphagia, aggression or apathy) have
also been reported</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">"-In
addition, it would be:</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">25</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">⇒ remind
veterinarians and pharmacists their requirements for reporting</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">adverse
effects occurred after the administration of these veterinary drugs</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">in domestic
carnivores</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">⇒ further
study by the MANAGED (study in reproduction, breeding and Group)</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">dog sport
and set up a prospective investigation of progestin based megestrol acetate,
the protocol will be established by the pharmacovigilance centers.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">26</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">REFERENCES</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">1. BELLENGER
CR and JC CHEN effect of megestrol acetate on the endometrium of the
prepubertally ovariectomised kitten Research in Veterinary Science 1990 * 48:
112-118</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">2. BOURDEAU
P., BM PARAGON alternative to corticosteroids in dermatology Veterinary Rec.
Med.vet168: 1992 645-660</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">3. BRETON C.
FONTAINE JJ. Cases of cervical adenocarcinoma in a cat Vet Point 1990 22:
767-773</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">4. J. BURKE
A. REYNOLDS Megestrol acetate for estrus postponement in the bitch JAVMA 1975
167: 307-309</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">5. CHASTAIN
CB, CL et al GRAHAM Adrenocortical suppression in cats given megestro </span>
</div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
Am.J.vet.Resacetate.1981 42: 2029-2035</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">6. CHURCH DB
et al Effects of proligestone and megestrol on plasma adrenocorticotrophic
hormone, insulin and insulin-like growth factor-1 concentrations in cats Res Vet
Sci 1994 56: 175-8</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">7. DONNAY I.,
ravished J., J. VERSTEGEN Influence of hormonal background on the clinical
appearance of mammary tumors in dogs Ann. Med. Vet. 1994 138: 109-117</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">8. Feldman
EC, Nelson RW Feline Reproduction in Canine and Feline Endocrinology and
reproduction WB Saunders, Philadelphia 1996:759-756</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">9. HAYDEN DW
et al. Feline mammary hypertrophy / fibroadenoma complex: clinical and hormonal
aspects Am J Vet Res 1981 42: 1699-1703</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">10. HAYDEN DW
BARNES DM et al Morphologic exchange in the mammary gland of megestrol acetate
treated and untreated cats: a retrospective study. Vet pathol 26 1989 26:
104-113</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">11. Henik RA,
OLSON PN ROSYCHUCK, RA Progestagen therapy in cats Compend. Contin. Educ. Pract.
7 1985: 132-138</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">12. HERRTAGE
ME et al Diabetic retinopathy in a cat with megestrol acetate-induced diabetes
J.smal Anim. Pract. 1985 26: 595-601</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">13. HINTON
GASKELL Mr CJ Non-neoplasic mammary hypertrophy in the cat associated with
either pregnancy or with oral progestagen therapy Vet. Rec. 1977 100: 277-280</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">14. HOLST BS
et al Uterine pathology in cats routinely ovariohysterectomised Proccedings
EVSSAR 3<sup>rd</sup> European Congress Liege May 2002</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">15 .JOHNSON
CA Uterine disease in Textbook of Veterinary Internal Medicine of the dog and
cat ETTINGER SJ 3rd Edition, 1989: 1797-1805 27</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">16. KUNKLE GA
Progestgens in dermatology in Current Veterinary Therapy, RW Kirk, 9th Ed, WB
Saunders, Philadelphia, 1986, 601-605</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">17. Lennoz
(M) Medical contraception Proceeding National Congress CNVSPA November 2000.</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">18. Lennoz
(M) et al. Special features of the pathology of feline reproduction Prat. Med.
Anim. Comp34.1999 449-462</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">19. NELSON LW
and al Canine Mammary neoplasms and progestogens abbreviation différente JAMA
*1972 219: 1601-1606</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">20. PETERSON
ME Effects of megestrol acetate on glucose tolerance and growth hormone
secretion in the cat Res Vet Sci 1987 42: 354-357</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">21.
ROMATOWSKI J. Use of megestrol acetate JAVMA 1989 194: 700-702</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">22. OEEN EO:
The oral administration of megestrol acetate to postpone oestrus in cats,
Nordisk Veternaermedicin, 1977, 29: 287-291</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">23. Selman PJ
et al Progestin treatment in dogs Eur. J. Endocrinol. 1994 131: 413-421</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">24. Selman PJ
et al Progestin-induced GH excess in the dog originates in the mammary gland
Eur. J.Endocrinol. 1994 134: 287-292</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">25. TOMLINSON
MJ et al feline mammary carcinoma: a retrospective assessment of 17 cases Can
Vet J</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">1984 25:
435-439</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">26. WALKER EC
Oral progestagens in cats Vet. Rec. 1975 96 458</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">Other items
consulted but not cited:</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">CONCANNON PW,
VN MEYERS-WALLEN Current and Proposed methods for contraception and termination
of pregnancy in dogs and cats JAVMA 1991; 198:1214-1225</span></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">JOHNSON SD,
ROOT KUSTRITZ MV OLSON PNS Disorders of the feline uterus and uterine tubes
(oviducts) in Canine and Feline Theriogenology 2001 WB Saunders, Philadelphia:
463-471</span></div>
<br />
<div class="MsoNormal">
<br /></div>
tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-78631491839073739162018-07-05T20:07:00.000-07:002018-07-20T14:22:47.867-07:00LINKS<div align="center">
<b><span style="font-family: "arial"; font-size: large;">Links</span></b><br />
<b><span style="font-family: "arial"; font-size: medium;"><br /></span></b><b><span style="font-family: "arial"; font-size: large;"><a href="http://www.catsinthenews.blogspot.com/">Feral Cats in the News - the Feral Cat Blog !</a></span></b><b><span style="color: orange; font-family: "arial"; font-size: medium;"></span></b></div>
<div align="center">
<span style="font-family: "arial" , "helvetica" , sans-serif;">Daily, national and global cat news, info, resources to actively use </span><br />
<span style="font-family: "arial" , "helvetica" , sans-serif;">for cat advocacy and cat management.</span><br />
<span style="font-family: "arial" , "helvetica" , sans-serif;"><u><br /></u></span></div>
<div align="center">
<b><span style="color: orange; font-family: "arial"; font-size: large;"><u><a href="http://www.fairchildcat.org/">Fairchild Foundation</a></u></span></b><br />
<span style="font-family: "arial";">A T/N/R program in Berks County
Pa. with lots of good information on its site, including their experience with
megestrol acetate.</span></div>
<br />
<div>
<div align="center">
<b><a href="http://www.birthcontrolforcats.com/"><span style="font-size: large;">
<span style="font-family: "arial";">Birthcontrolforcats.com</span></span></a></b></div>
<div align="center">
<span style="font-family: "arial";">A caretaker discusses megestrol acetate
dosing, his experience, and more. </span><br />
<span style="font-family: "arial";"><br /></span></div>
<div align="center">
<b><span style="color: orange; font-family: "arial"; font-size: large;">
<a href="http://www.vet.cornell.edu/consultant/consult.asp">
Cornell Veterinary University Consultant</a></span></b></div>
<div align="center">
<span style="font-family: "arial";">An invaluable tool. Search for all possible veterinary diagnoses by inputting signs (symptoms), or
get more information on a diagnosis</span></div>
<div align="center">
<span style="font-family: "arial";">Medical terms can be researched by Googling
"define (whatever the term is)"</span><br />
<span style="font-family: "arial";"><br /></span></div>
<div align="center">
<b><span style="color: #ff8000; font-family: "arial"; font-size: large;"><a href="http://www.aspca.org/pet-care/poison-control">
<span style="color: #ff8000;">ASPCA Poison Control</span></a></span></b><br />
<b><br /></b></div>
<div align="center">
<span style="color: orange; font-family: "arial" , "helvetica" , sans-serif; font-size: large;"><u><a href="http://www.alleycat.org/"><b> Alley Cat Allies</b></a></u></span></div>
<div align="center">
<span style="font-family: "arial";">Dedicated to feral cat advocacy
- located in Washington D.C. </span><br />
<span style="font-family: "arial";"><br /></span></div>
<div align="center">
<b><span style="font-family: "arial"; font-size: large;">
<a href="http://www.bestfriends.org/" target="http://www.bestfriends.org">
<span style="color: #ff8000;">Best
Friends</span></a></span></b></div>
<div align="center">
<span style="font-family: "arial";">A no-kill sanctuary headquartered in Utah, the
organization which launched the "No More Homeless Pets" movement and
masters of focusing on the positive. </span></div>
<div align="center">
<span style="font-family: "arial";"><u><span style="color: blue;">T</span></u><a href="http://www.bestfriends.org/resources/no-kill-resources/">he
No Kill Resources area</a> has some of the most comprehensive information on
anything from starting a spay-neuter program to finding a home for a hard to
place cat. </span></div>
<div align="center">
</div>
</div>
tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-23190273968960806192018-07-04T20:02:00.000-07:002018-07-20T14:23:56.281-07:00<div align="center">
<b><span style="font-family: "arial"; font-size: medium;">Colony Observations</span></b></div>
<div align="left">
<span style="font-family: "arial";">A colony of feral cats in an apartment
complex near Orlando Florida was fed Feralstat once a week in wet cat food
beginning late spring of 2010 and ending fall of 2011. The caretaker had
been approached several times with an offer to help TNR, but he was
unresponsive. </span></div>
<div align="left">
<span style="font-family: "arial";">The complex was bordered by a vacant golf
course, a neighborhood of single family homes, and several other apartment
communities. </span></div>
<div align="left">
<span style="font-family: "arial";"><br /></span></div>
<div align="left">
<span style="font-family: "arial";">Although over time we were able to get within
several feet of the cats, it wasn't close enough contact
to observe something like mammary swelling if that was present. The cats looked
to be in good health, and were seen playing with each other. No births or pregnancies
were observed, but
two kittens did appear in the summer of 2011 which we believe were
offspring of other cats in the vicinity. It did seem that some of the cats who were "teenagers" when we began feeding them
seemed to remain that size over the year. </span></div>
<div align="left">
<span style="font-family: "arial";"><br /></span></div>
<br />
<div align="left">
<span style="font-family: "arial";">In the fall of 2011 a mother bear made
contact with a person walking her dog in the complex so Florida Fish & Wildlife
were called. Traps were set for the bear and officers began patrolling the area.
At that point we had to suspend feeding of the cats. </span></div>
<div align="left">
<span style="font-family: "arial";"><br /></span></div>
<div align="left">
<span style="font-family: "arial"; font-size: large;"><b>10/29/2010</b></span></div>
<div align="left">
<span style="font-family: "arial";"> </span><img border="0" height="150" src="https://floridacatnews.com/cats%20102910.JPG" width="200" /></div>
<div align="left">
<br /></div>
<div align="left">
<span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;"><b>12//21/2010</b></span></div>
<div align="left">
<br /></div>
<div align="left">
<img border="0" height="150" src="https://floridacatnews.com/12212010.JPG" width="200" /></div>
<div align="left">
<br /></div>
<div align="left">
<br /></div>
<div align="left">
<span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;"><b>1/30/2011</b></span></div>
<div align="left">
<br /></div>
<div align="left">
<img border="0" height="100" src="https://floridacatnews.com/013011%2004.JPG" width="200" /></div>
<div align="left">
<br /></div>
<div align="left">
<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;">2/27/2011</span></b></div>
<div align="left">
<img border="0" height="86" src="https://floridacatnews.com/02272011.jpg" width="200" /></div>
<div align="left">
<br /></div>
<div align="left">
<br /></div>
<div align="left">
<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;">4/6/2011</span></b></div>
<div align="left">
<img border="0" height="142" src="https://floridacatnews.com/04062011.jpg" width="200" /></div>
<div align="left">
<br /></div>
<div align="left">
<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;">6/5/2011</span></b></div>
<img border="0" height="131" src="https://floridacatnews.com/06052011%201.jpg" width="200" /><img align="left" border="0" height="126" src="https://floridacatnews.com/06052011%202.jpg" width="200" /><br />
<div align="left">
</div>
<img border="0" height="158" src="https://floridacatnews.com/06052011%207%20kittens.jpg" width="200" /><br />
<div align="left">
<br /></div>
<div align="left">
<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;">7/3/2011</span></b></div>
<div align="left">
<br /></div>
<div align="left">
<br /></div>
<div align="left">
<img border="0" height="150" src="https://floridacatnews.com/07032011%20nine%20total.JPG" width="200" /></div>
<div align="left">
<br /></div>
<div align="left">
<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;">8/7/2011</span></b></div>
<div align="left">
<br /></div>
<div align="left">
<br /></div>
<img border="0" height="113" src="https://floridacatnews.com/08072011%202.jpg" width="200" /><br />
<br />
<div align="left">
</div>
<div align="left">
<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;">9/19/2011</span></b></div>
<div align="left">
<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;"><br /></span></b></div>
<div align="left">
<img border="0" height="150" src="https://floridacatnews.com/09192011%202%20six%20cats.jpg" width="200" /></div>
<div align="left">
<br /></div>
<div align="left">
<br /></div>
<div align="left">
<br /></div>
tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-18419809067511075442018-07-01T20:38:00.000-07:002018-07-20T14:17:35.004-07:00Topix thread 06152015 posts 1 to 83<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post64" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#64</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Oct 26, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James,<br />
<br />
Thanks again for your advice, willing to help and sharing your meed knowledge
in helping kitties.<br />
<br />
Hope my neighbor and I will be lucky in trapping the kittens, mom and
dad cats.<br />
<br />
Thanks again,<br />
<br />
Annie<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post65" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#65</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Oct 27, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">That was supposed to
have been "meds" in my original post above...I will post info later
tonight about how to get antibiotics without a prescription for cats (and
dogs)....gotta head to work right now...will post it later.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post66" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#66</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 1, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Today I am very
happy.<br />
Both mom and dad cat have been trapped and on their way to Chicago PAW for
spay/neuter.<br />
With FeralFixers and PURR Naperville's help, this impossible task really got
done.<br />
<br />
The mom cat has seen her kittens got trapped by humane trap before.<br />
So FeralFixers suggested using drop trap.<br />
The drop trap was elevated and not set for the first 2 days so they got used
to eat under the drop trap. Then we set the trap today and trap them. We do
need hold onto the drop trap when they got trapped then transferred them to a
carrier with FeralFixers help.<br />
<br />
Now kitten traps have been set. Hopefully very soon we can rescue
thosekittens.<br />
<br />
Just like to share my experience and happiness.<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post67" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#67</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 1, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">KK: You could
actually dilute the pill down and mix it with water--I have some
goodinstructions on turning a pill into a liquid for cats if
you need the info--let me know....Take care of Emma--she sounds like a
sweetie!<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James, just a quick
update on the dosage. It seems to be working just fine. FeralStat had to
be given once a week, but I'm 9 days into the OvaBan dosageand so far so
good! No signs of "heat." Awesome! I'm so happy about this and just
wanted you to know that crushing the 1/4 tablet worked fine in her food
without diluting it, so I'll just stick to that.<br />
<br />
I did want to ask you if you're aware of kitties sort of drooling sometimes
with the OvaBan? I don't know what other word to use - but she's not walking
around and I'm having to wipe up after her! I just notice that she's
swallowing more than normal and sometimes I'll feel her little
mouth wet, or when she's got her head on my arm, I'll feel it that
way. I don't think it's a big deal; I was just wondering if you've heard
anything about that.<br />
<br />
You're helping a lot of us, James. Thank you!:-)<br />
<br />
KK<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/mobile-al"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Mobile, AL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post68" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#68</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 1, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Annie wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Today I am very
happy.<br />
Both mom and dad cat have been trapped and on their way to Chicago PAW for
spay/neuter.<br />
With FeralFixers and PURR Naperville's help, this impossible task really got
done.<br />
The mom cat has seen her kittens got trapped by humane trap before.<br />
So FeralFixers suggested using drop trap.<br />
The drop trap was elevated and not set for the first 2 days so they got used
to eat under the drop trap. Then we set the trap today and trap them. We do
need hold onto the drop trap when they got trapped then transferred them to a
carrier with FeralFixers help.<br />
Now kitten traps have been set. Hopefully very soon we can rescue
those kittens.<br />
Just like to share my experience and happiness.<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie, just wanted
to chime in and say Congrats! on trapping the cats for spay/neuter. You've
done an awesome thing - and please keep us posted on how they do and if
you're able to get the kittens! Good Luck to you!<br />
<br />
KK<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post69" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#69</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 1, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie--congratulations
on trapping the kitties! I'm so proud for you! Drop traps work great for
those kitties that have seen trap door ones before. They are smarter than you
think they are and still some people call them dumb animals. Congrats again
on your accomplishments! Keep us posted on their surgeries.<br />
<br />
KK: Emma is foaming and drooling because the medicine tastes bad. I
have given kitties meds before and if it tastes bad to them, they will foam
and drool like crazy.<br />
<br />
To prevent this, you can dilute the pills into a liquid suspension and then
dose her by using an eye dropper & get the dosage far back in
her throat to get past her taste buds.<br />
<br />
I am concerned about the dosage you listed though--1/4 tablet. If
you are using 20 mg tablets, that means you are dosing her 5 mg
once a week...this is twice the
normal dosage...normal dosage of OvaBan tablets for a colony
of 1-4 cats is 2.5 mg once a week--which would be 1/2 of a 5 mg OvaBan
tablet. Are you using 20 mg tablets? I've never seen where 5 mg once a week
for a single cat would be safe--check your dosages recommended by your vet.<br />
<br />
If you are using 20 mg OvaBan tablets, you can take TWO of them,
crush them and dissolve them both into 8 ml of distilled water. This gives
you a liquid solution of 8 ml of liquid MegAce with 5 mg of megestrol acetate
in each ml of the liquid suspension. That is, 40 ml divided by 8 ml = 5 mg
per ml. Going back and looking at the dosing chart that
Fairchild Foundation listed in the posts above, you can see that for a colony
of less than 5 cats, the dose is .5 ml once a week (notice the decimal
point)--this equals 2.5 mg of megestrol acetate per dose.<br />
<br />
If you make up the liquid suspension like this, it would be easier to dose
Emma with a syringe/eyedropper and stop the drooling.<br />
<br />
Please double check your dosages.<br />
<br />
I'll post more later on antibiotic meds if you all want me to...<br />
<br />
Thank you all for all your dedication to feral cats. I hope I have helped
some you here...I'll continue to share tips here as we need them.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post70" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#70</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 2, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Hi,<br />
<br />
Even happier today.<br />
My neighbor and I got all 3 kittens trapped around the deck area
that we think they hide.<br />
One was trapped yesterday late afternoon.<br />
We did not trap any today around 5 pm which got us very worried because the
2 kittens have no food for 2 days and the weather would become bad
starting late evening.<br />
So we put fresh chicken and moved the trap right next to the small hole we
think the kittens get out of the deck. Unbelievable, 10 minute
later, we got one trapped. Then half hour later, the 3rd one got
trapped.<br />
We put all 3 kittens in a big dog cage with chicken and water. They
all ate well but still kind of scared so far.<br />
It is so nice to see all the sibling together again inside.
We feel so relieved.<br />
<br />
The mom and dad cat will come home tomorrow.<br />
We will put the mom cat in a separate dog cage next to the kitten cage for
recovery.<br />
We believe the mom cat will feel more relaxed once she sees all her
kids are OK.<br />
<br />
All the kittens will be taken for adoption some time later.<br />
<br />
The dad cat has been taken care by my neighbor's family for 2 years and
stayed inside their house during very cold nights. So the family will take
him inside when he is back.<br />
<br />
One of the best news is that FeralFixers team (they have trapped > 3000
stray cats and do TNR in 4 years), assess that the mom cat can also be tame
for adoption. I think the mom cat being around with the dad cat for few
months really help the mom cat not to fear of human as before.<br />
<br />
I really like to take the mom cat inside my house but one family member is
not cooperative.<br />
All I care is for the mom cat to have a better life.<br />
So as long as we can find a home for her, I don't have to keep her inside my
house.<br />
<br />
Thanks all for willing to read my stories and sharing my happiness.<br />
<br />
I know everybody on this website has very good heart.<br />
<br />
Annie<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/kkdaniels" title="See KKDaniels's profile"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;">KKDaniels</span></b></a><b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/mobile-al"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Mobile, AL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post71" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#71</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 2, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">KK: Emma is foaming
and drooling because the medicine tastes bad. I have given kitties
meds before and if it tastes bad to them, they will foam and drool like
crazy.<br />
To prevent this, you can dilute the pills into a liquid suspension and then
dose her by using an eye dropper & get the dosage far back in
her throat to get past her taste buds.<br />
I am concerned about the dosage you listed though--1/4 tablet. If
you are using 20 mg tablets, that means you are dosing her 5 mg
once a week...this is twice the normaldosage...normal dosage of
OvaBan tablets for a colony of 1-4 cats is 2.5 mg once a week--which would be
1/2 of a 5 mg OvaBan tablet. Are you using 20 mg tablets? I've never seen
where 5 mg once a week for a single cat would be safe--check your dosages
recommended by your vet.<br />
James<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James, Emma's dose
is from the 20-mg tablets, but the 5 mgs or 1/4 tablet is for a span of two
weeks! And I actually gave her a little less than that. The vet said to try
it and see how she does, and so far so good. This Sunday will be two weeks.
So do you think I'm on the mark now? I did dbl-ck everything, and those are
the instructions from the vet. So now what do you think? Are we safe?<br />
<br />
On the drooling, that does make sense; but it's just so strange that she'll
sometimes drool or have a wet mouth days later. I noticed it with the
FeralStat too, James. I'll let you know what my vet says when I take her in.<br />
<br />
Thanks so much for posting the info on the eye dropper dosage. I'll keep it
just in case!<br />
<br />
KK<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post72" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#72</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 3, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">KK: You should be
fine on that 2 week dosage and if vet told you that, then all is fine--I
misunderstood your post & thought you were doing 5 mg once a
week...you're good to go! Keep us posted on Emma.<br />
<br />
Annie: Congrats on the trapping of all the kitties---your dedication &
patience paid off--a job well done!! It does feel good when one can trap all
of the kitties of a litter in such a short time span & with winter coming
on, it is beneficial for all involved.<br />
<br />
You are blessed to have FeralFixers--they sound like a great organization.
God bless you for taking on the task of saving those babies &
parents...keep us posted on the adoptions.<br />
<br />
My personal thanks go out to you for your dedication & perseverance in
saving them! Thank you!<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post73" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#73</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 10, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Hi,<br />
<br />
Just like to give an update on the mom cat and 3 kittens.<br />
The mom cat lives in one of bathroom now. She is still shy and hides in one
isolated corner most of the time. Her facial expression looks much different
than we just trapped/spayed her. She meows to me and blinks her eyes. She
still ate the food when I was not around.<br />
Once she is more comfortable in the bathroom, I will let her wander on the
second floor rooms.<br />
<br />
The 3 kittens are also spayed/neutered and received necessary medical
treatment.<br />
I just moved them from garage to my master bedroom bathroom, but all are in
different cages.<br />
FeralFixers lady told me to let them get used to the room first before taking
them out to play. So I plan to take them out to play this weekend.<br />
Once they are more used to home environment and people, they would become
ready for adoption.<br />
<br />
For the mom cat, I will keep her in my house for some time and eventually will
be adopted by one of my colleages who is a very nice and decent person.<br />
<br />
Thanks for listening to me.<br />
<br />
Annie<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post74" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#74</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 11, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks for the
update Annie. Sounds like the kitties are doing fine. You've done it exactly
like I have done many times in the past--keep the babies in a kennel cage for
a few weeks until they tame down--take them out & play with them
periodically. They will come around after 2-3 weeks & tame down. Mama
kitty will take more acclimating, but she will "slowly" trust you
over time--careful trying to pick her up though. Keep us updated periodically
on how they are coming.<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post75" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#75</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 11, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">KK: You should be
fine on that 2 week dosage and if vet told you that, then all is fine--I
misunderstood your post & thought you were doing 5 mg once a
week...you're good to go! Keep us posted on Emma.<br />
James<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thank you for
confirming the dosage, James. I will keep you posted on how my little
sweetie-pie does.<br />
<br />
Wow, Horay! for Annie and what she's accomplished! I love a great story and
even better ending!<br />
<br />
KK<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/daphne-al"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Daphne, AL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post76" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#76</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 11, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Annie wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Hi,<br />
Just like to give an update on the mom cat and 3 kittens.<br />
Annie<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Congratulations,
Annie! Sounds like your new house guests are very lucky! It seems like you've
got a great plan, and I really hope you can find them awesome homes. After
going through all this, it's just got to happen that things will fall into
place.:o)<br />
<br />
KK<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post77" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#77</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 14, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James and KK,<br />
<br />
Thank you so much for encouraging and advising me.<br />
<br />
Like to share one mistake that I made over the weekend. After I enjoyed
watching all the kittens playing together in my master bathroom, I decided to
let their mom see them hopefully to help relax their mom.<br />
<br />
I felt quite emotional while watching them meet and show love to each other
when I just put the kittens in the hallway bathroom with their mom.<br />
<br />
When I returned back to the hallway bathroom, the mom cat growled and hissed
at me. At that moment, I realized that I made a mistake helping them revert
back to wild life treating my hallway bathroom as their territory.<br />
<br />
It took quite a lot effort to grab all the kittens and put them back to the
master bathroom because 2 of them were completely leaned on their mom (my
husband was using carboard to divide them).<br />
<br />
Glad that both the mom cat and kittens behaved the same way as before their
reunion.<br />
<br />
One of the kittens who got trapped first is an easy going kitten and pretty
much ready for adoption.<br />
The other 2 are still kind of scared when I let them out of the cage.<br />
Will continue working with the kittens an<br />
d the mom cat.<br />
<br />
Thanks,<br />
<br />
Annie<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/kkdaniels" title="See KKDaniels's profile"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;">KKDaniels</span></b></a><b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/daphne-al"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Daphne, AL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post78" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#78</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 14, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Annie wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James and KK,<br />
Thank you so much for encouraging and advising me.<br />
Like to share one mistake that I made over the weekend.<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Hi, Annie!<br />
<br />
One thing to remember is that we learn from mistakes. And I wouldn't even
look at it as a mistake, really, but just trial and error. You tried and
realized that the timing was off and it didn't quite work out like you would
have hoped! And I'm sure James would have far better useful advice than I,
but don't be discouraged. You just keep up the good work, and I'll bet they
all come around just like they need to. How can they not respond to the
nurturing, care, and love you're showing them! I think that's in not only our
nature, but theirs as well.<br />
<br />
One thing my vet does where I live is he'll let people post any adoption pets
on a bulletin board in his lobby. You may try that when it's time to try and
find them a home, and I see a lot on Craigslist too.<br />
<br />
I enjoy all the updates. Obviously, I'm a succer for pets and stories with
great endings, so please keep us posted!<br />
<br />
KK<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Yvette<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">AOL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post79" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#79</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 16, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Im from Ontario
Canada and am panicking over here. I had a prescription from a Dr. Heller via
Feralstat and I'm almost out. Has anyone heard how Canadians might be able to
access a prescription from a U.S. vet over the phone?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Gail from Hilltop
Humane<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/abington-ma"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Abington, MA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post80" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#80</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 18, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">When someone
suggests posting animals for adoption on Craigslist, it makes me nervous. I'm
sure all of you are very careful in researching potential adopters for the
animals you rescue but I just want to remind everyone not to post
"Kittens Free to Good Homes" ads or the like. Always charge at
least $25 to make sure the adopters place a value on the animal. Free animals
are more likely to be neglected or abandoned because people think
"there's more where that came from." Worse still, free kittens are
sometimes fed to pet snakes and free dogs used to teach fighting dogs to
kill. Your local shelter can give you a questionnaire to use when screening
potential adopters. If they rent, check with the landlord if they are allowed
to have pets. Talk to their vet is they are already pet owners. Make sure
they have the money to properly care for a pet--food, vet bills, etc.
AND--most important--make sure all animals are spayed or neutered before they
go to a new home. Your local shelter may be able to help with the expense or
direct you to a low cost clinic or have the adopter pay for the surgery
before you release the animal to them. I know I'm a worry wart but you can't
be too careful. And the only way to impact animal homelessness is through
spay and neuter. Thanks for helping!<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post81" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#81</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 18, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">KK,<br />
Thanks much for the encouragement and suggestion.<br />
<br />
Also like to thank Gail for the warning and headup.<br />
<br />
FeralFixers team will help evaluate on when the kittens are ready for
adoption then they probably will go through PURRS Naperville for adoption.<br />
<br />
After taking care of the kittens for 2.5 weeks now, I do want to make sure
the kittens will end up with a nice home/owners.<br />
I like to come up some adoption considerations based on the kittens'
temperament and status.<br />
2 out of the 3 kittens are more careful and fearful of people than the other
one.<br />
It would be good if both can go to the same home as a company so they can
adjust better. They play so happily together. It would be great if all 3 can
stay together, but I really can not expect that.<br />
<br />
Thanks again,<br />
<br />
Annie<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">clyde<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post82" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#82</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 18, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Thanks for the
update Annie. Sounds like the kitties are doing fine. You've done it exactly
like I have done many times in the past--keep the babies in a kennel cage for
a few weeks until they tame down--take them out & play with them
periodically. They will come around after 2-3 weeks & tame down. Mama kitty
will take more acclimating, but she will "slowly" trust you over
time--careful trying to pick her up though. Keep us updated periodically on
how they are coming.<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">......JAMES CAN YOU
GIVE ME AN E-MAIL ADDRESS TO WHERE YOU ARE GETTING YOUR MEDICATION FROM..IF
YOU LIKE YOU CAN E-MAIL ME PERSONALLY AT jaspertowncryer@yahoo.com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p4"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post83" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#83</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 19, 2011</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie, you are doing
great!! Keep up the good work and keep us posted on the kitties. I know it
would be great if you could keep all 3 together, but I too have been in your
situation many times & you just can't always keep the babies
together--they will make someone good pets, all thanks to your kindness and
diligence in giving them a good home & bettering their lives. Keep on
posting updates! Happy Thanksgiving!<br />
<br />
Yvette: I wish I could help you in your plight in Canada, but you are going
to have to find a vet there that will hear your plight and prescribe you some
megestrol acetate in pill form or liquid Megace. I seriously doubt that any
vet will now prescribe these over the phone without you being a
"customer" of theirs. I suspect this is what may have happened to
FeralStat--that is, they got caught up in prescribing too much medicine just
over the phone, but again, I don't know this.<br />
<br />
Clyde: I wish I could help you. The vet I receive my megestrol acetate from
is a LOCAL vet that I have spent 1000's of $$ with over the years for my cat
& dog needs. You will need to establish a working
"doctor/client" relationship with a local vet in your area like I
and KK have done in order to get a scrip for MA. I know of no vet that will
sacrifice their vet license for "phone in" prescriptions for
megestrol acetate for feral caregivers. Again, I really suspect this is what
happened to FeralStat Inc, but I don't know for sure. The FeralStat method of
calling in and getting FeralStat reminded me of the "diet doctors"
back in the 90's that would prescribe fen-fen on the fly & would have
"patients" lined up out the door to be herded in like cattle each
month for their prescriptions.<br />
<br />
With all the information that I & others have posted here in the last
couple of months on alternatives to FeralStat and correct dosage, it is not
hard to establish a doctor/client relationship with a good vet of your
choice, explain to them your plight as a feral caregiver, educate the vet on
the use of megace if necessary and have them prescribe you a bottle of
megestrol acetate pills. A bottle of 100 is cheap in comparison to what we
have paid for FeralStat in the past..plus a bottle of 100 pills can be broken
down and will last a very long time for feral caregivers. See posts above for
dosage.<br />
<br />
All past and future posters here looking for FeralStat need to realize that
the days of "calling up a long distance doctor like Dr. Heller for
feralstat/alternative" are over--plain and simple. You MAY can find some
overseas company that will do this, but it is best to follow protocol like I
and others here have done to obtain a FeralStat alternative.<br />
<br />
Also, let's not forget that MA is not a solution to feral overpopulation--it
is only temporary to allow feral caregivers to get ahead on their TNR
programs.<br />
<br />
Happy Thanksgiving to all good people here...as well as Ms. Emma Kitty and
Mama Kitty and her 3 babies!<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">es<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post44" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#44</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Don't know what happened on the
multiple postings.....<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post45" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#45</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thank you, James!<br />
<br />
I will definitely be doing some follow up on this and I will let everyone
know. I am putting together a package of information for my own vet and
hoping to get her on-side so I can obtain the necessary ovaban from her. The
above information will help immensely.<br />
<br />
Thank you!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">phyllis gutman<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">AOL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post46" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#46</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 17, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">leslie leavitt wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">I have used
FeralStat on a feral colony for about 2 and a half years. Have not had one
kitten born in that time. The cats appear to be healthy. I will continue
to use it despite negative comments. The life of a feral is hard at best.
They are already subject to all kinds of illnesses and diseases and
while the thought of adding to their troubles with FeralStat is not my
intention I will continue to use it. Preventing feral kittens from being born
is my goal at this time. I have tried many times to trap these cats but they
are very trap wary.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Where do you get it? there used to
be a doctor that manufactured it but he died. How much do you use for 1 cat
that keeps getting pregnant? Please reply. Thanks.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">phyllis gutman<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">AOL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post47" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#47</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 17, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Where do you get it? How much
would you use for 1 cat that keeps getting pregnant. Please reply. I have
some from a while ago.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/kkdaniels" title="See KKDaniels's profile"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.5pt;">KKDaniels</span></b></a><b><span style="font-family: "times new roman" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/daphne-al"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Daphne, AL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post48" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#48</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 20, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi there, James!<br />
<br />
I wrote a long note yesterday explaining my recent visit to the vet
regarding Emma and the hernia and her heat cycles, but after all
that, it didn't post!!!<br />
<br />
So I'm making this one shorter just in case it happens again. But I wanted to
thank you for the information you found. I know this has been a big help to
me and many others re the MA or Ovaban. My vet had heard of it but didn't love
the idea for Emma and her "issues." Not long-term anyway. But he
did prescribe it for her until I decide what to do about the surgery, which
I'll probably do after the holidays as there's so many complications
and side effects that can arise from the MA, but especially with
her issues!<br />
<br />
But I wanted to ask you if you think I should dissolve the crushed tablets in
water as it had mentioned on the site you referenced? I have the 20 mg
tablets, which I'll have to quarter and use less than a quarter every two
weeks to see how that works for her. He said let's start out with less and
see if it'll work first. So I'm just so thankful that I learned of this site
and came across such helpful and caring people such as yourself. I'm very
grateful!<br />
<br />
Oh, and for 10 tablets, it was $11; and I know it would have been
cheaper had I gone to Target or Wal-mart, but I used Walgreen's on the fly.
So that should give me about 10 months worth, I believe. I really wish I had
known of this before now as I'm sure a lot of other people feel the same way!
I just other vets will be open to the idea for feral cats.<br />
<br />
I'd love to hear back from you again on dissolving the tablets and the
dosage, if you're around. And if I could reach you, I'd give you a big hug!!!
Thanks again, James! Emma thanks you too!<br />
<br />
KK<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ken<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/slippery-rock-pa"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Slippery Rock, PA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post49" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#49</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">kcook924 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Did the FeralStat
work?<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I've been using since July 2010
and have had no new kitties. All cats in my colony are healthy and going
strong!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ken<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/slippery-rock-pa"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Slippery Rock, PA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post50" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#50</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Here is what I got from an email I
sent on 10/20.<br />
It is with regret that I inform you the FeralStat office is closed and we
cannot provide your refill at this time. We are devastated by the impact the
lack of this product will have on feral colonies like yours and we are exploring
all options for making it available again as soon as possible.<br />
Please check back with us in a few weeks for a status update.<br />
Sincerely,<br />
Donna Sicuranza<br />
President<br />
FeralStat, Inc.<br />
I am seriously bummed! FeralStat has kept my colony at the same level for 2
years. I don't know what is going on but I am seriously ticked off.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ken<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/slippery-rock-pa"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Slippery Rock, PA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post51" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#51</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">KKDaniels wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Hi there, James!<br />
I wrote a long note yesterday explaining my recent visit to the vet
regarding Emma and the hernia and her heat cycles, but after all
that, it didn't post!!!<br />
So I'm making this one shorter just in case it happens again. But I wanted to
thank you for the information you found. I know this has been a big help to
me and many others re the MA or Ovaban. My vet had heard of it but didn't
love the idea for Emma and her "issues." Not long-term anyway. But
he did prescribe it for her until I decide what to do about the surgery,
which I'll probably do after the holidays as there's so many complications
and side effects that can arise from the MA, but especially with
her issues!<br />
But I wanted to ask you if you think I should dissolve the crushed tablets in
water as it had mentioned on the site you referenced? I have the 20 mg
tablets, which I'll have to quarter and use less than a quarter every two
weeks to see how that works for her. He said let's start out with less and
see if it'll work first. So I'm just so thankful that I learned of this site
and came across such helpful and caring people such as yourself. I'm very
grateful!<br />
Oh, and for 10 tablets, it was $11; and I know it would have been
cheaper had I gone to Target or Wal-mart, but I used Walgreen's on the fly.
So that should give me about 10 months worth, I believe. I really wish I had
known of this before now as I'm sure a lot of other people feel the same way!
I just other vets will be open to the idea for feral cats.<br />
I'd love to hear back from you again on dissolving the tablets and the
dosage, if you're around. And if I could reach you, I'd give you a big hug!!!
Thanks again, James! Emma thanks you too!<br />
KK<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">What tablets are you purchasing?
Did you need a prescription?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post52" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#52</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Does anyone have any feral stat
left. If I can get a sample I may know a vet that can fix this for
us. Let me know.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p3" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post53" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#53</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 22, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Ken wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"><quoted text><br />
What tablets are you purchasing? Did you need a prescription?<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ken, read back a few post where
James explains the MA or Ovaban. Yes, I went to my vet and he called in an RX
for me for my cat. It's so, so much cheaper than FeralStat too. Granted, we
have to break it down and measure it ourself, but it's a fix! Ask your vet,
and if he can't help, find one who can!!! The tablets are Megestrol Acetate,
I believe the same ingredient in FeralStat and Ovaban, and I have
the 20 mg. I should be able to break mine down to get 8 weeks of protection
out of one tablet (for one cat). Let us know what you find out! Good luck,
and thanks for posting about FeralStat news!<br />
<br />
KK<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post54" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#54</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 24, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">KK< I'm glad you found some
OvaBan for your predicament and I hope it helps Emma too! As for dissolving
OvaBan in water, I would try just crushing the dosage up and mixing in food
rather than using water. The water method is actually for LIQUID MegAce in
which you dilute it with 5 ml of distilled water. But if you have the OvaBan
tablets, just crush the amount needed and place in canned food as outlined on
site above.<br />
<br />
Below will be the dosages for those of you using OvaBan Tablets at 5 MG PER
TABLET. KK, I know you said you got 20 MG tablets from your Vet, so remember
that 1/4 of a 20 MG tablet will be equivalent to (1) 5 MG tablet in the
chart below.<br />
<br />
Do NOT overdose--the chart below is based on 5 MG per tablet of
OvaBan--adjust dosages below for your strength of OvaBan. For those of you
who keeping asking where to get this, go back and READ ALL POSTS THAT KK
& I HAVE HERE--the information is all there.<br />
<br />
Here's the dosage for OvaBan TABLETS, 5 MG PER PILL:<br />
<br />
If you are using the OvaBan TABLETS at 5 mg per tablet instead of the generic
liquid human MegAce, use the chart below for
proper dosing of feral cat colonies.Remember, 1 tablet = 1 ml. in
this case.<br />
<br />
Dosing Chart For Feral Colonies Using 5 Mg Tablets Of OvaBan Crushed
& Mixed In Food. 1 Tablet = 1 ML.<br />
<br />
Total Number of Cats in the Colony - Dosage per colony /
Frequency<br />
<br />
< 5 cats .5 ml ONCE a week =½ of a 5 mg OvaBan Tablet Crushed & Mixed
In Food<br />
<br />
5-7 cats 1.0 ml ONCE a week = 1 OvaBan (5 mg) Tablet Crushed & Mixed In
Food<br />
<br />
8-11 cats 1.5 ml ONCE a week= 1 ½ OvaBan (5 mg ea.) Tablets Crushed &
Mixed In Food<br />
<br />
12-15 cats 1.0 ml TWICE A WEEK = 1 OvaBan (5 mg) Tablet Crushed & Mixed
In Food<br />
<br />
16-19 cats 1.5 ml TWICE A WEEK= 1 ½ OvaBan (5 mg ea.) Tablets Crushed &
Mixed In Food<br />
<br />
20-23 cats 1.6 ml TWICE A WEEK = 1& 2/3 OvaBan (5 mg ea.) Tablets Crushed
& Mixed In Food<br />
<br />
24-27 cats 2.0 ml TWICE A WEEK=2 OvaBan (5 mg ea.) Tablets Crushed &
Mixed In Food<br />
<br />
28-31 cats 2.2 ml TWICE A WEEK=2 ¼ OvaBan (5 mg ea.) Tablets Crushed &
Mixed In Food<br />
<br />
32-35 cats 2.5 ml TWICE A WEEK= 2 ½ OvaBan (5 mg ea.) Tablets Crushed &
Mixed In Food<br />
<br />
1) The crushed OvaBan MUST be mixed in CANNED cat food and served on multiple
plates or dishes (NO PAPER). Use one 5.5 oz can of cat food for every 3 cats
in your colony. It is very important to spread it out on as many plates as
possible so the entire colony is being medicated as evenly as possible.<br />
<br />
2) Divide the appropriate dose of medication for your colony evenly among the
plates of food and mix it thoroughly into each plate of food.<br />
<br />
3) DO NOT DISPENSE IN MILK OR MILK PRODUCTS!<br />
<br />
4) DO NOT SKIP OR MISS A DOSE! If you were unable to dose the cats on your
scheduled day, do so on the very next day and resume your schedule the
following week. For colonies that require a frequency of 2 times per week,
the dosages MUST be spaced out.<br />
<br />
WARNING! If you use more than the dosages listed in the charts, the cats can
develop breast tumors. Many feral care givers tend to overdose.<br />
IF YOU FOLLOW THE DIRECTIONS & USE THE DOSAGES IN THE CHARTS BASED ON
YOUR COLONY SIZE, ALL WILL BE FINE! Contrary to popular belief and opinion on
the Internet, megestrol acetate has been FDA approved for use in cats. Remember,
the use of contraceptives in feral colonies is is NOT a permanent solution to
the growing animal problem. Using OvaBan, MegAce or FeralStat will allow the
feral colony care givers to gain an edge on the reproductive cycles as they
TNR the colony. Continue to TNR the colony until all cats have been spayed
and neutered.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Carol<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/dallas"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post55" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#55</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 24, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James - this information is great!
Thank you so much! Do you know of any vets who are comfortable prescribing
through a phone interview process? I am unable to locate any here in the
Dallas area at this time and I'm eeking out my last dose of FeralStat this
weekend. I only have a small colony (we've gone from 12 to 6 over two years
thanks to FeralStat and then natural lifespan), but 4 of my 6 are female!<br />
Again,THANKS!<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post56" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#56</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 24, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">KK< I'm glad you
found some OvaBan for your predicament and I hope it helps Emma too! As for
dissolving OvaBan in water, I would try just crushing the dosage up and
mixing in food rather than using water. The water method is actually for
LIQUID MegAce in which you dilute it with 5 ml of distilled water. But if you
have the OvaBan tablets, just crush the amount needed and place in canned
food as outlined on site above.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James, thanks for chiming in on
the dosage and clearing that up for me. I thought that might be the case, but
I wanted to be sure. This is really going to help Emma and me in our pinch
right now, so thanks again!!! Maybe I'll let you know how she does with her
surgery after the holidays!<br />
<br />
I hope others who are keeping up with this thread can find OvaBan in their
area for the ferals they're trying to help.<br />
<br />
KK<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post57" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#57</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 24, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi,<br />
While I am following up this thread to get Ovaban for a female stray cat
which just had her second litter this year on 9/1/11 and now she seems
pregnant again (her belley looks bigger than after her delivery on 9/1).<br />
Can Ovaban still be given to her if she does get pregnant again?<br />
Please help.<br />
thanks,<br />
Annie<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post58" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#58</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 24, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Carol: I don't know of any vets in
& near Dallas that will do that over the phone. It probably is going to
take an actual trip to the vet to TALK to a vet in person & explain
situation--many vets do not know about FeralStat & Meg acetate for controlling
estrus in cats. Educate them a little--point them to the Fairchild Foundation
link above--and I'm sure they will write you a scrip for OvaBan--you'll have
better luck with paying the office visit fee or better luck with small suburb
vets near Dallas rather than big city ones--just a thought. If you have
family in small towns, have them check with their vets and explain situation.
If you go in person it may not hurt to wear a Texas A&M University shirt
as many vets in TX graduate from there.:)<br />
<br />
Keep digging and do a little social engineering and you'll find a vet who
will prescribe OvaBan or MegAce. A 240ml bottle of MegAce is running about
$30.00 at my pharmacy now--pretty cheap once you dilute it down and use as
directed--MUCH cheaper than FeralStat--it would be worth your while to make
an appointment with a vet, pay the consulting/office fee if any, and get a
scrip for MegAce or OvBan--will save you money in long run over price of
FeralStat. Check with rescue group owners and see if they have experience in MA/OvaBan.<br />
<br />
KK: You could actually dilute the pill down and mix it with water--I have
some good instructions on turning a pill into a liquid for cats if you need
the info--let me know....Take care of Emma--she sounds like a sweetie!<br />
<br />
Annie: FeralStat's website originally said it was OK to dose in pregnant
cats..I'd get some OvaBan or MegAce generic--better yet, try to trap her
& get her fixed--much cheaper in long run than FeralStat or dosing to
control estrus. Remember, use of these drugs is TEMPORARY and should not
replace spay & neuter.<br />
<br />
GINGER: I do actually have some FeralStat left that I am saving for future
analysis if need be, but I am certain that this is no longer necessary due to
the information posted about OvaBan and MegAce from Fairchild Foundation.<br />
<br />
I actually think that FeralStat was just a minuscule dose of megestrol
acetate mixed with powdered lactose for taste--there can't be much more than
that in it. If you know of someone professional that would like to analyze
it, let me know.<br />
<br />
There are many ways cat owners can save money on vet bills in this
recessionary time...we all have the whole world at our fingertips with our
PCs and Google...<br />
<br />
If anybody else has questions regarding cat health, post here--maybe we can
all help each other out.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post59" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#59</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 24, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James,<br />
<br />
Thanks so much for responding and advice.<br />
<br />
Next week my neighbor and I will try to trap the kittens that are about 7
weeks old now, but we are not sure how many kittens survive and where she
hides them since she has moved them several times.<br />
<br />
It would be very hard to trap the mom cat, but we will try if we can trap her
kittens first.<br />
<br />
Assuming she is about 3 or 4 week pregnancy again, if we feed her Ovaban,
what would happen to her pregnancy?<br />
Will her pregnancy continue or terminate by discharge?<br />
<br />
From some website, it mentions small litter or dead puppies if pregnant cat
receives Ovaban.<br />
<br />
Do you recall any information from old FeralStat website on this?<br />
<br />
I am very desperate since I worry so much that the female cat is not able to
survive with the pregnancy or deliver kittens in cold December Chicago
weather and the kittens may not be able to survive in cold outside either.<br />
<br />
Hope to hear from you again.<br />
<br />
Thanks so much,<br />
<br />
Annie<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post60" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#60</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 25, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie, FeralStat or OvaBan will
NOT terminate the pregnancy if consumed by a pregnant kitty. If you use the
"WayBack Machine" at:<br />
</span><a href="http://www.archive.org/web/web.php" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.archive.org/web/web.php</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
Go there and type in </span><a href="http://feralstat.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">feralstat.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> and click "Take Me Back" and you can see
archived copies of the now defunct </span><a href="http://feralstat.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">feralstat.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> web site--click on FAQs and you will they address
the issue of FeralStat eaten by pregnant kitties.<br />
<br />
I have never seen a website speak of dead puppies--a LOT of the "chat
room" negativity towards FeralStat and megestrol acetate use came from
the fact that users of these products have OVERDOSED and NOT followed precise
instructions as far as dosage is concerned. FeralStat will cause tumors IF
OVERDOSED. Dedicated users of FeralStat & MA/OvaBan report ZERO problems
as long as directions are followed for proper dosages...users here report
zero problems as well.<br />
<br />
Yes, Chicago winters will be tough on a feral mother--maybe you can get her
trapped quickly and abort the litter via spay. Good luck!<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post61" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#61</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 25, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James,<br />
<br />
Thanks so much for digging out the defunct </span><a href="http://feralstat.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">feralstat.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> FAQ
which has the answer to my question.<br />
<br />
My neighbor and I will try to trap the kittens next week. I think the worse
case, we hope we can bring the feral mother inside for delivering the new
litter - we got to try even we know it would not be easy to accomplish.<br />
<br />
The following website states that Ovaban use in last half of pregnancy dog
may result in small litters and dead puppies:<br />
<br />
</span><a href="http://www.bobmckee.com/Client%20Info/Reproduction/ovaban.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.bobmckee.com/Client%20Info/Reprodu...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
James, really appreciate your help.<br />
<br />
I am very glad to be involved with this discussion group with people who are
so willing to help the homeless cats/kittens.<br />
<br />
Annie<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post62" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#62</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 26, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I used feralstat for 4 years and
it has been very successful for me. I am getting really nervous about not
having it anymore. I, too, am getting no information on what is going on with
the feralstat. I am writing Dr. Heller a letter and hope that I get a
response from him. I looked up the Fairchild website and it looks like they
do not send ovaban to addresses outside of PA. I am very pleased with this
lead and will pursue it.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post63" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#63</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 26, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie, I admire you & friend
for trying to help the feral mother cat--it will be tough acclimating her to
an indoor environment to have her litter. She MAY not be pregnant yet since
it hasn't been too long since last litter. For your sake I hope she's not
& maybe you can trap her as well. It's possible she may be just gaining
weight after having last litter...think positive.<br />
<br />
Good luck with the TNR of the kittens.<br />
I am doctoring some kitties now with Ivomec to control ear mites & other
problems.<br />
<br />
Contrary to my vet's belief, I have now tamed my ferals to point that I can
catch themj and administer meeds to them.<br />
<br />
And speaking of meeds for cats, I'm sure you all know about how to get
antibiotics for your cats & dogs without a prescription--use aquatic fish
meds--they're same as prescription meds but no scrip needed...I can elaborate
more if you all need more information on antibiotics without a prescription...I'm
glad to help people with info that are helping kitties....<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Cres - Minnesota<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post21" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#21</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 14, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have used FeralSTAT for two
years and our ferals are healthy. No new kittenseither. I, too, tried to
re-order as I used up my last packet last week. The webpage for FeralSTAT is
now no longer available. I googled Dr. Caltabiano, who is the vet who has
been working with this and mobile TNR. It appears he passed away
from cancer Nov.6, 2009, right after I spoke with him in September.
I had no idea. He had received a $500,000 bequest from Vernon A. Tait and
started up FeralSTAT, and became president of TAIT's Every Animal Matters.
(TEAM). Prior to this, his All-Animal Adoption non-profit foundation was
bankrupt. So it makes me wonder if, after his death, the estate finally got
tied up in legal matters, or if the funding has finally been depleted.
Either way, I'm panicking as you all are and am now looking to Animal Ark to
see if they have expanded their TNR program to our nothern area. I hate to
see our population expand after finally getting it under control. While I
don't have 60 cats, I've seen 19 litters from one kitty in the past 10 years.
She is now fixed through TNR and really healthy and happy as is her daughter.
And the other cats I haven't TRN'd are really healthy being on FeralStat. I
hope we'll be able to come up with another solution. I imagine that with this
economy, more cats will be abandoned and become feral. Good luck to you all.
There has to be a special place in heaven for those who have a heart for
homeless (and wild) kitties. Take care.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Teresa<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/sale-city-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Sale City, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post22" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#22</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">How much megestrol acetate would
you mix into the food. I think I can find this. And do you do it 12 months a
year...some of the posts indicated they used is at certain times of year?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Mary from Texas<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/nederland-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Nederland, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post23" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#23</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 17, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Kathryn wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">megestrol acetate -
that is the name of the product in feralstat.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I too have been giving my feral
colony feralstat for over a year and now can't get it. Not only that can't
find out why. I personally feel $$$$ and cetain organization(s) may be
blocking the continued sale of this product that does so much for these
poor homeless not wanted animals. I just want to find out who or what agency
is blocking this product and why. I will continue to search this out but I
feel if all of us who are interested in this product and feel betrayed
because of some personal greed of a particular organization or individual
should band together and work in force rather than individually we could
possibly find a positive solution to our problem. After all we are just
trying to be kind and caring.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/fort-bragg-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Fort Bragg, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post24" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#24</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 18, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I too have tried calling for
feralstat, and have used it successfully for over 2 years - if anyone knows
how to find it again, please let me know. I am going to try to see if a local
vet will prescribe something. IT does sound as though the man who invented
the feralstat drug has died and there is some conflict within the estate.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Cres - Minnesota<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Saint Paul, MN<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post26" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#26</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 27, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Regarding the amount of megestrol
acetate:<br />
My packaging says for a colony of 7 cats 3.5 GM per packet...also,
check on the outside of your large silver packet it was shipped in. Just NOW
noticed a number to maybe call for refill.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Cres - Minnesota<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Saint Paul, MN<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post27" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#27</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 27, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Well, that didn't work (calling
the number) They can't do anything because they work directly with FeralStat.
I asked what happened with FS, and they said they have to get some things
straightened out. I asked them if they'd like a couple of kitties in the
spring...LOL.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post28" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#28</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 27, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I looked at my packet of
FeralStat--it says 7 GM per packet for a colony of 14 cats, so now we see how
they are breaking it down "per # of cats". Also, looked on my
prescription label it says "1 mcg/mg".<br />
<br />
I am ASSUMING that this is "1 microgram (mcg) per milligram (mg) of the
megestrol acetate, since there is a very MINISCULE amount of megestrol
acetate per packet--most of the 7 gm packe is the powdered lactose/milk
additive that the vet added for "good tasting" purposes only to
help the cats want to eat it.<br />
<br />
If you email info@feralstat.com you get an email back saying to check back in
a few weeks.. I know this has happened before--that is, the vet would not
take orders for a while...not sure why this happens, but I have NEVER seen
the</span><a href="http://feralstat.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">feralstat.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> web site down like it is now.<br />
<br />
If you want to see the "old" Feralstat web site, use the
"Wayback Machine"--that is go to:<br />
</span><a href="http://www.archive.org/web/web.php" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.archive.org/web/web.php</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
Then type in </span><a href="http://www.feralstat.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">www.feralstat.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> and click "take me back" you will see
archived copies of the site to see how the original site talked
about small amounts of megestrol acetate in each dosage, etc.<br />
<br />
If you email TEAM (Tait's Every Animal Matters) who actually has the website
registered to them, they say they have NOTHING to do with FeralStat site and
they direct you to info@feralstat.com<br />
Strange indeed! Someone is lying and I don't think it is the "WHO
IS" internetlookup site!<br />
<br />
I did google and find out Dr. John Caltabiano's parter who helped
"co-invent" FeralStat with him was named Donna J. Sicuranza of
Westbury, CT. She was also on board of TEAM as well. Caltabiano passed away
in 2009 from cancer. Donna Sicuranza also had a company called "The
Dohnna, LLC"--googling that will show some info on her as well--not sure
what "The Dohnna, LLC" is.<br />
<br />
The doctor that filled my last prescription of FeralStat was named Arthur B.
Heller on the label.<br />
<br />
If FeralStat is out of business, I am sure we all can find a vet that will
prescribe OvaBan for us to control ferals. I found a very interesting article
put out by professional show cat fancy breeders in which they have been using
OvaBan to control heats for YEARS here in USA--long before FeralStat came on
market. The article lists the dosage cat breeders give to their
prized cats to control heats for 18 months or more--I seriously doubt these
breeders would be putting their prize animals at risk if megestrol acetate
was so "bad" for them like the naysayers of FeralStat say.<br />
<br />
Anyway, as feral cat caretakers, I'm sure we all can find a replacement for
FeralStat, possibly cheaper too once some vets are "educated" about
OvaBan--seems like many of today's vets don't know what OvaBan is.
"MegAce" is the human form of megestrol acetate--usually given
to cancer patients in 40 mg tablets.<br />
<br />
Anyway, the answer is out there if we all keep digging...and
hopefully, maybe FeralStat site will come back--just wish we could find
SOMEONE to talk to at FeralStat to see what's going on--we are all in limbo
now!<br />
<br />
Keep digging...<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Deborah Jerry<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/chisholm-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Chisholm, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post29" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#29</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 28, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I was using feralstat for about a
year. No new kittens & the cats looked very healthy. Tried
calling for a refill. A recording said to try back in a few weeks. Have been
trying to find out what is going on. No sucess. I took the package that
feralstat came in to my veterinarian. They did some checking & called
thatpharmacy but they would not give my veterinarian the other
ingredients. So was out of luck there. I sent Feralstat, inc. a letter. Told
them it worked great & that other people were trying to get more too. We
live in a rural area so I am going to send letters to other veterinarians in
bigger cities to see if they can come up with anything. Probably will take me
a little time, but if I find out anything I will let people know.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">KK Mobile Al<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post30" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#30</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 28, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I just tried calling FeralStat
today only to find nobody answering as well. I spoke with Dr.
Heller eight months ago, when I ordered my first RX, and I tried leaving him
a message but haven't heard anything yet. My situation is a bit different
than most in that I only have one kitty on FS. I found her on the side of the
road at eight weeks old, so I brought her home; then I noticed her breathing
was compromised, so I took her to the vet the next morning only to find out
that she has a diaphragmatic hernia, hence created the issue of not being
able to have her spayed as the surgery is too risky and I may lose her. So
that was a year ago. I took her to the vet just last week for another x-ray,
and he feels we can wait and that she may not ever get any worse; that if we
do the surgery, we may lose her - but we just don't know either way. So what
to do!!! It's driving me nutso, and she's my little heart. Now I may have to
rethink everything. I can't bear to see her going in and out of heat every
couple weeks like I did before. It's not healthy for her at all! She's
strictly an inside kitty, and when she was in heat before, before I found out
about FS, it was often, just so sad. Male cats hanging around the door and
her chasing us around the house! Poor little thing. So this is my dilemma.
The couple vets I've been to here where I live, they have never heard of FS
and offered no other ideas or meds similar to FS. If anyone hears anything at
all, please let us know; and I'll post anything I hear, if I hear from Dr.
Heller.<br />
I have read all your stories about what you do and what you go through for
the feral colonies. Kudos to everyone of you; you are amazing! If the kitties
could thank you, I'm sure they would! It takes special people to do what you
do!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post31" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#31</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 28, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">To "KK-Mobile, AL"--a
good vet should be able to make your kitty go out of heat by using the
reliable "Q-Tip" or thermometer method. If your vet is a young one,
he may not know about this. Professional cat breeders do this all the time to
bring their cats out of heat. The method is best left up to the experienced
as you can hurt the kitty if you go too deep. Check with your vet or try
another. Also, maybe get a second opinion on having your cat spayed with the
hernia problem.<br />
The good thing is that the days are getting shorter--the less daylight, the
less a cat will go into heat.<br />
<br />
Also, it is NOT good for a kitty to constantly be in and out of heat and NOT
be bred. You are taking a risk either way you go by letting the kitty go in
and out of heat and not bred or by not choosing the spay. I myself would get
a 2nd opinion on the spay.<br />
<br />
As for vets not knowing about FeralStat--that is understandable, BUT they
should know about megestrol acetate as well as "OvaBan"--especially
if they are "old school vets".<br />
<br />
Again, the main ingredient in FeralStat is just megestrol acetate. The other
ingredient was powdered milk/lactose for taste purposes only.<br />
<br />
Professional cat breeders have been using megestrol acetate for years to
control heats. Check your yellow pages for cat fancy breeders and see if they
have insight on a vet that can prescribe megestrol acetate in your area. Be
sure and check out other online forums devoted to show cats and cat fancy
sites. These breeders are indeed getting megestrol acetate/OvaBan from some
vet somewhere...<br />
<br />
Luckily I have some FeralStat left, plus the non-estrus period is coming up
for all of us.<br />
<br />
I just wish we could find out SOMEONE we can talk to on getting more
FeralStat.<br />
<br />
I'm still looking for alternative source and possibly making it up ourselves.
I'll keep posting what I find...you all do the same....<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Bonnie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/connersville-in"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Connersville, IN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post32" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#32</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 29, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I too am upset that I can no
longer get fetalstat. No kittens and healthy cats. Hope it`s available SOON!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/kkdaniels" title="See KKDaniels's profile"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.5pt;">KKDaniels</span></b></a><b><span style="font-family: "times new roman" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<a href="http://www.topix.com/member/profile/kkdaniels"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt; text-decoration: none;"><!--[if gte vml 1]><v:shape id="Picture_x0020_90"
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/montrose-al"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Montrose, AL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post33" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#33</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 29, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
<div class="MsoNormal" style="background: #F7F7F7; line-height: 9.1pt; text-align: justify;">
<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">To "KK-Mobile,
AL"--a good vet should be able to make your kitty go out of heat by
using the reliable "Q-Tip" or thermometer method. If your vet is a
young one, he may not know about this. Professional cat breeders do this all
the time to bring their cats out of heat. The method is best left up to the
experienced as you can hurt the kitty if you go too deep. Check with your vet
or try another. Also, maybe get a second opinion on having your cat spayed
with the hernia problem.<br />
The good thing is that the days are getting shorter--the less daylight, the
less a cat will go into heat.<br />
Also, it is NOT good for a kitty to constantly be in and out of heat and NOT
be bred. You are taking a risk either way you go by letting the kitty go in
and out of heat and not bred or by not choosing the spay. I myself would get a
2nd opinion on the spay.<br />
As for vets not knowing about FeralStat--that is understandable, BUT they
should know about megestrol acetate as well as "OvaBan"--especially
if they are "old school vets".<br />
Again, the main ingredient in FeralStat is just megestrol acetate. The other
ingredient was powdered milk/lactose for taste purposes only.<br />
Professional cat breeders have been using megestrol acetate for years to
control heats. Check your yellow pages for cat fancy breeders and see if they
have insight on a vet that can prescribe megestrol acetate in your area. Be
sure and check out other online forums devoted to show cats and cat fancy
sites. These breeders are indeed getting megestrol acetate/OvaBan from some
vet somewhere...<br />
Luckily I have some FeralStat left, plus the non-estrus period is coming up
for all of us.<br />
I just wish we could find out SOMEONE we can talk to on getting more
FeralStat.<br />
I'm still looking for alternative source and possibly making it up ourselves.
I'll keep posting what I find...you all do the same....<br />
James<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi, James.<br />
<br />
Let me first say that I've had two opinions already - well, three if I
include another vet at the same hospital as the last one I went to last week.
The first vet said absolutely not, no way, and I would be hard pressed to find
anyone to spay her at all. This new office tells me he would only suggest
doing it while going in for the hernia surgery - if everything is going good,
then he would go ahead and spay her then. See, my problem is that I can't get
her spayed without having the surgery first. And if I have the surgery, I'm
taking a huge risk of losing her. The new vet tells me that many cats live
long lives, as an inside kitty, with Emma's condition and we should keep a
close eye out and take it as it comes for now. So it's darned if I and darned
if I don't. I've never been put in this situation before, and it's just
killing me. I don't want to lose her, and I want to give her every chance at
a long and happy life. What would you do?<br />
<br />
The first vet I took her to said to use the very end of a pencil eraser and
just gently tap the end of it to her back side and sometimes it will fool
them into thinking they've done the deed. The second vet used the Q-tip
method, and neither one of them worked! Woudln't you know it... no fooling
this one. So that's a concern of mine too, that it hasn't worked yet and what
will I do without the FeralStat!<br />
<br />
I am to take her back in a couple weeks for shots, and I'll ask him about the
ingredients and see if he has any idea where I may can get it. In the mean
time, I'll do some research to see if I can find some local breeders in the
area. I appreciate your suggestion on that.<br />
<br />
Yes, please let us know what you find out on the megestrol acetate. If I find
anything out, I'll be sure and post back as well.<br />
<br />
By the way, no one from FeralStat has returned by call yet. Why am I not
surprised! Oh, I wish we could find something out.<br />
<br />
Thanks again, James.:-)<br />
<br />
KK<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
</td>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post34" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#34</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 6, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Wow...you are in between a rock
& a hard place with your kitty...I feel for you! I just with a local vet
and they can get a 100 count bottle of OvaBan for about $25.00 in
tablets.....considerably cheaper than FeralStat! The OvaBan tablets main
ingredient is megestrol acetate--same as FeralStat...<br />
<br />
Many show cat breeders use OvaBan to control heat in their kitties.<br />
<br />
KK, I've never heard of tapping a pencil eraser on back of a cat, but I have
heard of acupressure to bring a kitty out of heat...I ofund this on Net:<br />
<br />
Acupressure To Bring<br />
Your Female Out Of Season<br />
<br />
Acupressure is the simple application of pressure on specific points on the
body. These "pressure points" are the same as those incorporated in
the practice of acupuncture. Acupressure differs from acupuncture in that it
does not involve the use of needles.<br />
<br />
The Technique<br />
<br />
Acupressure can be used to bring a female out of heat. The technique is easy to
learn and apply.<br />
<br />
* Scruff the queen firmly on the back of the neck with one hand. Most queens
in season will then assume the breeding position.<br />
* With your other hand, stroke down her back and tap lightly along her
flanks, mimicking the actions of a breeding male.<br />
* Tickle her at the base of her tail until she is treading and obviously
receptive.<br />
* With your thumb and forefinger, feel for the depression each side side of
the tail. They will be between the base of the tail and the bony protrusions
or knob on each side of the tail.<br />
* At the same time, press firmly with your thumb and index finger in each of
the two depressions.<br />
* The pressure should be firm enough to make the queen voice the
characteristic growl of breeding.<br />
* Press for at least 10 seconds, then release.<br />
* If you have been successful, the queen will growl, scream and when you let
her go she will roll as if mated.<br />
* Repeat this 2 or 3 times in the first hour and then another 4 or 5 times
over the next 24 hours.<br />
* Repeat twice a day for 3 days.<br />
<br />
Success Rate<br />
<br />
Acupressure for a cycling female works well for some cats and not at all for
others.<br />
<br />
If it is going to work, the female will be out of season in 2 or 3 days and
will not cycle again for 6-8 weeks.<br />
<br />
Risks<br />
<br />
Don't forget that the hormonal changes caused by ovulation can increase the
risk of fertility problems or of the queen developing pyometra. Individual
queens vary in how susceptible they are to these hormonal changes and the
effects may be cumulative, so be aware that any technique used to delay
breeding comes with risks.<br />
<br />
==========<br />
<br />
As for the Q-tip method tried by your vet, you did good by letting your vet
try it as Q-tip method is invasive and penetrative and best left up to
experts.<br />
<br />
Check with your vet to see if he/she can get you a scrip to OvaBan. Some vets
are not familiar with use of Ovaban and dosage of it, etc....post back if you
need me to send you dosage info.<br />
<br />
Good luck with your kitty...I feel for you and your baby...<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Raini<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Thunder Bay, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post35" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#35</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 11, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Yes, I too am in ire straits,
after giving Feralstat to a feral colony of 24 cats, I had results. The
colony is now only 14. This was successful within the year, since January.
How do I reach Dr. Heller or another compassionate associate. I cannot forsee
the colony expanding again with winter setting in. There has been no new
litters. Could some individual vet or association please help.<br />
Email me at mononenraini@hotmail.com.<br />
Thank you.<o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/kkdaniels" title="See KKDaniels's profile"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.5pt;">KKDaniels</span></b></a><b><span style="font-family: "times new roman" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Sep 11<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/montrose-al"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Montrose, AL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post36" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#36</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 11, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Wow...you are in
between a rock & a hard place with your kitty...I feel for you! I just
with a local vet and they can get a 100 count bottle of OvaBan for about
$25.00 in tablets.....considerably cheaper than FeralStat! The OvaBan tablets
main ingredient is megestrol acetate--same as FeralStat...<br />
Check with your vet to see if he/she can get you a scrip to OvaBan. Some vets
are not familiar with use of Ovaban and dosage of it, etc....post back if you
need me to send you dosage info.<br />
Good luck with your kitty...I feel for you and your baby...<br />
James<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James, yes, I really am in a bad
place with Emma. I hope and pray that her vet will know of OvaBan and can get
some for me. I would love to know the dosage for keeping her out of heat,
though, as I need to save as much time as possible, just in case he's not
aware of it. So thank you so much. And thank you for posting the acupuncture
technique. If all else fails, I may have to try it, but I don't look forward
to it at all. I'm not good at this kind of thing and I fear of hurting her
for lack of confidence. So nice of you to find it for me!!!<br />
<br />
Still no news from FeralStat. You would think somebody would make some sort
of statement out here in their world of supporters, wouldn't you? I can't
wrap my head around why there's no word at all knowing there's tons of us who
are in need for our little fur babies! A big disappointment indeed.<br />
<br />
But if you can forward the dosage info for me, that'd be great. I'll post
back when I visit her vet again, probably next week sometime. Thanks again so
much for your help and concern!<br />
<br />
KK<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Judy<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/austin"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Austin, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post37" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#37</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 14, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">There isn't anything I can add
that hasn't already been said. I am devastated at the thought of going back
to 30 new kittens twice a year. I've used FeralStat going on 3 years...and
not one kitten. It has given me time to TNR, but new cats keep coming into
the colony and FeralStat was my savior. I am having a hard time figuring out
how something that works so well can no longer be provided. Tell me more
about OvaBan. Is it a pill or a sprinkle on? As you know pills won't work
with ferals. I tried contacting my vet, but they were aghast that I would use
Feralstat. I must find something to help control my colony. I lose some to
coyotes and/or fox, but otherwise very healthy! Please Feralstat...we need
you!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">dmkakers<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/poway-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Poway, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post38" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#38</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 14, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi, I live in California. My Mom
age 81, has been using Feralstat for the last 6 mo. Two weeks ago she started
calling her pharmacy to get the next batch of Feralstat. Well the pharmacy
does not answer her calls and the Vet. she used to get the prescribtion to
get the Feralstat is not answering either. She needs to reup asap. Can you
give me the Vet you are using and the pharmacy number? She can then have it
shipped to her. I have also been looking on the internet, and your the first
person replying on the sights thats in the year 2011. Thats why I'm trying to
get a hold of you. Can you help us please? Hope to hear from you soon. Here
is my e-mail address. dmkakers@hotmail.com In case I lose you on this sight.
Thank You Dorothy McDonald><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">leslie leavitt wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">I have used FeralStat on a feral colony for about 2 and a half
years. Have not had one kitten born in that time. The cats appear to be
healthy. I will continue to use it despite negative comments. The life of a
feral is hard at best. They are already subject to all kinds of illnesses and
diseases and while the thought of adding to their troubles with FeralStat is
not my intention I will continue to use it. Preventing feral kittens from
being born is my goal at this time. I have tried many times to trap these
cats but they are very trap wary.<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post39" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#39</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 14, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">OvaBan comes in a pill form. A
small portion of the pill is usually crushed up & placed in food.
Generally, cat breeders use 2.5 mg ONCE A WEEK. Some breeders use as little
as 1.25 mg every 3 weeks....others have found that OvaBan can be dosed a
little farther apart in the winter than in the summer.<br />
<br />
My vet can get me 100 OvaBan tablets for about $25.00--this is a LOT cheaper
than FeralStat. You are only using a portion of ONE single OvaBan tablet per
dosage every week or so as stated above.<br />
<br />
Ladies, you are going to have to use GOOGLE to research OvaBan and ASK YOUR
VET for a prescription. You can probably forget FeralStat for the time
being.<br />
<br />
THE ONLY ALTERNATIVE TO FERALSTAT IS OVABAN! You will have to find a vet that
knows about OvaBan and will prescribe it to you--plain and simple.<br />
<br />
As I have already stated, OvaBan is used by professional show cat breeders in
the cat fancy world to control heats in their cats. For those of you in large
cities, look for cat fancy/show breeders--get your phone books out & call
your vets to see if they will prescribe you OvaBan.<br />
<br />
As I said, this is the ONLY alternative to FeralStat for the time being until
FeralStat decides to come back--which I highly doubt.<br />
<br />
Check with "CAT ONLY" veterinarians if need be for OvaBan--most all
of your current "all purpose horse,cow, dog,cat vets" are probably
NOT going to know about OvaBan.<br />
<br />
You have the whole world at your fingertips as far as information and
research is concerned--use GOOGLE. Google is your friend..google
"OvaBan" and read, read, read, read....<br />
<br />
Hope this helps...<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post40" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#40</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 14, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Also, check out fancy/show cat
forums for OvaBan usage. If you have exotic cat breeders in your town, call
them up and ask them if they perhaps have a prescription to OvaBan and maybe
they can "give" you a few pills or maybe they can turn you on to
the veterinarian that will prescribe it for you. OvaBan is not just used for
heat control--it is given by many vets for behavioral problems such as
spraying/marking...<br />
<br />
Look in your phone books and start calling all vets--sooner or later you will
find a vet that will prescribe OvaBan.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p2"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post43" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#43</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ok Ladies, I may have found a
solution to our problem! After 100's of hours researching & using Google,
I've found a Non-profit Foundation that prescribes OvaBan/MegAce. MegAce is
human equivalent of megestrol acetate.<br />
<br />
It seems as if I've found the same formula as FeralStat itself!<br />
<br />
I KNEW I could find a DIY for us to make our own FeralStat if I kept digging.<br />
<br />
The website is:(scroll to bottom half of page)<br />
</span><a href="http://www.fairchildcat.org/rich_text_1.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.fairchildcat.org/rich_text_1.html</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
Not sure if they mail order--if any of you call them up, please post your
results here for all of us to share.<br />
<br />
Here is the formula they list. I hope I have helped you all out...now that we
seem to have an alternative to FeralStat, it should be easy to get
MegAce/OvaBan from our vets & mix our own & save $.<br />
<br />
Here's the info:<br />
<br />
Ovaban is utilized as an oral contraceptive to reduce the number of litters
born into a colony<br />
while the cats are being humane trapped and neutered. The dosages indicated
below are low enough to be safe but effective based on previous studies. We
have had great success in preventing HUNDREDS of Pregnancies in the past 10
years, thus reducing the unwanted cat overpopulation BY MILLIONS!<br />
<br />
NEVER give more medication than is directed. Human Megace (40 mg/ml) is diluted
down to 5 mg per ml with distilled water--this suspension is used instead of
crushing the name-brand Ovaban tablets (1 tablet = 1 ml).<br />
<br />
It is very important that you continually evaluate the size of your colony
and insure that you are using the correct dosage and frequency for the size
of your colony.<br />
<br />
<br />
<br />
Total Number of Cats in the Colony - Dosage per colony / Frequency<br />
<br />
< 5 cats .5 ml ONCE a week<br />
5-7 cats 1.0 ml ONCE a week<br />
8-11 cats 1.5 ml ONCE a week<br />
12-15 cats 1.0 ml TWICE A WEEK<br />
16-19 cats 1.5 ml TWICE A WEEK<br />
20-23 cats 1.6 ml TWICE A WEEK<br />
24-27 cats 2.0 ml TWICE A WEEK<br />
28-31 cats 2.2 ml TWICE A WEEK<br />
32-35 cats 2.5 ml TWICE A WEEK<br />
36-39 cats 2.8 ml TWICE A WEEK<br />
40 + cats 3.0 ml TWICE A WEEK<br />
NOTE: For the 3cc syringe each line is 0.1 ml whereas on the 6cc syringe each
line is 0.2 ml<br />
<br />
1) This medication MUST be mixed in CANNED cat food and served on multiple
plates or dishes (NO PAPER). Use one 5.5 oz can of cat food for every 3 cats
in your colony. It is very important to spread it out on as many plates as
possible so the entire colony is being medicated as evenly as possible.<br />
<br />
2)Shake the bottle of medication vigorously as the ovaban settles to the
bottom. It is very important that the ovaban is mixed thoroughly before
dosing to avoid under/overdose.Divide the appropriate dose of medication for
your colony evenly among the plates of food and mix it thoroughly into each
plate of food.<br />
<br />
3)DO NOT DISPENSE IN MILK OR MILK PRODUCTS!<br />
<br />
4)Store medication with bottle tightly capped in a cool, dry place away from
sunlight.<br />
<br />
5)Wash syringe with dish soap and water. Rinse thoroughly. Allow syringe to
air dry on a paper towel.<br />
<br />
6)DO NOT SKIP OR MISS A DOSE!If you were unable to dose the cats on your
scheduled day, do so on the very next day and resume your schedule the
following week. For colonies that require a frequency of 2 x per week, the
dosages MUST be spaced out.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">J STONE<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">AOL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post1" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#1</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 29, 2008</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Birth control pills for animals
encluding a permanate pill to add to street cats food is available and in
usage quite successful in progressine countries, In the USA special intrest
is feeding the fools the crap that more testing and all the
other bull and have been doing this for 50 years because of special
intrest. This must be put into the hands of the people now for real progress
to the age old problem.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">mowgli<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cromwell-ct"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cromwell, CT</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post2" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#2</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 29, 2008</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">thank-you<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">catlady in stl<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Saint Louis, MO<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post3" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#3</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 21, 2009</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Seriously what aother alternatives
are there when you cannot trap the source of the multiple litters of kittens
in a feral colony? I'm sorry these people ACCD feel threatened and from what
I've read are trying to develop their own feline contraceptive, but what
about the average joe like me that feeds and takes care of these strays and
is just beyond done with it?<br />
<br />
Everytime I trap kittens I can't get any help from the rescues in my area, my
friends and neighbors are done they've taken way too many of these kittens. I
am going to have to have faith that the risks of the Feralstat aren't as
great as allowing the non-stop kitten factory to continue.<br />
<br />
I feed all of these ferals out of my own pocket and I take care of them the
best I can but enough is emough. I'll post back to let everyone know if this
product works or not.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Jane in PA<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/southampton-pa"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Southampton, PA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post4" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#4</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Oct 10, 2009</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">In the busy spring and summer
months, one is able to get very little help from the cat rescue groups. I was
told by several friends to try a well-known county group for help with TNR,
since I didn't know where to start, had tons of questions, and didn't know what
was out there to help me.<br />
<br />
I couldn't get anyone to call back. In fact, one of the answering
machine messages said, "If you've called before and have already
left a message, please don't leave another one!" I was distraught, to
say the least!<br />
<br />
I realized I was mostly on my own for learning how to trap and release my
ferals. One trained rescuer (whom I found online), recommended a couple
veterinarians who offer discounts, which was very valuable information
to me.<br />
<br />
I have successfully trapped several cats and kittens now (whew!)- but at one
time was considering birth control, because I had no other choice.<br />
<br />
People who try this method are desperate for a solution,
because there is so little information out there as to what to do. Often it
is seen as an interimsolution. I am worried about some of the
reported side effects, but perhaps it's OK if the product is only used
short-term, until the cat can be caught and safely neutered.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/albuquerque"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Albuquerque, NM</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post5" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#5</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 17, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have used FeralStat on a feral
colony for about 2 and a half years. Have not had one kitten born in that
time. The cats appear to be healthy. I will continue to use it despite
negative comments. The life of a feral is hard at best. They are already
subject to all kinds of illnesses and diseases and while the thought of
adding to their troubles with FeralStat is not my intention I will continue
to use it. Preventing feral kittens from being born is my goal at this time.
I have tried many times to trap these cats but they are very trap wary.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">kcook924<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/brattleboro-vt"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Brattleboro, VT</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post6" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#6</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Did the FeralStat work? I am faced
with the same problem as you.<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">catlady in stl wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Seriously what aother alternatives are there when you cannot
trap the source of the multiple litters of kittens in a feral colony? I'm
sorry these people ACCD feel threatened and from what I've read are trying to
develop their own feline contraceptive, but what about the average joe like
me that feeds and takes care of these strays and is just beyond done with it?<br />
Everytime I trap kittens I can't get any help from the rescues in my area, my
friends and neighbors are done they've taken way too many of these kittens. I
am going to have to have faith that the risks of the Feralstat aren't as
great as allowing the non-stop kitten factory to continue.<br />
I feed all of these ferals out of my own pocket and I take care of them the
best I can but enough is emough. I'll post back to let everyone know if this
product works or not.<o:p></o:p></span></i></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">kcook924<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/brattleboro-vt"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Brattleboro, VT</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post7" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#7</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Did the FeralStat work? I am faced
with the same problem as many out there are.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">kcook924<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/brattleboro-vt"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Brattleboro, VT</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post8" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#8</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Did the FeralStat work?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/santa-fe-nm"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Santa Fe, NM</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post9" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#9</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 31, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">For whoever judged me clueless, be
sure and let me know when you come up with a better alternative. Since you
are so smart, I;m sure it will be soon<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Bajapamella<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post10" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#10</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 5, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I just tried to contact feralstat
to order a prescription for my feral colony. I got a message that they are no
longer renewing nor filling orders and to call back on August 15th for an
update. Does anyone know what is going on or soemone else I can contact for
birth control for my cat colony. I'm desperate to stop them from reproducing.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Gail from Hilltop Humane<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/abington-ma"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Abington, MA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post11" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#11</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 6, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Search the info on the Web about
feralstat and you can find the name of thegeneric drug. If you have a vet
that you work with frequently, you may be able to get a prescription for
that. It should be a lot cheaper anyway. I'm sorry, I just moved and I can't
find the pages I printed off previously with the name. The people who make a
fuss about possible side effects of the drug are ignoring the
"side effects" of repeated pregnancies on these poor feral moms.
I'm talking with the President of our organization about doing a trial. We've
been swamped with kittens this year like everyone else and donations are
down. If you get the generic, let us know how it works.<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Bajapamella wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">I just tried to contact feralstat to order a prescription for
my feral colony. I got a message that they are no longer renewing nor filling
orders and to call back on August 15th for an update. Does anyone know what
is going on or soemone else I can contact for birth control for my cat
colony. I'm desperate to stop them from reproducing.<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Bea Sturges<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">West Bloomfield, MI<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post12" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#12</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 19, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I called today for a refill of
feralstat and couldn't get an answer today. Does anybody know what is going
on?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Bea Sturges<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">West Bloomfield, MI<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post13" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#13</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 19, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Feralstat works great. But why
can't I get a refill now?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Bajapamella<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post14" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#14</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 19, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Bea Sturges wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Feralstat works
great. But why can't I get a refill now?<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">. I keep trying feral stat but no
answer. Please let us know if you find another source or are able to refill.
Ive been trying for over a month and am so disappointed.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Deborah<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/chisholm-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Chisholm, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post15" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#15</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 27, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">kcook924 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Did the FeralStat
work? I am faced with the same problem as many out there are.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I used feralstat for the last
couple of years. I think it works great. No new kittens & the cats look
healthy. But am having a hard time getting it this time. I have one pack of
feralstat left, but when I called to get more a recording told me that the
office was closed & that they were not taking any orders for refills or
new prescriptions. And to try back in a couple of weeks. but I need more now.
Don't know what to do now.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ginger<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post16" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#16</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 31, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have used feral stat for 2
years. No new kittens and the cats look healthy. I can't take care of any
more. I am getting the same message. Now no answer. I'm desperate and need it
now. What is going on? Please let me know if you find a place to get it.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">julie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tempe-az"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tempe, AZ</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post17" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#17</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 7, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">It's Sept 8, 2011. I have one week
of Feral Stat left and I have 60 cats on it. Can you imagine what can happen
with that many once it is used up? I must find out what's going on, so is
there any updates?<br />
<br />
Also, when folks talk about side effects....read carefully, there are
none to speak of. It states these things can happen in LARGE doses. Also, how
does one supposed "expert" really know. Heck, vet
"experts" do not even know about the miracle cure apple cider
vinegar for cats and even newborn kittens.<br />
<br />
I have used Feral Stat since 2009 with no problems and no kittens.
jaws6418@gmail.com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ginger<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post18" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#18</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 8, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Gail from Hilltop Humane wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Search the info on
the Web about feralstat and you can find the name of the generic drug. If you
have a vet that you work with frequently, you may be able to get a
prescription for that. It should be a lot cheaper anyway. I'm sorry, I just
moved and I can't find the pages I printed off previously with the name. The
people who make a fuss about possible side effects of the drug are ignoring
the "side effects" of repeated pregnancies on these poor feral
moms. I'm talking with the President of our organization about doing a trial.
We've been swamped with kittens this year like everyone else and donations
are down. If you get the generic, let us know how it works.<br />
<quoted text><o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Did you happen to remember the
name of the generic drug. I don't know if I could find a vet to get it from.
They all say they have never heard of Feralstat.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post19" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#19</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 11, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have been using feral stat for
almost a year now - I have about a 2 months supply left so I must have been
able to renew just before they stopped refilling prescriptions. This is
devastating news! The cats in my colony are all healthy - and no kittens. I
am doing tnr all on my own and was down to one female last summer who I was
having difficulty catchin - and she had 6 kittens! So now I am back up. I
only have access to a spay neuter clinic once a month and since the only
place I can allow the cat to recuperate is a garage, that means that the
middle of winter and middle of summer are out because of the extreme
temperatures. Feralstat has been a life safer! There must be something we can
do to get this product back into availability. The possible side effects from
this drug are no where near the definite side effects of too many kittens
dying horrible deaths through starvation, predation (11 died here the year
before - 5 by drowning in a flooded stream; 4 torn apart by some wild animal;
1 hit by a car; and 1 killed by a wild animal, and the nuisance problems
caused with neighbours from fighting and spraying. That has all stopped while
they are on feralstat. I have rescued as many as I can, found homes for as
many as I can and with feralstat finally had a chance to get caught up on the
neutering of the ones remaining. I have found none of the feral cat
organizations willing to give me any sort of practical hands on help - just
refer me to their literature. And if they are responsible for feralstat being
off the market that is another black mark to their discredit. It seems like
they have forgotten what it is like to be the lone caregiver on the ground dealing
with the practical day to day realities. I can't believe their hypocrisy! I
hope, hope, hope that the vet who was willing to actually do something to
help will see this and return to practice. I'm no longer making a donation to
Alley Cat Allies since they seem to be one of the most vocal against this
use. They have obviously lost touch with reality - no practical help, no
resources for the little guy and now removing one of the only resources we
have to give us a chance to gain control of our colonies.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post20" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#20</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 11, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">megestrol acetate - that is the
name of the product in feralstat.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #5b5b5b; font-family: "roboto" , "serif"; font-size: 16.5pt;">Tell
me when this thread is updated:<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/alerts/subscribe-thread?forum=med/med&threadid=O5BM504OU9T4PASQ"><span style="background: white; border: solid #dddddd 1.0pt; color: #336699; font-family: "roboto" , "serif"; font-size: 13.0pt; padding: 0in;">Subscribe Now</span></a><span style="color: #5b5b5b; font-family: "roboto" , "serif"; font-size: 16.5pt;"> </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ"><span style="background: white; border: solid #dddddd 1.0pt; color: #336699; font-family: "roboto" , "serif"; font-size: 12.0pt; padding: 0in; text-decoration: none;"> </span><span style="background: white; border: solid #dddddd 1.0pt; color: #336699; font-family: "roboto" , "serif"; font-size: 12.0pt; padding: 0in;">Add to my Tracker</span></a><span style="color: #5b5b5b; font-family: "roboto" , "serif"; font-size: 16.5pt;"> <o:p></o:p></span></div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-31425573448152896522018-07-01T20:34:00.000-07:002018-07-20T14:18:44.445-07:00Topix thread 06152015 posts 84 to 131<table border="0" cellpadding="0" class="MsoNormalTable" style="mso-cellspacing: 1.5pt; mso-yfti-tbllook: 1184; width: 640px;">
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post112" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#112</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ginger: I have created a
disposable email address that you can email me at and ask me for the flea and
antibiotic information.<br />
<br />
This will protect you from having to publicly post YOUR email address here
for everyone to see just so I can reply to your request for info.<br />
<br />
Contact me at this email address:<br />
<br />
ftaboxer AT yahoo DOT com<br />
<br />
I will send you the info once you have emailed me.<br />
<br />
The email address I posted above will be disposable--once it gets junked up
with spam from trolls & robots it will be disposed of and not answered by
me, so in the future, if in a few days or so and others want the info, I may
have to create another one.<br />
<br />
For now, use the email addy I posted--we'll get a few days use out of it
before it gets spammed.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p6" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p6" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p6"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Jack<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/sunderland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Sunderland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post113" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#113</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">So, is there or is there not
contraceptives for cats now on the market? Had great success with Feralstat<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p6" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p6" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p6"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post114" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#114</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 2, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I prepared a package of
information about both my colony and ferastat, and included the link to
this site along with a number of posts, and presented it to my vet with
my request for a prescription. She read over everything, and then we had a good
discussion about the situation and options. She said that Ovaban is not much
favoured by vets due to its potential side effects and she does not
use it except as a means of last resort when the life or well-being of the
animal is already at risk and the side effects are considered a
reasonable risk under the circumstances. She said that she has never heard of
it being used in such small doses before, though, and agreed that this could
make a significant difference in the potential of side effects.
She also agreed that the known health threats and risks to both feral mothers
and their kittens from the female having multiple litters of
kittens in the wild every year, and the problem of trying to keep on top of
the numbers with a spay neuter program but without access to deep pockets and
available resources were far greater than the potential for a risks from
possible side effects from the ovaban. She has written me a
prescription. I will be keeping her informed about the health of the colony,
as she is interested in how this works out as she had never heard about
feralstat before. I am so grateful I have both a compassionate and sensible
vet! Thank you, James, for providing the information about the dosages. The
100 capsule bottle will definitely keep us going for a long time.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post115" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#115</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 3, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn, I am glad you have a vet
with common sense. Once a sensible person weighs the risk of NO BIRTH CONTROL
for a colony vs. the minisculeside effects of megestrol acetate, then
most vets will prescribe the medicine. If you watch the "DOT
COM" TV ads for HUMAN medicines advertised during the afternoon
hours and listen to the side effects, then one would be scared to take
the medicines, but you can see big Pharma is making billion$ off human
drugs, even with the side effects.<br />
<br />
Once a vet is EDUCATED about megestrol acetate then they usually come to their
senses. It's just that the "educating" part of MA usually has to be
done by people like us.<br />
<br />
I'm glad it worked out for you and by all of us working together here, maybe
we can make a difference in the feral cat population.<br />
<br />
I am curious...what did you have to pay for a 100 count bottle?<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post116" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#116</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 3, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi James,<br />
<br />
I paid $26.20 which is definitely a better price than the feralstat! It's a
good thing I already had a pill splitter and a pill crusher as it was
interesting getting a dosage of 7.5 gm for my colony that currently numbers
11. One quarter pill and then 1/8th pill. It is the same dosage I was getting
with the feral stat but you can really see where the added filler provided
the bulk of the package.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post117" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#117</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 4, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James ..can you please email me
peronally & let me know how you kpow of the dosage as 20mg & also how
you know that lactose powder isnt necessary...i'm on my last few cats dosage
& not sure what i will do..thanks for your knowledge on this subject...<br />
dawnie129@yahoo.com<br />
anyone else with any more info on this topic please contact me as well<br />
dawn<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ginger<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post118" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#118</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 4, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Has anyone found a place to get
the feral stat? Every day is getting longer which means spring is on its way.
What to do? I have not found a vet to work with. email gweimer@atlanticbb.net<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">janeyjan<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post119" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#119</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 4, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I was serching the net for any an
all info on the drug, FeralStat, and came accross this forum.<br />
After calling, the company and ofcourse not getting anywhere, I went online
an found a place in California. It's called<br />
catafratsRX online pharmacy.<br />
Dr. Bruce Isenberg, is a licensed pharmacist, who will prescribe and sell.
Megestrol acetate. 20mg.<br />
You must,however, give the name of your local vet , which he will contact
before mailing out the pills. Mine came in less than 10 days.<br />
I paid 105.00 for 160 pills.(16 cats, and feed for 10 months)<br />
After reading the post from Kathryn, from GA.<br />
where she was able to get 100 pills (20 mg each) for 26.20 , I was a bit
upset to have to pay , so much more. On the other hand, a hundred dollar bill
is much much cheaper than all those unwanted kittens, plus the food to feed
them<br />
I have 35 farm cats, 10 of which have been spayed. but feed only 16 females
the MA ,<br />
Each friday is their "day". Put the medicine, in a tablespoon
of canned cat foodand place the plate, infront of them and
wah-la.. they are taken care of for a week!!<br />
anyone who might want to chat with me, may do so, by emailing me at
jhowardson@itctel.com<br />
jane<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post120" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#120</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 4, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">For those concerned about the
dosage of liquid MegAce or Megestrol Acetate (Ovaban) tablets, go back and
read this link by Dr. Fry at Fairchild:<br />
</span><a href="http://www.fairchildcat.org/rich_text_1.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.fairchildcat.org/rich_text_1.html</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
Some of us cannot get liquid MegAce, thus we have to use Megestrol Acetate
(MA) TABLETS, usually in 20 mg each tablets. Thus we have to convert MA
(Ovaban) tablets, 20 mg each, into a liquid suspension as it is very hard to
break up the tablets into the miniscule amounts necessary for proper dosages.
Here's how:<br />
<br />
Converting OvaBan/MA (20 mg each) Tablets Into Liquid Suspension<br />
<br />
Many users of OvaBan tablets are having a hard time finding the 5 mg OvaBan
tablets as outlined in the dosage charts. It seems that the more common
OvaBan/MA tablets are actually 20 mg per tablet rather than 5 mg per tablet.
If you are a feral colony care giver, you can see that it would be quite
difficult to divide a 20 mg tablet into 1 & 2/3 tablets for a colony of
20-23 cats as outlined in the OvaBan tablet (5 mg each tablet) dosage chart.
If your vet's supplier cannot find the 5 mg OvaBan tablets and can only find
the 20 mg tablets, then it is best to make up an oral suspension of OvaBan/MA
by mixing the 20 mg each OvaBan tablets with distilled water. Once you have
mixed the OvaBan tablets with distilled water then you can refer to the
chart at the link for dosingof liquid MegAce.<br />
<br />
Use a pill crusher. Crush the pills thoroughly. Here are the correct mixing
ratios for converting tablets into liquid suspension:<br />
Remember you have OvaBan/MA in 20 mg tablets-1 tablet at 20 mg per tablet is
equivalent to 4 OvaBan tablets at 5 mg per tablet. Follow the charts in the
link above for liquid MegAce which mix at 7 parts distilled water to 1 part
liquid MegAce. The liquid MegAce is available at 40 mg per ml. If you
actually buy the liquid MegAce to use, then 1 ml of the liquid MegAce would
be diluted into 7 ml of distilled water.<br />
<br />
However, since we are using 20 mg OvaBan tablets rather than liquid MegAce
then you will need to crush 2 of the 20 mg each tablets (40 mg total) and
then dissolve them into 8 ml of distilled water. Once dissolved, you now will
have 8 ml of liquid MegAce with 5 mg of megestrol acetate in each ml.(40 mg
divided by 8 ml = 5 mg per ml.) This is now the same strength as if you had
bought a bottle of liquid MegAce and diluted 1 ml of it into 7 ml of
distilled water.<br />
<br />
All we have done is we have taken 2 OvaBan tablets at 20 mg per tablet,
crushed thoroughly, and mixed with 8 ml of distilled water. It would be very
hard to divide and cut up the proper dosage (1&2/3 of the 5 mg tablets)
for a colony of 20-23 cats if you only had the 20 mg OvaBan tablets.<br />
However, since we have converted 2 of the 20 mg each OvaBan tablets into a
liquid, it is very easy to now dose the colony at 1.6 ml of the liquid MegAce
we just made, which is the amount we need for a colony of 20-23 ferals as
shown on the liquid MegAce dosage chart earlier.<br />
<br />
Now, simply use a needleless syringe to draw up 1.6 ml from the 8 ml
suspension we just made. You may want to mix up larger quantities of the 20
mg OvaBan tablets to make future dosings easier. Store the newly made liquid
OvaBan as you normally would liquid MegAce.<br />
<br />
Also, the tablets your vet prescribes you may not be actually branded as
OvaBan. I have seen bottles labeled as just "Megestrol Acetate"
rather than have the brand name of OvaBan on them. These are the same as the
brand name OvaBan and the most common strength of these will be 20 mg
tablets.<br />
<br />
I cannot stress enough that overdosing of MA/OvaBan is NOT advised. You MUST
follow the dosages as outlined above.<br />
<br />
And again, lactose powder like in the original FeralStat is strictly for
taste purposes to mask the bad taste of the MA/OvaBan. It is NOT needed for
contraceptive purposes.<br />
<br />
Re-read the link at Fairchild again & you'll see that they do NOT use
lactose for their colonies.<br />
<br />
</span><a href="http://www.fairchildcat.org/rich_text_1.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.fairchildcat.org/rich_text_1.html</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post121" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#121</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 4, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Jane:$100.00 for 160 pills is not
bad for MA considering it is so difficult to find a vet that is educated
enough on the use of the drug.<br />
<br />
I appreciate you posting the info for your source. I will keep him in mind in
case my vet retires.<br />
<br />
I would gladly pay that for 160 pills if I had no other choice--it is still
MUCH cheaper than FeralStat.<br />
<br />
If you convert the tablets into liquid suspension, assuming they are 20 mg
tablets each, you will sure get your money's worth. Since you are only
feeding 16 females the MA, that works out to 1.5 ml of liquid suspension
TWICE a week--so you see those 160 pills will last a long time. Since 2 pills
make up an 8 ml suspension in distilled water, you see you will get about 2
1/2 weeks dosing out of those 2 pills at 1.5 ml twice a week in a liquid
suspension. Again, that is assuming that your pills are 20 mg each tablet.<br />
<br />
Thanks again for posting that info--I'm filing it for future use if
necessary.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post122" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#122</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 5, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi James..i'm still a little
comfused on the dosage..feralstat i was giving each cat 1/8th of a teaspoon
in theirt wet food..can you please be more specific as to how to mix the
megestrol acetate to liquify it & then divide it..is there an easier way
to just divide the pill & ground up & add to the wet food?..Thanks
everyone for all your help...I have 20 cats ..8 females & have been using
feralstat for the passed 2 yrs...this week is my last batch & i have 4
cats that still need it...have to find a vet to help or will contact who Jane
mentioned..unfortunately if the Dr. calls my vet i think they will nix
it...last time i mentioned they were on Feralstat she went ito the whole
thngs about side effects..i think having tons of unwanted kittens is worse...THANKS
AGAIN!<br />
dawnie129@yahoo.com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post123" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#123</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 5, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James..1 moe thing..why do you
have to give it to the cats twice a week when Feralstat was only one a week?<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post124" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#124</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 5, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Jane..i went to that online
suggestion but there doesnt seem to be a phone # for them...only an address
when you go to contact them..would you have their #..THANKS...sorry for all
my posts but as you can probably see i'm getting a bit desperate here<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post125" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#125</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 5, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Dawn, look back at the link to
Fairchild Cat and you will see the dosage link that Dr. Fry at Fairchild
lists. Her dosage frequency chart lists the dosage based on number in colony
and you will see she lists the frequency. You should be able to email her
with any questions about their tried & true method of using MA to control
estrus.<br />
<br />
My guess is that perhaps Dr. Catalbiano, inventor of FeralStat Inc. was using
a much higher strength of MA in his Feralstat formula. Feralstat was
secretive about their ingredients. I'd suggest emailing Fairchild and asking
them for guidance on dosage if you are not sure of the amounts for your
colony. Fairchild has been using this method of contraception for over 10
years.<br />
<br />
As for clearer instructs on liquefying MA in a liquid suspension...not sure
what you mean here. In a nutshell, you are taking TWO MA/Ovaban tablets of 20
mg strength each, crushing them thoroughly and mix/dissolve them with 8 ml of
distilled water. Shake thoroughly and you now have 8ml of a LIQUID that is
equivalent to the liquid brand of MA known as "MegAce" as outlined
in Fairchild's link that I posted above. Your mixed solution is now 8ml of
liquid suspension, 40 mg strength with 5 mg of MA in each ml.<br />
<br />
Go to the link, scroll down to the bottom of the page and you will see
Fairchild's dosage chart for the use of liquid MegAce (40 mg) diluted down to
5 mg of MA in a single ML. Thus 8 ml of liquid MegAce is 40 mg strength total
as 8 ml x 5 mg per ml = 40mg.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post126" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#126</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 5, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">thanks James..will do..all i know
is i was giving each cat individualy 1/8th teaspoon in their food once a
week..was trying to not have to mix just divide the pill..this forum is the
best i have found..at least here people care about stopping the spread of
endless kittens..hopefully i can get the megestrol acetate real soon!<br />
thanks again!<o:p></o:p></span></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post127" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#127</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 5, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Actually, by using a liquid measure
of the MA in a liquid suspension, you can better control the true amount of
the dosage than you can by using a pill cutter to divide up the pills into
small amounts. Accuracy in dosage is critical here and it is much easier to
measure ML in an eyedropper or needle-less syringe than for example trying to
cut up a pill in to 1 2/3 pieces.<br />
<br />
I sincerely hope you can find a vet that will give you an RX for the
medicine...just remember EDUCATION of the vet on the subject/use of MA is
probably a crucial factor as most vets just simply do not know of the use of
MA for our purposes.<br />
<br />
Good luck!<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/huntingtown-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Huntingtown, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post128" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#128</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have contacted my local Friends
of Felines and they will take care of spay and neuter for a donation. Also
test cats, give shots and micro chip them. All I have to do is promise to
take them back and feed them.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Betty McIntyre<o:p></o:p></span></b></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">We are fortunate enough that our
vet ordered megestrol acetate for us and assures us it will have the same
results as feralstat. I am so grateful for this and hope you all will be so
fortunate. Thanks for all the good information.<o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Betty..can you tell me how you're
using it..as i mentioned above..i have 8 females & was giving each cat
individually 1/8th teaspoon mixed in their dry food..THANKS everyone for all
your help..just knowing there are some vets willing to prescibe megestrol
acetate for the control of kittens gives me some hope i'll be able to obtain
it<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/clark-sd"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Clark, SD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post131" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#131</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 8, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi everyone,<br />
I am curious, about those of you, who are still feeding the birth control,
what ever you use..this time of the year??<br />
I only feed from Jan, thru mid Nov.? ofcourse I do live in the upper midwest
and the cold, does affect the breeding season for cats,(or so I am told.) I
have lived here for 40 years and NEVER had kittens in the
winter.ever..........<br />
I guess my point to this post is, you wouldnt need so much , if you only fed
for 10 months of the year.<br />
I also, called back to the place in california, and asked the pharamcists, if
the dosage of 1/4 of a 20 mg. ovaban tab. would be to much for one
cat...since I just put it in a small amount of canned cat food. his reply was
,<br />
absolutely not.!!!! then he thanked me for taking care of all the cats that I
have..<br />
Jane<br />
p.s. I wonder if anyone would like the telephone number to that Catsafrat RX
online pharmacy, where I purchased my ovaban?<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Gail from Hilltop Humane<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/abington-ma"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Abington, MA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post84" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#84</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 19, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">The kittens should do fine with
time but the older ferals take a lot of patience and some will never be
really domesticated. I trapped one where I lived over 3 years ago (which is
how I got involved with Hilltop Humane Society, a cat rescue organization and
shelter in Randolph, MA). It was supposed to have been TNR
(trap-neuter-return) but I had trouble following through with the
"r" part! Anyway, Melissa gets on fine with my other 4
cats but will not let me pat her yet. She comes when I call, chooses to
sleep a short way away and watchme work, and has recently started to
walk by me within a few inches. She adores my big male cat, walking around
pressed up against him. But if I even sneak in a touch she jumps away. I tell
her that someday she will be a lap cat. I can dream!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Tracey<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Thedford, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post85" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#85</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 20, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Yvette wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Im from Ontario
Canada and am panicking over here. I had a prescription from a Dr. Heller via
Feralstat and I'm almost out. Has anyone heard how Canadians might be able to
access a prescription from a U.S. vet over the phone?<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi Yvette,<br />
I am from Ontario also and I have been trying to find a solution as
well. I have hit a wall with every vet I contacted. Hopefully feralstat will
be available again soon.<br />
Good luck to you!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post86" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#86</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 20, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Tracey: when you contact a vet
there in Ontario, are you asking for "FeralStat" specifically or
are you asking for megestrol acetate pills or liquid Megace? If you
are asking for "FeralStat" that is a brand name penned by
Dr. Caltabiano, the one who mixed & marketed FeralStat. 99.9% of the vets
in this country will NOT know what FeralStat is--thus they will Google
"FeralStat" and see all the negative & untrue claims put out by
the ACCD and then they won't prescribe it.<br />
<br />
Instead, some vets, especially those dealing with cat fancy show cats, will
know of the use of "megestrol acetate" to control estrus in
felines.<br />
Megestrol Acetate is the SAME thing as FeralStat, just without the
FeralStat name and FeralStat also contained lactose powder--a
NON-necessaryingredient--you only need megestrol acetate pills or
liquid Megace--plain and simple.<br />
<br />
Also, remember these two meds, pills & liquid, are used for appetite
control in humans--check with family members that may have had
cancer or other problems that required these meds--they may have MA pills or
liquid MegAce on hand--it's the same as that for cats/dogs.<br />
<br />
Also, are you just talking to these vets over the phone rather than in
person/in office? If doing so over the phone, you probably will never get a
vet to write you a scrip for megestrol acetate. It's worth a vet visit
to explain to him IN PERSON what you need (megestrol acetate, 20 mg
pills) and WHY you need it (to control estrus in feral colonies).<br />
<br />
Look in your yellow pages for "cat fancy" associations, look for
feline only vets, look for cat fancy breeders (many of them may sell you a
few pills of MA as MA is regularly used by them)...<br />
<br />
Again, you may need to educate your vet on the use of MA for controlling
estrus--point him to the links I posted way back in this thread on proper
dosage & breakdown from the Fairchild website.<br />
<br />
If you Google "buy megestrol acetate" you can see there are
plenty of hits for purchasing, you just need a prescription for it from a
vet...and believe me, it's not too hard to find a vet that will finally
prescribe it for you once you follow proper protocol and talk IN PERSON with
him/her.<br />
<br />
Vets are in business to make $$ too--they will be more considerate of your
plight if you are a paying customer of theirs.<br />
<br />
Look at the online prices of MA pills & liquid and you
will see that we all paid way TOO MUCH in the past for FeralStat. The money
you save on MA pills or liquid will more than pay for an "in
person" vet visit to try to obtain a prescription.<br />
<br />
I highly doubt that the FeralStat website will ever be back up and
running. I wish it would for the sake of everybody here, but I doubt it will.
You don't just stop selling a much wanted product for no reason at all unless
they ran into legal problems.<br />
<br />
Good luck....HTH.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">What A Bogus Solution<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/rockford-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Rockford, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post87" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#87</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 20, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Another Failure From The START<br />
<br />
Sterilizing cats does NOTHING to stop them from the VERY REASON they're not
supposed to be out in nature in the first place. This does NOTHING to stop
them from destroying valuable native-wildlife nor spreading their deadly
diseases to each other, other animals, and even humans.<br />
<br />
To top it off, NO TRAPPING PROGRAM ANYWHERE HAS EVER TRAPPED MORE THAN 0.4%
OF THEM. Always allowing >99.6% to continue to breed out of control
exponentially. I did the research. Even Oregon's amazing 50,000 TNR'ed cats
will have only trapped 0.35% of them by year's-end if you apply cats breeding
rates to all their untrapped cats.<br />
<br />
There's a very good reason that Trap & Kill was JUST AS ineffective as
Trap & Sterilize. They CANNOT be trapped faster than they breed. There is
only ONEsolution. It is the ONLY method that is faster than a species can
out-breed and adapt to. HUNTED TO EXTINCTION. That's a painful and very real
FACT. Now get your heads out of your collectively ignorant and stupid asses
and actually DO SOMETHING about this ecological disaster that you have
created. Trying to sterilize <0.4% of them is NEVER GOING TO WORK.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">11<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">10<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">8<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post88" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#88</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">"Bogus TROLL", take your
ignorance elsewhere. You say "I did the research." What did you
research, Dr. Seuss? People like you with a ROOM TEMPERATURE IQ need to stick
to the Fisher-Price toy research/testing forums....your the kind they use to
see if they can hurt themselves with simple minded toys for simple minded
TROLLS--which is what you are.<br />
<br />
Your village called today...they lost their idiot. Please go home.<br />
<br />
That's all I have to say to you..go hijack other threads with your
Fisher-Price "See & Say" computer. Your mommy's calling...<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">7<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">6<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Tracey<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Thedford, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post90" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#90</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tracey: when you
contact a vet there in Ontario, are you asking for "FeralStat"
specifically or are you asking for megestrol acetate pills or
liquid Megace? If you are asking for "FeralStat" that is
a brand name penned by Dr. Caltabiano, the one who mixed &
marketed FeralStat. 99.9% of the vets in this country will NOT know what
FeralStat is--thus they will Google "FeralStat" and see all the
negative & untrue claims put out by the ACCD and then they won't
prescribe it.<br />
Instead, some vets, especially those dealing with cat fancy show cats, will
know of the use of "megestrol acetate" to control estrus in
felines.<br />
Megestrol Acetate is the SAME thing as FeralStat, just without the
FeralStat name and FeralStat also contained lactose powder--a
NON-necessary ingredient--you only need megestrol acetate pills
or liquid Megace--plain and simple.<br />
Also, remember these two meds, pills & liquid, are used for appetite
control in humans--check with family members that may have had
cancer or other problems that required these meds--they may have MA pills or
liquid MegAce on hand--it's the same as that for cats/dogs.<br />
Also, are you just talking to these vets over the phone rather than in
person/in office? If doing so over the phone, you probably will never get a
vet to write you a scrip for megestrol acetate. It's worth a vet visit
to explain to him IN PERSON what you need (megestrol acetate, 20 mg
pills) and WHY you need it (to control estrus in feral colonies).<br />
Look in your yellow pages for "cat fancy" associations, look for
feline only vets, look for cat fancy breeders (many of them may sell you a
few pills of MA as MA is regularly used by them)...<br />
Again, you may need to educate your vet on the use of MA for controlling
estrus--point him to the links I posted way back in this thread on proper
dosage & breakdownfrom the Fairchild website.<br />
If you Google "buy megestrol acetate" you can see there are
plenty of hits for purchasing, you just need a prescription for it from a
vet...and believe me, it's not too hard to find a vet that will finally
prescribe it for you once you follow proper protocol and talk IN PERSON with
him/her.<br />
Vets are in business to make $$ too--they will be more considerate of your
plight if you are a paying customer of theirs.<br />
Look at the online prices of MA pills & liquid and you will see that we
all paid way TOO MUCH in the past for FeralStat. The money you save on MA
pills or liquid will more than pay for an "in person" vet visit to
try to obtain a prescription.<br />
I highly doubt that the FeralStat website will ever be back up and running. I
wish it would for the sake of everybody here, but I doubt it will. You don't
just stop selling a much wanted product for no reason at all unless they ran
into legal problems.<br />
Good luck....HTH.<br />
James<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thanks James, that is very
helpful.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
id="Picture_x0020_47" o:spid="_x0000_i1048" type="#_x0000_t75" alt="http://static.topixcdn.com/pics/blank.gif"
style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image003.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image005.png" v:shapes="Picture_x0020_47" width="20" /><!--[endif]--></span><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">3<o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
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style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
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o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image005.png" v:shapes="Picture_x0020_48" width="20" /><!--[endif]--></span><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<td style="border-bottom: solid #999999 1.0pt; border-left: none; border-right: none; border-top: solid #999999 1.0pt; mso-border-bottom-alt: solid #999999 .75pt; mso-border-top-alt: solid #999999 .75pt; padding: 6.0pt 3.0pt 37.5pt 6.0pt;" valign="top"><div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post91" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#91</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I hope it helped you Tracey--keep
us posted on your success. Happy Thanksgiving!<br />
<br />
James<o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">True Dat<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/pipestone-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Pipestone, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<td style="border-bottom: solid #999999 1.0pt; border-left: none; border-right: none; border-top: solid #999999 1.0pt; mso-border-bottom-alt: solid #999999 .75pt; mso-border-top-alt: solid #999999 .75pt; padding: 6.0pt 3.0pt 37.5pt 6.0pt;" valign="top"><div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post92" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#92</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">"Many fools stumble over the
truth, but most of them pick themselves up and hurry off as if nothing had
happened." - Winston Churchill<o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 13.5pt; margin-bottom: .0001pt; margin-bottom: 0in; margin-left: 0in; margin-right: 4.5pt; margin-top: 0in;">
<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
id="Picture_x0020_49" o:spid="_x0000_i1046" type="#_x0000_t75" alt="http://static.topixcdn.com/pics/blank.gif"
style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
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</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image005.png" v:shapes="Picture_x0020_49" width="20" /><!--[endif]--></span><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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id="Picture_x0020_50" o:spid="_x0000_i1045" type="#_x0000_t75" alt="http://static.topixcdn.com/pics/blank.gif"
style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image003.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image005.png" v:shapes="Picture_x0020_50" width="20" /><!--[endif]--></span><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">4<o:p></o:p></span></div>
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style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image003.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image005.png" v:shapes="Picture_x0020_51" width="20" /><!--[endif]--></span><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post93" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#93</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I notice that our troll seems to
be transient - he first posts from Buffalo MN and then Sauk Rapids. He also
appears to have multiple persona on this site and is using them to 'judge'
his comments positive and others negative.<br />
<br />
Regardless, these posts are incendiary as well as inaccurate. I have reported
them as abuse.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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id="Picture_x0020_52" o:spid="_x0000_i1043" type="#_x0000_t75" alt="http://static.topixcdn.com/pics/blank.gif"
style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">6<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image003.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image005.png" v:shapes="Picture_x0020_54" width="20" /><!--[endif]--></span><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">4<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post94" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#94</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 21, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Anyone completely ignores the
"humane" part of TNR does not belong to this thread.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">3<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">3<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">TNR IS ILLEGAL<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/pipestone-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Pipestone, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post95" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#95</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 22, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Look up the term TNR advocates
just LOVE to use on how they reduce their feral-cat numbers, their
candy-coating feel-good term of "Death by Attrition". This means
that their cats will die from disease, cat-attacks, animal-attacks, exposure,
road-kill, starvation, and any other means that drastically shortens cats'
lives. They don't die from old-age, you know! ALL their cats suffering for
how many months it takes to die that way. Just because they don't see how
that cat lies there, gasping for air, dying for days, after it's been hit by
a car or survived an animal attack means that it didn't die inhumanely? Is
that how it works with TNR advocates? They didn't see it suffer to death so
it didn't suffer? Are they THIS self-deluded? A cat dying from poisoning is
even more humane than a cat dying from TNR's "attrition" (of which
poisoning by any means; plant, snake, insect, or chemical; is one of the many
methods that falls under the definition of "attrition). In most parts of
this country and the world TNR practices clearly falls under the guidelines
for cruelty to animals, animal-abuse, animal-endangerment, and
animal-abandonment laws. Including being in direct violation of every
invasive-species law in existence.<br />
<br />
Let's not forget how TNR advocates don't hesitate to carve up cats with
scalpels as well as cutting off parts of their ears, from which they have to
heal-up for weeks before they try to survive again. As if letting them die of
"attrition" wasn't bad enough, TNR-advocates start them off by
terrorizing them with traps, cages, and sticking knives into them
first.(Which is also precisely why they can't trap them a 2nd time to keep
them vaccinated.)<br />
<br />
Not only are they cruelly torturing cats, but also all wildlife they inflict
their cats upon. Their cats literally ripping the skin off of and clawing the
guts out of any wildlife to use it as an agonizingly and slowly dying
twitching play-toy for their cats. And as soon as all the "fun" has
drained out of their play-toy, they go on and find another one to torture.
This is no different than if cat-owners went to a pet-store and bought
canaries and hamsters then threw them at their cats to watch their cats tear
them apart for their amusement. What about all the native predators that
depend on all those animals for their ONLY food? Their cats cause all those
animals to STARVE TO DEATH. TNR-advocates' cruelty knows no bounds.<br />
<br />
If you want to raise revenue for your towns and cities in order to deal with
this invasive-species ecological-disaster properly and effectively, start
charging all these TNR advocates with severe fines and imprisonment for
CRUELTY TO ANIMALS AND VIOLATION OF INVASIVE-SPECIES LAWS.<br />
<br />
They're not doing this out of any goodness of their hearts. THEY DON'T HAVE
HEARTS, nor minds. Proved, 100%.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">7<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">7<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">6<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Yvette<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">AOL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post96" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#96</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 22, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">FeralStat update: There may be
hope for all of us hoping for Feralstat's return. I've emailed the lab that
made the product and they've advised the following: "We are working with
the feralstat group to establish a procedure to provide the product. Please
check back with us to the progress."<br />
I will post anything new I find out...<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Floydene Norred<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/flint-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Flint, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post97" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#97</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Nov 22, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">kcook924 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Did the FeralStat
work? I am faced with the same problem as you.<br />
<quoted text><o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi, YES!!!! Feral Stat works. My
mom and I have been rescuing cats for a long time now and this was the only
option left to us because where we live the Vet's charge 300.00 dollars an animal
for spaying the females. When you live on a fixed income and you do not have
any options left just what are you supposed to do?<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">5<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ken<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/slippery-rock-pa"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Slippery Rock, PA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post98" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#98</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 1, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Here is what I received from Feral
Stat via email on 11/29/2011 after I asked if they were offering Feral Stat
again:<br />
I wish the answer was "yes," but not yet. Cutting through
governmental red tape is a long and frustrating process, but we haven't give
up yet!<br />
Sincerely,<br />
Donna Sicuranza<br />
FeralStat, Inc.<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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id="Picture_x0020_67" o:spid="_x0000_i1028" type="#_x0000_t75" alt="http://static.topixcdn.com/pics/blank.gif"
style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image003.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image005.png" v:shapes="Picture_x0020_68" width="20" /><!--[endif]--></span><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">clyde<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post99" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#99</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 2, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">That was supposed to
have been "meds" in my original post above...I will post info later
tonight about how to get antibiotics without a prescription for cats (and
dogs)....gotta head to work right now...will post it later.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Can you please tell us how to get
antibiotics without a prescription for the cats . thanks Clyde from
Kirbyville Tx.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post100" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#100</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 2, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Clyde, due to the idiotic troll
that reared its brainless head on this thread, you will receive the
information via an email to the email address you posted above earlier. The
less information posted here for a while means less food for the
troll....don't feed the troll!:)<br />
<br />
I forgot about not posting the info earlier---check your email.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">clyde<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post101" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#101</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 3, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">That was supposed to
have been "meds" in my original post above...I will post info later
tonight about how to get antibiotics without a prescription for cats (and
dogs)....gotta head to work right now...will post it later.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I got your reply about the
antibiotics ,I am very happy that you know alot about all this stuff.You have
been very helpful,can i get you to tell me about the flea treatments?I really
would appreciate it! CLYDE FROM KIRBYVILLE TX.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Betty McIntyre<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/greenfield-oh"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Greenfield, OH</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post109" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#109</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 14, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">kcook924 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Did the FeralStat
work?<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Feralstat worked wonders but is no
longer available and that is a real shame<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ginger<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post110" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#110</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 14, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James could you email me about the
antibotics and the flea treatment. My cats are feral and one is getting bare
spots on her body. Not sue what she has yet. Up till now all have been really
healthy. Thanks to Feralstat. I gave it to my cats for two years until it
became unavailable. It was a God send, and they were really healthy and had
beautiful coats. I have been lucky since the weather turned cold about the
time I ran out. Don't know yet what to do when it starts to get warm again<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post111" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#111</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 15, 2011</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ginger, bare spots sounds like a
flea allergy. I would be happy to email you the flea & antibiotic info,
but I don't have your email addy. Due to the trolls and spam bots, I will not
post my email here. Give me a day or two and I will create a
"disposable" email address that you can contact me off this
discussion board via email and I can forward the info to you.<br />
<br />
As for alternative to FeralStat when warm weather hits, do your best to get
with a compassionate vet that can prescribe you some MegAce or MA--I
seriously doubt FeralStat will be back any time soon with all the red tape
involved.<br />
<br />
James<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">ginger wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James could you email me about the antibotics and the flea
treatment. My cats are feral and one is getting bare spots on her body. Not
sue what she has yet. Up till now all have been really healthy. Thanks to
Feralstat. I gave it to my cats for two years until it became unavailable. It
was a God send, and they were really healthy and had beautiful coats. I have
been lucky since the weather turned cold about the time I ran out. Don't know
yet what to do when it starts to get warm again<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #5b5b5b; font-family: "helvetica" , "sans-serif"; font-size: 16.5pt;">Tell me when this
thread is updated:<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/alerts/subscribe-thread?forum=med/med&threadid=O5BM504OU9T4PASQ"><span style="background: white; border: solid #dddddd 1.0pt; color: #336699; font-family: "roboto" , "serif"; font-size: 13.0pt; padding: 0in;">Subscribe
Now</span></a><span style="color: #5b5b5b; font-family: "helvetica" , "sans-serif"; font-size: 16.5pt;"> </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p5"><span style="background: white; border: solid #dddddd 1.0pt; color: #336699; font-family: "roboto" , "serif"; font-size: 12.0pt; padding: 0in; text-decoration: none;"> </span><span style="background: white; border: solid #dddddd 1.0pt; color: #336699; font-family: "roboto" , "serif"; font-size: 12.0pt; padding: 0in;">Add to my
Tracker</span></a><span style="color: #5b5b5b; font-family: "helvetica" , "sans-serif"; font-size: 16.5pt;"> <o:p></o:p></span></div>
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<span style="color: #5b5b5b; font-family: "helvetica" , "sans-serif"; font-size: 16.5pt;"> <o:p></o:p></span></div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-27772543330939395862018-07-01T20:32:00.000-07:002018-07-20T14:19:13.591-07:00Topix thread 06152015 posts 132 to 174<table border="0" cellpadding="0" class="MsoNormalTable" style="mso-cellspacing: 1.5pt; mso-yfti-tbllook: 1184; width: 640px;">
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Deborah Jerry - Cuba
City<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/chisholm-mn"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Chisholm, MN</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post153" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#153</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 7, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Will the people out
there that believe in feralstat please, please, email Prince at
info@westlabpharmacy.com & let him know what feralstat has done for you
so that he may get this information to the people addressing the issues of
feralstat. The only way to get feralstat back on the market is if enough
people speak up on the benefits vs. the risks.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post154" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#154</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 9, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I myself do not see
how emailing the pharmacy that compounded Feralstat and touting its wonders
will help to get it back on the market. Why won't Westlab or the Feralstat
Inc. tell us WHY it ceased production so rapidly with no warning?<br />
<br />
What is the truth behind the whole matter and why the vagueness on this
question from Westlab?<br />
<br />
Obviously WestLab stands to gain monetarily if FeralStat is re-introduced. We
all now know there is indeed a cheaper alternative to Feralstat in the form
of MA, which is the main ingredient of Feralstat...the lactose
powder was strictly for masking/taste.<br />
<br />
Since Westlab compounded it, they know the exact formula. Any overseas/offshore
lab could analyze a sample of Feralstat and duplicate it. If
WestLab wants it on the market so bad for the sake of feral colony
caretakers, then why don't they release the actual formula to an overseas
compounding lab? We all know this will never happen as Westlab would not make
money on sales.<br />
<br />
Contrary to popular belief, MA can be purchased from off shore drug sites
without a prescription, not that I am condoning such actions, just stating
that MA is available out there with no RX if one is willing to seek it out on
the web.<br />
<br />
Whoever or whatever entity/regulation pulled Feralstat off the market
obviously knows good and well the BENEFITS of Feralstat as they can look at
the sales figures of the drug itself and KNOW THAT IT WORKS--I don't see how
emailing the pharmacy and beating a dead horse is going to cut through
mammoth red tape/regulations and bring Feralstat back.<br />
<br />
Ask Westlab or Feralstat Inc. WHY it ceased production....WestLab has been
asked this before and NOBODY there will give an answer--they only dodge the
question with vagueness and tell you "we are awaiting approval to begin
dispensing Feralstat"....APPROVAL FROM WHOM?? That is the question I
want answered.<br />
<br />
I myself have given up on Feralstat being re-introduced--I hope I am wrong.
As for now, our ONLY alternative is MA.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post155" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#155</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 9, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">The reason that the
guy at Westlab Pharmacy wanted people to email him about how important
feralstat was to them was to show to the different organizations that oppose
feralstat on the grounds that it has side affects was that feralstat was
working & that the cats were healthy. In otherwords, to debunk these
organization's ideas that feralstat might be harmful to the cats. But most
people feel that the benefits outweigh the risks. These organizations need to
understand that not all areas around the country have the resources to
control the over population of unwanted cats & that feralstat is their
only option. As for me, I'm not giving up on the possibility of feralstat
making a comeback. I hope other people feel the same way & will keep
fighting to get it back on the market.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post156" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#156</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 13, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">(I will attempt this
post one last time.) Only after multiple emails did I finally get a reply
from the FeralStat folks --(I called them an SOB, I put that so you
understand the context of their reply):<br />
<br />
Date: Wed, 1 Feb 2012 14:15:41 +0000<br />
From: info@feralstat.com<br />
Subject: Re: FeralStat<br />
<br />
We are exploring all options for making FeralStat available again as soon as
possible. Until that time, we suggest you continue your Trap, Neuter and
Release efforts, control your temper and clean up your language.<br />
Sincerely,<br />
FeralStat, Inc.<br />
<br />
My response to them: Is there anything those of us who use the FeralStat can
do to help you? Testimonials?<br />
<br />
Prior to FeralStat kittens were being born in this barn that were developing
upper respiratory tract infections and dying a horrible death. I
would get medication from the veterinarian but it usually did not help. One
kitten had such a serious eye infection that her eye ruptured (literally)
when I was putting salve in her eyes. I took her to the vet and she was blind
in the eye that had not ruptured, so I did spend $63 to have her put to
sleep. The farm where these cats are that we feed are on a federal highway.
To TNR is not practical because people are always dumping cats. We have
neutered over 50 cats on our own dime -- it never ends (the dumping), but the
FeralStat stopped the kittens.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post157" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#157</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 13, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">After 3 years with
no kittens, I now have two pregnant ferals. We were ALL happier on FeralStat...
Now the cycle is starting over and I can't find a vet who is willing to 'take
the chance' with a prescription.... I'll keep contacting and trying, but
watching them increase is breaking my heart...<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Jan 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/raymond-sd"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Raymond, SD</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post158" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#158</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 13, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Mommameow wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">After 3 years with
no kittens, I now have two pregnant ferals. We were ALL happier on
FeralStat... Now the cycle is starting over and I can't find a vet who is
willing to 'take the chance' with a prescription.... I'll keep contacting and
trying, but watching them increase is breaking my heart...<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Hi Mommameow,<br />
If you would contact the CatsafratRX online, and ask for a supply of
ovaban, they would be able to help you..or..<br />
If you would email me, perhaps I could offer my help,<br />
My heart goes out to you, as I know how frustrating unwanted kittens can be.
Janey<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post159" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#159</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 14, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Mommameow: Did you
see the "recipe" on page 2 of this thread? I'm presently dealing
with our vet to see if he will create that recipe for us to use.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dolores<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/ellensburg-wa"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Ellensburg, WA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post160" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#160</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 21, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Ok Ladies, I may
have found a solution to our problem! After 100's of hours
researching & using Google, I've found a Non-profit Foundation that
prescribes OvaBan/MegAce. MegAce is human equivalent of megestrol acetate.<br />
It seems as if I've found the same formula as FeralStat itself!<br />
I KNEW I could find a DIY for us to make our own FeralStat if I
kept digging.<br />
The website is:(scroll to bottom half of page)<br />
</span></i><a href="http://www.fairchildcat.org/rich_text_1.html" target="_blank"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">http://www.fairchildcat.org/rich_text_1.html</span></i></a><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><br />
Not sure if they mail order--if any of you call them up, please post your
results here for all of us to share.<br />
Here is the formula they list. I hope I have helped you all out...now that we
seem to have an alternative to FeralStat, it should be easy to get
MegAce/OvaBan from our vets & mix our own & save $.<br />
Here's the info:<br />
Ovaban is utilized as an oral contraceptive to reduce the number of
litters born into a colony<br />
while the cats are being humane trapped and neutered.
The dosages indicated below are low enough to be safe but effective
based on previous studies. We have had great success in preventing HUNDREDS
of Pregnancies in the past 10 years, thus reducing the unwanted cat
overpopulation BY MILLIONS!<br />
NEVER give more medication than is directed. Human Megace (40 mg/ml) is
diluted down to 5 mg per ml with distilled water--this suspension is used
instead of crushing the name-brand Ovaban tablets (1 tablet = 1 ml).<br />
It is very important that you continually evaluate the size of your colony
and insure that you are using the correct dosage and frequency for the size
of your colony.<br />
Total Number of Cats in the Colony - Dosage per colony / Frequency<br />
< 5 cats .5 ml ONCE a week<br />
5-7 cats 1.0 ml ONCE a week<br />
8-11 cats 1.5 ml ONCE a week<br />
12-15 cats 1.0 ml TWICE A WEEK<br />
16-19 cats 1.5 ml TWICE A WEEK<br />
20-23 cats 1.6 ml TWICE A WEEK<br />
24-27 cats 2.0 ml TWICE A WEEK<br />
28-31 cats 2.2 ml TWICE A WEEK<br />
32-35 cats 2.5 ml TWICE A WEEK<br />
36-39 cats 2.8 ml TWICE A WEEK<br />
40 + cats 3.0 ml TWICE A WEEK<br />
NOTE: For the 3cc syringe each line is 0.1 ml whereas on the 6cc syringe each
line is 0.2 ml<br />
1) This medication MUST be mixed in CANNED cat food and served on multiple
plates or dishes (NO PAPER). Use one 5.5 oz can of cat food for every 3 cats
in your colony. It is very important to spread it out on as many plates as
possible so the entire colony is being medicated as evenly as possible.<br />
2)Shake the bottle of medication vigorously as the ovaban settles to the
bottom. It is very important that the ovaban is mixed thoroughly before
dosing to avoid under/overdose.Divide the appropriate dose of medication for
your colony evenly among the plates of food and mix it thoroughly into each
plate of food.<br />
3)DO NOT DISPENSE IN MILK OR MILK PRODUCTS!<br />
4)Store medication with bottle tightly capped in a cool, dry place away from
sunlight.<br />
5)Wash syringe with dish soap and water. Rinse thoroughly. Allow syringe to
air dry on a paper towel.<br />
6)DO NOT SKIP OR MISS A DOSE!If you were unable to dose the cats on your
scheduled day, do so on the very next day and resume your schedule the
following week. For colonies that require a frequency of 2 x per week, the
dosages MUST be spaced out.<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thank you so very
much for this information.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/euless-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Euless, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post161" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#161</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 21, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks to everyone
for understanding! I appreciate the information so much, and just wish I
could find a local vet. I will be trying some of your suggestions to see if
we can get some medication. My colony (abandoned litters from 6 years ago)
had swelled to 16, then with FeralStat we were slowly decreasing... I was at
5!!! Now I have THREE pregnant. I want to have something in place so I can
stop this madness. I have three homes ready for the babies, but you know I'll
have 15 kittens....<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post162" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#162</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 24, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">dolores..I have
ovaban pills & don't know how i would dose them out.I was told to give
eavh cat 1/4th of the pill but was then told that that was too much..How
would i break that up ot dilute them with water if possible??..thank
you..dawnie29@yahoo.com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post163" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#163</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 24, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Per Prince at
Westlab (phone conversation), Feralstat is a trademarked product and not
available though them, but if a vet were to call in a prescription asking for
"feline contraceptive" or "Ovaban" or "Megestrol
Acetate" at 1mg/gm, they would provide either 150 scoops (1 scoop doses
2 cats once a week) for $68.99 or 300 scoops for $89.99.<br />
<br />
I care less about the "why" of Feralstat disappearing than I do
about having an alternative available, which we now have.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/euless-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Euless, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post164" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#164</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 24, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Many thanks to
everyone who has responded with such great information. I especially want to
thank Janey for the referral on Monday the 13th. I have contacted them and
will be receiving the medication soon! There truly are wonderful people out
there who "get" the whole feral cat idea. The cost is more
reasonable than I imagined, and the compassion for our ferals is evident.
Thank you so much!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post165" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#165</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 24, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks to all for
the information on WestLab. What is still the fly in the ointment is that
feral colony caretakers will still need a licensed veterinarian to call
WestLab up and order an RX for MA, Ovaban, or "feline
contraceptive", etc...<br />
<br />
One still CANNOT just call WestLab up and order MA/Ovaban like we did with
Feralstat without a vet.<br />
<br />
The problem all along has NOT been finding an alternative to FeralStat as we
all now know that megestrol acetate/Ovaban is the main active ingredient in
Feralstat. Since Feralstat ceased prescribing, the underlying problem for
feral colony caretakers has been to find a vet that will prescribe MA/Ovaban.
As we have stated over & over in this thread, many vets are NOT aware of
MA/OVaban and are hesitant to prescribe it.<br />
<br />
Just yesterday I received a very short unsigned email from WestLab that
simply stated "Please have your vet contact us regarding
Feralstat."<br />
<br />
Just days before all inquiries to WestLab in regards to Feralstat was that
Feralstat was no longer in production and hoped to be back soon.<br />
<br />
I was puzzled yesterday why WestLab followed up with the short email
instructing me to have my vet contact them about Feralstat.<br />
<br />
The post above clears this up now---apparently WestLab has begun selling
MA/Ovaban in "scoops" and they've worked out their
"dosing" plan similar to Feralstat.<br />
<br />
According to the post, Westlab will sell 300 "scoops" of MA/Ovaban
for $89.99 USD. Doing the math that they reference for 2 feral cats, a
customer should be able to dose 2 feral cats, ONCE A WEEK, for 75 MONTHS at a
total cost of $89.99 USD.<br />
<br />
Again, remember that WestLab has sold you megestrol acetate/OvaBan and only
with your vet's prescription.<br />
<br />
If one has a vet that will indeed call in a prescription to WestLab for
MA/OvaBan, then why not cut WestLab completely out of the equation and save a
lot of money in doing so?<br />
<br />
For example, I am lucky enough to have a vet that will prescribe MA/OvaBan.
He simply calls the local pharmacy up and prescribes it when I need more for
my feral colonies.<br />
<br />
My local drug store charges me $30.00 for 100 count of 20 MG per tablet of
megestrol acetate/Ovaban. Out of that 100 count bottle of pills and using the
same math that WestLab references to take care of (2) cats, once a week, I
can get 800 doses/scoops of MA/OvaBan for $30.00. These 800 doses translates
to 200 MONTHS of "scoops" for $30.00, whereas if my vet calls up
WestLab, their price is $89.99 for 300 doses/scoops of MA/OvaBan which is
only 75 MONTHS of doses/scoops--quite a price difference there for the SAME
medicine.<br />
<br />
So, if any of you have a vet that will indeed call up WestLab, just have him
go through your local pharmacy first to compare prices of MA/OvaBan before
buying from WestLab.<br />
<br />
A 200 ml bottle of "MegAce" which is liquid megestrol acetate sells
at my local pharmacy for $13.00 with a vet RX.<br />
<br />
Remember liquid MegAce is what </span><a href="http://fairchildcat.org/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Fairchildcat.org</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> and the Fairchild vet there is now
using in place of FeralStat or MA/Ovaban tablets as liquid is much easier to
dose/mix than tablets.<br />
<br />
I applaud WestLab for coming up with their "scoop" program, but us
feral colony caretakers are already<br />
spending enough $$ now on taking care of colonies. WestLab can still lower
their prices on megestrol acetate/OvaBan and still profit.<br />
<br />
If my local druggist makes money on a bottle of 100 count MA/Ovaban at $30.00
and $13.00 a bottle for liquid, then I think WestLab could come off their
price of $89.99.<br />
<br />
So, if any of you find a vet that will prescribe for you, check locally first
and compare prices. If WestLab is cheaper than your local pharmacy, then by
all means go with WestLab.<br />
<br />
If you go with a local pharmacy, follow the dosing guidelines as already
outlined here and at </span><a href="http://fairchildcat.org/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">fairchildcat.org</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> and work with your vet that is doing
the prescribing.<br />
<br />
Money is tight in this economy now and as feral colony caretakers, we all
need to save as much as we can to help more ferals.<br />
<br />
Thanks to all for the updated info on WestLab.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Louise Catmaverick<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/kirkland-wa"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Kirkland, WA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post166" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#166</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 25, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">The drugs and
technology are known, but access is difficult for a tangle of reasons. It is
easier to get 'horse' on the streets than something useful like Feralstat.
When our vets declined to order Deslorelin/Suprelorin implants from Peptech,
I pondered that marijuana, a drug with very limited medical benefits, is
being legalized while I can't get drug birthcontrol for my cats! If anyone
knows of a source for these implants, also used to treat Ferret Adrenal
Disease, I'd be greatful. Thanks for the DIY recipe for Feralstat.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post167" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#167</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 25, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I did have a
discussion with a licensed veterinarian at the Feralstat office in order to
get the product. Why certain products require a prescription is frustrating,
but not the decision of Westlab or any other pharmacy. It's an FDA issue I
believe.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post168" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#168</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 25, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara, I too had a
discussion with the vet at Feralstat back in 2008 when I originally got a RX
for Feralstat. The vet there at Feralstat then called up WestLab and Westlab
compounded Feralstat and they shipped it to me. Easy as pie to get a RX for
it back then...everything handled over the phone.<br />
<br />
I wonder if the "ease" of calling up the Feralstat vet is maybe
what caused the demise of Feralstat?<br />
<br />
The demise of Feralstat was probably due to ease of the prescription, plus
ACCD and all the other naysayers of Feralstat probably weighed in to the FDA
as they were not getting "their $hare of the pie" since Feralstat
WORKED contrary to what they proclaimed.<br />
<br />
I sincerely hope all of the feral colony caretakers here can find themselves
a vet that will prescribe Ovaban/MA and have WestLab or whatever pharmacy
fill it for them.<br />
<br />
With the unseasonably warm weather already here in this area of the USA, the
ferals will go into estrus/heat much sooner now--like right now!<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post169" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#169</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Feb 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James..I am using
the 20mg pills for my cats but still unsure as to how much to give..1st i was
told to give each at1/4th of the pill & then was told that that was too
much & each cat should only get 1mg...how do i divide this pill for
maximum effectiveness & also the least amount of side effects...please
email me at dawnie129@yahoo.com<br />
thank you!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post172" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#172</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Mar 2, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Yes, that idea is
totally crazy--Obamacare has absolutely NOTHING to do with the demise of
Feralstat.<br />
<br />
This thread is not a political thread.<br />
<br />
I smell another troll....<br />
<br />
Moderators, please delete the above post so that this thread does not go
south!<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post173" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#173</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Mar 2, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James,<br />
<br />
I was really talking to the person that admitted that they cursed at someone
about Feralstat when I was talking about being careful about blame as far as
availability. We've (feral cat caretakers/advocates) got trouble enough. And
to the woman that brought in politics - please don't !!<br />
<br />
My guess is that the Feralstat going missing is a couple of things. A
trademark dispute, disagreement among the members of the non-profit that was
distributing it, and/or a threatened license violation from someone.<br />
<br />
The first vet I asked about prescribing M.A. actually said to me - wait for
it - that it would be a violation of his license to prescribe to feral cats
and that I should contact Fish & Wildlife. I stayed calm and polite and
gave my experience with them here in Florida, but have been decompressing for
two days since, especially since he allowed me to make and keep a paid
appointment when he knew the answer was going to be "no".<br />
<br />
I checked the wording of the Florida statutes that pertain to veterinary
licenses, and found the following:<br />
<br />
From the DBPR site – Fla 474 (it shall be a violation to.....)<br />
<br />
(y) Using the privilege of ordering, prescribing, or making available
medicinal drugs or drugs as defined in chapter 465, or controlled substances
as defined in chapter 893, for use other than for the specific treatment of
animal patients for which there is a documented veterinarian/client/patient
relationship. Pursuant thereto,the veterinarian shall:<br />
1. Have sufficient knowledge of the animal to<br />
initiate at least a general or preliminary diagnosis of the medical condition
of the animal, which means that the veterinarian is personally acquainted
with the keeping and caring of the animal and has recently seen the animal or
has made medically appropriate and timely visits to the premises where the
animal is kept.<br />
2. Be available or provide for followup care .....<br />
<br />
If there is similar wording in Ct.,- "has recently seen the animal or
made timely visits" - and someone has filed a complaint, that could be
the problem.<br />
<br />
I just had a long time TNR person send me a scorching email about the dangers
of M.A. When I asked her for her source, she replied "a drug book"
- she didn't reply when I asked her about the compared dosage. So, for my own
peace of mind, I'm going to compile a chart of all the studies I can find
involving cats and M.A. My gut feeling is that the risk of being perpetually
pregnant or a kitten born outdoors will still outweigh the risk of the
side-effects. I'll be glad to share it when I'm done. I'm also going to ask
(but don't expect an answer) the large animal welfare groups to let me know
what if any study I've missed, and to share the specific studies that lead
them to come out officially against Feralstat.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post174" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#174</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Mar 2, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara your study
compilation idea sounds great and I myself would like to see it when you are
done. All the naysayers of MA really like to shout out the dangers of MA yet
they cannot really cite any definitive study on the so called dangers!<br />
<br />
They usually lamely refer to the ACCD statement. Most all of these naysayers
will also refuse to listen to those of us that have successfully used MA in
the RIGHT DOSES to effectively control feral populations for YEARS &
YEARS!<br />
<br />
The key to use of MA is "correct dosing" and like EVERY drug on
this planet, there are side effects and dangers when improperly dosed or
abused.<br />
<br />
The naysayers do not know what to say when you ask them like you did about
compared dosages.<br />
<br />
The benefits of MA far outweigh the alternatives as far as feral colonies are
concerned. I've never had one single feral die or become sick from use of
MA--the colony is MUCH healthier because of the use of Feralstat/MA. Had I
not used it on the colony, the ferals would be sick and diseased.<br />
<br />
There is a lot of money riding on the "invention" of an oral
contraceptive for animals and the ACCD is looking with $$ signs in their eyes
too, as well as many licensed vets who do NOT want to see such a thing.<br />
<br />
I'm looking forward to your study compilation as I'm sure many others here
are too. Thank you!<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #5b5b5b; font-family: "helvetica" , "sans-serif"; font-size: 16.5pt;">Tell me when this
thread is updated:<o:p></o:p></span></b></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ommameow<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/dallas"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post132" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#132</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 8, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Please post the number- I'm having
no luck finding a local vet to help yet. And I had a feral in heat last week-
I'm panicking!!<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post133" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#133</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 8, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi janeyjan,<br />
I feed the contraceptive year round. The kittens start here late
February or early March which means they are conceived in December/January.
So, I prefer to feed it year round rather than run the risk of 'missing'
someone at a critical time. The weather here is unpredictable and winters can
be mild, especially when compared with the Northern climates.<br />
<br />
5 mg - which is 1/4 of a 20 mg tablet - is more MA than the Feralstat was
giving. Part of the concern with MA is the side effects - which do
occur - but they happen at the higher doses. My vet was totally unfamiliar
with using this low of a dose so I suspect the pharmacist is as well. I am
feeding a colony of 11 with a total dosage of 7.5 mg of MA (same as with
FeralStat), so you may wish to make up the liquid suspension as James
outlined above and give your cat a smaller dosage to reduce the risk of
serious side effects. The smallerdosages have shown themselves to
be effective from all of our shared experiences over the last few years, so I
think you might want to feed as low a dose as does the job.<br />
<br />
Instead of publishing the Pharmacist's phone number, why not just include
the link to their website? That way people can check on line
first and if they are serious, follow up with a phone call. I don't
think the Pharmacist would want to be inundated with calls as might happen if
the number is posted. The websitelink is probably safer way to go for
him.<o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/janeyjan" title="See janeyjan's profile"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.5pt;">janeyjan</span></b></a><b><span style="font-family: "times new roman" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Jan 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/clark-sd"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Clark, SD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post134" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#134</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 8, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Mommameow wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Please post the
number- I'm having no luck finding a local vet to help yet. And I had a feral
in heat last week- I'm panicking!!<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">HI...<br />
Why don't you email me , and I will give you the phone
number. you can do thisby using this email address.....<br />
jhowardson@itctel.com<br />
jane<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post135" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#135</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 9, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">The link to the
catsafratsRX site is as follows:<br />
</span><a href="http://www.catsafratsrx.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.catsafratsrx.com/</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
The pharmacist there is Dr. Bruce Isenberg. If you shop his catalog, you
will have to search on the word "Ovaban" and it comes up as
"megesterol" (note the extra letter "e" in between the
"t" & "r". If you search for "megestrol
acetate" on his site, you will get nothing. The current price of
his Ovaban tablets shows to be $13.00 for 6 tablets of 20 mg each at time of
this post.<br />
<br />
He may give a discount for larger quantities of pills--I don't know.<br />
<br />
You will still need a scrip for it to purchase from him as I understand or
name of a referring veterinarian. At least we know Dr. Isenberg will sell it
and is sympathetic to feral cat rescuers with proper prescription protocol
followed.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post136" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#136</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 12, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">recently wrote Fairchild about
helping with the dosage & this was their response...Not sure if this
helps since they recommend 5mg for 5-7 cats..I was giving eacj cat the
Feralstat indivdually but thought I would pass this along ......... Hi..Was
wondering if someone can give me a little help..Recently was given Ovaban for
my strays to replace Feralstat & not wuite sure of the dosage..Was giving
each cat 1/8th teaspoon but now I am told to give 1/4 pill per cat..I would
rather crush the pills & mix with food rather than dilute with water..Can
someone PLEASE help me..Ive read that the giving too much can cause side
effects so i'm trying to give the least amount that will still
work..THANKS for any help<br />
LikeUnlike ·· Tuesday at 2:35pm ·<br />
<br />
Fairchild "Feral Friends" Foundation We use a low dose....5 mg
should treat 5-7 cats. For larger colonies we recommend dosing twice a week
to ensure that all cats are getting the birth control. We use human megace
liquid and dilute it down to 5 mg/ml for huge cost-savings over name-brand Ovaban.<br />
22 hours ago · LikeUnlike.Fairchild "Feral Friends" Foundation <
5 cats .5 ml ONCE a week<br />
5-7 cats 1.0 ml ONCE a week<br />
8-11 cats 1.5 ml ONCE a week<br />
12-15 cats 1.0 ml TWICE A WEEK<br />
16-19 cats 1.5 ml TWICE A WEEK<br />
... 20-23 cats 1.6 ml TWICE A WEEK<br />
24-27 cats 2.0 ml TWICE A WEEK<br />
28-31 cats 2.2 ml TWICE A WEEK<br />
32-35 cats 2.5 ml TWICE A WEEK<br />
36-39 cats 2.8 ml TWICE A WEEK<br />
40 + cats 3.0 ml TWICE A WEEKSee More<br />
22 hours ago · LikeUnlike.Fairchild "Feral Friends" Foundation For
our chart 1 ml = one 5 mg tablet<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Florida<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post138" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#138</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 24, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thanks to everyone for their
information on megestrol acetate. I have been using Feralstat on a colony of
15 here in Florida for a year with no births and no noticeable side
effects. My prescription is nearly gone and I was not sure what I was going
to do. Appreciate everyones input.<br />
<br />
Also, before beginning to use Feralstat I looked carefully at the studies I
could find on PubMed for megestrol acetate, and the few I could find that
reportedside effects gave no information as far as the total number of
cats being treated with MA, so it was impossible to tell if side
effects happened in 1%, 10% or 100% of cases. That's why I have a hard
time swallowing the dire warnings out there on the web about Feralstat.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Carol<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/bryan-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Bryan, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post139" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#139</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 30, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">To Julie in Arizona-I ahve used
Feralstat for 2 1/2 years--can you tell me where to get it now?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post140" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#140</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 30, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi Carol,<br />
<br />
If you take a bit of time and go back and read over this thread from the
beginning you will get an appreciation of what is involved to get the
medicine you can use in place of Feralstat - megestrol acestate also known as
Ovaban. Feralstat is no longer available and hasn't been since August of
2011. We don't know if it will ever be available again, but that doesn't mean
your colony has to go without contraceptive control. You will just have to do
a little bit more work than you did to get the Feralstat as you will need to
convince a local veterinarian to prescribe megestrol acetate/Ovaban for you
and then prepare the medicine to the correct dosage yourself. All of the
information is available in this thread. James' posts are especially
important. I used to use FeralStat as well and now, with the assistance of my
vet, am managing my colony with megestral acetate/Ovaban. So, good luck :-).<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ginger<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post141" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#141</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 30, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Well, I'm still waiting for some
help. I know at least one of my cats has been in heat. I cannot find a vet to
help me here. Is there a vet anyone knows to help me. I'm losing my mind
here. If I don't get help soon, I guess I will just ignore the whole colonie,
and hoope they go away. It seems that is what every one else does in this
town.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/janeyjan" title="See janeyjan's profile"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.5pt;">janeyjan</span></b></a><b><span style="font-family: "times new roman" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<a href="http://www.topix.com/member/profile/janeyjan"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt; text-decoration: none;"><!--[if gte vml 1]><v:shape id="Picture_x0020_37"
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Jan 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/raymond-sd"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Raymond, SD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post142" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#142</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 30, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">ginger wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Well, I'm still
waiting for some help. I know at least one of my cats has been in heat. I
cannot find a vet to help me here. Is there a vet anyone knows to help me.
I'm losing my mind here. If I don't get help soon, I guess I will just ignore
the whole colonie, and hoope they go away. It seems that is what every one else
does in this town.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi Ginger,<br />
If you email me, I might be able to help you obtain some OVaban.<br />
Janey<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/norwalk-oh"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Norwalk, OH</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post143" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#143</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 31, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have used feral stat for three
years on our farm and it works!!! Have had no litters in three years! And
no side effects!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Deborah Jerry - Cuba City<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/chisholm-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Chisholm, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post144" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#144</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 1, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">To anyone still looking for
feralstat- I just spoke with someone at Westlab Pharmacy regarding feralstat.
He said that they were still working on getting it back on the market. And
for people to send emails regarding feralstat & how it is affecting them.
Then he would collect the emails & get them to the people addressing the
issues on feralstat. So please send an email to info@WestlabPharmacy.com
Attention: Prince<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Deborah Jerry - Cuba City<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/chisholm-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Chisholm, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post145" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#145</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 1, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">When I posted a comment earlier
this evening I forgot to add that you should put the RX# in the email if you
send one to info@westlabpharmacy.com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Deborah Jerry - Cuba City<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/chisholm-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Chisholm, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post146" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#146</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 1, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I hope people will email
info@westlabpharmacy.com with their comments regarding feralstat. Their
comments on feralstat may help get it back on the market.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post147" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#147</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 2, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">will DEFINITELY be emailing
Westlab..Feralstst was so easy to use..I recently got Megestrol Acetate but
the dosage I was prescibed is higher than it needs to be..I want Feralstst
back!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ginger<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post148" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#148</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 2, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Janey I can not get my email to go
through to you. Could you e mail me about the info? gweimer@atlanticbb.net<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">evvabeing<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Toronto, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post149" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#149</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">MEGESTEROL (Ovaban) 20 mg
tablets/6 tablets<br />
$13.00<br />
<br />
</span><a href="http://catsafratsrx.com/catalog/index.php?main_page=product_info&cPath=12&products_id=50" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://catsafratsrx.com/catalog/index.php...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">evvabeing<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Toronto, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post150" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#150</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">evvabeing wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">MEGESTEROL (Ovaban)
20 mg tablets/6 tablets<br />
$13.00<br />
</span></i><a href="http://catsafratsrx.com/catalog/index.php?main_page=product_info&cPath=12&products_id=50" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">http://catsafratsrx.com/catalog/index.php...</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">also known as Ovarid<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">evvabeing<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Toronto, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post151" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#151</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">evvabeing wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"><quoted text><br />
also known as Ovarid<o:p></o:p></span></i></div>
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<a href="http://www.viovet.co.uk/Prescription_Drugs-Prescription_Drugs_M_-_Q-Ovarid/c1_34_2121/category.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.viovet.co.uk/Prescription_Drugs-Pr...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">evvabeing<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Toronto, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post152" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#152</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 7, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">i got this response from
info@feralstat.com...<br />
<br />
The FeralStat office is closed. We cannot provide the product at this time.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p7" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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thread is updated:<o:p></o:p></span></b></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"> </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p8"><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;">Next</span><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt; text-decoration: none;"> </span></a><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"> </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p17"><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;">Last</span><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt; text-decoration: none;"> </span></a><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"><o:p></o:p></span></div>
tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-88758884528713627922018-07-01T20:27:00.000-07:002018-07-20T14:19:40.204-07:00Topix thread 06152015 posts 175 to 220<table border="0" cellpadding="0" class="MsoNormalTable" style="margin-left: -1.5pt; mso-cellspacing: 1.5pt; mso-yfti-tbllook: 1184; width: 642px;">
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post220" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt; text-decoration: none;"><br />
</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#220</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 18, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara:<br />
<br />
3 words: WOW! THANK YOU!<br />
<br />
Everyone reading this thread should thank you for your obviously
well researched findings & data.<br />
<br />
Every naysayer of Feralstat/MA should read your findings and see that
the side effects of MA are from overdosing. Veterinarians should
also read your studies and see how miniscule doses of MA will
control feral populations with no harmful effects.<br />
<br />
I echo the same sentiments that Kathryn41 posted just above this post.<br />
<br />
Again, I thank you for your dedicated and well-researched studies...thank you
for sharing them here. I love your website!<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post221" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#221</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 18, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James and Katherine -
thank you for your generous comments. I suppose there's a chance that there's
a database of information not available to laypeople that would show
something different than I found - I'd certainly like to know from veterinarians
if that's the case. In a way I'm hoping that's the case because the thought
that Alley Cat Allies and Best Friends have written off Feralstat
as dangerous with the same information that I found is unimaginable. To have
a tool that could easily, quickly, and inexpensively stop the cycle of
reproduction in outdoor cats and save millions of lives - and NOT investigate
it further, taking only the word of ACC&D and a sentence from drug
manuals - that's just too upsetting to consider.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post222" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#222</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 20, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Here is a link to ACC&D's
postion paper on megestrol acetate.<br />
<br />
</span><a href="http://www.acc-d.org/ACCD%20docs/PPPP-MegestrolAcetate.pdf" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.acc-d.org/ACCD%20docs/PPPP-Megestr...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
While not an endorsement, it's much more middle of the road than the
statement I recall from 2 years ago.<br />
<br />
I'd also suggest looking at the presentation materials from the most recent
ACC&D symposium. I was struck by few of the methods under investigation
are for cats.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn41<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post223" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#223</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 20, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">That statement from ACC&D is
still from 2009 and is based on effective dosesof 2;5 to 5 mg per week
per cat - which is still 2 1/2 times the dosage that we use and
that has proven effective with our feral colonies.<br />
<br />
My vet was surprised at the low dosages that we use, and our own results from
our colonies prove that our lower dosages are effective for the purposes we
use it - contraception. While we don't know if colony members have
the side effectsunless we encounter an obviously sick animal, feral cats
lives are harsh to begin with. If a colony member goes missing, I am more likely
to suspect coyotes or a car than pyometra as those are far greater
probabilities. There does not yet seem to be a position paper that
actually discusses the situation we use for our feral colonies - and has been
used for many years successfully in Europe - low dosages of about 1 mg per
animal per week. It is the side effects at those dosages we need to
be researching before everyone starts nay-saying its safety and
effectiveness.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post224" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#224</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 20, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi James..Sorry I havent answered
your question as to how my kitties are but I havent been here lately..Yes
they're still all here..I went to the building dept & explained the
situation & she told me to see if I could try to keep them out of the
neighbors yard..Then she said if she got any more complaints we would have to
take it from there..I also spoke to my neighbor who I think may have
complained..I told her how I was trying to keep the cats out of her yard
& she appreciated that but she also told me SHE HATED CATS!..which isn't
good..also her sister lives rght next door to her & I assume the cats go
to her yard as well * her brother owns the house my neighbor lives in..I
figure one day they'll all get together & complain & then i'll really
have a problem..THANKS for asking..I also keep seeing you post about dsage of
the Megestrol..I give each cat it individually..i've been crushing it up
& mixing it in the food & they don't seem to mind at all but i'm
still concerned about the dosage..how would I feed each cat individually
& how much??..thank you fro all your informative info!<br />
Dawn<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post225" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#225</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 20, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Dawn, Thank you for the update.
I'm glad you still have the kitties. You may wish to remind your neighbor
that "hates cats" that feral colonies do keep the ecosystem in
balance for mice, rats, snakes, & other small rodents. Would your
neighbor rather have rats & mice in their home or a feral cat in their
yard? How about a snake roaming in their yard where their children play or a
feral cat in the yard catching the snakes..& remind them most ferals are
nocturnal so they won't be "bothered" by them as much in the daytime.<br />
<br />
However, some neighbors are just downright ill hearted & nothing you say
will convince them to appreciate animals...man tends to forget that animals
were on this Earth before humans.<br />
<br />
As for your dosage, if it has been working for you, keep doing it..You
said you have about 15 ferals--about 7 females...just try to ensure the
females get the MA--it's OK if males eat it though. A liquid suspension as
I've described will "coat" the food more evenly than sprinkling dry
crushed MA on the food. I prefer liquid MA suspension, but remember the
original FeralsStat was a powder, so if it works for you, keep doing it. The
liquid suspension is what caretakers & vets at Fairchild have proven
works & is easiest to dose in small amounts.<br />
<br />
The main thing we all need to remember is not to overdose.<br />
<br />
As for the ACCD statements on MA, I don't feel like ACCD or any other major
organization will ever study small dosage efficacy for
contraception in the manner that we all use it for simply because of
economics--or rather MONEY.<br />
<br />
There is no big money in MA..it's cheap & is not patented like say
Esterisol will be when it hits the market this year for dogs.<br />
<br />
You can bet if a drug does hit the market for feral cats, it will be
expensive & will be patented to prevent generics for several years. There
will be expensive TV ads & marketing campaigns & lots of promo
material in every veterinary office in the country...Big pharmaceutical
companies market "DOT COM" drugs everyday on websites like </span><a href="http://lipitor.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">lipitor.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> etc...Those
TV ads during the afternoon that run ad nauseum targeting senior citizens are
not free...If a feral cat contraceptive does become available, it WILL be
expensive, & ACCD will have a piece of the pie as well as other big name
players.<br />
<br />
I can buy 100 tablets of MA 20mg, for less than $30.00--not much money in
that for the drug companies, thus the continued suppression of MA as a
contraceptive & the non-existent studies to prove it works like the way
we use it. It will take an independent research firm to study MA
the way we use it--ACCD & Big Pharma will surely never do it.<br />
<br />
When we as caretakers try to explain the advantages of MA for feral colonies,
we are usually met with opposition by people quoting the same ol' tired ACCD
statement you find when you google "Feralstat" or MA. They complain
that thefood is left out for other animals to eat, blah, blah...I myself
have always had the feral colony lick & clean their plates--not ever
leaving any doctored food for raccoons or other wild animals!<br />
I've never seen any other wild animals hanging around waiting for me to show
up with food like the ferals do either. Plus, I always pick up my plates
& leave no trash behind once the ferals have their medicine.<br />
<br />
At least we have access to MA now that Feralstat is gone--I'm just glad the
we had Fairchild's reference to use for proper low dosing of MA for
ferals.<br />
<br />
I myself dream of a simple pill that could chemically sterilize cats &
dogs for life, but I know I'll never see it in my lifetime.<br />
<br />
If I do, I wouldn't be able to afford it--that's for certain.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post226" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#226</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 21, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn (sorry about mis-spelling
your name earlier)- thanks for the clarification on the ACC&D statement
and reiterating the point about the dosage.<br />
<br />
Your question about the incidence of pyometra in the general cat population
is an excellent one - if you ever run across that number I'd be very
interested.<br />
<br />
Barbara<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Kathryn41 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">That statement from ACC&D is still from 2009 and is based
on effective doses of 2;5 to 5 mg per week per cat - which is still
2 1/2 times the dosage that we use and that has proven effective
with our feral colonies.<br />
My vet was surprised at the low dosages that we use, and our own results from
our colonies prove that our lower dosages are effective for the purposes we
use it - contraception. While we don't know if colony members have the side
effects unless we encounter an obviously sick animal, feral cats lives are
harsh to begin with. If a colony member goes missing, I am more likely to
suspect coyotes or a car than pyometra as those are far greater
probabilities. There does not yet seem to be a position paper that actually
discusses the situation we use for our feral colonies - and has been used for
many years successfully in Europe - low dosages of about 1 mg per animal per
week. It is the side effects at those dosages we need to be researching
before everyone starts nay-saying its safety and effectiveness.<o:p></o:p></span></i></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post227" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#227</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 21, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James -your point about the
economics of any drug is spot on. Discouraging, but absolutely correct.<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Dawn, Thank you for the update. I'm glad you still have the
kitties. You may wish to remind your neighbor that "hates cats"
that feral colonies do keep the ecosystem in balance for mice, rats, snakes,
& other small rodents. Would your neighbor rather have rats & mice in
their home or a feral cat in their yard? How about a snake roaming in their
yard where their children play or a feral cat in the yard catching the
snakes..& remind them most ferals are nocturnal so they won't be
"bothered" by them as much in the daytime.<br />
However, some neighbors are just downright ill hearted & nothing you say
will convince them to appreciate animals...man tends to forget that animals
were on this Earth before humans.<br />
As for your dosage, if it has been working for you, keep doing it..You said
you have about 15 ferals--about 7 females...just try to ensure the females
get the MA--it's OK if males eat it though. A liquid suspension as I've
described will "coat" the food more evenly than sprinkling dry
crushed MA on the food. I prefer liquid MA suspension, but remember the
original FeralsStat was a powder, so if it works for you, keep doing it. The
liquid suspension is what caretakers & vets at Fairchild have proven
works & is easiest to dose in small amounts.<br />
The main thing we all need to remember is not to overdose.<br />
As for the ACCD statements on MA, I don't feel like ACCD or any other major
organization will ever study small dosage efficacy for contraception in the
manner that we all use it for simply because of economics--or rather MONEY.<br />
There is no big money in MA..it's cheap & is not patented like say
Esterisol will be when it hits the market this year for dogs.<br />
You can bet if a drug does hit the market for feral cats, it will be
expensive & will be patented to prevent generics for several years. There
will be expensive TV ads & marketing campaigns & lots of promo
material in every veterinary office in the country...Big pharmaceutical
companies market "DOT COM" drugs everyday on websites like </span></i><a href="http://lipitor.com/" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">lipitor.com</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"> etc...Those TV ads during the afternoon that run ad
nauseum targeting senior citizens are not free...If a feral cat contraceptive
does become available, it WILL be expensive, & ACCD will have a piece of
the pie as well as other big name players.<br />
I can buy 100 tablets of MA 20mg, for less than $30.00--not much money in
that for the drug companies, thus the continued suppression of MA as a
contraceptive & the non-existent studies to prove it works like the way
we use it. It will take an independent research firm to study MA the way we
use it--ACCD & Big Pharma will surely never do it.<br />
When we as caretakers try to explain the advantages of MA for feral colonies,
we are usually met with opposition by people quoting the same ol' tired ACCD
statement you find when you google "Feralstat" or MA. They complain
that the food is left out for other animals to eat, blah, blah...I myself
have always had the feral colony lick & clean their plates--not ever
leaving any doctored food for raccoons or other wild animals!<br />
I've never seen any other wild animals hanging around waiting for me to show
up with food like the ferals do either. Plus, I always pick up my plates
& leave no trash behind once the ferals have their medicine.<br />
At least we have access to MA now that Feralstat is gone--I'm just glad the
we had Fairchild's reference to use for proper low dosing of MA for ferals.<br />
I myself dream of a simple pill that could chemically sterilize cats &
dogs for life, but I know I'll never see it in my lifetime.<br />
If I do, I wouldn't be able to afford it--that's for certain.<br />
James<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn41<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post228" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#228</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 21, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Here are some interesting studies
that try to show some of the rates of certain conditions in spayed and
unspayed animals (cats and dogs). It appears that dystocea - the inability of
the animal to deliver a litter unassisted average at5.8% for cats - that is a
very risk for feral moms which lead to a painful death of the mother and the
litter. Spaying - and contraception - prevents that. Unfortunately this
summary states that there aren't any figures available on the rate of
pyometra in the general non-spayed population.<br />
</span><a href="http://www.skeptvet.com/index.php?p=1_23_Benefits-Risks-of-Neutering" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.skeptvet.com/index.php...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
This study is really interesting</span><a href="http://www.avma.org/avmacollections/feral_cats/javma_221_8_1136.pdf" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.avma.org/avmacollections/feral_cat...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> and involves monitored feral cat colonies in
Florida. 19% of the females were pregnant when examined with a seasonal
average of 47%..4% of the adult females had pyometra and were spayed or put
down.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post229" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#229</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 21, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thanks - I'll look those over more
carefully shortly -.4% jumped out at me from the Fla. study -- that was the #
in the Oslo study in the articles I pulled from PubMed.(1 of 244 had
pyometra.)<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Kathryn41 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Here are some interesting studies that try to show some of the
rates of certain conditions in spayed and unspayed animals (cats and dogs).
It appears that dystocea - the inability of the animal to deliver a litter
unassisted average at5.8% for cats - that is a very risk for feral moms which
lead to a painful death of the mother and the litter. Spaying - and
contraception - prevents that. Unfortunately this summary states that there
aren't any figures available on the rate of pyometra in the general
non-spayed population.<br />
</span></i><a href="http://www.skeptvet.com/index.php?p=1_23_Benefits-Risks-of-Neutering" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">http://www.skeptvet.com/index.php...</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"><br />
This study is really interesting </span></i><a href="http://www.avma.org/avmacollections/feral_cats/javma_221_8_1136.pdf" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">http://www.avma.org/avmacollections/feral_cat...</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"> and involves monitored feral cat
colonies in Florida. 19% of the females were pregnant when examined with a
seasonal average of 47%..4% of the adult females had pyometra and were spayed
or put down.<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post230" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#230</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James, why would it be so terrible
for a raccoon to eat leftover food that has MA? Last night we had 4 raccoons
come for a visit -- it was actually quite comical as they tried to take the
tote that has the dry cat food. They tipped it over, rolled it, actually
tried to take it with them, but they couldn't get the lid open. I will never
hurt/trap/chase away a raccoon, but I wouldn't mind if their numbers
decreased with the aid of MA.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn41<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post231" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#231</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I would think that most colonies
wouldn't have a problem with left over medicated food. The amount given is so
small that you try to concentrate it enough in the wet food that then gets
eaten up.<br />
<br />
My colony gets medicated food on Tuesday mornings between 6:30 and 7 am. I
use one large can of catfood to mix in the megestrol. There are 11 serving
dishes for food. I put their dry food down first then each dish gets a glop
(about a tablespoon) of medicated food on top. The cats start to eat the
medicated food right away and finish that before they eat the dry food. I
take note of who is there and eating and watch to make sure all of them
actually do eat. They run around from dish to dish, alert and on guard to any
movement outside of the area. Once I see that all have eaten some medicated
food I leave them to finish. I go back around lunch time to 'check'. There
may be some dried food left but there is never any of the medicated food
left. There wouldn't be any wildlife around during the day that would get to
any medicated food that is left out. There are opossums, raccoons,fox, coyote
and birds in the area. I do know that the birds sometimes finish up any dry
food that is left but the mammals don't come out during the day so I think
with careful management it is unlikely that wildlife would get any of the
food. The only problem I might have is if a neighbourhood dog gets loose -
they aren't allowed to be loose here - and accidentally stumbles on the
dishes before the cats finish them. It hasn't happened yet but I guess it is
always a possibility.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post232" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#232</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">May 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen, I think you misunderstood
my post about there being left over medicated food for raccoons. I myself
have no problem with with raccoons eating medicated food dosed with MA as the
amount of MA is miniscule. I was actually pointing out that the ACCD &
other nay-sayers of MA always use this as a point to discourage the use of
Feralstat/MA. They always say that we have no control of what other animals
have access to the medicated food and that is what they complain about--that
we can't control what other animals actually eat the dosed food.<br />
In a sense they are correct, but I was just stating that my colony of kitties
always lick their plates clean, thus not leaving anything for the raccoons
and possums and other wild animals.<br />
<br />
As for feeding raccoons, I myself buy a 50 lb bag of dog food each week and I
don't own a single dog. I put the dog food out in my back yard for the coons
& possums at night plus I keep water out for them just so they have
something to eat & drink in this drought ridden area. Deer & fox love
the dog food too, but the coons seem to always hog it. On a side note,
raccoons are very dexterous with their hands--many times more dexterous than
a human-a raccoon can feel in the bottom of a shallow stream & tell if he
has a small rock or a mussel shell. A raccoon can do just about anything with
their hands except pick a lock! LOL.<br />
<br />
I don't know if MA works on those animals as I never tried it, I save the
medication for feral cats.<br />
<br />
I myself have a big heart and would not dream of turning any animal away that
was hungry. Raccoons do provide a good nocturnal entertainment for us humans
if they are trying to get at some food, plus they will eat all your table
scraps--no need to waste the scraps in a garbage disposal--the coons will
sure eat it.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post233" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#233</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 13, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi James, it was this comment in
your post: They complain that the food is left out for other animals to eat,
blah, blah...I myself have always had the feral colony lick & clean their
plates--not ever leaving any doctored food for raccoons or other wild
animals!<br />
<br />
And that is why I asked the question about other animals (namely
coons)ingesting the MA -- what would it do to them that the PETA folks complain
about doctored food being left over.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post234" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#234</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 13, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen, I really don't think the MA
would do any harm to a raccoon or any other animal that might ingest it from
leftover feral cat food. Remember MA has been given to both dogs & cats
in the past by veterinarians, thus we can only assume that it is not harmful
to possums, coons, etc. Plus, by the time the feral colony gets finished with
the doctored food, there's usually always very little, if any, food left for
the scavengers to find & eat.<br />
<br />
The argument against MA/Feralstat was by ACCD and the leftover doctored food
left for other animals was their case against the use of MA as we use it.<br />
<br />
Again, I think the ACCD is totally against MA/feralstat because there is
absolutely zero mega-dollars for them (ACCD) and other powerful lobbyist
groups for vets & other special interest groups who all want a piece of
the cash cow when a birth control pill for cats & dogs is invented. It's
kind of like these "new school" doctors that won't prescribe simple
penicillin for minor ailments but instead they prescribe a more expensive
"DOT COM" drug instead for $$ kickbacks from the pharmaceutical
company. You never see clocks, calendars, note pads, & other advertising
gimmicks in doctor or vet offices for the "old school/inexpensive"
drugs--you only see them for the new expensive ones.<br />
<br />
All of us here know in our hearts that MA/Feralstat works for our purposes,
it's safe, and it is inexpensive. The ACCD & naysayers will do everything
they can to discourage us from saving feral colonies by using the inexpensive
MA.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/albuquerque"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Albuquerque, NM</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post235" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#235</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 13, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Has anyone ever thought about
going to </span><a href="http://change.org/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">change.org</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> and
starting a petition to get FeralStat back?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post236" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#236</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 14, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">The </span><a href="http://change.org/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">change.org</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> idea
is a good one, but I don't know if it would be effective as we still do not
know WHY the sellers of Feralstat stopped selling it so abruptly and they
have remained silent on this. I can only suspect the problem was perhaps the
ease of obtaining it over the phone, but again, that is strictly conjecture
on my part.<br />
<br />
The inventors of Feralstat would best be suited to start the petition, but
first they should disclose WHY they stopped selling it.<br />
Quite frankly, I am happy with my use of MA on my colony. MA by the 100 count
bottle is MUCH cheaper than what I paid for Feralstat. The results are the
same.<br />
The only advantage Feralstat had over MA was that it was '"easy" to
get from its inventors by simply a short phone call interview. And again,
this is what I myself suspect caused Feralstat to suddenly
"disappear"--the ease of obtaining it. MA requires a RX from a
local vet, but once you find a vet willing to prescribe it, you really don't
need Feralstat anymore.<br />
<br />
If a Feralstat petition is started by its inventors, I'll gladly sign it.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post237" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#237</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 14, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">There is so much mis-information
out there now on MA/Feralstat. I had some free time this morning &
decided to google the word feralstat. I am amazed at the number of 'experts'
out there quoting the same old ACCD statement and then giving out false info
on what happened and why to Feralstat..<br />
<br />
There's a site called </span><a href="http://justanswer.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">justanswer.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> where one can pay for a veterinarian to answer their
questions. There are lots of feral caretakers like us that are in dire need
of MA/Feralstat & they resorted to Justanswer and their experts. Some of
the vets replied with honest and correct answers about MA & how to obtain
it. Some of them however "sold" the buyer erroneous information and
this shows the ignorance of many vets in this country when it comes to MA.<br />
<br />
</span><a href="http://www.justanswer.com/cat-health/644oy-use-feralstat-birth-control-barn-cats-works.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.justanswer.com/cat-health/644oy-us...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
The 30+ year experienced vet replied that Feralstat is still available as of
148 days ago. We all know Feralstat disappeared summer 2011. The expert
'vetmom4" took the $28 payment from the feral caretaker, which would
have just about bought a bottle of MA, & told her any vet should be able
to order Feralstat. The expert did not even mention the generic option of
MA/Ovaban,& as we all know, ask a local vet about Feralstat, & most
of them are clueless on what it is/was.<br />
<br />
Another look at </span><a href="http://justanswer.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">justanswer.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> & I find this "expert" Dr. Gary:<br />
</span><a href="http://www.justanswer.com/pet-cat/62tep-client-looking-purchase-feralstat.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.justanswer.com/pet-cat/62tep-clien...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
He takes the money & basically quotes the same old ACCD statement and
says "they" pulled Feralstat off the market--yet he cites NO
STUDIES at all to prove this!<br />
<br />
</span><a href="http://www.justanswer.com/pet-cat/642yo-prescription-feralstat-staten-island.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.justanswer.com/pet-cat/642yo-presc...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
In the one above, Dr. Gary again takes the money & tells the customer
"The FDA" pulled Feralstat--I don't believe the FDA did this as Dr.
Gary again cites no references to prove it. He does cite the same old Alley
Cat/ACCD statement made while Feralstat was still on the market. It's obvious
Dr. Gary is just googling Feralstat & reading the ACCD statement rather
than really RESEARCHING the proven uses of MA.<br />
<br />
Another justanswer here:<br />
</span><a href="http://www.justanswer.com/pet-cat/5zymt-feralstat-no-longer-available-small-colony.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.justanswer.com/pet-cat/5zymt-feral...</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
This customer however does not accept the expert's first answer when the vet
did not even answer the question the caretaker asked. When the customer
refused payment of the answer, at least this vet did go back and reference
"MA" so maybe the customer will google MA & happen upon our
discussion here & find real answers.<br />
<br />
Dr. Gary harped on side effects of MA but cited no studies, plus he must be
clueless that the side effects of MA are from OVERDOSING--no side effects if
MA is used as we all now know & do here.<br />
<br />
Barbara here did an excellent research study herself that I wish these
"expert vets" could study.(See Barbara's study several posts above
this one.)<br />
<br />
It saddens me to see all these caretakers out there needing MA/feralstat
& they are being misled by the veterinarian/expert field, plus they are
paying good money for erroneous information.<br />
<br />
I wish they could all see this thread that all of us have so diligently stuck
with to help each other out with our feral colonies. Too bad we don't have a
website that could pop up in Google's first hit that could steer them all to
the great information that you all have posted here.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Yvette<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Guelph, Canada<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post238" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#238</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 14, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi Dawn: I feed stray cats at
well. Not sure if you do it already but I pick up cat poop in my immediate
neighbours lawns and that seems to keep them happy. I have a business beside
me and have even purchased a granular product that has kept cats away from
his garage.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post239" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#239</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 14, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have a question regarding flea
spot-ons. My indoor cats really hate it, and I can tell they do not feel well
for quite awhile after I put it on them. I've been researching lemongrass
extract and lemon balm extract to use as a spot-on (diluted in oil), but
there does not seem to be a consensus to its safety. That seems to be one
HUGE plus for the MA/FeralStat, it appears to kill/repel fleas. Any thoughts
on using MA for the purpose of flea prevention for my indoor cats?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p11" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #5b5b5b; font-family: "helvetica" , "sans-serif"; font-size: 16.5pt;">Tell me when this thread
is updated:<o:p></o:p></span></b></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/lancaster-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Lancaster, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post197" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#197</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Apr 24, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I have one feral
lady who can detect the ovaban in tuna from 10 feet away! Any suggestions on
how to disguise the medicine? Most will eat it if I mix it with
friskes<br />
tuna, but the most fertile one is giving me grief!!<br />
Thanks!!<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Kathryn41<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post198" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#198</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Apr 24, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Are you making it up
into a liquid first or are you crushing the pills? When diluted into the
liquid it seems to be so diluted that none of mine seem to notice it. I use
the really mushy kind of pate so I can mix it very thoroughly. Anything with
chunks and I am just concerned that it won't be thoroughly mixed and not
everyone will get that 'trace'.<br />
<br />
I mix one 20 mg pill with 4 ml water, then for my colony of 10 to 15 I use
1.5 ml of that, add another ml of water to make it more liquidy and then
squirt that over the canned food and mix it in thoroughly. That seems to
work.<br />
<br />
My missing female turned up today for the first time in 2 weeks.
Her mother didn't show up today but she was there last week and may
have come by later. The other three were here today. Time will tell if they
are pregnant or not.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post199" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#199</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Apr 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Not sure if anyone
can help but thought I would ask..I've been feeding strays at my house for
the passed 12 yrs..they have been on Feralstat & now Megestrol for 2
years so we haven't had anymore kittens..Today I recd' a violation in themail
from the town saying that i'm in violation & need to keep the cats off
my neighbors lawn..Not sure who notified the town but I don't know what to
do..I can't not feed them & i'm afraid the Humane Society will
come for them..They're like my own since some have been here for so long..Is
there anything I can do???..I think it says something about only allowing 5
cats but keeping them off others lawns..Not sure how I can do that but I have
until May 9th to think fo something..If anyone knows of something I can do
pease email me...dawnie129@yahoo.com...I was wondering what the above HOA
was..Hope someone can HELP ME<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/dallas"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post200" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#200</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Apr 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thank you! I have
been crushing pills into a powder and mixing it that way... I will make a
liquid first now! Thank you very much!<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Kathryn41 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Are you making it up into a liquid first or are you crushing
the pills? When diluted into the liquid it seems to be so diluted that none
of mine seem to notice it. I use the really mushy kind of pate so I can mix
it very thoroughly. Anything with chunks and I am just concerned that it
won't be thoroughly mixed and not everyone will get that 'trace'.<br />
I mix one 20 mg pill with 4 ml water, then for my colony of 10 to 15 I use
1.5 ml of that, add another ml of water to make it more liquidy and then
squirt that over the canned food and mix it in thoroughly. That seems to
work.<br />
My missing female turned up today for the first time in 2 weeks.
Her mother didn't show up today but she was there last week and may
have come by later. The other three were here today. Time will tell if they
are pregnant or not.<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Jan 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/raymond-sd"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Raymond, SD</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post201" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#201</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Apr 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">HI James..<br />
I posted this question to you or anyone who might know about this: about a
week or so ago.<br />
I have been feeding my "herd" of 15 cats ( only the females). since
late Jan. Then in Mar. the "wildest' one disappeared for nearly a
month..<br />
she is now back and has been since the 19th of april. My question to you , is
How long does this medicine stay in there system? I am assuming
that she is pregnant. but ofcourse won't know for another 30 some days....
Should I continue to give her the medicine,?<br />
Thanks for any help..<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post202" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#202</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Apr 29, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dawn, I feel for
you. What is the ordinance in your town regarding feeding stray animals? If
there is one, then unfortunately you may have no choice but to allow
the Humane Society to step in and try to find homes
for these kitties. How many are you feeding? Do you have the resources
to put up cat fencing to keep these cats on your property?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post203" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#203</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Apr 29, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I feed about 15
cats..7 are females & are on Birth Control..The Humane Society here
is always filled & nobody will want these outside ctas & they will
never want to be inside someones home...They're used to me only..as for
fencing there is a fence up between my yard & the neighbors but they jump
it..The main issue is them wandering in their yeard..I have never in 12 yrs
had anyone complain until this neighbor who is only here for a yr or so<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Candace<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/audubon-nj"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Audubon, NJ</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post204" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#204</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 1, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dawn, Can you go to
your town council and try to get a TNR policy instituted? I did that and even
though I have problems with one neighbor,my town has my back.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Kathryn41<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post205" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#205</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 1, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I agree with
Candace. I made a presentation to our HOA explaining what I was doing, why
TNR works and explaining about the vacuum effect if you remove the animals
from the area. I also explained about feeding contraceptive and how regular
monitoring helped to ensure the animals remained healthy and ofno
risk to people or other pets. I now have the approval of our HOA and
they have asked me to be a resource to other people in our subdivision who
are trying to cope with feral cat colonies.<br />
<br />
Put together an action plan using printed out resource material
from Alley CatAllies, from your vet and from wherever else you can find
information supporting your efforts. You may also wish to point out how much
it costs for animal control to do what they do, and how more effective both
cost and resource wise your approach is.<br />
<br />
You may wish to talk to some of your Council representatives privately - try
to find which ones own pets or cats - and get them on your side prior to
making the presentation to the Council itself.<br />
<br />
You may be able to apply for some sort of 'recognized' status that
exempts you from the ordinance and perhaps even get support for a TNR
programme in your area.<br />
<br />
Good luck.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">dawn<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/warwick-ny"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Warwick, NY</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post206" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#206</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 2, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks everyone..The
females are all on Birth Control so i'm hoping that they see that i'm trying
to keep the cat population down in my area...Will be heading to the building
dept today to see what happens..THANKS AGAIN!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p10"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">cat corner<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/milaca-mn"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Milaca, MN</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post207" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#207</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 3, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">still no luck with
the vets in this area to ok the meg or ovaban , what else would anybody
suggest, maybe somebody i could contact to get this prescription.
really need your help, tried talking to the vet but no luck,really need help
here<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/dallas"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post208" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#208</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 3, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Google CatsafratRX
then call these great people!!<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">cat corner wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">still no luck with the vets in this area to ok the meg or
ovaban , what else would anybody suggest, maybe somebody i
could contact to get this prescription. really need your help,
tried talking to the vet but no luck,really need help here<o:p></o:p></span></i></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Candace<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/audubon-nj"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Audubon, NJ</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post209" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#209</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 4, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Kathhryn, Glad you
had success with your HOA. I also found Alley Cat Allies to be
helpful. Municipalities always like the money saving aspect if nothing else.
I got their attention with that and then they understood the benefits to the
cats also. I wish they cared more about the cats than the money but I will
take what we can get!<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">cat corner<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/milaca-mn"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Milaca, MN</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post210" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#210</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">thanks Mommameow,
that did work, they are really good people there at catsafratRX, i did get
some 20 mg tablets but not real good with math . i have 14 feral cats so
exactly how much do they get a week, im thinking around a half a tablet(10
mg) per week,to mix with food ,is this correct or close, let me know Thanks<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post211" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#211</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Cat corner, 1/2 a tablet a week (10mg) for
14 cats is WAY TOO MUCH. Remember if we overdose with MA/Ovaban we are going
to end up with ferals with cancerous tumors, diabetes, etc., thus
providing feed for the naysayers of FeralStat and/or MA/Ovaban.<br />
<br />
Improper dosing & harmful effects could be detrimental to us obtaining MA
in the future, so please, please folks, let's make sure we all understand
correct dosing before dosing a colony with OvaBan. If unsure, hold off dosing
and postthe number of cats you have and strength of OvaBan tablets and
someone here should get back to you.<br />
<br />
The correct formula has been posted several times here on the previous page
or two of this thread.<br />
<br />
The CORRECT & PROPER dosage that I posted has been used by Fairchild
rescue organization for over 10 years with NO harmful results.<br />
<br />
Please, please, please folks, now that many of us are able to obtain
MA/Ovaban more easily, please be sure that you follow proper dosing and not
overdose--follow Fairchild's Org dosing and all will be fine. It takes only a
MINISCULE amount of OvaBan to treat ferals.<br />
<br />
As I stated in my previous posts, the BEST way to dose MA/Ovaban is via
liquid suspension. It is NOT hard to convert the MA/Ovaban to liquid--this
info is on the previous page of this thread.<br />
<br />
Also, ferals do NOT like the taste of crushed dry OvaBan sprinkled in their
food--it is BEST to convert it to liquid. Remember, Feralstat contained
lactose powder as a masking ingredient to mask the bad taste of the MA. Our
OvaBan tablets do NOT have these masking ingredients.<br />
<br />
I will repost the CORRECT formula here for all to look over again in the post
below this one since I am about out of "characters left" on this
one.<br />
<br />
Also, janeyjan, I do not know how long MA stays in a cat's system, but it
must not be too long since we have to dose each week....<br />
<br />
Just hope & pray that your kitty that made the short exodus is not
pregnant...feeding MA to pregnant kitties will not hurt them.<br />
<br />
For everyone here, I will post the correct dosing again below.<br />
<br />
If any of you don't understand it, by all means ask here before dosing...we
sure don't want to lose the ability to get MA, but most of all, we sure don't
want to harm the kitties because of overdosing.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/dallas"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post213" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#213</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thank you, James,
for your great information! I've tried to look up the previous posts you have
to check dosage and how to make a suspension, but my desktop computer isn't
available and my iPad has a mind of its own when I try to backtrack!!<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post216" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#216</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 11, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Catcorner, when I
first read your post I mistakenly replied that your dose was too much. That
was my mistake as I read it as 4 cats instead of 14--my mistake--my apology!<br />
<br />
Hope I didn't cause confusion--anyway, look over chart above & follow
dosages listed and all is well.<br />
<br />
I'm glad many of us are now able to get Ovaban to help the feral colonies....<br />
<br />
Best wishes to all!<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post217" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#217</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 17, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dawn:<br />
<br />
Just curious as to how your dilemma with your HOA and city council went? Are
the kitties safe ans still there?<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post218" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#218</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">May 18, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">As promised, the research I did on Megestrol
Acetate is on my website</span><a href="http://www.floridacatnews.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">www.floridacatnews.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> .<br />
From the article on the homepage, 6th paragraph, click on the
"research" link.( The sidebar links have to do with previously
posted information.)<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Kathryn41<o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara,<br />
This is excellent! Thank you so much. I am surprised at the high levels of MA
that are being used - one cat receiving per day what my entire colony of 10
to 15 (depends on who decides to show up) receives in a week! What are the
rates of pyometra occurring in a non-treated population? My friend's female
cat had kittens 3 weeks ago today. A week ago today she developed pyometra
(not metritis) and had to have an emergency spay. She has never received MA.
I understand my vet's surprise now at the low dosages we are using for our
feral populations - effective even at those low rates which work out to 1 mg
per cat per week, not the 2.5 to 5 mg per day that these studies used. It
sounds like the various organizations who have had problems with MA being
used to treat ferals are not considering the dosage levels involved in their
opposition. Anything given in large enough dosages can be problematic.<br />
<br />
Again, thank you for taking on this research. I am going to suggest my vet
come back and read the recent comments posted here again. She read this site
over when I first asked her if she would be willing to prescribe MA for my
colony at the recommended low dosages that we use so I know she will find
your work of interest.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">ouise Catmaverick<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post175" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#175</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 2, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thanks, everyone who has made a
positive contribution to understanding this issue (as opposed to the
trolls who bully and flame and obfusicate the issue at hand with
political opinions). My next question is, what is the dosage for cats using
Medroxyprogesterone. I have 2.5mg pills available. And how does it compare to
MA? I understand breeders use it off label for their cats. Thanks in advance.<br />
<br />
Louise<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post176" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#176</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 2, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Well I am glad to see that the
moderators deleted the political post a few posts above...now, back on
topic....<br />
<br />
Louise, I am not familiar with Medroxyprogesterone acetate but I did do some
googling.<br />
<br />
Try this link for more info:<br />
</span><a href="http://tinyurl.com/88y7qe2" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://tinyurl.com/88y7qe2</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
I did check out </span><a href="http://fanciers.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">fanciers.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> site and they seem to list it as 2.5 - 5 MG PER
CAT--this seems HIGH but again I am NOT familiar with that drug.<br />
<br />
I'd suggest contacting some show cat organizations and "fancy" cat
breeders who have actually used this drug for contraception in felines before
I would use it...better yet check with a "feline only" veterinarian
or one experienced in small animals only.<br />
<br />
Also, if you look at this link on </span><a href="http://fanciers.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">fanciers.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> :<br />
<br />
</span><a href="http://tinyurl.com/87w27bv" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://tinyurl.com/87w27bv</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
you will see a list of feline drugs and they list Medroxyprogesterone
in the listat 2.5 - 5mg per cat--again, I think this may be too high.<br />
<br />
Also, in this list I seriously think that they have erroneously listed
Medroxyprogesterone as a brand name of "Ovaban" along with
"Depo Provera".<br />
<br />
"Depo Provera is indeed the brand name of Medroxyprogesterone. However I
really think they have it totally wrong in that list in the link as being
brand name of OvaBan.<br />
<br />
OvaBan as we all know is megestrol acetate and is NOT Medroxyprogesterone
acetate.<br />
<br />
Again, before proceeding with any dosage of Medroxyprogesterone, I would
consult my veterinarian and/or fancy cat breeder experts.<br />
<br />
Hope this helps....<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post177" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#177</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 7, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I'll be happy to share what I
find. I'm embarrassed to say that struggling with Excel is taking as long as
the research itself.<br />
<br />
On the first chart I've got the 39 studies I found on PubMed when I searched
"Megestrol acetate cats". I'm proofing that and then will share it.<br />
<br />
Something interesting - the FDA has a "Veterinary Adverse Event
Voluntary Reporting" area which is searchable.'Megestrol" has had a
number of side effects reported, but in the 25 years the report
encompassed, there were only 3 deaths, 5 mammory neoplasms, and 14 cases
of diabetes. I tried to find the number quantity of Ovaban/Megace sold
during that time but couldn't (to try to calculate an approximate percentage
of occurance.) And there was no way of knowing if those patients had other
underlying issues.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post178" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#178</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 7, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Interesting, Barbara<br />
<br />
Is there any indication of what the dosage was for those side
effects and for how long or how many dosages were involved to create
those side effects?<o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">That's great Barbara--I commend
your research & time spent on this. I too would ilike to see what dosages
were used to cause the side effects. As already outlined by Fairchild
organization, most all side effects of MA are from
overdosing--especially the mammary neoplasms.<br />
<br />
Since Feralstat and our use of MA is very miniscule in dosage, I
confidentlyfeel we have nothing to worry about while using MAon feral
colonies. As long as we follow proper and sensible dosing, we'll have the
same safe results that Fairchild org. has had for over 10 years.<br />
<br />
Looking forward to your study Barbara--thank you again!<br />
<br />
James<o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi,<br />
<br />
One of the feral cats that my neighbor and I have done TNRed has been kind of
a house cat for my neighbor. However my neighbor can pat him but can not hold
him. The cat has been injured on one of his paw for a week and now the wound
is getting really worse. My neighbor wants to take him to see a vet but has
trouble to get him into a trap even though the cat has been inside her house
for a week. So far we are thinking to isolate the cat in a small bathroom and
use brooms to force him into a trap or cover the cat with big comforter and
wrap him quickly and put him into a trap. But we hope we can give him
something to make him feel sleepy or dizzy so he won't resist or
become very aggressive while handling him. Any suggestions would be really
appreciated.<br />
<br />
Thanks so much,<br />
<br />
Annie<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post181" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#181</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 11, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie, please describe in better
detail what type of wound "is getting worse" on the paw of the cat.
Is it a bite mark or abscess perhaps from fighting with another cat? Is it
bleeding /oozing puss? Swollen foot? Is it just a limp? Do you think the leg
is broken? Does the cat go outside periodically or is it indoors all the
time?<br />
<br />
If it is a superficial minor cut, use Betadine Scrub/Betadine solution from
WalMart--if she can pet the cat, just dab the Betadine on
a cotton ball, while petting the cat, try to get the Betadine
soaked ball on the cat's foot. Betadine is messy like iodine--be aware. If
you can't find Betadine Scrub, if all else fails, open a Betadine douche and
use the packet from that.(PS--Betadine is also great for fungus/flea allergy
wounds/ and mild cases of ringworm.)<br />
<br />
Many abscesses & wounds can best be cured well with "Vetericyn"
from Tractor Supply--a little pricey but GREAT for wounds of all
kinds--Vetericyn speeds healing by up to 60%. I've had veterinarians tell me
they even use it on themselves--I have used it myself. Vetericyn should be in
every pet owner's home pet-med supply. It comes in a spray bottle and looks
like blue Windex--try to spray a little on the foot about 2-4 times a day.
Vetericyn is safe to use and doesn't hurt eyes if you accidentally spray it
in cat's eyes...<br />
<br />
Of course, all of my recommendations depends on the severity of the wound and
what type it is.<br />
<br />
How did the cat get hurt?<br />
<br />
If it's just a limp, nothing puts fear in the mind of a pet owner more so
than a limp! "OMG! Fluffy is limping! Call the vet!"<br />
<br />
MOST limps cure themselves in a few days...again, use common sense to
diagnose the wound/limp etc..if the wound is bad enough that you think it
needs vet care, then by all means proceed to try to trap the cat & get it
professional help.<br />
<br />
As for tranquilizing the cat--don't do it and don't try it. Best to put on
gloves, corner the cat in a small bathroom, use a comforter, pillow case, big
towel, whatever and have pet taxi ready with door open to put kitty in..be
prepared for battle scars...<br />
<br />
Please report back on the type of wound to the paw--is it possible to get
apicture of the wound?<br />
<br />
I'll post back when I hear from you here...<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post182" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#182</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 11, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James,<br />
<br />
Thanks so much for your quick response, help and very useful tips.<br />
Since I did not see the wound myself, I have asked my neighbor to provide any
details.<br />
I honestly hope either Betadine Scrub/Betadine solution or Vetericyn would
help the cat get over the wound.<br />
<br />
Thanks again,<br />
<br />
Annie<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post183" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#183</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 16, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I was able to get 100 40-mg
megestrol AC for $52.99 from this site:</span><a href="http://drugstore.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">DRUGSTORE.COM</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> . I listed the patient as Cat Colony (plus my name)
and indicated the use was for feral feline contraception. I provided my vet's
name and phone number, and they called him and he approved the
request.<br />
<br />
James, would you please verify for me that I am reading your recipe
correctly and my math is correct. I will take this 40-mg pill, dilute it in 8
mL of distilled water so that I have 5 mg/mL of MA. I take it the goal to get
each cat to ingest 0.1 mL (0.5 mg) weekly; hence 1 mL would dose 10 cats, 8 mL
would dose 80 cats. Since I have on average 20 feral cats 1 pill should last
4 weeks at 2 mL per week.(Thanks in advance for your time, James.)<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post184" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#184</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 16, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen, you do indeed dilute ONE 40
mg MA pill in 8 ml of water. Look back at my post above and you see that
Fairchild recommends the following dosage for a COLONY of 20-23 cats is 1.6
ML TWICE A WEEK.<br />
<br />
This 1.6 ML of the liquid suspension is PER COLONY, not per cat. Since the
dose is twice a week for that number in a colony, then you will be using 3.2
ML of the liquid solution once a week, thus ONE 40 MG pill in solution will
yield you 2 & 1/2 weeks of dosing (3.2ML + 3.2ML + 1.6ML = 8 ML)--again
this is dosing the entire colony of 20 cats at 1.6 ml TWICE a week.<br />
<br />
Remember to spread the twice a week dosage (1.6ML) evenly among the canned
food you are feeding them....the 20 cats in your colony thus will be
ingesting very small amounts of the MA twice a week--the small amounts per
cat is what makes the use of MA so safe--problems arise from OVERDOSAGE.<br />
<br />
Overdosage of MA is what the naysayers of Feralstat/MA/Ovaban are concerned
about.<br />
<br />
Hope this clears things up.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post185" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#185</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 20, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thank you James! Can you answer
another question -- I never had to dose the FeralStat twice in a week -- why
is the MA different? A "bonus" I have noticed with the FeralStat is
those cats do not have fleas! Lice, yes, but not 1 flea. I dosed the MA for
the first time this past weekend, and for 20 cats I used two 13-oz cans moist
food, to which I added 2 teaspoons of "Better Than Bouillon"
chicken base (because the MA is bitter)-- the cats gobbled it down, which
they never did with the FeralStat; they would eat the food with FeralStat,
but not gobble like they did this past weekend. I am sooooooo relieved to
have them back on contraceptive ... hope it wasn't too late and we still end
up with spring kittens.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post186" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#186</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 20, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen, I am not sure why </span><a href="http://fairchild.org/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">Fairchild.org</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> recommends
the twice a week dosage of the MA, I am merely posting what Fairchild's tried
& proven record is. I am guessing that we could get by with once a week,
but then again I am not sure.<br />
<br />
That is a good question we should though--we should email Fairchild and ask
them why they recommend the twice a week dosage & Feralstat was only once
a week.<br />
<br />
It's great that you have a flea free colony.<br />
<br />
I'm glad you have worked out a palatable recipe for the kitties as well with
the bouillon.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post188" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#188</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 26, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I logged onto this site today from
my work PC--in fact I tried 3 computers and all 3 of them are not showing my
previous post above in which I cleared up the "dosage mystery" as
to why Feralstat was once a week and Fairchild recommends twice a week for
larger colonies.<br />
<br />
Can someone post here if they can indeed see my post just above this one
dated March 20, and it starts out like this: "OK...dosage mystery
solved."?<br />
<br />
I myself can see that post of mine on my home PC but as I stated, on three
other computers that post is not showing up.<br />
<br />
If you can indeed see that particular post, please post a reply here.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post189" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#189</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 30, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James, I do not see your post
regarding the "dosage mystery," but would really like to know the
answer. My guess: If it's dosed twice in larger colonies it will be more
evenly distributed and hopefully if a cat misses one dose it will get the
other.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">cat corner<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/milaca-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milaca, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post191" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#191</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">cant seem to find a vet that would
help me with the matter of MA, is there anybody with a idea or knows of
somebody that could help in this matter, let me know, been keeping up with
this blog and need some advice<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post192" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#192</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Cat Corner, try placing your order
first, list your vets name and number, and see what happens. I was able to
get 100 40-mg megestrol AC for $52.99 from this site: </span><a href="http://drugstore.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">DRUGSTORE.COM</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> .
I listed the patient as Cat Colony (plus my name) and indicated the use was
for feral feline contraception. I provided my vet's name and phone number,
and they called him and he approved the request.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post193" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#193</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">It seems that Topix keeps deleting
the post about why Feralstat was dosed once & MA is dosed twice, so I
will condense what I learned as to why we dose larger colonies with MA TWICE
a week--it is indeed so that we are assured that ALL the cats (female) get
the dosage--if you sure that all females get the med during feeding, then you
can safely do it only once a week like the original Feralstat.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/dallas"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post194" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#194</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 6, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Google CatsafratRX then call these
great people, cat corner!<br />
<br />
This forum has helped me so much! While searching for a FeralStat replacement
I have had 8 feral kittens born, but I have homes lined up for several of
them and I am hoping that Ovaban will help me once again stop the cycle!<br />
<br />
They don't like the flavor of the crushed pills - even in tuna - but we're
working on it....<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/janeyjan" title="See janeyjan's profile"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.5pt;">janeyjan</span></b></a><b><span style="font-family: "times new roman" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Jan 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/raymond-sd"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Raymond, SD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post195" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#195</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi James,<br />
I have run into a bit of a problem, with one of my cats. I have been feeding
14 females since the latter part of Janurary, and then on March 14th
"the wild one", just left, home, and did not show up until the 19th
of April. That is about a month with out any birth control...YIKES!!!<br />
My question to you is this" How long does this ferlastat or ovaban, stay
in there system?<br />
--- I don't know if she has gotten bred, so can I just start giving her the
"pill" lol, once again? What happens if she is bred? Would this
cause her to loose any kittens that she might have ?<br />
I sure am hoping someone can give me some insight on this? Thanks for any
help here..<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn41<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/jonesboro-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Jonesboro, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post196" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#196</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I have had a similar problem.
Someone started disturbing the site where I feed my ferals even though it is
signed with the authority of my HOA. Two weeks ago none of the cats showed up
for the date. I re-dosed 2 days later and know that one of my 5 females did
get it but didn't see the other 4. Last week, again, none of the femals
showed up. Only 3 of the males have been showing up semi-regularly until two
days ago where 4 of the females are showing up - very nervous and skittish
about the site so I know someone or something has disturbed them there.
Tomorrow I will dose again and hope that all of them show up but there
appears to be a two week period where 4 of them probably did not get their
medication. I am curious as well how long the ovaban will stay in the system
and hope there might be some overlap.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p9"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-79270659101063979292018-07-01T20:19:00.000-07:002018-07-20T14:20:05.146-07:00Topix thread 06152015 posts 221 to 290<table border="0" cellpadding="0" class="MsoNormalTable" style="mso-cellspacing: 1.5pt; mso-yfti-tbllook: 1184; width: 640px;">
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post290" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#290</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">How about "NoMoreFeralKittens DOT
com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post291" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#291</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James - if your target audience is people
outside of the TNR /rescue world, I wouldn't use "feral" in the
domain name since 90% of people either don't know the term or have a negative
association with it.<br />
<br />
FYI, after a post I read on another blog about the FDA being responsible for
Feralstat being off the market I searched the FDA website, both regular
and veterinary drugs and recalls,voluntary withdrawals, and safety alerts and
there was nothing at all for "Feralstat".<br />
<br />
I also read through the FDA guidelines for veterinarians as far as
prescribing human drugs to animals, and they're given pretty wide
latitude.<br />
<br />
As far as the trademark, John Caltabiano is listed as
"registrant" but I didn't check to see how the registrant passing
away affects the trademark status.<br />
<br />
My two cents - after advocating for humane treatment of feral cats here in
Florida for years and coming up against a few well connected cat haters whose
life goal seems to be keeping catch-and-kill the method of choice for
"controlling" feral cats through animal control, it doesn't
surprise me when anyone walks away from public endorsement of TNR/feral birth
control. These people are vicious and tireless.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post292" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#292</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barabara, you are
right about the majority of the public not knowing what the word
"feral" means.<br />
After I made my post above about the domain having the word
"feralstat" in theDOT com site, I began to wonder about myself
about trademark infringement...probably best the word "feralstat"
be left out of the domain name.<br />
<br />
I too have run up against the cat-haters and know exactly what you mean about
that.<br />
<br />
I myself too do not think that Feralstat was pulled because of FDA...if it
had been, there would be record of it on the web somewhere. The ones that
keep saying the FDA pulled Feralstat can't ever offer one shred of evidence
to support that. Even some veterinarians erroneously report this as well, a
perfect example was the post I posted here a few months ago about those vets
that are on the payroll at one of those askDOTcom websites where a person
asks a question and then pays the vet online when they answer it--lots &
lots of erroneous information being "sold" to customers by these
online vets when they ask about Feralstat. Not a single one of them ever
quote this Topix thread or offer alternatives to their customers when asking
about alternatives to Feralstat.<br />
<br />
I think if there was a simple website setup with a condensed
version of what we all have found out here on our own about a safe
alternative to Feralstat, more & more unwanted litters would be
prevented, plus the public and vets themselves would be more educated about
feline contraception.<br />
<br />
My friend has offered to set up a simple website for this purpose
and I will supply him with the condensed & correct methods/info of mixing
and dosing the MA, thus the public would not have to wade thru this now 2-yr
old Topix thread for info on Feralstat alternatives.<br />
<br />
Last weekend, I visited a large business and the employees there had
"adopted" a small colony of feral cats on the premises..all
employees feed them daily and they are trying their best to TNR the colony,
but they can't get ahead of the game. I told them about MA and this
thread...they are now in process of buying MA and mixing themselves until
they can TNR the whole colony. The employees had no idea a feline
contraceptive existed and neither did their vet (supposedly).<br />
<br />
Keep suggesting domain names folks....I'll keep you posted..<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post293" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#293</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I think the
site is a great idea. Anything that can be done should be done to spread
the word that we finally have an edible birth control for cats. Especially
since it looks as if this is going to have to be a grassroots movement since
the large groups can't/won't endorse it.<br />
<br />
If you need it, I copied all but the last couple posts from this thread that
discussed dosage and where to get MA in to a Word doc.<br />
<br />
As far as a name - what about catbirthcontrol dot com.<br />
<br />
Barbara<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<v:f eqn="prod @3 21600 pixelWidth"/>
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<v:f eqn="prod @6 1 2"/>
<v:f eqn="prod @7 21600 pixelWidth"/>
<v:f eqn="sum @8 21600 0"/>
<v:f eqn="prod @7 21600 pixelHeight"/>
<v:f eqn="sum @10 21600 0"/>
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<v:path o:extrusionok="f" gradientshapeok="t" o:connecttype="rect"/>
<o:lock v:ext="edit" aspectratio="t"/>
</v:shapetype><v:shape id="Picture_x0020_19" o:spid="_x0000_i1031" type="#_x0000_t75"
alt="http://static.topixcdn.com/pics/blank.gif" style='width:15pt;height:15pt;
visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image001.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image002.png" v:shapes="Picture_x0020_19" width="20" /><!--[endif]--></span><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
id="Picture_x0020_20" o:spid="_x0000_i1030" type="#_x0000_t75" alt="http://static.topixcdn.com/pics/blank.gif"
style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image001.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image002.png" v:shapes="Picture_x0020_20" width="20" /><!--[endif]--></span><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post294" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#294</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">What about:<br />
<br />
BirthControlForCats DOT com ?<br />
<br />
Easy to remember and spell...<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
id="Picture_x0020_21" o:spid="_x0000_i1029" type="#_x0000_t75" alt="http://static.topixcdn.com/pics/blank.gif"
style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image001.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image002.png" v:shapes="Picture_x0020_21" width="20" /><!--[endif]--></span><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">BusyBee<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/monroe-ga"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Monroe, GA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post295" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#295</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">What about:<br />
BirthControlForCats DOT com ?<br />
Easy to remember and spell...<br />
James<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I like your idea and
also "Barbara in Orlando" suggestion of CatBirthControl dot
com<br />
BirthControl4Cats dot com (yours in another way :)<br />
<br />
Did you get my email, James?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post296" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#296</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Busy Bee, I like
your suggestion as well. Yes, I did get your email...you should have received
a reply by now..if not, email me back & I will resend it.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post297" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#297</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando:
Another good suggestion you have there for a domain name...I may just see if
my friend will register two names and point the DNS settings to one
site, that way we can be covered with two easy to remember names...after a
few more suggestions for domain names, then maybe we can all decide and I'll
send the domain names to my friend and let him register itwith domain
services and then he can work on getting a web site up &
running.<br />
<br />
The MS Word document would be great to have with all the
dosages listed. I can PDF it with Acrobat Pro X and people
visiting the site would have access to a PDF as well
as MS Word documents.<br />
<br />
Last night while researching more on megestrol acetate for feline
contraception, I ran across some foreign websites that referred to a drug
known as "Megecat"...turns out this is a feline contraceptive
prescribed by vets in other countries such as Belgium, Switzerland, etc. I
haven't researched much more on the dosages, but it seems like it has been
used for some time in other countries. I wonder why so many vets here in USA
are unaware of MA in felines for contraception?? Hmm...just strengthens my
hypothesis that there is too much $$$ involved in feline contraception here
in the USA and the drug companies can't patent MA, thus we have to wait years
& years for ACCD and FDA and drug companies to bring AFFORDABLE
contraceptives for cats and dogs to market, if they ever do.<br />
<br />
Barbara, you hit the nail on the head when you said this is turning into a
grassroots effort. I'm glad we all stuck with this for the sake of the
kitties as well as the caretakers.<br />
<br />
I'm sure when the website goes up there will be all the naysayers and hate
mail coming in from all over...I'm sure it will be bombarded...I know that is
a "given"...I'm just surprised this thread itself has stayed so
"clean" and not hijacked by the naysayers.<br />
<br />
When I read your post Barbara, it reminded me of this quote: "Never
doubt that a small group of thoughtful, committed citizens can change the
world; indeed it's the only thing that ever has." -Margaret Mead<br />
<br />
I'll keep you all posted on progress of the website as other suggestions come
in.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">JKPC<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/la-quinta-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">La Quinta, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post298" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#298</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Where can I get
megestrol acetate/feralstat or ovaban?<br />
Do I have to involve a vet?(Not likely here.)<br />
The neighborhood is being over run by ferals. It is not feasible or
affordable to trap & neuter all of the cats. Esp. with no help from neighbors
or rescue groups. THANKS for any information you can provide.<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Oct 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post299" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#299</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">You can google to
find megestrol acetate on non-prescription foreign sites. Any MA strength
will do. You would just have to break it down for the dosing protocol you
choose. I've seen 2 so far, but have not read the entire site right here. Because
only small amounts would be ordered, the product comes into the country
relatively smoothly. What we would use for cats is not enough to make customs
think we are setting up a resale operation.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post300" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#300</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James - I emailed
you the Word doc. with the MA dosage discussions from this forum - please let
me know if you don't get it. Sorry about the delay - for some reason I don't
get all notifications of new postings and just got one today.<br />
<br />
As far as Megecat, that's interesting and not surprising. When I was
searching PubMed for MA studies I noticed that vets outside the US often
offered the full text of their studies for free on-line where very few if any
studies from US vets were available in full. It's all very discouraging.<br />
<br />
Thanks for the inspirational quote.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post301" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#301</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I got it Barbara...I
have replied via email to you.<br />
Thank you so much!<br />
<br />
Website will be up soon--may just be after Christmas though.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Debbie<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post302" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#302</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">So where can this
product be purchased. I have several kittens this year. More than last year.
ANd I would love to help keep this from happening. Too many cats that aren't
wanted.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Debbie in Texas<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post303" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#303</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I would love to find
this product or anything like it. Any help anyone can give would be greatly
appreciated.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post304" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#304</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Did you read posting
# 260 ? Excellent info. about approaching a vet about prescribing MA. My
first request was a "no" (and he charged me for the visit) but that
was a learning experience and I'll keep trying.<br />
<br />
#269 and #299 mention ordering from foreign sources.<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">JKPC wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Where can I get megestrol acetate/feralstat or ovaban?<br />
Do I have to involve a vet?(Not likely here.)<br />
The neighborhood is being over run by ferals. It is not feasible or
affordable to trap & neuter all of the cats. Esp. with no help from
neighbors or rescue groups. THANKS for any information you can provide.<o:p></o:p></span></i></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">steveh<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/hudson-ma"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Hudson, MA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post305" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#305</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara, Did the
money grubbing bastard even give you a reason why. You should have told him
to put his/her bill "where the sun don't shine"!!!! Please post his
name & address - I'll be glad to contact him & it won't be to wish
him/her a Merry Christmas. Good luck in finding a vet willing to write you a
perscription - they're out there so don't give up. Steve<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/jkpc" title="See JKPC's profile"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;">JKPC</span></b></a><b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Dec 12<o:p></o:p></span></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">SoCAL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post306" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#306</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks for your
responses to my inquiry!<br />
I have a the head of feral rescue group (affiliated with a local shelter
which the group influenced to become a no-kill) coming tomorrow to do a mass
trapping for TNR.<br />
I met with her today when she delivered a new large group trap & asked
why they weren't using "the pill for cats". She was unaware of
MA/Feralstat and asked why it wasn't mainstream. I said I imagined it had to
do with FDA. She also expressed concerns about side affects. I said if we
woman can use a pill why can't cats? How bad would it be for a male to get a
low dose?(We LOL about that & agreed the world might be a more peaceful
place - no offense to you guys intended, really).<br />
After cries for help to many rescue groups over several years, I was directed
to this local group as they are affiliated in their TNR program with Best
Friends in Kanab, UT. Being new to this thread, there is lots of reading to
get to the important facts.<br />
Would one of you who has participated in this thread over the years please
post the important facts in summary form so I can print and give to this
woman? She is a successful, high profile business woman here in SoCA & is
committed to improving the quality of life for "community"/feral
cats and she has contacts with Best Friends. She possibly could be a
tremendous help to the kitty birth control movement.<br />
THANK YOU!<o:p></o:p></span></div>
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<span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">There are </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12#comments-link-target"><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 11.5pt;">332 comments</span></a><span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;"> on the </span><a href="http://catsinthenews.blogspot.com/2008/07/feralstat-contraceptive-accd-statement.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Feral Cats in the News</span></a><span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;"> story from Jul 29, 2008, titled <i>FeralStat
contraceptive: ACCD statement</i>. In it, Feral Cats in the News reports that:<o:p></o:p></span></div>
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<span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Thursday, July 24,
2008 FeralStat contraceptive: ACCD statement AnimalResources early requested a
statement about FeralStat from leading feral cat and nonsurgical sterilization
veterinarians and the Alliance ...<o:p></o:p></span></div>
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<span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Join the discussion below, or </span><a href="http://catsinthenews.blogspot.com/2008/07/feralstat-contraceptive-accd-statement.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Read more</span><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 11.5pt; text-decoration: none;"> </span></a><span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">at Feral Cats in the News.<o:p></o:p></span></div>
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<b><span style="color: #898989; font-family: "roboto" , "serif"; font-size: 10.5pt;">221 - 240</span></b><span style="color: #898989; font-family: "roboto" , "serif"; font-size: 10.5pt;"> of 332 Comments Last updated <b>Thursday
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<span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"> </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p13"><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;">Next</span><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt; text-decoration: none;"> </span></a><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"> </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p17"><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;">Last</span><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt; text-decoration: none;"> </span></a><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post240" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#240</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 14, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James, I somehow stumbled upon
this site via Google.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post241" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#241</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 15, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen, what brands of spot-on have
you tried on your kitties? There are cheap ones & expensive ones, made by
companies such as Hartz, Seargents, Frontline (Merial), Advantage (Bayer),
Zodiac, Bio-Spot, etc. They all contain different or similar active
ingredients. Like humans reacting to medicinesdifferently, some cats
react to these topicals different too. In plain terms, these are all topical
insecticides, with the exception of Revolution, which is a drug (selamectin)
& must be obtained by a vet RX.<br />
All others are available OTC & sold in every store from dollar stores to
grocery stores.<br />
<br />
I myself prefer Frontline Plus & Advantage. I've never found MA to be a
flea killer or repellant, & I gave up on herbal
flea remedies years ago because they just didn't seem to work on my
kitties.<br />
<br />
Rather than doctoring the cats directly with topicals, you may have
much better luck doctoring the cat's habitat--your yard, home,
pet bedding etc with the same type insecticides found in Frontline
or Advantage. If you are interested in this method, let me know & I can
tell you what chemicals you can use DIY in your yard & home that mimic
Frontline or Advantage and best of all, cost a LOT less than a dose of
either.<br />
<br />
Please post what spot-on you tried that bothered your kitties & we'll go
from there...<br />
But again,I've never seen any evidence that MA was effective on fleas &
ticks.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post242" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#242</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 17, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James, I use BioSpot at half the
dose as directed. We do use yard/foundation spray for fleas, and use Enforcer
to spray their bedding and mop boards/molding along the floor, rugs
at entrances into the house.<br />
<br />
The reason I believe MA is a flea killer/repellant: Last summer, at the farm
where we feed the barn cats/ferals, they have 3 housecats and 2 dogs and they
had a horrible outbreak of fleas in their house pets. I've never seen so many
fleas on an animal. When I dipped their cats the water turned to blood from
all the flea poop on them. The barns cat/ferals had ALWAYS had fleas and lice
(the 2 cats that we are able to handle we would dip in the summertime). This
past summer, when their house pets got infested so horribly, of course they
blamed the barn animals. The 2 that we are able to handle we dipped and there
was not 1 flea on them, many lice but not 1 flea. It had to be the MA.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post243" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#243</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 19, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen, that has me stumped---can't
figure out why the ferals would not have fleas as I've never heard of MA
being a repellant, but I guess it is possible.<br />
I'll do some more research and let you know.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Anonymous<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post244" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#244</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 19, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Can someone give me a name &
number of a vet that would not care if I used it to get MA. I just got rid of
the last bunch of kittens that happened after the feralstat was taken off the
market. I don't want that to happen again. It happened so fast I didn't have
time to get anything. I cannot find a vet. I was really luckey to find home
for the kittens, there were seven of them. I just can't afford to feed that
many more.I had talked to Jamie or Jannie before all this happened. Ginger<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post245" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#245</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 21, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ginger, email me off list at the
email addy below, substituting "@" & "." for the
words:<br />
<br />
</span><a href="http://ftaboxeratyahoodot.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">ftaboxerATyahooDOT.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Anonymous<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cumberland-md"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Cumberland, MD</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post246" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#246</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 21, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I am so sorry but it won't work.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post247" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#247</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 21, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ginger, just send an email to
ftaboxer and place the @ symbol after the word boxer instead of the word AT,
then the suffix is standard yahooDOTcom<br />
<br />
Just substitute a . for the word DOT and all is fine.<br />
<br />
ftaboxerATyahooDOTcom<br />
<br />
I don't understand what you mean when you say it won't work--does the email
bounce? If so, then you aren't spelling it properly--just follow standard
email address protocol and all is fine.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/albuquerque"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Albuquerque, NM</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post248" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#248</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Has anyone ever thought about
going to </span><a href="http://change.org/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">change.org</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> and
starting a petition to get FeralStat back on the market?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post249" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#249</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen and James - your discussion
about fleas is so timely - I'm having a hell of a time with my cats and dog.
Having to re-dose the dog after a week sometimes with the
Advantage. Ironically, the one cat that insists on being outside 100% of the
time doesn't seem to be that plagued by fleas - maybe it's not the MA but
some kind of a natural immunity they develop ?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post250" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#250</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 23, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara, I too have wondered if
feral cats/colonies evolve to develop a natural immunity to fleas. I have
seen colonies in the past that would not be flea-ridden, but like you, my 3
domestic indoor house cats would have a terrible time with them.<br />
<br />
Fleas are bad this year, but so far I have nipped them in the bud with my
prevention methods both indoors & outdoors.<br />
<br />
I treated my entire yard with imidacloprid, the same active
ingredient in Advantage, doing it this way is much cheaper than buying
Advantage for the pets.<br />
<br />
Have also treated my yard and the feral colony's uptown alley area with it as
well. In the past I have also used a fipronil based spray (same ingredient as
in Frontline) since I could not directly dose the ferals with Frontline or
Advantage.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/milwaukee"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Milwaukee, WI</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post251" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#251</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 27, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara and James, regarding fleas
-- I'm still leaning toward the MA because prior to its use any barn cat that
we were able to handle we dipped because they were soooo flea/lice-ridden.
The lice are still a big problem in the barn, but not fleas. We have been
feeding the barn cats, along with their feral friends, for 15+ years. I am
thinking it takes a full year of MA use to see the benefit against the flea.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post252" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#252</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 27, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Karen - that's really amazing.
Thanks for sharing. One more reason MA needs to be in canned food in every
Petsmart.(I can dream, can't I ?)<br />
<br />
James - I'm kind of caught because I'm in a condo complex where they don't
treat the dog walk for fleas. I've considered doing it myself under
dark of night - do you know if there's anything in imidacloprid that would be
harmful to animals if one wandered through just after treatment ?<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post253" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#253</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 27, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara, imidacloprid is the
same active ingredient found in Advantage topical spot-ons for
fleas in dogs and cats. Advantage contains 9.1% imidacloprid.<br />
<br />
The "old" Advantage was only adulticidal and did not kill flea
larvae and eggs, unlike Frontline which contains fipronil and (S) methoprene
which targets larvicidal and ovicidal stages of the fleas--larvae & eggs
respectively.<br />
<br />
The fipronil in Frontline kills fleas, and the (S) methoprene kills the
larvae & eggs.(S) methoprene is an "IGR" (insect
growth regulator).<br />
<br />
The Bayer company that markets Advantage, in a move to catch up with Merial
that markets Frontline, came up with "Advantage II" for dogs and
cats. The "new" Advantage II contains imdacloprid and
Pyriproxyfen--the pyriproxyfen is a new "IGR" to kill flea larvae
and eggs.<br />
<br />
Again, the amount of imidacloprid in each vial of Advantage (new & II) is
9.1%.<br />
<br />
To make a yard spray to mimic Advantage without actually doctoring the cat or
dogs, you can make up your own solution of "generic" Advantage--a
yard spray sort of.<br />
<br />
The Bayer company holds the patent on imidacloprid. They also allow other
pest control products to use imidacloprid in their formulations.<br />
<br />
Bayer makes a fly spray for barns & stables called "QuickBayt"
which contains 10% imidacloprid, slightly higher than the 9.1% imidacloproid
found in Advantage old & II.<br />
<br />
You can buy QuickBayt at a large feed store--about $11 for a bottle. The
bottle is a spray type bottle (like what Windex comes in). The QuickBayt
bottle contains only the dry powder mix of imidacloprid as well as a sugar
attractant for flies (0.1% tricosene).<br />
<br />
You buy the QuickBayt bottle of powder and fill it up with water to make a
fly spray for barns and stables.<br />
<br />
What you want to do is buy a bottle of QuickBayt and pour the powder into a
small 1 or 2 gallon pump-up sprayer and then fill with water. You now have
effectively mixed a diluted form of Advantage with imidacloprid as
the active ingredient.<br />
<br />
Now just pump up the sprayer and spray your yard, dog run, or whatever with
the fly spray mixture.<br />
<br />
Again, remember that imidacloprid only kills the adult fleas--not the larvae
& eggs. If you want to go one step further and mimic the larvicidal and
ovicidal effects of Advantage II, then you can buy a small bottle of
"Precor", which is an IGR to kill flea eggs and larvae.<br />
<br />
A small bottle of Precor IGR is also available at feed stores as well and is
sold as a DIY pest control product to be added to flea sprays for home and
yard.<br />
<br />
A small bottle of Precor IGR will run you about $10 as well. Mix the Precor
with the QuickBayt in the pump sprayer and spray the target area. The
imidacloprid is residual and will kill adult fleas for weeks and weeks--the
Precor will kill the eggs & larvae.<br />
<br />
A $20 investment in QuickBayt & Precor & mixed in a pump up sprayer
goes a LOT further than a $40.00 pack of Advantage that contain only a few
CCs of product.<br />
<br />
Again, just spray the area the dogs & cats run in and all is fine. The
QuickBayt is made for barns & animal quarters so it is safe around
animals.<br />
<br />
You could do a stealth spraying of the dog run in your condo at night and the
area will be flea-free for weeks and weeks...plus flies will eliminated as
well since QuickBayt is marketed as a fly insecticide.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Penny<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/east-liverpool-oh"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">East Liverpool, OH</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post254" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#254</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 30, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I had been using feral stat on my
feral colonies...till i could not longer get it. What a pity...now i am
having to deal with litters of kittens. Feral stat worked. I cannot trap all
these cats ...some were caught...some were too smart to trap. Now i am feeding
even more cats/kittens with no end in sight. These cats have no home and no
one wants them. I am willing to take the risk of feral stat...there are just
toooooo many for me to deal with.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Bert<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/dalton-ne"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Dalton, NE</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post255" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#255</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 30, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I've been rescuing cats (and some
dogs) for over 10 years. I am now broke because of it.<br />
<br />
First, regarding FeralStat: I find it hard to understand the so-called
concern for potential side effects of the product. Are they really worse than
the "side effects" of overpopulation? FeralStat was making it
possible for one person to manage ferals affordably, whereas
trap-neuter-return is labor intensive, very costly, and no assurance of
catching every individual. So it's better to let them multiply to
overcrowding, leading to starvation, fighting, disease, and wholesale death?
What makes anyone think they would live longer under those conditions anyway?
Shame on the veterinary medical industry for forcing suffering under terrible
conditions when another option exists. And here's a wake-up: amazingly, not
all veterinarians care. In our rural area, vets are livestock oriented. Cats
are just a bother. Dogs are less so, as long as they are "cattle
dogs." I've had no success in implementng any spay/neuter programs. Oh,
I can bring them in for the surgery, and I have (they do not object to the
extra income!), but then animal control runs routine trap-and-kill sessions
anyway, not to mention what the farmers do. I've rescued many that were
injured from a bad aim, legs caught in steel jaw traps, or just plain
skinny/hungry and pest-infested. If the colonies could be limited, perhaps
all these people wouldn't get so worked up about culling.<br />
<br />
Second issue: fleas, etc. Speaking of side effects and over-chemicalizing our
animals, there are natural options that are no more expensive than the
consumer products. I refer you to </span><a href="http://www.cedarcidestore.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">www.cedarcidestore.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> .
I just started using the product called Best Yet in a spray bottle. One quart
for $30. It smells bad, but it keeps the flies off my dogs' ears, kills adult
fleas, ticks, ear mites, and any other 6- or 8-legged pest. This stuff is so
safe, you could get it on your food and it wouldn't hurt you. Yuck, but
hey... you can use it wherever you're having a picnic or BBQ and everyone
will be fine, including the kids. Take it camping or boating...use it on
yourself, not just the pets. And no, I don't get a commission for mentioning
them. They don't even have an affiliate program. But you can buy a
"portable store" from them and carry it around selling the stuff.
Like I have time...<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">linda<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/yucaipa-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Yucaipa, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post256" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#256</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 17, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I am ordering from the link you
provided for megestrol acetate. Now, I need to know how much and how often to
sprinkle of food. About 8 feral cats in colony.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post257" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#257</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 17, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Linda, the information you ask has
been covered in this thread thoroughly just a few posts back. Please, please
before anyone starts dosing colonies with MA, be sure you understand the
correct dosage and how to mix it. The best way as we have all said is by
making a liquid suspension out of two pills.<br />
<br />
Out of respect for everyone here that has stuck with this thread and put so
much time and effort here working out dosings and researching side effects,
please go back and read the posts that so many have researched here. Then if
you do not understand the dosing, then we all will be glad to help.<br />
<br />
Again, the information you seek is just a few posts back. I have posted the
dosage charts & frequency several times in the past few weeks. The
information is also posted on </span><a href="http://fairchildcat.org/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">Fairchildcat.org</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> as well.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">yerlo<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post258" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#258</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 16, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">julie wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">It's Sept 8, 2011. I
have one week of Feral Stat left and I have 60 cats on it. Can you imagine
what can happen with that many once it is used up? I must find out what's
going on, so is there any updates?<br />
Also, when folks talk about side effects....read carefully, there are none to
speak of. It states these things can happen in LARGE doses. Also, how does
one supposed "expert" really know. Heck, vet "experts" do
not even know about the miracle cure apple cider vinegar for cats and even
newborn kittens.<br />
I have used Feral Stat since 2009 with no problems and no kittens.
jaws6418@gmail.com<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">What is that apple cider miracle
cure? What does it cure and how is it used?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post259" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#259</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 7, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Kathryn41 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">I would think that
most colonies wouldn't have a problem with left over medicated food. The
amount given is so small that you try to concentrate it enough in the wet
food that then gets eaten up.<br />
My colony gets medicated food on Tuesday mornings between 6:30 and 7 am. I
use one large can of catfood to mix in the megestrol. There are 11 serving
dishes for food. I put their dry food down first then each dish gets a glop
(about a tablespoon) of medicated food on top. The cats start to eat the
medicated food right away and finish that before they eat the dry food. I
take note of who is there and eating and watch to make sure all of them
actually do eat. They run around from dish to dish, alert and on guard to any
movement outside of the area. Once I see that all have eaten some medicated
food I leave them to finish. I go back around lunch time to 'check'. There
may be some dried food left but there is never any of the medicated food
left. There wouldn't be any wildlife around during the day that would get to
any medicated food that is left out. There are opossums, raccoons,fox, coyote
and birds in the area. I do know that the birds sometimes finish up any dry
food that is left but the mammals don't come out during the day so I think
with careful management it is unlikely that wildlife would get any of the
food. The only problem I might have is if a neighbourhood dog gets loose -
they aren't allowed to be loose here - and accidentally stumbles on the
dishes before the cats finish them. It hasn't happened yet but I guess it is
always a possibility.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Kathryn41~I live near Atlanta GA,
can you tell me where you get your cat birth control.<br />
Thanks.<o:p></o:p></span></div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-36023205681378694092018-07-01T19:49:00.000-07:002018-07-20T14:18:15.797-07:00Topix thread 06152015 posts 291 to 354<div class="MsoNormal" style="background: white; line-height: 37.5pt; margin-bottom: .0001pt; margin-bottom: 0in;">
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<a href="file:///C:/forum/city/kirkland-wa"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Kirkland, WA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post354" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#354</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 19, 2014</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Sorry to address you as Dean,
James. Regards~Louise<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Trish<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/phoenix"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Phoenix, AZ</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post355" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#355</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 20, 2014</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Just placed an order a few days
ago for the Nonovulin...am hoping to get it soon. Have one mama cat I have
been unable to trap for a year! She's wily. Can anyone who has recently tried
it give me some feedback? Just curious to see how it's going for you. I only
have 2-4 cats (that I know of) that I am feeding, and almost all are fixed at
this point, except for the wily mama, and one of her kittens, and the odd
stray that comes by here and there.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post356" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#356</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 23, 2014</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Just a note to say that as of
Friday 6/24/2014, I will be allowing the</span><a href="http://floridcatnews.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">floridcatnews.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> site
to expire. I am in the process of moving all the information to </span><a href="http://floridacatnews.blogspot.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">floridacatnews.blogspot.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> .<br />
<br />
Also wanted to say that I had a problem with Nonovulin getting moldy after a
week when I mixed it with water, so I emailed the seller who recommended that
it not be mixed with water - I began using a pill crusher and mixing the
particles in with the wet food, just crushing enough each week for that
week's dose.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Trish<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/phoenix"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Phoenix, AZ</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post357" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#357</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 24, 2014</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Barbara in Orlando wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Just a note to say
that as of Friday 6/24/2014, I will be allowing the </span></i><a href="http://floridcatnews.com/" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">floridcatnews.com</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">site to expire. I am in the process of moving all the
information to</span></i><a href="http://floridacatnews.blogspot.com/" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">floridacatnews.blogspot.com</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"> .<br />
Also wanted to say that I had a problem with Nonovulin getting moldy after a
week when I mixed it with water, so I emailed the seller who recommended that
it not be mixed with water - I began using a pill crusher and mixing the
particles in with the wet food, just crushing enough each week for that
week's dose.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I saw a note about that somewhere,
so I am using a pill cutter and crushing to mix with wet food. Just got the
Nonovulin yesterday; administered the first dose in last night's feeding. The
instructions from the seller advise administering three times a week, but
I've read elsewhere once a week?<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post358" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#358</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 27, 2014</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Trish wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"><quoted text><br />
I saw a note about that somewhere, so I am using a pill cutter and crushing
to mix with wet food. Just got the Nonovulin yesterday; administered the
first dose in last night's feeding. The instructions from the seller advise
administering three times a week, but I've read elsewhere once a week?<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I'd definitely use Fairchild's
dosing chart, which only recommends twice weekly feedings for very large
groups of cats. I've tried without success to copy and paste the chart here
but if you go to </span><a href="http://floridacatnews.blogspot.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">floridacatnews.blogspot.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> , I've got a post titled "Nonovulin dosing
chart with MG column added" which will give you MG dosing per COLONY.
The original chart just had ML dosing since they use liquid Megace - I added
the MG dosing conversion..<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">24-ABZ<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">Rotherham, UK<o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post359" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#359</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Aug 22, 2014</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi,<br />
Thank goodness for a sensible advocate of cat contraception!!!!<br />
Just one thing....as my vet and other's in the area will not prescribe or say
'there's no such thing'.... as one with a Sphynx queen whom I hope will have
a litter or three one day but at 8 mths has had 3 consequetive, upsetting
seasons in two mths, do you have cause to think the contraception may not be
advisable for such a specialised pedigree??<br />
Helen xx<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">brenda<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/city/johnstown-pa"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Johnstown, PA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post360" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#360</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Sep 11, 2014</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Hi my name is brenda , I live in
johnstown pa n looking for HElP, to spay n neturd cats<br />
i have contacted so many people but noone is responding back to me there are
baby kittens and cats that need homes n i wanted to buy the birth control for
cats but no vet here will sell me the producd i wnt to stop the cats from
have kittens they are in jeberly of beinr killed or hurt.<br />
please any help will be apprisheated.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">momiecat<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post362" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#362</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 11, 2015</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">leslie leavitt wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">I have used
FeralStat on a feral colony for about 2 and a half years. Have not had one
kitten born in that time. The cats appear to be healthy. I will continue to
use it despite negative comments. The life of a feral is hard at best. They
are already subject to all kinds of illnesses and diseases and while the
thought of adding to their troubles with FeralStat is not my intention I will
continue to use it. Preventing feral kittens from being born is my goal at
this time. I have tried many times to trap these cats but they are very trap
wary.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Leslie, my feral cat colony
currently has about 7-8 cats. Is there any way you can write out some simple
instructions on how to mid the capsules with the distilled water and then use
a syringe to distribute the liquid dosage? It is hard for me to understand
unless there are numbered step-by-step instructions. Thank you.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">kymberleigh007<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/city/monrovia-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Monrovia, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post363" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#363</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 3, 2015</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I can't read the story b/c I don't
have an invitation from the blogger to read it....according to Google
Blogger!! Soooo frustrating how everything is tied to Google & Facebook
these days!! I just want information and not EVERYONE in my life to know what
Im doing/reading/etc. Grrrr!!!! I have a colony of 93 and I TNR religiously.
I have a ton of people asking for help and I just found out about feralstat
and now I can't even read about it!! Frustrated doesn't even cover it.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Christy<o:p></o:p></span></b></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post364" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#364</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 3, 2015</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">kymberleigh007 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">I can't read the
story b/c I don't have an invitation from the blogger to read it....according
to Google Blogger!! Soooo frustrating how everything is tied to Google &
Facebook these days!! I just want information and not EVERYONE in my life to
know what Im doing/reading/etc. Grrrr!!!! I have a colony of 93 and I TNR
religiously. I have a ton of people asking for help and I just found out
about feralstat and now I can't even read about it!! Frustrated doesn't even
cover it.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">kymberleigh007,<br />
I just tried to re-read the story. I was able to read it a month or two ago,
but I just got the same thing as you.(Need an invitation)<br />
It's my understanding they aren't making Feralstat at this time. However,
there are alternatives to it.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">catcandoo<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post367" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#367</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Apr 30, 2015</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">New delivery method for feratstat.
One girl can only feed dry food. She grinds the tablets of a fine powder and
dusts the dry food. Not a litter in 3 seasons.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">MnGrrl<o:p></o:p></span></b></div>
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<a href="file:///C:/forum/city/canby-mn"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Canby, MN</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="file:///C:/forum/med/TO5BM504OU9T4PASQ/post368" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#368</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Thursday May 28</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Have been using Nonovulin for 6
months now. What would have been 15 litters is now 5, and only because 3
queens will only eat dry food, 1 got pregnant before I started and 1 came as
a stray. Have tried to tell my vet and local rescues about it, but get
brushed off as essentially a kook. Disheartening, so please keep the info out
there.<br />
<br />
It does work, and at these low doses--I use 2 pills per 20 cats once a
week--I have had no side effects. I simply crush the pills in a morter and
pestle, and mix with a can of really tasty wet cat food. I try to give about
a half a teaspoon to each cat, so they get only a tiny, tiny dose.<br />
<br />
One thing I have noticed and Nonovulin warns about is it WILL interrupt
lactation. If one becomes pregnant (the dry food only eaters), I do try to
pull the Nonovulin away at least 3 weeks prior to birth. The one queen that
was pregnant "before dosing began" had her litter just fine, but
she had no milk. I saved 2 of the kittens by bottlefeeding for a week. She
soon came into milk and all are fine.<br />
<br />
There must be an awful lot of politics around this issue. I had written off
any contraceptive after finding the old bad-news stuff out there. But then I
had a different vet working on a horse here one day, who said to "look
into it through Google." However, when I went to get a prescription
through said vet, it was like the line went dead. So thank heavens for
Ebay.<br />
<br />
For the first time ever, I finally have a real chance at getting a handle on
my cat population. I wish this would go mainstream. It would avoid many
needless deaths of cats.<o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="file:///C:/Users/Freeman/Pictures/My%20Pictures/Projects/Beatrice/FeralStat%20contraceptive_%20ACCD%20statement%20-%20Feral%20Cats%20in%20the%20News%20-%20Discussion%20on%20Topix%2017%20if%2017.html"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">an<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post332" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#332</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Oct 29, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Megestrol acetate is
available on E-bay WITHOUT a prescription. See my</span><a href="http://birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">birthcontrolforcats.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> website for information on this.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">JKPC<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cathedral-city-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Cathedral City, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post333" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#333</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Oct 29, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I have ordered the
cat birth control from International Drug </span><a href="http://mart.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Mart.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> as directed on the website at the bottom of this post. I
note that the website now informs that the drug is available on eBay. I
haven't received or tried yet, but I do know that I have found it impossible
to keep ahead of the kittens with TNR. I found it very encouraging when
researching the drug, that it is used in humans for various treatments.
I may have taken it when myself when I was being treated
for estrogen based breast cancer and I am a survivor for
12 years now. I am really not worried about all the doom and gloom side
effects hinted at by various internet sources. Not one source gives
specific information. Wish me and the cats good luck and I will return next
spring to let you all know how it goes!<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">JKPC<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cathedral-city-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Cathedral City, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post334" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#334</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Oct 29, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I forgot
the website link but note that Dean posted it a earlier:</span><a href="http://birthcontrolforcats.com/index.htm" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">http://birthcontrolforcats.com/index.htm</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/albuquerque"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Albuquerque, NM</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post335" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#335</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Oct 29, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Don't know if
everyone knows or even cares after this exceptional site, but FeralStat is
available again. You can get it from Westlab Pharmacy. Your vet has to call
in the prescription, then they get in touch with you.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dean<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/marshall-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Marshall, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post336" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#336</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 6, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I have the info on
my website </span><a href="http://birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">birthcontrolforcats.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> about WestLab selling their version of
Feralstat clone. They sell about 300 scoop jars but you must have a RX for
it.<br />
<br />
For those unable to convince a vet to RX you MA, your best option is the
Bulgarian MA on Ebay or offshore pharmacies---no prescription needed.<br />
<br />
See my website for latest info on anything about MA for feral cats. I have
bought MA from WestLab with a RX as well as purchased it without a RX from
Ebay and offshore pharmacies such as Int'l Drug Mart.<br />
<br />
My website is meant as an informative site only. I have received hate mail
for putting the site up, something I knew would happen, but I simply ignore
the trolls and idiots that do so.<br />
<br />
If you find the site informative and helpful, please make
a donation to your local animal shelter or rescue group. I do NOT
accept or want donations--the site is strictly a labor of love for me.<br />
<br />
I hope the site has helped some of you out. I'll keep you posted as time
permits. Please keep me posted of your experiences with MA.<br />
<br />
Dean Jones<br />
</span><a href="http://www.birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">www.birthcontrolforcats.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/catcandoo" title="See catcandoo's profile"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;">catcandoo</span></b></a><b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Oct 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post337" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#337</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 6, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I have several
feeders now using this hormone. One group with about 125-150 cats among them
have not had a single litter of kittens this year. Other feeders that I can
keep track of that have maybe 100-125 total have reported 1 litter. Just read
the posts here and get the info to be successful. It is a life saver. 5574<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dean<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/marshall-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Marshall, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post338" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#338</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 6, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks for the
update catcandoo. That's good news to know.<br />
<br />
Just curious if they are using the same dosages as outlined here & on my
website? Also, are they using RX MA such as Westlab's or are they mixing with
water as outlined here and on website?<br />
<br />
Dean Jones<br />
</span><a href="http://www.birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">www.birthcontrolforcats.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">brenda<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post339" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#339</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 27, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">hi my name is brenda
and i live in johnstown pa.<br />
where i live there are a lot of stray cats and having kittens, my slef and a
few other people i know take care of cats and kittens .iwas catching some of
them and having them fixed and shots, and finding homes but not every one is
interested in giving cts and kittens homes. so what i would like very much is
to find out how to order this contraceptive. that would be most helpful to me
and many others here in johnstown pa.my email address is </span><a href="http://brendai542yahoo.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">brendai542yahoo.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><br />
any one with any helpfull infromation please contact me.I HAVE HAD A PERSON
ALREADY SHOT AND KILL 2 CATS WITH BOW AND ARROWS 1 WAS A MOTHER CAT W 3
UNBORN KITTENS WHICH DIED INSIDE HER DUE TO HER WOUNDS, AND SHE DIED 2 DAYS
LATER.I DID HAVE HIM CHARGED WITH CURELTY BUT HE DID"T GET BUT A FINE
AND PAY ME BACK FOR THE VET BILL FOR WE NEED TO ALSO GET TOUGHER CURLTY LAWS.
THANK YOU ALL<br />
<br />
THANK YOU ALL AND HAVE A SAFE AND HAPPY NEW YEAR.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/sandia-park-nm"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Sandia Park, NM</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post340" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#340</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 28, 2013</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dean: Thanks so much
for your labor of love. Without you a lot of us would be stuck, not knowing
what to do. Good karma to you You've earned it. Glad you are ignoring the
hate mail. Some people just don't have enough to do.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post341" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#341</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jan 15, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I've ordered and
received Nonovulin from the Bulgarian seller on EBay. As soon as I've used up
the last of my Feralstat I'll be giving it to three newcomers to my condo
complex (cats that is !). Thank you Dean for that source.<br />
<br />
I'm finding researching the pharmacy that makes Nonovulin difficult, but did
find that they do business with the FDA.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">JKPC<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/cathedral-city-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Cathedral City, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post342" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#342</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jan 17, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I want to mention
that if you are going to use this birth control on feral cats, you must be
able to make sure that you can give the proper dose to each cat once a week.
You must be able to manage that the cats do not jump from bowl to bowl which
is not easy with just one person or with feral cats. I now realize why this
form of BC has not been embraced by mainstream. I simply does not work for
most people who are doing their best to manage feral colonies. I'm back to
TNR on a regular basis and pray I can get most of them before the spring
kitten season.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">catcandoo<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post343" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#343</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jan 17, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">JKPC--Everyone one I
know who is using this BC (a total of roughly 300 cats) are thrilled with it.
Litters reduced to zero or one in the colonies. A local vet who is a big
supporter said that the health & death risks to the feral/stray cats of
bearing litter after litter, of the risk of pregnancy & delivery, of fighting
(10% problem pregnancies/delivery in tames), of having to stretch food
as the colony grows, is far worse than the administration of Feralstat. Keep
in mind you don't know how many cats you are feeding since very skittish ones
stay out of sight until you are gone. There are also areas where you can
never trap, but can feed. Imagine the lives of these cats without BC. We have
all prayed that we could beat the breeding drive and the illusive little
moms, and we were driven to use Feralstat for the sake of the cats.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dean<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post344" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#344</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jan 20, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">JKPC--you are wrong
in stating "I (sic) simply does not work for most people who are doing
their best to manage feral colonies."<br />
MA does indeed work for me (no new births) and for hundreds of
other feral cat colony caretakers from all over the world. I wish you could
see the many emails I get on my website from happy and satisfied users of MA
that MA has allowed them the chance to get control of their growing colonies
until proper TNR could be implemented.<br />
Keep in mind that MA is NOT an alternative to proper spay/neuter and TNR. One
should never stop TNR on a colony just because MA is working to keep the
population of the colony under control.<br />
Uncontrolled oral contraceptives & vaccines for various species have been
in use by game and wildlife officials for years in the wild in uncontrolled
environments with excellent results. In such instances, just like MA for us,
there is no way that game officials can control who "who gets what"
in a dose of oral contraceptives dropped from an airplane in the wild to
control certain species.<br />
The use of MA in a feral cat colony along with TNR is MUCH MUCH better than
NOT using it. Keep in mind that we are using very low dosages as well...much
less than dosages administered in all published studies done on the side
effects of MA.<br />
I still stand behind my conclusion that the reason MA has not been endorsed
by the "mainstream" is because of greed and money. There is no
money in MA for "Big Pharma" and others who wish to line their
pockets with mega-buck$ from contraceptives for dogs and cats.<br />
I will bet dollars to donuts that if the "mainstream" does come out
with an alternative to MA that (1) it will be expensive & under patent
for years & controlled by a major pharmaceutical company (2) it will have
to be administered in a vet office by a vet or medical personnel (thus
leaving us feral colony caretakers "in the cold again").<br />
I now am aware that there are efforts to try to bring to market (once again)
a dog food laced with oral contraceptives. However, we are YEARS & YEARS
away from seeing this in the USA and it will be administered first in other
countries. </span><a href="http://600milliondogs.org/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">http://600milliondogs.org/</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><br />
This effort was tried back in the 70's & 80's by The Carnation Company
but it was squelched. I go into detail about "why" it was shelved
on my</span><a href="http://birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">birthcontrolforcats.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> site.<br />
The bottom line is MA does indeed work in low dosages...it is inexpensive
(sometimes less than .11 cents per pill) and is now easily obtainable without
a RX thanks to all the hard work and investigative efforts put forth by the
dozens of people on this thread.<br />
I hope all of you that are using MA in controlled low dosages continue to do
so. MA has prevented millions of unwanted kittens in the past few years
alone...it does work.<br />
Dean<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dean<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post345" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#345</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jan 20, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">In re-reading my
previous post, some may get the wrong idea by my statement that MA "is
now easily obtainable without a RX thanks to all the hard work and
investigative efforts put forth by the dozens of people on this thread."<br />
<br />
MA is still available only by RX in the USA. However, it can easily be
obtained from Ebay or off-shore online pharmaceutical companies.<br />
<br />
And again, for those that email me, I do NOT sell or distribute MA. All of
the questions you have concerning how to obtain MA without a RX are answered
by going back and reading a few previous posts in this now 4 yr old thread,
or you can visit my </span><a href="http://birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">birthcontrolforcats.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> website.<br />
<br />
Dean<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">catcandoo<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post346" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#346</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jan 29, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">DEAN, sorry I missed
your question earlier about dosing in post #338. No, we don't use the dosing
in your website. There were already 2 dosing protocols being used in the area
and those are what are being used. Another girl powders it and sprinkles on
kibble because that's the only way she can do it. Works great for her.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">catcandoo<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post347" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#347</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jan 29, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">BARBARA, I tried to
email you at the addy in your post #308 to get your word doc that gives a
digest of dosing schedules found in the forum, but it came back
undeliverable. Would still like to have it.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dean<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post348" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#348</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Mar 13, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I thought this
thread had vanished and was deleted by Topix as Topix moved their forums
around a few weeks ago...glad we still have it going here as I just happened
to "re-discover" it by using Google.<br />
<br />
With spring approaching, I'm curious to hear from colony caretakers out there
if they have any new litters or signs of pregnancy after using MA.<br />
<br />
I have changed the links to this thread on my website so if former readers of
this thread are lost, they can easily find it by going to my site.<br />
<br />
I will soon update my site for you to download a translated French document
of a French study done on the minimal side effects of MA. Barbara and I
worked hard on the translating the French document to English and we now have
a translated PDF document for those of you that may wish to show your vet to
help squelch the misconceptions and myths of adverse side effects of MA.<br />
<br />
Dean<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">catcandoo<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post349" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#349</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Mar 13, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Dean, thanks. All
the studies that help us will help kitties. So far, the people in my network
are thrilled to use MA. In the whole 300 or so cats, only 2 litters have been
reported. Could be the mom was dumped recently, or just didn't get enough MA.
The feeders said the 2 moms were not familiar to them, but that can happen
with shy kitties anyway.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p16"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">cathy<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/santa-cruz-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Santa Cruz, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post351" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#351</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Mar 24, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I just got mine on
eBay...Thank God.....My best friend is overwhelmed by cats,we can't
catch...Silly how easy it is.....How wonderful that we have such a place to
go for help....We and our cat friends are soooooo thankful to you:-) :-) :-)
:-) :-)<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Stacie C<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/stockton-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Stockton, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post352" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#352</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Jun 15, 2014</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Time is all I need! MA
on its way! Thanks stumbled upon</span><a href="http://birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">birthcontrolforcats.com</span></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> Great information. I live in Stockton
Ca. talked with a few other caretakers from northern California area .not one
had heard about MA. WOW .<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post307" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#307</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 14, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">JKPC, I and others here are
currently working on a website that will thoroughly explain the
uses of megestrol acetate in very small doses to prevent estrus in feral
cat colonies.<br />
<br />
Barbara here on this thread has also put together a very nice concise and
abridged/condensed version of the main topics/guidelines of this entire
thread, which now has been ongoing for about 2 years.<br />
<br />
Barbara also did a nice research paper on her own compiling cases
of side effects of using MA in cats for estrus prevention.<br />
<br />
As for side effects, as we all know here that
have stuck diligently with this thread, the conclusion of side
effects of MA is practically ZERO side effects if used in
proper/low doses as we have all discussed here.<br />
<br />
JKPC, until the website is up and running, which may be after Christmas, I
suggest that you go back and read this thread in its entirety, paying extra
attention to the last 200 or so posts...all the information you need for a
presentation to others is here in this thread...it is just "spread
out" a bit & will require some reading on your part.<br />
<br />
Until the website gets up and live, take some time and peruse this
thread...many, many people here have put a LOT of valuable time and effort
into this for all others to learn from.<br />
<br />
The entire purpose of the upcoming website will strictly be to educate rescue
groups, veterinarians, feral cat owners, etc. that MA can be used until we
can get ahead on TNR. Just keep in mind that MA is NOT a substitute for
spay-neuter but is meant to complement it until proper TNR can be performed
on a colony.<br />
<br />
And while I'm on the subject of the future website, I have seen preliminary
main pages of it in design form...in keeping with the Christmas tradition, I
have to say that the first page looks really cool and appropriate...<br />
<br />
Spoiler hint:<br />
<br />
Webpage starts out with "Yes, Virginia, there REALLY is affordable birth
for feral cats!..." (With apologies to Ms. Virginia O'Hanlon, the little
girl that originally wrote the famous letter to the newspaper in 1897 asking
if there was a Santa Claus and apologies also to Francis Pharcellus Church the
editor who was given the task to reply to the little girl's question with his
now famous editorial..)<br />
<br />
It will be great and informative website for all to see and help prevent the
births of millions of unwanted litters.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post308" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#308</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Dec 14, 2012</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">JKPC- I've put together a summary
of my experience with Feralstat/MA along with the studies I found related to
MA on my website </span><a href="http://www.floridacatnews.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">www.floridacatnews.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> .<br />
<br />
If you want to email me, I can send you the Word document where I copied most
of the postings about dosing from this discussion. My email address
istnrmakessense@grmail.com<br />
<br />
I think one of the best contacts to share is Dr. Jennifer Fry at Fairchild
Foundation in Berks County Pa. Her email address
isfairchildfoundation@gmail.com and their site address is </span><a href="http://fairchildcat.org/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">fairchildcat.org</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> .
She has used MA for over 10 years.<br />
<br />
Barbara<br />
<br />
<!--[if !supportLineBreakNewLine]--><br />
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">JKPC wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Thanks for your responses to my inquiry!<br />
I have a the head of feral rescue group (affiliated with a local shelter
which the group influenced to become a no-kill) coming tomorrow to do a mass
trapping for TNR.<br />
I met with her today when she delivered a new large group trap & asked
why they weren't using "the pill for cats". She was unaware of
MA/Feralstat and asked why it wasn't mainstream. I said I imagined it had to
do with FDA. She also expressed concerns about side affects. I said if we
woman can use a pill why can't cats? How bad would it be for a male to get a
low dose?(We LOL about that & agreed the world might be a more peaceful
place - no offense to you guys intended, really).<br />
After cries for help to many rescue groups over several years, I was directed
to thislocal group as they are affiliated in their TNR program with Best
Friends in Kanab, UT. Being new to this thread, there is lots
of reading to get to the important facts.<br />
Would one of you who has participated in this thread over the years please
post the important facts in summary form so I can print and give to
this woman? She is a successful, high profile business woman here
in SoCA & is committed to improving the quality of life for "community"/feral
cats and she has contacts with Best Friends. She possibly could be a
tremendous help to the kitty birth control movement.<br />
THANK YOU!<o:p></o:p></span></i></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post310" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#310</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 1, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">For everyone that has followed
this thread for almost two years, we now have a website up that
thoroughly explains mixing, dosing, etc. of megestrol acetate. It is
basically a condensed version of this 2 year old discussion thread, all in
one easy-to-read website.<br />
<br />
The website is:<br />
<br />
</span><a href="http://www.birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.birthcontrolforcats.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
A thank you to my friend Dean for designing the site. A big thank you to all
of you that have followed and contributed to this discussion over the years.<br />
<br />
A website was long overdue for feral caretakers concerning birth
control.<br />
<br />
What a nice way to start out 2013. I hate to see this Topix thread come to an
end--maybe it will still receive posts from time to time.<br />
<br />
To all my friends here, Happy New Year...it's time to move on.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ellen<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/hicksville-ny"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Hicksville, NY</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post312" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#312</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 2, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">kcook924 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Did the FeralStat
work? I am faced with the same problem as many out there are.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Yes, FeralStat worked for me and
other caretakers in my area. The cats have since been neutered and had no
issues because of the FeralStat they were given for 9 months prior to their
TNR. In fact, they looked great. I now have 5Colonies with new cats
showing up all the time. I'm extremely upset that FeralStat was taken off the
market. There's no way to TNR all these cats, some of whom won't go near
traps of any kind. If anyone knows where I can purchase FeralStat, please let
me know. Of course, I intend to have as many cats as possible neutered, but
in the meantime, FeralStat is the only other option I have. Thank you. Ellen.
4loveofcats@optimum.net<o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/member/profile/jkpc" title="See JKPC's profile"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.5pt;">JKPC</span></b></a><b><span style="font-family: "times new roman" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Dec 12<o:p></o:p></span></div>
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<i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;">SoCAL<o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post313" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#313</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 2, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thank you James! Thank you
Barbara! A BIG thanks from me personally and all the community cats that I
feed, love and do my best to care for. Over the last month I have been able
to TNR five cats but currently I don't think my efforts will stay head of the
birth curve. I am so grateful for all the information shared on FeralStat!!
Happy New Year Lucky #13 starting off with your new web site!!<br />
Janis<br />
Palm Desert, CA<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">BusyBee<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/winder-ga"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Winder, GA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post314" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#314</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 2, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Ellen wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"><quoted text><br />
Yes, FeralStat worked for me and other caretakers in my area. The cats have
since been neutered and had no issues because of the FeralStat they were
given for 9 months prior to their TNR. In fact, they looked great. I now have
5 Colonies with new cats showing up all the time. I'm extremely
upset that FeralStat was taken off the market. There's no way to TNR all
these cats, some of whom won't go near traps of any kind. If anyone knows
where I can purchase FeralStat, please let me know. Of course, I intend to
have as many cats as possible neutered, but in the meantime, FeralStat is the
only other option I have. Thank you. Ellen. 4loveofcats@optimum.net<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ellen, I sent you an email.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post315" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#315</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 2, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thank you for the compliment
Janis. All thanks go to my friend Dean for doing the site by condensing all
the info into detailed, but easy to follow guidelines for all to read and
follow.<br />
<br />
Also, there has been some question about the "Pet Vet Tips" page
having a login box asking for a username. Dean tells me that is just
experimental page for now & no information is actually on that site, he
just plans to put up future tips for money saving on vet bills and he was
just experimenting with a lockedlogin page. I think he likes to play with
source code.:)<br />
<br />
Also, I answered your guestbook post about a Facebook link on the guestbook
itself. As I said, I'm ignorant on Facebook. I've never used it. Any help you
can give me on getting a Facebook link setup is appreciated.<br />
<br />
I'm glad to see this thread is still active.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post316" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#316</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jan 2, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Ellen, I know BusyBee sent you an
email. Thank you BusyBee. I also sent you one too Ellen.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Laurie<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/bakersfield-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Bakersfield, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post319" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#319</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 20, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">janeyjan wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"><quoted text><br />
Hi Mommameow,<br />
If you would contact the CatsafratRX online, and ask for a supply of ovaban,
they would be able to help you..or..<br />
If you would email me, perhaps I could offer my help,<br />
My heart goes out to you, as I know how frustrating unwanted kittens can be.
Janey<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Janey,<br />
We had a feral cat colony here two years ago and had been using Feralstat.
The colony dwindled from 35 cats down to three! When we called Dr, John to
get more, we were informed that he had passed away and that Feralstat was
wrapped up in probate. We are now contending with two pregnant females and
the beginning of something that we thought we had well under control. We are
in dire need of a solution as we now have a neighbor who is trapping and
turning these cats into a shelter. We need help! I'd appreciate any
information that you can offer.<br />
Laurie<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/dallas"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post320" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#320</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 20, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Laurie,<br />
Call CatsafratRX and talk to them... Very very helpful people with a heart
for what we do! Google the name and get their contact info - one of the best
phone calls I have ever made!<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Laurie<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/bakersfield-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Bakersfield, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post321" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#321</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 20, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Mommameow wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Laurie,<br />
Call CatsafratRX and talk to them... Very very helpful people with a heart
for what we do! Google the name and get their contact info - one of the best
phone calls I have ever made!<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Thank you so much!!!! It's nice to
know we aren't alone in all of this. I appreciate the help :-)<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">francie5<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/brooklyn-ny"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Brooklyn, NY</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post322" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#322</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 26, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">i just ordered today from
CatsafratRX!!! i have to try it .... my last colony cost me over $600 to
finally fix it....and of course, we have new cats all the time. i am willing
to take a chance with any health concerns because i simply cannot afford to
maintain these colonies forever. i dont want them to outlive me!!!!! this is
a wonderful site.....nice to know i am not the only one out there helping
these ferals.....i love reading the letters.<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Laurie<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/bakersfield-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Bakersfield, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post323" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#323</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 26, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Francie..I just ordered my batch
today as well. It's time to get a handle on this colony before we too, get
overwhelmed again. We used Feralstat for years with much success and it's
GREAT to know that we can get some kind of control over this! Thank you soooo
much CatsafratRX!!!!<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/albuquerque"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Albuquerque, NM</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post324" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#324</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Feb 26, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">francie5 wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">i just ordered today
from CatsafratRX!!! i have to try it .... my last colony cost me over $600 to
finally fix it....and of course, we have new cats all the time. i am willing
to take a chance with any health concerns because i simply cannot afford to
maintain these colonies forever. i dont want them to outlive me!!!!! this is
a wonderful site.....nice to know i am not the only one out there helping
these ferals.....i love reading the letters.<o:p></o:p></span></i></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Is this stuff a prescription item
or what. I notice that their site says that all prescription items they will
call your vet.<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "times new roman" , "serif"; font-size: 7.5pt;">Since: Oct 12<o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post325" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#325</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 3, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Where on </span><a href="http://fairchildcat.org/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">fairchildcat.org</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> can
I find Dr. Fry's information on using MA? I can't find it but do want to read
it. Thanks.<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Barbara in Orlando wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">JKPC- I've put together a summary of my experience with
Feralstat/MA along with the studies I found related to MA on my website </span></i><a href="http://www.floridacatnews.com/" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">www.floridacatnews.com</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"> .<br />
If you want to email me, I can send you the Word document where I copied most
of the postings about dosing from this discussion. My email address is
tnrmakessense@grmail.com<br />
I think one of the best contacts to share is Dr. Jennifer Fry at Fairchild
Foundation in Berks County Pa. Her email address is
fairchildfoundation@gmail.com and their site address is </span></i><a href="http://fairchildcat.org/" target="_blank"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">fairchildcat.org</span></i></a><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;"> . She has used MA for over 10 years.<br />
Barbara<br />
<quoted text><o:p></o:p></span></i></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post326" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#326</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Mar 6, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Catcondo, you can read Fairchild
Cat's info on use of MA here:<br />
<br />
</span><a href="http://www.fairchildcat.org/rich_text_1.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.fairchildcat.org/rich_text_1.html</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
<br />
Scroll down to bottom of page.<br />
<br />
For those that seem to have problems finding MA/Feralstat, the website we set
up, </span><a href="http://birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">birthcontrolforcats.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> pretty much explains everything in a concise and
easy to understand manner. As for actually buying it here in USA, unless you
have a Dr. RX, you will have to resort to offshore pharmacies.<br />
<br />
However, many here have had success with CatsafratRX. Read back over the
thread here for all the info on CatsfratRx...the info is here on this thread,
just read back over old posts.<br />
<br />
The </span><a href="http://birthcontrolforcats.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">birthcontrolforcats.com</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"> site will soon be updated as Dean did successfully
purchase and receive Megace tablets in 40 mg form from an offshore pharmacy
without an RX--check the site soon for updates for those of you having
trouble obtaining MA tablets.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">RaeN<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/bath-ny"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Bath, NY</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post327" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#327</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 26, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I want to thank everyone here from
the bottom of my heart for giving me hope to dry the tears I've been shedding
so many of lately. I used to have five indoor cats.... all spayed/neutered.
At some point a few years ago strays started to show up... a couple here and
there and every so often I'd see a new face creeping up out of the woods and
then the kittens started showing up. Well, I know I don't have to repeat the
story to those of you who know it so well. I've trapped and spayed a female
here and there as I can afford to but the situation is so out of control that
I spend nights crying, frightened of where it's all headed. The vet here
offers a feral discount at over $100 a cat. That just doesn't work out very
well for a couple old folks with a part time and SSD income, but we do try.
I'm feeding a colony of 30 or so, it's hard to keep count for sure since most
are tabby or all black. I have no idea where or how I'm going to find this
medicine but you've given me a place to start and *HOPE*... Bless you...<o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">Mommameow<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/dallas"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Dallas, TX</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post329" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#329</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jun 26, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.catsafratsrx.com/" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 10.0pt;">http://www.catsafratsrx.com/</span></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><br />
Call these great people and start your search there ....<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">RaeN wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "times new roman" , "serif"; font-size: 8.5pt;">I want to thank everyone here from the bottom of my heart for
giving me hope to dry the tears I've been shedding so many of lately. I used
to have five indoor cats.... all spayed/neutered. At some point a few years
ago strays started to show up... a couple here and there and every so often
I'd see a new face creeping up out of the woods and then the kittens started
showing up. Well, I know I don't have to repeat the story to those of you who
know it so well. I've trapped and spayed a female here and there as I can
afford to but the situation is so out of control that I spend nights crying,
frightened of where it's all headed. The vet here offers a feral discount at
over $100 a cat. That just doesn't work out very well for a couple old folks
with a part time and SSD income, but we do try. I'm feeding a colony of 30 or
so, it's hard to keep count for sure since most are tabby or all black. I
have no idea where or how I'm going to find this medicine but you've given me
a place to start and *HOPE*... Bless you...<o:p></o:p></span></i></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">NrmNp<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/city/tempe-az"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Tempe, AZ</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post330" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#330</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 6, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">There is a woman who does not live
in our neighborhood who is putting dowm about 5 pounds of cheap cat food in
our alley between 1 and 2 am every morning. The police say someone has to
call it in and they need to catch her in the act before they can write her a
ticket for littering. We're overwhelmed with cats. It's over $90 to turn them
and a smaller 'donation' fo TNR if you trap yourself. I'm tired of seeing
starving and dead kittens my backyard. Very sad situation. I hope I can get
something done with this megastrol acetate.<o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">leslie leavitt<o:p></o:p></span></b></div>
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<a href="http://c2.rfihub.net/forum/albuquerque"><i><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Albuquerque, NM</span></i></a><i><span style="font-family: "times new roman" , "serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/post331" title="Post Permalink"><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">#331</span></a><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 9.0pt;">Jul 6, 2013</span><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;">I don't know if everyone knows
this or not but you can get Feralstat from Westlabs, the original pharmacy.
You need a vet prescription or your vet can call in an order, then you call
them.<o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Reply with quote"><b><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://c2.rfihub.net/static/js/personalize/templates/hotel/300/"><b><span style="color: #898989; font-family: "times new roman" , "serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="font-family: "times new roman" , "serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #5b5b5b; font-family: "roboto" , "serif"; font-size: 16.5pt;">Tell
me when this thread is updated:<o:p></o:p></span></b></div>
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<span style="color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;"> </span><span style="color: #5b5b5b; font-family: "roboto" , "serif"; font-size: 10.5pt;">of 17</span><span style="color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;"><o:p></o:p></span></div>
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<span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"> </span><a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/p16"><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;">Next</span><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt; text-decoration: none;"> </span></a><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"> </span><a href="http://c2.rfihub.net/forum/med/TO5BM504OU9T4PASQ/p17"><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt;">Last</span><span style="background: #0060cd; color: #dedede; font-family: "roboto" , "serif"; font-size: 10.5pt; text-decoration: none;"> </span></a><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"><o:p></o:p></span></div>
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<span style="color: #5b5b5b; font-family: "roboto" , "serif"; font-size: 13.5pt;">Add your comments below<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/monroe-ga"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">GA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post287" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#287</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">I think the reason
that so much of this info we've all uncovered on feline contraception is so
sketchy and "hidden" is that the veterinary association does NOT
want feline/canine contraception. This is only my conclusion. I just think
there's too much money to be lost by vets if there was declining birth rates
in cats & dogs.<br />
As for feral colonies being "flea-free" after dosed with MA..the
more I think about it, colonies dosed with MA and being fed properly on a
regular basis does make a much healthier colony. With no females in estrus in
the colony, there is not as much fighting, competition, etc. Fleas are
attracted to cats/dogs in poor health. A healthy cat usually has less fleas
than an unhealthy one...just my thoughts.<br />
A friend of mine is considering setting up a website...a sort of
"what happened to Feralstat" or "An Alternative To
FeralStat"..just sort of a way to make this info more widely known for
feral caretakers...what do some of you think about this?<br />
James<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I think this is a
wonderful idea! Thanks James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post288" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#288</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">My friend is willing
to buy the domain name to disseminate the ifno we've all uncovered about
using MA in liquid suspension in place of actual<br />
<br />
The question I have, what do some of you think the domain name should be?<br />
<br />
I'm open for suggestions....give me your input. Guess we need it to be simple
& easy to remember and tell others about it without much chance for
spelling errors...<br />
<br />
Some ideas:<br />
whathappenedtoferalstat DOT com<br />
<br />
felinebirthcontrol DOT com<br />
<br />
birthcontrolforferals DOT com<br />
<br />
Any of you have other suggestions?<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Randall<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">San Cesareo, Italy<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post289" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#289</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Or:
feralcatbirthcontrol DOT com?<br />
<br />
Randall<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post290" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#290</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">How about
"NoMoreFeralKittens DOT com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post291" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#291</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James - if your target audience is people
outside of the TNR /rescue world, I wouldn't use "feral" in the
domain name since 90% of people either don't know the term or have a negative
association with it.<br />
<br />
FYI, after a post I read on another blog about the FDA being responsible for
Feralstat being off the market I searched the FDA website, both regular
and veterinary drugs and recalls,voluntary withdrawals, and safety alerts and
there was nothing at all for "Feralstat".<br />
<br />
I also read through the FDA guidelines for veterinarians as far as
prescribing human drugs to animals, and they're given pretty wide
latitude.<br />
<br />
As far as the trademark, John Caltabiano is listed as
"registrant" but I didn't check to see how the registrant passing
away affects the trademark status.<br />
<br />
My two cents - after advocating for humane treatment of feral cats here in
Florida for years and coming up against a few well connected cat haters whose
life goal seems to be keeping catch-and-kill the method of choice for
"controlling" feral cats through animal control, it doesn't
surprise me when anyone walks away from public endorsement of TNR/feral birth
control. These people are vicious and tireless.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post292" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#292</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barabara, you are
right about the majority of the public not knowing what the word
"feral" means.<br />
After I made my post above about the domain having the word
"feralstat" in theDOT com site, I began to wonder about myself
about trademark infringement...probably best the word "feralstat"
be left out of the domain name.<br />
<br />
I too have run up against the cat-haters and know exactly what you mean about
that.<br />
<br />
I myself too do not think that Feralstat was pulled because of FDA...if it
had been, there would be record of it on the web somewhere. The ones that
keep saying the FDA pulled Feralstat can't ever offer one shred of evidence
to support that. Even some veterinarians erroneously report this as well, a
perfect example was the post I posted here a few months ago about those vets
that are on the payroll at one of those askDOTcom websites where a person
asks a question and then pays the vet online when they answer it--lots &
lots of erroneous information being "sold" to customers by these
online vets when they ask about Feralstat. Not a single one of them ever
quote this Topix thread or offer alternatives to their customers when asking
about alternatives to Feralstat.<br />
<br />
I think if there was a simple website setup with a condensed
version of what we all have found out here on our own about a safe
alternative to Feralstat, more & more unwanted litters would be
prevented, plus the public and vets themselves would be more educated about
feline contraception.<br />
<br />
My friend has offered to set up a simple website for this purpose
and I will supply him with the condensed & correct methods/info of mixing
and dosing the MA, thus the public would not have to wade thru this now 2-yr
old Topix thread for info on Feralstat alternatives.<br />
<br />
Last weekend, I visited a large business and the employees there had
"adopted" a small colony of feral cats on the premises..all
employees feed them daily and they are trying their best to TNR the colony,
but they can't get ahead of the game. I told them about MA and this
thread...they are now in process of buying MA and mixing themselves until
they can TNR the whole colony. The employees had no idea a feline
contraceptive existed and neither did their vet (supposedly).<br />
<br />
Keep suggesting domain names folks....I'll keep you posted..<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post293" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#293</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I think the
site is a great idea. Anything that can be done should be done to spread
the word that we finally have an edible birth control for cats. Especially
since it looks as if this is going to have to be a grassroots movement since
the large groups can't/won't endorse it.<br />
<br />
If you need it, I copied all but the last couple posts from this thread that
discussed dosage and where to get MA in to a Word doc.<br />
<br />
As far as a name - what about catbirthcontrol dot com.<br />
<br />
Barbara<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post294" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#294</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">What about:<br />
<br />
BirthControlForCats DOT com ?<br />
<br />
Easy to remember and spell...<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
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style='width:15pt;height:15pt;visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file:///C:\Users\Freeman\AppData\Local\Temp\msohtmlclip1\01\clip_image001.gif"
o:title="blank"/>
</v:shape><![endif]--><!--[if !vml]--><img alt="http://static.topixcdn.com/pics/blank.gif" border="0" height="20" src="file:///C:/Users/Freeman/AppData/Local/Temp/msohtmlclip1/01/clip_image002.png" v:shapes="Picture_x0020_14" width="20" /><!--[endif]--></span><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">BusyBee<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/monroe-ga"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Monroe, GA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post295" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#295</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">What about:<br />
BirthControlForCats DOT com ?<br />
Easy to remember and spell...<br />
James<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I like your idea and
also "Barbara in Orlando" suggestion of CatBirthControl dot
com<br />
BirthControl4Cats dot com (yours in another way :)<br />
<br />
Did you get my email, James?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post296" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#296</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Busy Bee, I like
your suggestion as well. Yes, I did get your email...you should have received
a reply by now..if not, email me back & I will resend it.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post297" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#297</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando:
Another good suggestion you have there for a domain name...I may just see if
my friend will register two names and point the DNS settings to one
site, that way we can be covered with two easy to remember names...after a
few more suggestions for domain names, then maybe we can all decide and I'll
send the domain names to my friend and let him register itwith domain
services and then he can work on getting a web site up &
running.<br />
<br />
The MS Word document would be great to have with all the
dosages listed. I can PDF it with Acrobat Pro X and people
visiting the site would have access to a PDF as well
as MS Word documents.<br />
<br />
Last night while researching more on megestrol acetate for feline
contraception, I ran across some foreign websites that referred to a drug
known as "Megecat"...turns out this is a feline contraceptive prescribed
by vets in other countries such as Belgium, Switzerland, etc. I haven't
researched much more on the dosages, but it seems like it has been used for
some time in other countries. I wonder why so many vets here in USA are
unaware of MA in felines for contraception?? Hmm...just strengthens my
hypothesis that there is too much $$$ involved in feline contraception here
in the USA and the drug companies can't patent MA, thus we have to wait years
& years for ACCD and FDA and drug companies to bring AFFORDABLE
contraceptives for cats and dogs to market, if they ever do.<br />
<br />
Barbara, you hit the nail on the head when you said this is turning into a
grassroots effort. I'm glad we all stuck with this for the sake of the
kitties as well as the caretakers.<br />
<br />
I'm sure when the website goes up there will be all the naysayers and hate
mail coming in from all over...I'm sure it will be bombarded...I know that is
a "given"...I'm just surprised this thread itself has stayed so
"clean" and not hijacked by the naysayers.<br />
<br />
When I read your post Barbara, it reminded me of this quote: "Never
doubt that a small group of thoughtful, committed citizens can change the
world; indeed it's the only thing that ever has." -Margaret Mead<br />
<br />
I'll keep you all posted on progress of the website as other suggestions come
in.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post298" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#298</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Where can I get
megestrol acetate/feralstat or ovaban?<br />
Do I have to involve a vet?(Not likely here.)<br />
The neighborhood is being over run by ferals. It is not feasible or
affordable to trap & neuter all of the cats. Esp. with no help from
neighbors or rescue groups. THANKS for any information you can provide.<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Oct 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post299" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#299</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">You can google to
find megestrol acetate on non-prescription foreign sites. Any MA strength
will do. You would just have to break it down for the dosing protocol you
choose. I've seen 2 so far, but have not read the entire site right here. Because
only small amounts would be ordered, the product comes into the country
relatively smoothly. What we would use for cats is not enough to make customs
think we are setting up a resale operation.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post300" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#300</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James - I emailed
you the Word doc. with the MA dosage discussions from this forum - please let
me know if you don't get it. Sorry about the delay - for some reason I don't
get all notifications of new postings and just got one today.<br />
<br />
As far as Megecat, that's interesting and not surprising. When I was
searching PubMed for MA studies I noticed that vets outside the US often
offered the full text of their studies for free on-line where very few if any
studies from US vets were available in full. It's all very discouraging.<br />
<br />
Thanks for the inspirational quote.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post301" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#301</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I got it Barbara...I
have replied via email to you.<br />
Thank you so much!<br />
<br />
Website will be up soon--may just be after Christmas though.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Debbie<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post302" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#302</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">So where can this
product be purchased. I have several kittens this year. More than last year.
ANd I would love to help keep this from happening. Too many cats that aren't
wanted.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Debbie in Texas<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post303" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#303</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I would love to find
this product or anything like it. Any help anyone can give would be greatly
appreciated.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post304" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#304</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Did you read posting
# 260 ? Excellent info. about approaching a vet about prescribing MA. My
first request was a "no" (and he charged me for the visit) but that
was a learning experience and I'll keep trying.<br />
<br />
#269 and #299 mention ordering from foreign sources.<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">JKPC wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Where can I get megestrol acetate/feralstat or ovaban?<br />
Do I have to involve a vet?(Not likely here.)<br />
The neighborhood is being over run by ferals. It is not feasible or
affordable to trap & neuter all of the cats. Esp. with no help from
neighbors or rescue groups. THANKS for any information you can provide.<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">steveh<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/hudson-ma"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Hudson, MA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post305" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#305</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara, Did the
money grubbing bastard even give you a reason why. You should have told him
to put his/her bill "where the sun don't shine"!!!! Please post his
name & address - I'll be glad to contact him & it won't be to wish
him/her a Merry Christmas. Good luck in finding a vet willing to write you a
perscription - they're out there so don't give up. Steve<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/jkpc" title="See JKPC's profile"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;">JKPC</span></b></a><b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Dec 12<o:p></o:p></span></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">SoCAL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post306" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#306</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks for your
responses to my inquiry!<br />
I have a the head of feral rescue group (affiliated with a local shelter
which the group influenced to become a no-kill) coming tomorrow to do a mass
trapping for TNR.<br />
I met with her today when she delivered a new large group trap & asked
why they weren't using "the pill for cats". She was unaware of
MA/Feralstat and asked why it wasn't mainstream. I said I imagined it had to
do with FDA. She also expressed concerns about side affects. I said if we
woman can use a pill why can't cats? How bad would it be for a male to get a
low dose?(We LOL about that & agreed the world might be a more peaceful
place - no offense to you guys intended, really).<br />
After cries for help to many rescue groups over several years, I was directed
to this local group as they are affiliated in their TNR program with Best
Friends in Kanab, UT. Being new to this thread, there is lots of reading to
get to the important facts.<br />
Would one of you who has participated in this thread over the years please
post the important facts in summary form so I can print and give to this
woman? She is a successful, high profile business woman here in SoCA & is
committed to improving the quality of life for "community"/feral
cats and she has contacts with Best Friends. She possibly could be a
tremendous help to the kitty birth control movement.<br />
THANK YOU!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/monroe-ga"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">GA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post287" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#287</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">I think the reason
that so much of this info we've all uncovered on feline contraception is so
sketchy and "hidden" is that the veterinary association does NOT
want feline/canine contraception. This is only my conclusion. I just think there's
too much money to be lost by vets if there was declining birth rates in cats
& dogs.<br />
As for feral colonies being "flea-free" after dosed with MA..the
more I think about it, colonies dosed with MA and being fed properly on a
regular basis does make a much healthier colony. With no females in estrus in
the colony, there is not as much fighting, competition, etc. Fleas are
attracted to cats/dogs in poor health. A healthy cat usually has less fleas
than an unhealthy one...just my thoughts.<br />
A friend of mine is considering setting up a website...a sort of
"what happened to Feralstat" or "An Alternative To
FeralStat"..just sort of a way to make this info more widely known for
feral caretakers...what do some of you think about this?<br />
James<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I think this is a wonderful
idea! Thanks James<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post288" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#288</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">My friend is willing
to buy the domain name to disseminate the ifno we've all uncovered about
using MA in liquid suspension in place of actual<br />
<br />
The question I have, what do some of you think the domain name should be?<br />
<br />
I'm open for suggestions....give me your input. Guess we need it to be simple
& easy to remember and tell others about it without much chance for
spelling errors...<br />
<br />
Some ideas:<br />
whathappenedtoferalstat DOT com<br />
<br />
felinebirthcontrol DOT com<br />
<br />
birthcontrolforferals DOT com<br />
<br />
Any of you have other suggestions?<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Randall<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">San Cesareo, Italy<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post289" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#289</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Or:
feralcatbirthcontrol DOT com?<br />
<br />
Randall<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Annie<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/naperville-il"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Naperville, IL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post290" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#290</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 27, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">How about "NoMoreFeralKittens DOT
com<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post291" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#291</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James - if your target audience is people
outside of the TNR /rescue world, I wouldn't use "feral" in the
domain name since 90% of people either don't know the term or have a negative
association with it.<br />
<br />
FYI, after a post I read on another blog about the FDA being responsible for
Feralstat being off the market I searched the FDA website, both regular
and veterinary drugs and recalls,voluntary withdrawals, and safety alerts and
there was nothing at all for "Feralstat".<br />
<br />
I also read through the FDA guidelines for veterinarians as far as
prescribing human drugs to animals, and they're given pretty wide
latitude.<br />
<br />
As far as the trademark, John Caltabiano is listed as
"registrant" but I didn't check to see how the registrant passing
away affects the trademark status.<br />
<br />
My two cents - after advocating for humane treatment of feral cats here in
Florida for years and coming up against a few well connected cat haters whose
life goal seems to be keeping catch-and-kill the method of choice for
"controlling" feral cats through animal control, it doesn't
surprise me when anyone walks away from public endorsement of TNR/feral birth
control. These people are vicious and tireless.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post292" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#292</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barabara, you are
right about the majority of the public not knowing what the word
"feral" means.<br />
After I made my post above about the domain having the word
"feralstat" in theDOT com site, I began to wonder about myself
about trademark infringement...probably best the word "feralstat"
be left out of the domain name.<br />
<br />
I too have run up against the cat-haters and know exactly what you mean about
that.<br />
<br />
I myself too do not think that Feralstat was pulled because of FDA...if it
had been, there would be record of it on the web somewhere. The ones that
keep saying the FDA pulled Feralstat can't ever offer one shred of evidence
to support that. Even some veterinarians erroneously report this as well, a
perfect example was the post I posted here a few months ago about those vets
that are on the payroll at one of those askDOTcom websites where a person
asks a question and then pays the vet online when they answer it--lots &
lots of erroneous information being "sold" to customers by these
online vets when they ask about Feralstat. Not a single one of them ever
quote this Topix thread or offer alternatives to their customers when asking
about alternatives to Feralstat.<br />
<br />
I think if there was a simple website setup with a condensed
version of what we all have found out here on our own about a safe
alternative to Feralstat, more & more unwanted litters would be
prevented, plus the public and vets themselves would be more educated about
feline contraception.<br />
<br />
My friend has offered to set up a simple website for this purpose
and I will supply him with the condensed & correct methods/info of mixing
and dosing the MA, thus the public would not have to wade thru this now 2-yr
old Topix thread for info on Feralstat alternatives.<br />
<br />
Last weekend, I visited a large business and the employees there had
"adopted" a small colony of feral cats on the premises..all
employees feed them daily and they are trying their best to TNR the colony,
but they can't get ahead of the game. I told them about MA and this
thread...they are now in process of buying MA and mixing themselves until
they can TNR the whole colony. The employees had no idea a feline
contraceptive existed and neither did their vet (supposedly).<br />
<br />
Keep suggesting domain names folks....I'll keep you posted..<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post293" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#293</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I think the
site is a great idea. Anything that can be done should be done to spread
the word that we finally have an edible birth control for cats. Especially
since it looks as if this is going to have to be a grassroots movement since
the large groups can't/won't endorse it.<br />
<br />
If you need it, I copied all but the last couple posts from this thread that
discussed dosage and where to get MA in to a Word doc.<br />
<br />
As far as a name - what about catbirthcontrol dot com.<br />
<br />
Barbara<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">2<o:p></o:p></span></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post294" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#294</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">What about:<br />
<br />
BirthControlForCats DOT com ?<br />
<br />
Easy to remember and spell...<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judged:<o:p></o:p></span></b></div>
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<span style="color: #999999; font-family: "helvetica" , "sans-serif"; font-size: 7.0pt;">1<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">BusyBee<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/monroe-ga"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Monroe, GA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post295" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#295</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">James wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">What about:<br />
BirthControlForCats DOT com ?<br />
Easy to remember and spell...<br />
James<o:p></o:p></span></i></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I like your idea and
also "Barbara in Orlando" suggestion of CatBirthControl dot
com<br />
BirthControl4Cats dot com (yours in another way :)<br />
<br />
Did you get my email, James?<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post296" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#296</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Busy Bee, I like
your suggestion as well. Yes, I did get your email...you should have received
a reply by now..if not, email me back & I will resend it.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/tyler-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Tyler, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post297" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#297</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Nov 28, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando:
Another good suggestion you have there for a domain name...I may just see if
my friend will register two names and point the DNS settings to one
site, that way we can be covered with two easy to remember names...after a
few more suggestions for domain names, then maybe we can all decide and I'll
send the domain names to my friend and let him register itwith domain
services and then he can work on getting a web site up &
running.<br />
<br />
The MS Word document would be great to have with all the
dosages listed. I can PDF it with Acrobat Pro X and people
visiting the site would have access to a PDF as well
as MS Word documents.<br />
<br />
Last night while researching more on megestrol acetate for feline
contraception, I ran across some foreign websites that referred to a drug
known as "Megecat"...turns out this is a feline contraceptive
prescribed by vets in other countries such as Belgium, Switzerland, etc. I
haven't researched much more on the dosages, but it seems like it has been
used for some time in other countries. I wonder why so many vets here in USA
are unaware of MA in felines for contraception?? Hmm...just strengthens my
hypothesis that there is too much $$$ involved in feline contraception here
in the USA and the drug companies can't patent MA, thus we have to wait years
& years for ACCD and FDA and drug companies to bring AFFORDABLE
contraceptives for cats and dogs to market, if they ever do.<br />
<br />
Barbara, you hit the nail on the head when you said this is turning into a
grassroots effort. I'm glad we all stuck with this for the sake of the
kitties as well as the caretakers.<br />
<br />
I'm sure when the website goes up there will be all the naysayers and hate
mail coming in from all over...I'm sure it will be bombarded...I know that is
a "given"...I'm just surprised this thread itself has stayed so
"clean" and not hijacked by the naysayers.<br />
<br />
When I read your post Barbara, it reminded me of this quote: "Never
doubt that a small group of thoughtful, committed citizens can change the
world; indeed it's the only thing that ever has." -Margaret Mead<br />
<br />
I'll keep you all posted on progress of the website as other suggestions come
in.<br />
<br />
James<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">JKPC<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/la-quinta-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">La Quinta, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post298" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#298</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Where can I get
megestrol acetate/feralstat or ovaban?<br />
Do I have to involve a vet?(Not likely here.)<br />
The neighborhood is being over run by ferals. It is not feasible or
affordable to trap & neuter all of the cats. Esp. with no help from neighbors
or rescue groups. THANKS for any information you can provide.<o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Oct 12<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/city/los-angeles-ca"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Los Angeles, CA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post299" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#299</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">You can google to
find megestrol acetate on non-prescription foreign sites. Any MA strength
will do. You would just have to break it down for the dosing protocol you
choose. I've seen 2 so far, but have not read the entire site right here. Because
only small amounts would be ordered, the product comes into the country
relatively smoothly. What we would use for cats is not enough to make customs
think we are setting up a resale operation.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post300" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#300</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James - I emailed
you the Word doc. with the MA dosage discussions from this forum - please let
me know if you don't get it. Sorry about the delay - for some reason I don't
get all notifications of new postings and just got one today.<br />
<br />
As far as Megecat, that's interesting and not surprising. When I was
searching PubMed for MA studies I noticed that vets outside the US often
offered the full text of their studies for free on-line where very few if any
studies from US vets were available in full. It's all very discouraging.<br />
<br />
Thanks for the inspirational quote.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">James<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/longview-tx"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Longview, TX</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post301" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#301</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 10, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I got it Barbara...I
have replied via email to you.<br />
Thank you so much!<br />
<br />
Website will be up soon--may just be after Christmas though.<br />
<br />
James<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Debbie<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post302" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#302</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">So where can this
product be purchased. I have several kittens this year. More than last year.
ANd I would love to help keep this from happening. Too many cats that aren't
wanted.<o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Debbie in Texas<o:p></o:p></span></b></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">United States<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post303" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#303</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">I would love to find
this product or anything like it. Any help anyone can give would be greatly
appreciated.<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara in Orlando<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/altamonte-springs-fl"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Altamonte Springs, FL</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post304" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#304</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Did you read posting
# 260 ? Excellent info. about approaching a vet about prescribing MA. My
first request was a "no" (and he charged me for the visit) but that
was a learning experience and I'll keep trying.<br />
<br />
#269 and #299 mention ordering from foreign sources.<o:p></o:p></span></div>
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<b><i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">JKPC wrote:<o:p></o:p></span></i></b></div>
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<i><span style="color: #666666; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Where can I get megestrol acetate/feralstat or ovaban?<br />
Do I have to involve a vet?(Not likely here.)<br />
The neighborhood is being over run by ferals. It is not feasible or
affordable to trap & neuter all of the cats. Esp. with no help from
neighbors or rescue groups. THANKS for any information you can provide.<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">steveh<o:p></o:p></span></b></div>
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<a href="http://www.topix.com/forum/city/hudson-ma"><i><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Hudson, MA</span></i></a><i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;"><o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post305" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#305</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Barbara, Did the
money grubbing bastard even give you a reason why. You should have told him
to put his/her bill "where the sun don't shine"!!!! Please post his
name & address - I'll be glad to contact him & it won't be to wish
him/her a Merry Christmas. Good luck in finding a vet willing to write you a
perscription - they're out there so don't give up. Steve<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Reply with quote"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 12.0pt;">Reply »</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14" title="Flag inappropriate post for review"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Report Abuse</span></b></a><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p14"><b><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">Judge it!</span></b></a><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<a href="http://www.topix.com/member/profile/jkpc" title="See JKPC's profile"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;">JKPC</span></b></a><b><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.5pt;"><o:p></o:p></span></b></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 7.5pt;">Since: Dec 12<o:p></o:p></span></div>
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<i><span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 8.5pt;">SoCAL<o:p></o:p></span></i></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/post306" title="Post Permalink"><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">#306</span></a><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"> </span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 9.0pt;">Dec 12, 2012</span><span style="color: #898989; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;"><o:p></o:p></span></div>
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<span style="color: #333333; font-family: "helvetica" , "sans-serif"; font-size: 10.0pt;">Thanks for your
responses to my inquiry!<br />
I have a the head of feral rescue group (affiliated with a local shelter
which the group influenced to become a no-kill) coming tomorrow to do a mass
trapping for TNR.<br />
I met with her today when she delivered a new large group trap & asked
why they weren't using "the pill for cats". She was unaware of
MA/Feralstat and asked why it wasn't mainstream. I said I imagined it had to
do with FDA. She also expressed concerns about side affects. I said if we
woman can use a pill why can't cats? How bad would it be for a male to get a
low dose?(We LOL about that & agreed the world might be a more peaceful
place - no offense to you guys intended, really).<br />
After cries for help to many rescue groups over several years, I was directed
to this local group as they are affiliated in their TNR program with Best
Friends in Kanab, UT. Being new to this thread, there is lots of reading to
get to the important facts.<br />
Would one of you who has participated in this thread over the years please
post the important facts in summary form so I can print and give to this
woman? She is a successful, high profile business woman here in SoCA & is
committed to improving the quality of life for "community"/feral
cats and she has contacts with Best Friends. She possibly could be a
tremendous help to the kitty birth control movement.<br />
THANK YOU!<o:p></o:p></span></div>
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<a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ" title="Go to page page 1 of this discussion"><b><span style="color: #336699; font-family: "helvetica" , "sans-serif"; font-size: 30.0pt;">FeralStat contraceptive: ACCD statement</span></b></a><b><span style="color: #5a5a5a; font-family: "helvetica" , "sans-serif"; font-size: 30.0pt;"><o:p></o:p></span></b></div>
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<span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">There are </span><a href="http://www.topix.com/forum/med/TO5BM504OU9T4PASQ/p12#comments-link-target"><span style="color: #999999; font-family: "times new roman" , "serif"; font-size: 11.5pt;">332 comments</span></a><span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;"> on the </span><a href="http://catsinthenews.blogspot.com/2008/07/feralstat-contraceptive-accd-statement.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Feral Cats in the News</span></a><span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;"> story from Jul 29, 2008, titled <i>FeralStat
contraceptive: ACCD statement</i>. In it, Feral Cats in the News reports that:<o:p></o:p></span></div>
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<span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Thursday, July 24,
2008 FeralStat contraceptive: ACCD statement AnimalResources early requested a
statement about FeralStat from leading feral cat and nonsurgical sterilization
veterinarians and the Alliance ...<o:p></o:p></span></div>
<div class="MsoNormal" style="background: white; margin: 7.5pt 0in 12pt;">
<span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Join the discussion below, or </span><a href="http://catsinthenews.blogspot.com/2008/07/feralstat-contraceptive-accd-statement.html" target="_blank"><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 11.5pt;">Read more</span><span style="color: #336699; font-family: "times new roman" , "serif"; font-size: 11.5pt; text-decoration: none;"> </span></a><span style="color: #5a5a5a; font-family: "times new roman" , "serif"; font-size: 11.5pt;">at Feral Cats in the News.<o:p></o:p></span></div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.comtag:blogger.com,1999:blog-8231746314948212733.post-73575878478505895962018-07-01T19:26:00.000-07:002019-03-05T21:50:38.053-08:00Feralstat information<b><span style="font-family: "arial";">Nonovulin, which is megestrol acetate and lactose, is available through EBAY.</span></b><br />
<b><span style="font-family: "arial";">What follows is the dosage chart for Nonovulin 10 mg tablets. You'll want to use a pill cutter and crusher for the correct dosage. Mix crushed tablet in to wet food, or sprinkle over dry food. </span></b><br />
<b><span style="font-family: "arial";"><br /></span></b>
<span style="color: #222222; font-family: "arial";"><span style="background-color: white;">Total # of Cats Dosage (MG)/Frequency </span><span style="background-color: yellow;"><u>PER COLONY<b> </b></u></span></span><br />
<span style="background-color: white; color: #222222; font-family: "arial";"> </span><br />
<span style="background-color: white; color: #222222; font-family: "arial";">< 5 cats 2.5 mg (1/4 OF A PILL) ONCE a week</span><br />
<span style="background-color: white; color: #222222; font-family: "arial";">5-7 cats 5 mg ( 1/2 A PILL ) ONCE a week</span><br />
<span style="background-color: white; color: #222222; font-family: "arial";"> 8-11 cats 7.5 mg (3/4 OF A PILL) ONCE a week</span><br />
<span style="background-color: white; color: #222222; font-family: "arial";">12-15 cats 5 mg (1/2 A PILL ) <b><u>TWICE</u> </b>A WEEK</span><br />
<span style="background-color: white; color: #222222; font-family: "arial";">16-19 cats 7.5 mg (3/4 OF A PILL) <b><u>TWICE</u></b> A WEEK</span><br />
<span style="background-color: white; color: #222222; font-family: "arial";">20-23 cats 8 mg (APPROX 3/4 OF A PILL) <b><u>TWICE</u></b> A WEEK</span><br />
<br />
<b><span style="font-family: "arial";">The Feralstat<span style="color: magenta; font-size: x-large;">*</span><span style="font-size: x-large;">
</span>site<span style="color: magenta; font-size: medium;"> </span>is no longer
active but Westlab in Gainesville Fl. will supply megestrol acetate
mixed with lactose powder at 1
mg/gm with a prescription called in by a veterinarian.</span></b><br />
<b><span style="font-family: "arial";">The cost March of
2012 was $68.99 for 150 scoops ( 1 scoop doses 2 cats) or $89.99
for 300 scoops. </span></b><br />
<b><span style="font-family: "arial";">Megace liquid and Ovaban are also megestrol acetate
medications, and feral cat caretakers have worked with their
veterinarians to get prescriptions for these products. </span></b><br />
<b><span style="font-family: "arial";"><br /></span></b>
<b><span style="font-family: "arial";"><span style="color: magenta; font-size: x-large;">*</span>Feralstat was
developed by Dr. Caltabiano of Connecticut and his partner Donna Sicuranza .
Sadly, Dr. Caltabiano passed away in November 2009.</span></b><br />
<b><span style="font-family: "arial";">
From his obituary :</span></b><br />
<b><i><span style="font-family: "arial";"> In 1997, as president of Tait's Every Animal Matters, he launched the nonprofit
TEAM Mobile Feline Unit, Connecticut's first and only mobile spay/neuter and
vaccination clinic for cats. With his oversight, TEAM has sterilized more than
128,000 cats and is now a national prototype. His most recent innovation was the
development of FeralStat(r), a feline oral contraceptive created to end feral
cat overpopulation and suffering worldwide. He was also a proud partner in his
family's restaurant, Tony's Huntington Inn, of Bridgeport. </span></i></b><br />
<b><i><span style="font-family: "arial";"><br /></span></i></b>
<br />
<span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;"><b>From web archives, here are pages from the Feralstat site, minus graphics:</b></span><br />
<br />
<br />
<br />
<div class="MsoNormal" style="margin-bottom: .6pt;">
<span lang="EN" style="color: #665345; font-size: 11.0pt;"><!--[if gte vml 1]><v:shapetype id="_x0000_t75"
coordsize="21600,21600" o:spt="75" o:preferrelative="t" path="m@4@5l@4@11@9@11@9@5xe"
filled="f" stroked="f">
<v:stroke joinstyle="miter"/>
<v:formulas>
<v:f eqn="if lineDrawn pixelLineWidth 0"/>
<v:f eqn="sum @0 1 0"/>
<v:f eqn="sum 0 0 @1"/>
<v:f eqn="prod @2 1 2"/>
<v:f eqn="prod @3 21600 pixelWidth"/>
<v:f eqn="prod @3 21600 pixelHeight"/>
<v:f eqn="sum @0 0 1"/>
<v:f eqn="prod @6 1 2"/>
<v:f eqn="prod @7 21600 pixelWidth"/>
<v:f eqn="sum @8 21600 0"/>
<v:f eqn="prod @7 21600 pixelHeight"/>
<v:f eqn="sum @10 21600 0"/>
</v:formulas>
<v:path o:extrusionok="f" gradientshapeok="t" o:connecttype="rect"/>
<o:lock v:ext="edit" aspectratio="t"/>
</v:shapetype><v:shape id="_x0000_s1038" type="#_x0000_t75" alt="FeralStat"
style='width:313.5pt;height:1in'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image001.jpg"
o:href="http://web.archive.org/web/20091025200353im_/http:/www.feralstat.com/images/feral_stat.jpg"/>
</v:shape><![endif]--><!--[if !vml]--><!--[endif]--></span></div>
<div align="right" class="MsoNormal" style="background: #BEB397; text-align: right;">
<span lang="EN" style="color: white; font-size: 11.0pt;">
<a href="http://web.archive.org/web/20091025200353/http:/www.feralstat.com/index.shtml">
<b>
<span style="color: #47372a; font-size: 7.5pt; text-decoration: none; text-transform: uppercase;">
Home</span></b></a> |
<a href="http://web.archive.org/web/20091025200353/http:/www.feralstat.com/feralstat.shtml">
<b>
<span style="color: #47372a; font-size: 7.5pt; text-decoration: none; text-transform: uppercase;">
The FeralStat Story</span></b></a> |
<a href="http://web.archive.org/web/20091025200353/http:/www.feralstat.com/faqs.shtml">
<b>
<span style="color: #47372a; font-size: 7.5pt; text-decoration: none; text-transform: uppercase;">
FAQs</span></b></a> |
<a href="http://web.archive.org/web/20091025200353/http:/www.feralstat.com/drug_information.shtml">
<b>
<span style="color: #47372a; font-size: 7.5pt; text-decoration: none; text-transform: uppercase;">
Drug Information</span></b></a> |
<a href="http://web.archive.org/web/20091025200353/http:/www.feralstat.com/purchase_contact.shtml">
<b>
<span style="color: #47372a; font-size: 7.5pt; text-decoration: none; text-transform: uppercase;">
Purchase</span><span style="color: #47372a; font-size: 10.5pt; text-decoration: none; text-transform: uppercase;">/</span><span style="color: #47372a; font-size: 7.5pt; text-decoration: none; text-transform: uppercase;">Contact
Us</span></b></a> </span></div>
<div class="MsoNormal">
<span lang="EN" style="color: #665345; font-size: 10.0pt;"><!--[if gte vml 1]><v:shape
id="_x0000_s1039" type="#_x0000_t75" alt="" style='width:180pt;height:120.75pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image002.jpg"
o:href="http://web.archive.org/web/20091025200353im_/http:/www.feralstat.com/images/feral_cat.jpg"/>
</v:shape><![endif]--><!--[if !vml]--><!--[endif]--><a href="http://web.archive.org/web/20091025200353/http:/www.feralstat.com/purchase_contact.shtml" title="How do I get FeralStat?"><span style="color: #09529f; text-decoration: none;"> </span></a>
<a href="http://web.archive.org/web/20091025200353/http:/www.feralstat.com/purchase_contact.shtml" title="How do I get FeralStat?">
<span style="color: #09529f; text-decoration: none;"> </span></a> </span></div>
<div class="MsoNormal" style="margin-bottom: 6.0pt;">
<b>
<span lang="EN" style="color: #f70b0d; font-size: 14.0pt;">At Last! An Oral
Contraceptive for Cats.</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">As anyone trying to
curb the growth of a feral cat colony knows, it is often difficult—if not
impossible—to trap every cat for spay/neuter surgery before it reproduces. Now
FeralStat, a feline oral contraceptive, is aiding in the management of feral cat
colonies worldwide. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">FeralStat is safe,
effective, convenient, affordable...it works. It will enable you, the feral cat
caretaker, to become the <i>Last Guardian</i> of your colony. </span></div>
<div class="MsoNormal">
<span lang="EN" style="color: #665345; font-size: 11.0pt;"><!--[if gte vml 1]><v:shape id="_x0000_s1040"
type="#_x0000_t75" alt="This is the first year in seven that we have not had a litter of feral kittens. This is a wonderful product. - Robbie from Portland, OR"
style='width:370.5pt;height:106.5pt'>
<v:imagedata src="file:///C:\DOCUME~1\Owner\LOCALS~1\Temp\msohtml1\01\clip_image003.jpg"
o:href="http://web.archive.org/web/20091025200353im_/http:/www.feralstat.com/images/feral_kittens.jpg"/>
</v:shape><![endif]--><!--[if !vml]--><!--[endif]--></span></div>
<div align="right" class="MsoNormal" style="background: white; text-align: right;">
<span lang="EN" style="color: #665345; font-size: 7.0pt;">© 2009 FeralStat, Inc.</span></div>
<br />
<div class="MsoNormal">
<br /></div>
FAQ:<br />
<div class="MsoNormal">
<br /></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">What is FeralStat?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">It is a synthetic
progestin (progestogen) that prevents cats from becoming pregnant. It is
intended for use in feral cat colonies. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">Is it safe?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Yes. The active
ingredient in FeralStat was FDA approved in the 1950s and has been prescribed by
veterinarians for over 30 years to treat a number of feline disorders. It is
also used extensively today in human medicine and has FDA-approval for
extra-label use as a feline oral contraceptive.The key to this product's success
is the miniscule dosage. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">How do I get a prescription?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">You must speak to our
veterinarian who will prescribe it if it is appropriate for your feral cat
colony. Contact us by phone at 860-399-0097 or by e-mail at
<a href="mailto:info@feralstat.com" style="color: blue;">
<span style="color: #09529f; text-decoration: none;">info@feralstat.com</span></a>
(inquiries must include a contact telephone number for follow up). </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">What does FeralStat cost?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">A four-month supply,
specifically formulated for your colony of 1 to 81 cats, is $67. The price
decreases for larger numbers of feral cats. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">How do I administer FeralStat?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Each packet of
FeralStat is formulated specifically for the number of cats in the colony. Each
prescription includes 16 packets, or a four-month supply. Mix the packet
thoroughly with wet cat food and feed to all cats in the colony once per week.
</span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">What if a pregnant cat, male cat, or
kitten eats FeralStat?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Although it is
designed for female cats, FeralStat has been given to male cats, pregnant
females and kittens who are sharing the food supply with no report of negative
side effects. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">In fact, some
FeralStat clients say that not only are there no unwanted kittens being born,
but also the general health of the colony has improved. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">Should I use FeralStat year round?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Yes. Because it is
administered at such a low dose, it is recommended for year-round use to ensure
that there are no pregnancies. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">What if I miss a dose?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Administer FeralStat
as soon as possible after the missed dose. Then, feed it once per week as
directed. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">Do I still need to spay or neuter?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Ideally, yes. Surgical
sterilization is a permanent solution to overpopulation. FeralStat is intended
to be used in conjunction with spay/neuter or Trap, Neuter, and Return (TNR)
whenever possible. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt; margin-left: 152.65pt;">
<b>
<span lang="EN" style="color: #f70b0d;">Are there any side effects to using
FeralStat?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">As with any drug, side
effects are a possibility (please see drug information). However, the only side
effects that have been reported about FeralStat have been positive: shinier
coats and healthier colonies. </span></div>
<div align="right" class="MsoNormal" style="text-align: right;">
<br /></div>
<div class="MsoNormal" style="text-align: right;">
<br /></div>
<div align="right" class="MsoNormal" style="text-align: right;">
<br /></div>
<div class="MsoNormal" style="margin-bottom: 6.0pt;">
<b>
<span lang="EN" style="color: #f70b0d; font-size: 14.0pt;">At Last! An Oral
Contraceptive for Cats.</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">As anyone trying to
curb the growth of a feral cat colony knows, it is often difficult—if not
impossible—to trap every cat for spay/neuter surgery before it reproduces.
</span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Now FeralStat, a
feline oral contraceptive, is aiding in the management of feral cat colonies
worldwide. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">FeralStat is a
synthetic progestin that prevents female cats from coming into heat. The active
ingredient in FeralStat was patented and FDA-approved in the early 1950s. It is
used extensively in human medicine, and has been prescribed by veterinarians for
over 30 years for cats with skin, urinary tract, and behavioral disorders. It
also has FDA approval for extra-label use as a feline oral contraceptive to
postpone estrus in cats. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">FeralStat is intended
for use as a complement to spay/neuter and Trap, Neuter, and Return (TNR)
programs for feral cats. To administer, simply mix FeralStat with wet cat food
once per week and feed to all the cats in the colony. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">Although it is
designed for female cats, FeralStat has been given to male cats, pregnant
females, and kittens who are sharing the food supply with no report of negative
side effects. That is because a miniscule dose does the trick. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">A cat's minimum
effective daily dosage of FeralStat is approximately 0.04 milligrams—which is
smaller than a grain of sand. In contrast, the daily dosage of this same
compound, when used for treatment of tumors in humans, is two teaspoons or
20,000 times the amount. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">FeralStat was
developed with the assistance of veterinarians, research pharmacologists,
chemists, compounding pharmacists and feral cat caretakers. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">FeralStat is
recommended to curb the growth of feral colonies in places where there is
limited access to sterilization services or too many cats for TNR to be
effective. </span></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt; margin-left: 0in; margin-right: 19.2pt; margin-top: 0in;">
<span lang="EN" style="color: #665345; font-size: 10.0pt;">FeralStat is available
by prescription only. For information on obtaining a FeralStat prescription,
call 860-399-0097 or e-mail
<a href="mailto:info@feralstat.com" style="color: blue;">
<span style="color: #09529f; text-decoration: none;">info@feralstat.com</span></a>
(inquiries must include a contact telephone number for follow up). </span></div>
<table border="0" cellpadding="0" cellspacing="0" class="MsoNormalTable" id="table1" style="border-collapse: collapse;">
<tbody>
<tr>
<td style="padding: 0in 0in 0in 0in; width: 47.0%;" valign="top" width="47%"><div class="MsoNormal" style="background: #F70B0D;">
<b>
<span style="color: white; font-size: 11.5pt; text-transform: uppercase;">FeralStat Drug Information</span></b></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">What is FeralStat?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span style="font-size: 11pt;">
FeralStat is a synthetic progestin (progestogen) used to suppress estrus
(heat) and prevent pregnancy in feral cats. Although it is designed for
female cats, FeralStat has been given to male cats, pregnant females,
and kittens with no report of negative side effects. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">General Precautions:</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span style="font-size: 11pt;">
Wash hands after use. Avoid inhaling or ingesting FeralStat powder.
Avoid contact with eyes. Although the dose used is unlikely to cause
harm to humans, if FeralStat is accidentally ingested, call
860-399-0097. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">How to Administer:</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span style="font-size: 11pt;">
FeralStat should be mixed with wet food and fed to all the cats in the
feral colony once weekly. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">What if I Miss a Dose?</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span style="font-size: 11pt;">
If you miss a dose of FeralStat, give the next dose as soon as you
remember. Start giving FeralStat on this day each week. </span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">Drug Interaction:</span></b></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">carbamazepine</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">corticosteroids (i.e., prednisone)</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">dofetilide</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">fosphenytoin</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">medicines used to treat diabetes</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">indinavir</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">phenobarbital</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">phenytoin</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">primidone</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">rifampin</span></div>
</td>
<td style="border-bottom: medium none; border-left: medium none; border-right: 1.0pt solid black; border-top: medium none; padding: 0in; width: 2.0%;" valign="top" width="2%"><div class="MsoNormal">
</div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 2.0%;" valign="top" width="2%"><div class="MsoNormal">
</div>
</td>
<td style="padding: 0in 0in 0in 0in;" valign="top"><div class="MsoNormal">
<span style="font-size: 11pt;">
<a href="http://web.archive.org/web/20091025200348/http:/www.feralstat.com/purchase_contact.shtml" style="color: blue;" title="How do I get FeralStat?">
<span style="color: #09529f; text-decoration: none;"> </span></a>
<a href="http://web.archive.org/web/20091025200348/http:/www.feralstat.com/purchase_contact.shtml" style="color: blue;" title="How do I get FeralStat?">
<span style="color: #09529f; text-decoration: none;"> </span></a> </span>
</div>
<div class="MsoNormal" style="margin-bottom: 12.0pt;">
<i>
<span style="font-size: 9pt;">Drug Interactions continued:</span></i><span style="font-size: 11pt;">
</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">rifabutin</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">rifapentine</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">warfarin</span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">Contraindications:</span></b></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">uterine disease</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">diabetes mellitus</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">mammary neoplasias</span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">Side Effects:</span></b></div>
<div class="MsoNormal">
<span style="font-size: 11pt;">
Possible side effects for cats receiving FeralStat include: </span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">adrenal suppression</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">Addison</span><span style="color: #665345; font-size: 11pt;">'s-like
syndrome</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">vomiting</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">lethargy</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">diabetes mellitus</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">increased thirst or urination</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">personality changes</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">weight gain</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">endometritis</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">cystic endometrial hyperplasia</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">mammary hypertrophy</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">mammary neoplasias</span></div>
<div class="MsoNormal" style="margin-left: 1.8pt; margin-right: 15.0pt; text-indent: -.25in;">
<span style="color: #f70b0d; font-family: "symbol"; font-size: 10.0pt;">·<span style="font-family: "times new roman"; font-size: 7pt;">
</span></span>
<span style="color: #665345; font-size: 11pt;">hepatotoxicity</span></div>
<div class="MsoNormal" style="margin-bottom: 3.0pt;">
<b>
<span style="color: #f70b0d; font-size: 11pt;">Storage:</span></b></div>
<div class="MsoNormal" style="line-height: 14.7pt; margin-bottom: 9.0pt;">
<span style="font-size: 11pt;">
FeralStat should be stored in a tight container in a cool, dry place.
Store FeralStat between 2º to 30ºC (36º to 86ºF). Keep out of the reach
of children. Store in a container that small children cannot open.
</span></div>
</td>
</tr>
</tbody></table>
<div align="right" class="MsoNormal" style="background: white; text-align: right;">
<span lang="EN" style="color: #665345; font-size: 7.0pt;">© 2009 FeralStat, Inc.</span></div>
<div align="right" class="MsoNormal" style="text-align: right;">
</div>
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<b>FeralStat is available by prescription only. You must speak to our
veterinarian who will prescribe it if it is appropriate for your feral
cat colony.</b> </span></div>
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For information on obtaining a FeralStat prescription: </span></div>
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<span style="color: #665345; font-size: 11pt;">Call 860-399-0097</span></div>
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<span style="color: #665345; font-size: 11pt;">E-mail
<a href="mailto:info@feralstat.com" style="color: blue;">
<span style="color: #09529f; text-decoration: none;">info@feralstat.com</span></a>
(e-mail inquiries must include a contact telephone number for follow
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FeralStat is a registered trademark of FeralStat, Inc.</span></div>
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</v:shapetype><v:shape id="_x0000_s1041" type="#_x0000_t75" alt="I'm very pleased. There are no more cats in the colony since starting FeralStat. - Nancy from Stonington, CT"
style='width:205.5pt;height:119.25pt'/><![endif]--><!--[if !vml]--><img alt="I'm very pleased. There are no more cats in the colony since starting FeralStat. - Nancy from Stonington, CT" border="0" height="159" src="file:///C:/DOCUME~1/Owner/LOCALS~1/Temp/msohtml1/01/clip_image001.gif" v:shapes="_x0000_s1041" width="274" /><!--[endif]--></span></div>
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<span lang="EN" style="color: #665345; font-size: 7.0pt;">© 2009 FeralStat, Inc.</span></div>
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<span lang="EN" style="color: #665345; font-size: 7.0pt;">© 2009 FeralStat, Inc.</span></div>
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tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-87724456657001792562018-07-01T19:09:00.000-07:002018-07-20T14:20:54.724-07:00Megestrol Acetate dosing chart with MG column added<span style="font-family: "arial";">Here is a dosing chart with a MG column added for those using Nonovulin pills. </span><br />
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<span style="font-family: "arial";">I originally mixed a several week batch in water but I found that it developed mold after just a couple days so I began adding the crushed Nonovulin to wet food just before feeding. </span><br />
<span style="font-family: "arial";">I used a pill cutter and then pill</span><span style="font-family: "arial";"> crusher to make a powder. The dosages were not exact but as close as I could get them with this method. </span><br />
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<span style="font-family: "arial";">Total # of Cats Dosage (ML)/Frequency <b>per colony </b> Dosage (MG)/Frequency <b>per colony </b></span><br />
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<span style="font-family: "arial";">< 5 cats .5 ml ONCE a week 2.5 mg ONCE a week</span><br />
<span style="font-family: "arial";">5-7 cats 1.0 ml ONCE a week 5 mg ONCE a week</span><br />
<span style="font-family: "arial";"> 8-11 cats 1.5 ml ONCE a week 7.5 mg ONCE a week</span><br />
<span style="font-family: "arial";">12-15 cats 1.0 ml TWICE A WEEK 5 mg TWICE A WEEK</span><br />
<span style="font-family: "arial";">16-19 cats 1.5 ml TWICE A WEEK 7.5 mg TWICE A WEEK</span><br />
<span style="font-family: "arial";">20-23 cats 1.6 ml TWICE A WEEK 8 mg TWICE A WEEK</span><br />
<span style="font-family: "arial";">24-27 cats 2.0 ml TWICE A WEEK 10 mg TWICE A WEEK </span><br />
<span style="font-family: "arial";">28-31 cats 2.2 ml TWICE A WEEK 11 mg TWICE A WEEK</span><br />
<span style="font-family: "arial";">32-35 cats 2.5 ml TWICE A WEEK 12.5 mg TWICE A WEEK</span><br />
<span style="font-family: "arial";">36-39 cats 2.8 ml TWICE A WEEK 14 mg TWICE A WEEK</span><br />
<span style="font-family: "arial";">40 + cats 3.0 ml TWICE A WEEK 15 mg TWICE A WEEK</span>tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.comtag:blogger.com,1999:blog-8231746314948212733.post-90613790976983610322018-07-01T16:58:00.000-07:002019-03-05T21:22:25.776-08:00Stomatitis/Mouth/Tongue SoresAfter much experimentation with meals, I found that one cat that was particularly plagued with mouth sores (his name was Meatball and he was FIV positive) would eat dry cat food mixed with just enough water so that he could swallow the kibble like we swallow a pill with water. I got the smallest kibble dry food I could find, and added just enough water to cover it. He had to eat it immediately - if the kibble get's too soaked with water and it expanded, it hurt his throat. I usually did multiple small servings at a time several times a day. His being on the kitchen counter was my cue to prepare a meal for him.<br />
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I tried pureeing every kind of fish, poultry and beef but even strained it was still too thick for him to swallow comfortably. If I boiled chicken though, he liked the "soup" made from the water, strained. He also loved the "gravy" in the canned cat food, so I would take the small Friskies Turkey and Giblets Pate (smaller cans for some reason have more separated liquid than the larger can), shake it back and forth, open it, leave the lid partially on and pour from the area where there was a natural "divot". With the larger cans I added an equal amount of water to the wet food, stirred it well, then poured it through a strainer. Oh, and tuna fish juice was another favorite.<br />
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I wish I could say that I'd had luck with L Lysine, Slippery Elm, or Oxyfresh Pet; but I didn't notice any improvement.<br />
<br />
Another FIV cat I had responded immediately to a Convenia injection - she was "asking" for food as soon as we got home from the vet, and ate ravenously and well for about three months. The next shot gave 2 months of relief and the third just a couple of days. I should mention that some cats have had an adverse reaction to Convenia, including death. The FDA has Veterinary Adverse Event Reporting on their site - the information is submitted voluntarily by vet's and available to the public.<br />
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<br />tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0tag:blogger.com,1999:blog-8231746314948212733.post-89875729194597409502018-07-01T13:01:00.000-07:002018-09-12T21:20:27.378-07:00My Background<br />
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<span style="font-family: "arial";"><b style="background-color: yellow;">Update September 2018: For the last eight years I have used Nonovulin on indoor rescues with health issues which would make spay/neuter surgery risky. Female cats dosed have not gone in to heat or become pregnant despite the fact that there was an intact male in the household. </b></span><br />
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<span style="font-family: "arial";">Historically the only option for people like me who were feeding stray cats and</span><span style="font-family: "arial";"> wanted to do the responsible thing and keep them from reproducing was a process called Trap/Neuter/Return or T/N/R. </span></div>
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<span style="font-family: "arial";">In 2009 I happened upon the "Feralstat" site. After a phone consultation with their veterinarian, a non-profit in Connecticut could prescribe a powdered birth control - megestrol acetate (MA) and lactose powder - which when added weekly to wet cat food would prevent pregnancy in female cats after the second dosing. (MA is a synthetic hormone prescribed for people under names like "Megace" and pets under trade names like "Ovaban".) </span><br />
<span style="font-family: "arial";"><br /></span><span style="font-family: "arial";">I did hours of research (see the three posts for megestrol acetate) with sources including PubMed, part of the National Institute of Health site. </span><span style="font-family: "arial";">The risk of side effects from MA seemed to average less than one half of one percent even at much higher dosages than Feralstat ( approx. 1 mg MA per cat once a week.) Since then I've come across a 2003 French report -" </span><b style="color: #402000; font-family: arial;"><a href="http://www.anses.fr/sites/default/files/documents/Rapport-09-12-03-acetate-de-megestrol.pdf">COMMISSION NATIONALE DE PHARMACOVIGILANCE VETERINAIRE RAPPORT D’EXPERTISE DE PHARMACOVIGILANCE relatif à l’AVIS CNPV – 02 du 9/12/2003</a>" -</b><span style="font-family: "arial";"> which concluded that the risk of adverse reactions was .074 per 100K pills sold. (MA has been available in France for over a decade, through pharmacies, without a prescription.)</span></div>
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<span style="font-family: "arial";">I also researched Tait's Every Animal Matters, the Connecticut non-profit which distributed Feralstat, and Dr, John Caltabiano who developed it. I found nothing to call in to question their credibility or ethics. </span></div>
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<span style="background-color: white;"><span style="font-family: "arial";">So I ordered Feralstat<u> </u>and from 2010 - 2011 a colleague and I dosed 15 cats. There were no births or pregnancies. And </span><span style="font-family: "arial";">I have used Nonovulin (megestrol acetate and powdered milk tablets )from Veniviet for the last five years (2014-2018) with no pregnancies or side effects. </span></span></div>
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<span style="font-family: "arial";">My experience is not unique. A Topix forum <i>(link does not always work - Google "Topix ACC&D Statement Feralstat" then click "LAST" for most recent posts, or see the archived pages here dated May 2014)</i> includes caretakers successfully using MA. T<a href="http://www.fairchildcat.org/">he Fairchild Foundation<u> </u></a>in Berk's County Pennsylvania has used it for years. And again, it has been available through pharmacies in Europe for over a decade. </span><br />
<span style="font-family: "arial";"><br /></span><span style="font-family: "arial";">Feralstat ceased being distributed after the untimely death of the Dr. John Caltabiano who had filed the FDA paperwork. Megestrol acetate is available through veterinarian's with a prescription.<span style="background-color: white;"> Nonovulin, manufactured in Bulgaria, is available again through EBAY as of March 2017. It can also be ordered through </span></span><span style="font-family: "arial" , "helvetica" , sans-serif;"><a href="http://venelin.myseliton.com/module.php?ModuleName=com.summercart.newsletter&action=click&click=https%3A%2F%2Fvenivet.com&BlastEmailID=10" style="background-color: white; font-size: 12pt;">venivet.com</a><span style="background-color: white;"> or zoneforpets.com. Both require that you email them with the product you want and pay through a wire transfer service. I have no financial or personal interest in any of these companies. </span><span style="background-color: yellow;">*Mar 2018 I paid $15 for 30 ten mg pills including postage. That's 50 cents a month to dose less than six cats.</span></span><br />
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<span style="background-color: white; font-family: "arial" , "helvetica" , sans-serif;"><b>Dosage <u>PER COLONY</u> </b></span></div>
<span style="background-color: yellow;"><span style="font-family: "arial" , "helvetica" , sans-serif;"><br /></span></span><span style="background-color: yellow;"><span style="font-family: "arial" , "helvetica" , sans-serif;"><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">Total # of Cats ML Dosage(liquid) <u><b>per colony </b> </u> Dosage (dry) <b><u>per colony </u></b></span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;"> </span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">< 5 cats .5 ml ONCE a week 2.5 mg ONCE a week</span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">5-7 cats 1.0 ml ONCE a week 5 mg ONCE a week</span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;"> 8-11 cats 1.5 ml ONCE a week 7.5 mg ONCE a week</span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">12-15 cats 1.0 ml TWICE A WEEK 5 mg TWICE A WEEK</span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">16-19 cats 1.5 ml TWICE A WEEK 7.5 mg TWICE A WEEK</span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">20-23 cats 1.6 ml TWICE A WEEK 8 mg TWICE A WEEK</span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">24-27 cats 2.0 ml TWICE A WEEK 10 mg TWICE A WEEK </span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">28-31 cats 2.2 ml TWICE A WEEK 11 mg TWICE A WEEK</span><br style="background-color: white; color: #222222; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-size: 13.2px;" /><span style="background-color: white; color: #222222; font-family: "arial"; font-size: 13.2px;">32-35 cats 2.5 ml TWICE A WEEK 12.5 mg TWICE A WEEK</span><span style="color: white;"><span style="background-color: white; font-family: "arial"; font-size: 13.2px;">c 2.8 ml TWICE A WEEK 14 mg TWICE A WEEK</span></span></span></span><span style="background-color: yellow;"><span style="font-family: "arial" , "helvetica" , sans-serif;"><br /></span></span></div>
tnrmakessensehttp://www.blogger.com/profile/04411626049380371187noreply@blogger.com0